Influence of polycations on antibacterial activity of lysostaphin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-11

AUTHORS

S. N. Kulikov, R. Z. Khairullin, V. P. Varlamov

ABSTRACT

The synergistic antibacterial activity of lysostaphin and polycations of different chemical structures against Staphylococcus aureus has been shown. Polycations improved the lytic activity of lysostaphin against the peptidoglycan of staphylococci. It is proposed that this resulted in decreased binding of positively charged lysostaphin with S. aureus cell-wall teichoic acids. These data provide an opportunity to search for polycations that would amplify the synergistic effect of lysostaphin or other antibacterial proteins against staphylococci. More... »

PAGES

683-687

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1134/s0003683815060083

DOI

http://dx.doi.org/10.1134/s0003683815060083

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013464132


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