Mode of action of a homoeotic gene in Drosophila melanogaster View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1975

AUTHORS

JAAKKO PURO, TUIRE NYGRÉN

ABSTRACT

Polycomb (Pc, Pc2) — one of three closely linked nonallelic homoeotic mutants in chromosome 3 of Drosophila melanogaster that change the development of the hind legs to that of the first legs — is located in the left arm of the chromosome between ri and eg. By using a duplication of the salivary chromosome segment 75A–B through 80, flies were obtained that had two or three doses of Pc alleles. Evidence is given to show that Pc2 and Pc+ are antagonistic in their actions indicating an active competition between homologous gene products. A hypothesis that Pc+ possibly bears a regulatory function comparable to genetic repressors is suggested and briefly discussed. More... »

PAGES

237-247

Identifiers

URI

http://scigraph.springernature.com/pub.10.1111/j.1601-5223.1975.tb01038.x

DOI

http://dx.doi.org/10.1111/j.1601-5223.1975.tb01038.x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010579392

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/814109


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