Ontology type: schema:ScholarlyArticle
2013-06
AUTHORSD. N. Lyabin, L. F. Nigmatullina, A. N. Doronin, I. A. Eliseeva, L. P. Ovchinnikov
ABSTRACTIn this study, proteins specifically interacting with the 3' untranslated region (UTR) of mRNA of the multifunctional Y-box-binding protein 1 (YB-1) were identified. One of these, hnRNP Q, was shown to specifically interact with the regulatory element (RE) in YB-1 mRNA 3' UTR and to inhibit translation of this mRNA. Its binding to the RE was accompanied by displacement from this element of the poly(A)-binding protein (PABP), a positive regulator of YB-1 mRNA translation, and by enhanced binding of the negative YB-1 mRNA translation regulator - YB-1 itself. More... »
PAGES651-659
http://scigraph.springernature.com/pub.10.1134/s0006297913060102
DOIhttp://dx.doi.org/10.1134/s0006297913060102
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/23980891
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