Long-Term Results of Partial Splenic Artery Embolization as Supplemental Treatment for Portal-Systemic Encephalopathy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-01-01

AUTHORS

Hiroshi Yoshida, Yasuhiro Mamada, Nobuhiko Taniai, Kazuhito Yamamoto, Masahiro Kaneko, Youichi Kawano, Yoshiaki Mizuguchi, Tatsuo Kumazaki, Takashi Tajiri

ABSTRACT

OBJECTIVES: To present long-term results of angiographic partial splenic artery embolization (PSE) as a supplemental treatment of portal-systemic encephalopathy. METHODS: Twenty-five patients with portal-systemic encephalopathy were divided into two groups: 14 patients underwent transportal obliteration and/or balloon-occluded retrograde transvenous obliteration (BRTO) of portal-systemic shunts (PSS), followed by PSE (PSE(+) group), and 11 patients underwent only transportal obliteration and/or BRTO of PSS (PSE(-) group). RESULTS: Portal venous pressures pretreatment was similar to posttreatment in the PSE(+) group, but lower than posttreatment in the PSE(-) group. Serum ammonia levels were higher at pretreatment than at 1 wk posttreatment in both groups, but the levels in the two groups were similar at pretreatment, 1 wk, 3 months, 3 yr, 4 yr, and 5 yr posttreatment. However, serum ammonia levels were lower in the PSE(+) group than in the PSE(-) group 6 months, 9 months, 1 yr, and 2 yr posttreatment. Grades of encephalopathy were higher at pretreatment than at 1 wk posttreatment in both groups, but the levels in the two groups were similar at pretreatment, 1 wk, 2 yr, 3 yr, 4 yr, and 5 yr posttreatment. However, grades of encephalopathy were lower in the PSE(+) group than in the PSE(-) group 3 months, 6 months, 9 months, and 1 yr posttreatment. CONCLUSIONS: Obliteration of PSS followed by PSE benefit patients with portal-systemic encephalopathy. More... »

PAGES

ajg20059

References to SciGraph publications

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URI

http://scigraph.springernature.com/pub.10.1111/j.1572-0241.2005.40559.x

DOI

http://dx.doi.org/10.1111/j.1572-0241.2005.40559.x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024490880

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15654779


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