Severe Cholangitis Following Pancreaticoduodenectomy for Pseudotumoral Form of Lymphoplasmacytic Sclerosing Pancreatitis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-12-01

AUTHORS

Frédéric Marrache, Pascal Hammel, Dermot O'Toole, Dominique Cazals-Hatem, Marie Pierre Vullierme, Annie Sibert, Philippe Ponsot, Frédérique Maire, Olivia Hentic, Alain Sauvanet, Philippe Lévy, Philippe Ruszniewski

ABSTRACT

Cholangitis associated with lymphoplasmacytic sclerosing pancreatitis may occur simultaneously or following diagnosis of pancreatitis. The natural history following inappropriate pancreatic surgery and treatment of cholangitis in this setting are ill-defined. Three patients underwent pancreaticoduodenectomy for pseudotumoral lymphoplasmacytic sclerosing pancreatitis. Jaundice or ascending cholangitis revealed severe biliary strictures at 1, 6, and 11 months, respectively, following surgery. Treatment combining corticosteroids with or without biliary stenting was efficacious in all patients. One patient with subsequent clinical and morphological relapse responded well to reintroduction of steroids. Biliary changes appeared to be immune-related based on pathological examination and response to corticosteroids. More... »

PAGES

2808

Identifiers

URI

http://scigraph.springernature.com/pub.10.1111/j.1572-0241.2005.00270.x

DOI

http://dx.doi.org/10.1111/j.1572-0241.2005.00270.x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017381662

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16393239


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29 schema:description Cholangitis associated with lymphoplasmacytic sclerosing pancreatitis may occur simultaneously or following diagnosis of pancreatitis. The natural history following inappropriate pancreatic surgery and treatment of cholangitis in this setting are ill-defined. Three patients underwent pancreaticoduodenectomy for pseudotumoral lymphoplasmacytic sclerosing pancreatitis. Jaundice or ascending cholangitis revealed severe biliary strictures at 1, 6, and 11 months, respectively, following surgery. Treatment combining corticosteroids with or without biliary stenting was efficacious in all patients. One patient with subsequent clinical and morphological relapse responded well to reintroduction of steroids. Biliary changes appeared to be immune-related based on pathological examination and response to corticosteroids.
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37 Sclerosing Pancreatitis
38 ascending cholangitis
39 biliary changes
40 biliary stenting
41 biliary strictures
42 changes
43 cholangitis
44 corticosteroids
45 diagnosis
46 diagnosis of pancreatitis
47 examination
48 form
49 history
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51 jaundice
52 lymphoplasmacytic
53 months
54 morphological relapse
55 natural history
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58 pancreatitis
59 pathological examination
60 patients
61 pseudotumoral form
62 pseudotumoral lymphoplasmacytic
63 reintroduction
64 reintroduction of steroids
65 relapse
66 response
67 setting
68 severe biliary stricture
69 severe cholangitis
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