Gastrointestinal Bleeding in Patients Receiving a Combination of Aspirin, Clopidogrel, and Enoxaparin in Acute Coronary Syndrome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-04

AUTHORS

Fook-Hong Ng, Siu-Yin Wong, Kwok-Fai Lam, Chee-My Chang, Yuk-Kong Lau, Wai-Ming Chu, Benjamin CY Wong

ABSTRACT

BACKGROUND: The combination of aspirin, clopidogrel, and enoxaparin (combination therapy) is the standard treatment for acute coronary syndrome but is associated with gastrointestinal bleeding. However, information in this area is scarce. AIM: This retrospective study aimed to determine the incidence of upper gastrointestinal bleeding in a real-life situation. The effect of proton pump inhibitor (PPI) treatment was also analyzed. METHOD: From January 2002 to December 2006, all patients receiving combination therapy were analyzed. The end point was the occurrence of upper gastrointestinal bleeding during combination therapy or within 7 days of stopping enoxaparin. RESULTS: The patient group consisted of 666 patients (age 72.1 +/- 12.6 yr). Gastrointestinal bleeding occurred in 18 (2.7%) patients. The overall hospital mortality was 4.1% (27 patients). A cardiac event was the major cause (N = 24, 3.6%). Only one patient died of massive gastrointestinal bleeding (0.15%). Multiple logistic regression analysis demonstrated that previous peptic ulcer, cardiogenic shock, and the lack of PPI coprescription were significant risk factors for gastrointestinal bleeding. The age-adjusted odds ratio (95% confidence interval) for gastrointestinal bleeding was 5.07 (1.31-16.58) for previous peptic ulcer, 21.41 (2.56-146.68) for cardiogenic shock, and 0.068 (0.010-0.272) for the coprescription with a PPI. CONCLUSION: In real life, the incidence of gastrointestinal bleeding associated with the combination of aspirin, clopidogrel, and enoxaparin therapy was estimated to be 2.7%. Previous peptic ulcer disease or cardiogenic shock were significant independent risk factors. Coprescription with a PPI can significantly reduce the risk. More... »

PAGES

ajg200850175

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1111/j.1572-0241.2007.01715.x

DOI

http://dx.doi.org/10.1111/j.1572-0241.2007.01715.x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034492141

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18177451


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Acute Coronary Syndrome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anticoagulants", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aspirin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Therapy, Combination", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enoxaparin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gastrointestinal Hemorrhage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Logistic Models", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Platelet Aggregation Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Statistics, Nonparametric", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ticlopidine", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Ruttonjee Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416291.9", 
          "name": [
            "Department of Medicine, Ruttonjee Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ng", 
        "givenName": "Fook-Hong", 
        "id": "sg:person.015465254072.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015465254072.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ruttonjee Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416291.9", 
          "name": [
            "Department of Medicine, Ruttonjee Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wong", 
        "givenName": "Siu-Yin", 
        "id": "sg:person.0710766245.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710766245.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Statistics & Actuarial Science, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lam", 
        "givenName": "Kwok-Fai", 
        "id": "sg:person.01333334225.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333334225.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ruttonjee Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416291.9", 
          "name": [
            "Department of Medicine, Ruttonjee Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chang", 
        "givenName": "Chee-My", 
        "id": "sg:person.01001244731.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01001244731.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ruttonjee Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416291.9", 
          "name": [
            "Department of Medicine, Ruttonjee Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lau", 
        "givenName": "Yuk-Kong", 
        "id": "sg:person.011133560012.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011133560012.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ruttonjee Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416291.9", 
          "name": [
            "Department of Medicine, Ruttonjee Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chu", 
        "givenName": "Wai-Ming", 
        "id": "sg:person.01222741453.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222741453.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Queen Mary Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415550.0", 
          "name": [
            "Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wong", 
        "givenName": "Benjamin CY", 
        "id": "sg:person.014231662152.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014231662152.97"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0002-9343(99)80159-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004785085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm200009213431202", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007378063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2036.2006.02759.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009183509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2036.2006.02759.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009183509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01536266", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013121627", 
          "https://doi.org/10.1007/bf01536266"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa012877", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021782429"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.297.6655.1017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026136508"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2036.2003.01693.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030602136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9343(98)00363-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031587027"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2036.2004.01857.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032746659"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0735-1097(88)90158-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039122778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm200103293441304", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040628564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa010746", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042739677"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.45.2.172", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044099511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1592/phco.20.9.771.35210", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045045196"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa042087", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049671923"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0735-1097(02)02336-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051713092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.106.612812", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052919720"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-04", 
    "datePublishedReg": "2008-04-01", 
    "description": "BACKGROUND: The combination of aspirin, clopidogrel, and enoxaparin (combination therapy) is the standard treatment for acute coronary syndrome but is associated with gastrointestinal bleeding. However, information in this area is scarce.\nAIM: This retrospective study aimed to determine the incidence of upper gastrointestinal bleeding in a real-life situation. The effect of proton pump inhibitor (PPI) treatment was also analyzed.\nMETHOD: From January 2002 to December 2006, all patients receiving combination therapy were analyzed. The end point was the occurrence of upper gastrointestinal bleeding during combination therapy or within 7 days of stopping enoxaparin.\nRESULTS: The patient group consisted of 666 patients (age 72.1 +/- 12.6 yr). Gastrointestinal bleeding occurred in 18 (2.7%) patients. The overall hospital mortality was 4.1% (27 patients). A cardiac event was the major cause (N = 24, 3.6%). Only one patient died of massive gastrointestinal bleeding (0.15%). Multiple logistic regression analysis demonstrated that previous peptic ulcer, cardiogenic shock, and the lack of PPI coprescription were significant risk factors for gastrointestinal bleeding. The age-adjusted odds ratio (95% confidence interval) for gastrointestinal bleeding was 5.07 (1.31-16.58) for previous peptic ulcer, 21.41 (2.56-146.68) for cardiogenic shock, and 0.068 (0.010-0.272) for the coprescription with a PPI.\nCONCLUSION: In real life, the incidence of gastrointestinal bleeding associated with the combination of aspirin, clopidogrel, and enoxaparin therapy was estimated to be 2.7%. Previous peptic ulcer disease or cardiogenic shock were significant independent risk factors. Coprescription with a PPI can significantly reduce the risk.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1111/j.1572-0241.2007.01715.x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1019809", 
        "issn": [
          "0002-9270", 
          "1572-0241"
        ], 
        "name": "The American Journal of Gastroenterology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "103"
      }
    ], 
    "name": "Gastrointestinal Bleeding in Patients Receiving a Combination of Aspirin, Clopidogrel, and Enoxaparin in Acute Coronary Syndrome", 
    "pagination": "ajg200850175", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "a44eed2eafb37edb8ad2f864ca77dd31ecfdc10b71fe9d128370271d5679a499"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18177451"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0421030"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1111/j.1572-0241.2007.01715.x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1034492141"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1111/j.1572-0241.2007.01715.x", 
      "https://app.dimensions.ai/details/publication/pub.1034492141"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:56", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000425.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/ajg200850175"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1111/j.1572-0241.2007.01715.x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1111/j.1572-0241.2007.01715.x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1111/j.1572-0241.2007.01715.x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1111/j.1572-0241.2007.01715.x'


 

This table displays all metadata directly associated to this object as RDF triples.

240 TRIPLES      21 PREDICATES      64 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1111/j.1572-0241.2007.01715.x schema:about N02ffb7aad0da484782c71a93b76f7fb6
2 N03b73e48dbc74de79c184934119319dc
3 N08d2da76c72847fbaf513ad60dc0f4f8
4 N198c7b000209430aa4103edd637135df
5 N1f72b062f52747138597f3d55632ef30
6 N24feb15eee1c4012a2b41602b5a17ec9
7 N283a46cf97754d50a460e40825cf80e3
8 N3abb6e9dafe74f1cacc76c1368f54612
9 N3c43a6b4bfb147858dacba28f0087d8d
10 N3fdd5b7278644be897cd056238a4ac5c
11 N446d0e2eff4f44e9804e66c2c582bece
12 N48b84a3cb4dc48fe8b3c46dab43a22d5
13 N8d34f558faa64579a7055611b21b881a
14 N93a0dcda0d414dcba450c1bbd838d6bf
15 Nda22e3c051b14a7cbf04eb7a867093cc
16 Ned5e4c4096b84e91a53307fec5e4b3a7
17 Nf7dfadc7d823436ba339396ac7635f82
18 Nfb52a8f02c0a47ef80eeb3383ef6e9aa
19 anzsrc-for:11
20 anzsrc-for:1102
21 schema:author Nbf6cece4aff74055958e6dec9403c260
22 schema:citation sg:pub.10.1007/bf01536266
23 https://doi.org/10.1016/0735-1097(88)90158-1
24 https://doi.org/10.1016/s0002-9343(98)00363-5
25 https://doi.org/10.1016/s0002-9343(99)80159-4
26 https://doi.org/10.1016/s0735-1097(02)02336-7
27 https://doi.org/10.1046/j.1365-2036.2003.01693.x
28 https://doi.org/10.1056/nejm200009213431202
29 https://doi.org/10.1056/nejm200103293441304
30 https://doi.org/10.1056/nejmoa010746
31 https://doi.org/10.1056/nejmoa012877
32 https://doi.org/10.1056/nejmoa042087
33 https://doi.org/10.1111/j.1365-2036.2004.01857.x
34 https://doi.org/10.1111/j.1365-2036.2006.02759.x
35 https://doi.org/10.1136/bmj.297.6655.1017
36 https://doi.org/10.1136/gut.45.2.172
37 https://doi.org/10.1161/circulationaha.106.612812
38 https://doi.org/10.1592/phco.20.9.771.35210
39 schema:datePublished 2008-04
40 schema:datePublishedReg 2008-04-01
41 schema:description BACKGROUND: The combination of aspirin, clopidogrel, and enoxaparin (combination therapy) is the standard treatment for acute coronary syndrome but is associated with gastrointestinal bleeding. However, information in this area is scarce. AIM: This retrospective study aimed to determine the incidence of upper gastrointestinal bleeding in a real-life situation. The effect of proton pump inhibitor (PPI) treatment was also analyzed. METHOD: From January 2002 to December 2006, all patients receiving combination therapy were analyzed. The end point was the occurrence of upper gastrointestinal bleeding during combination therapy or within 7 days of stopping enoxaparin. RESULTS: The patient group consisted of 666 patients (age 72.1 +/- 12.6 yr). Gastrointestinal bleeding occurred in 18 (2.7%) patients. The overall hospital mortality was 4.1% (27 patients). A cardiac event was the major cause (N = 24, 3.6%). Only one patient died of massive gastrointestinal bleeding (0.15%). Multiple logistic regression analysis demonstrated that previous peptic ulcer, cardiogenic shock, and the lack of PPI coprescription were significant risk factors for gastrointestinal bleeding. The age-adjusted odds ratio (95% confidence interval) for gastrointestinal bleeding was 5.07 (1.31-16.58) for previous peptic ulcer, 21.41 (2.56-146.68) for cardiogenic shock, and 0.068 (0.010-0.272) for the coprescription with a PPI. CONCLUSION: In real life, the incidence of gastrointestinal bleeding associated with the combination of aspirin, clopidogrel, and enoxaparin therapy was estimated to be 2.7%. Previous peptic ulcer disease or cardiogenic shock were significant independent risk factors. Coprescription with a PPI can significantly reduce the risk.
42 schema:genre research_article
43 schema:inLanguage en
44 schema:isAccessibleForFree false
45 schema:isPartOf Nd6fe5f20f5eb46b78ea8254dfec59140
46 Nec2bc632456648d584915659bbf31fe2
47 sg:journal.1019809
48 schema:name Gastrointestinal Bleeding in Patients Receiving a Combination of Aspirin, Clopidogrel, and Enoxaparin in Acute Coronary Syndrome
49 schema:pagination ajg200850175
50 schema:productId N1c19f30a35b6497e8fb87461d6bbe220
51 Nbba33f8f7b24479c8fb5fe021616ed6b
52 Nc2047bd7241e460490aaaa6e8b5015f5
53 Ne8b948b0f4f4430ab933dfa546d6cf14
54 Nee5e8637d7d8460585268d98ef3fa187
55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034492141
56 https://doi.org/10.1111/j.1572-0241.2007.01715.x
57 schema:sdDatePublished 2019-04-10T18:56
58 schema:sdLicense https://scigraph.springernature.com/explorer/license/
59 schema:sdPublisher N6276b4fedff34e359967aef30f7a4c63
60 schema:url http://www.nature.com/articles/ajg200850175
61 sgo:license sg:explorer/license/
62 sgo:sdDataset articles
63 rdf:type schema:ScholarlyArticle
64 N00e5ba2ae24c402892f3588a71f4b3c9 rdf:first sg:person.014231662152.97
65 rdf:rest rdf:nil
66 N02ffb7aad0da484782c71a93b76f7fb6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Enoxaparin
68 rdf:type schema:DefinedTerm
69 N03b73e48dbc74de79c184934119319dc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Aspirin
71 rdf:type schema:DefinedTerm
72 N08d2da76c72847fbaf513ad60dc0f4f8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Statistics, Nonparametric
74 rdf:type schema:DefinedTerm
75 N198c7b000209430aa4103edd637135df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Male
77 rdf:type schema:DefinedTerm
78 N1c19f30a35b6497e8fb87461d6bbe220 schema:name dimensions_id
79 schema:value pub.1034492141
80 rdf:type schema:PropertyValue
81 N1f72b062f52747138597f3d55632ef30 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Adult
83 rdf:type schema:DefinedTerm
84 N1fa5d5e2361a44969f9a2823b3276665 rdf:first sg:person.01333334225.35
85 rdf:rest Nba9bcde2cdf347128418baaa4fafa541
86 N24feb15eee1c4012a2b41602b5a17ec9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Retrospective Studies
88 rdf:type schema:DefinedTerm
89 N283a46cf97754d50a460e40825cf80e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Ticlopidine
91 rdf:type schema:DefinedTerm
92 N3abb6e9dafe74f1cacc76c1368f54612 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Gastrointestinal Hemorrhage
94 rdf:type schema:DefinedTerm
95 N3c43a6b4bfb147858dacba28f0087d8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Drug Therapy, Combination
97 rdf:type schema:DefinedTerm
98 N3fdd5b7278644be897cd056238a4ac5c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Logistic Models
100 rdf:type schema:DefinedTerm
101 N446d0e2eff4f44e9804e66c2c582bece schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Aged
103 rdf:type schema:DefinedTerm
104 N48b84a3cb4dc48fe8b3c46dab43a22d5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Middle Aged
106 rdf:type schema:DefinedTerm
107 N6276b4fedff34e359967aef30f7a4c63 schema:name Springer Nature - SN SciGraph project
108 rdf:type schema:Organization
109 N8d34f558faa64579a7055611b21b881a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Humans
111 rdf:type schema:DefinedTerm
112 N93a0dcda0d414dcba450c1bbd838d6bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Female
114 rdf:type schema:DefinedTerm
115 Nba9bcde2cdf347128418baaa4fafa541 rdf:first sg:person.01001244731.34
116 rdf:rest Nee73343f6a444e8eb60653e26e7b81a8
117 Nbba33f8f7b24479c8fb5fe021616ed6b schema:name pubmed_id
118 schema:value 18177451
119 rdf:type schema:PropertyValue
120 Nbf6cece4aff74055958e6dec9403c260 rdf:first sg:person.015465254072.15
121 rdf:rest Nced5a191afb241c3af0a40843b5b862a
122 Nc2047bd7241e460490aaaa6e8b5015f5 schema:name readcube_id
123 schema:value a44eed2eafb37edb8ad2f864ca77dd31ecfdc10b71fe9d128370271d5679a499
124 rdf:type schema:PropertyValue
125 Nc8572a181ea941a099a800a4da6cb73b rdf:first sg:person.01222741453.05
126 rdf:rest N00e5ba2ae24c402892f3588a71f4b3c9
127 Nced5a191afb241c3af0a40843b5b862a rdf:first sg:person.0710766245.58
128 rdf:rest N1fa5d5e2361a44969f9a2823b3276665
129 Nd6fe5f20f5eb46b78ea8254dfec59140 schema:volumeNumber 103
130 rdf:type schema:PublicationVolume
131 Nda22e3c051b14a7cbf04eb7a867093cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Platelet Aggregation Inhibitors
133 rdf:type schema:DefinedTerm
134 Ne8b948b0f4f4430ab933dfa546d6cf14 schema:name nlm_unique_id
135 schema:value 0421030
136 rdf:type schema:PropertyValue
137 Nec2bc632456648d584915659bbf31fe2 schema:issueNumber 4
138 rdf:type schema:PublicationIssue
139 Ned5e4c4096b84e91a53307fec5e4b3a7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Aged, 80 and over
141 rdf:type schema:DefinedTerm
142 Nee5e8637d7d8460585268d98ef3fa187 schema:name doi
143 schema:value 10.1111/j.1572-0241.2007.01715.x
144 rdf:type schema:PropertyValue
145 Nee73343f6a444e8eb60653e26e7b81a8 rdf:first sg:person.011133560012.80
146 rdf:rest Nc8572a181ea941a099a800a4da6cb73b
147 Nf7dfadc7d823436ba339396ac7635f82 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Acute Coronary Syndrome
149 rdf:type schema:DefinedTerm
150 Nfb52a8f02c0a47ef80eeb3383ef6e9aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Anticoagulants
152 rdf:type schema:DefinedTerm
153 Nfbafaaaa32c24a28ae7a0d0e37b54f2e schema:name Department of Statistics & Actuarial Science, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
154 rdf:type schema:Organization
155 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
156 schema:name Medical and Health Sciences
157 rdf:type schema:DefinedTerm
158 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
159 schema:name Cardiorespiratory Medicine and Haematology
160 rdf:type schema:DefinedTerm
161 sg:journal.1019809 schema:issn 0002-9270
162 1572-0241
163 schema:name The American Journal of Gastroenterology
164 rdf:type schema:Periodical
165 sg:person.01001244731.34 schema:affiliation https://www.grid.ac/institutes/grid.416291.9
166 schema:familyName Chang
167 schema:givenName Chee-My
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01001244731.34
169 rdf:type schema:Person
170 sg:person.011133560012.80 schema:affiliation https://www.grid.ac/institutes/grid.416291.9
171 schema:familyName Lau
172 schema:givenName Yuk-Kong
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011133560012.80
174 rdf:type schema:Person
175 sg:person.01222741453.05 schema:affiliation https://www.grid.ac/institutes/grid.416291.9
176 schema:familyName Chu
177 schema:givenName Wai-Ming
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222741453.05
179 rdf:type schema:Person
180 sg:person.01333334225.35 schema:affiliation Nfbafaaaa32c24a28ae7a0d0e37b54f2e
181 schema:familyName Lam
182 schema:givenName Kwok-Fai
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333334225.35
184 rdf:type schema:Person
185 sg:person.014231662152.97 schema:affiliation https://www.grid.ac/institutes/grid.415550.0
186 schema:familyName Wong
187 schema:givenName Benjamin CY
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014231662152.97
189 rdf:type schema:Person
190 sg:person.015465254072.15 schema:affiliation https://www.grid.ac/institutes/grid.416291.9
191 schema:familyName Ng
192 schema:givenName Fook-Hong
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015465254072.15
194 rdf:type schema:Person
195 sg:person.0710766245.58 schema:affiliation https://www.grid.ac/institutes/grid.416291.9
196 schema:familyName Wong
197 schema:givenName Siu-Yin
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710766245.58
199 rdf:type schema:Person
200 sg:pub.10.1007/bf01536266 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013121627
201 https://doi.org/10.1007/bf01536266
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/0735-1097(88)90158-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039122778
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1016/s0002-9343(98)00363-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031587027
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1016/s0002-9343(99)80159-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004785085
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1016/s0735-1097(02)02336-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051713092
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1046/j.1365-2036.2003.01693.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030602136
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1056/nejm200009213431202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007378063
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1056/nejm200103293441304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040628564
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1056/nejmoa010746 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042739677
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1056/nejmoa012877 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021782429
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1056/nejmoa042087 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049671923
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1111/j.1365-2036.2004.01857.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032746659
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1111/j.1365-2036.2006.02759.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1009183509
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1136/bmj.297.6655.1017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026136508
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1136/gut.45.2.172 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044099511
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1161/circulationaha.106.612812 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052919720
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1592/phco.20.9.771.35210 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045045196
234 rdf:type schema:CreativeWork
235 https://www.grid.ac/institutes/grid.415550.0 schema:alternateName Queen Mary Hospital
236 schema:name Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
237 rdf:type schema:Organization
238 https://www.grid.ac/institutes/grid.416291.9 schema:alternateName Ruttonjee Hospital
239 schema:name Department of Medicine, Ruttonjee Hospital, Hong Kong, China
240 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...