Genome Scans Provide Evidence for Keloid Susceptibility Loci on Chromosomes 2q23 and 7p11 View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2004-05

AUTHORS

Alexander G Marneros, James E C Norris, Shoji Watanabe, Ernst Reichenberger, Bjorn R Olsen

ABSTRACT

Keloids are proliferative fibrous growths that result from an excessive tissue response to skin trauma. They often occur sporadically, but in some families a genetic predisposition to keloids has been observed. Here we studied two families with an autosomal dominant inheritance pattern of keloids. One African-American family showed a high degree of variability in the extent of keloid formation between family members, whereas the second family from Japan showed a pattern of full penetrance and the formation of only small keloids. We performed a genome-wide linkage search for genes predisposing to keloid formation in these two families. We identified linkage to chromosome 2q23 (maximal two-point LOD score of 3.01) for the Japanese family. The African-American family showed evidence for a keloid susceptibility locus on chromosome 7p11 (maximal two-point LOD score of 3.16). The observed locus heterogeneity in autosomal dominant keloid disease is consistent with the clinical heterogeneity of this scarring disorder. Dense microsatellite analysis in these two loci was performed and candidate genes were identified. This study provides the first genetic evidence for keloid susceptibility loci and serves as a basis for the identification of responsible genes. More... »

PAGES

1126-1132

Identifiers

URI

http://scigraph.springernature.com/pub.10.1111/j.0022-202x.2004.22327.x

DOI

http://dx.doi.org/10.1111/j.0022-202x.2004.22327.x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035303282

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15140214


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "African Americans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Human, Pair 2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Human, Pair 7", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Family Health", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, Dominant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Linkage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Predisposition to Disease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Haplotypes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Japan", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Keloid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Penetrance", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "familyName": "Marneros", 
        "givenName": "Alexander G", 
        "id": "sg:person.0610313311.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610313311.78"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Norris", 
        "givenName": "James E C", 
        "id": "sg:person.01155057261.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155057261.65"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Watanabe", 
        "givenName": "Shoji", 
        "id": "sg:person.01140562077.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01140562077.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Oral Biology, Harvard Dental School, Boston, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Reichenberger", 
        "givenName": "Ernst", 
        "id": "sg:person.01125044055.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125044055.73"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Olsen", 
        "givenName": "Bjorn R", 
        "id": "sg:person.01271445311.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271445311.76"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1001/archderm.137.11.1429", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001413147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-196104000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002795056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-196104000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002795056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000246625", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005240639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/88832", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013283921", 
          "https://doi.org/10.1038/88832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/88832", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013283921", 
          "https://doi.org/10.1038/88832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-199610000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017213579"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-199610000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017213579"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-199610000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017213579"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0065-2660(01)42016-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020064049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.9.4.1642", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020229542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.116.2.545", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021714268"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9440(10)64803-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022798312"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000637-199908000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027680143"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000637-199908000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027680143"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-200012000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032227750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006534-200012000-00014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032227750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1046/j.1523-1747.2000.00180.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032448130", 
          "https://doi.org/10.1046/j.1523-1747.2000.00180.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/1523-1747.ep12668146", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037415756", 
          "https://doi.org/10.1111/1523-1747.ep12668146"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1524-4725.1999.98257.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037924299"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1524-4725.1999.98257.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037924299"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/1523-1747.ep12396856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044308086", 
          "https://doi.org/10.1111/1523-1747.ep12396856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1295-402", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046708546", 
          "https://doi.org/10.1038/ng1295-402"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.85.2.587", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046990150"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.82.17.5935", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047563369"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/302456", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058610030"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0733-8635(18)30652-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079524654"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0733-8635(18)30653-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079524655"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007611-197007000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1081072816"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007611-197007000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1081072816"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007611-197007000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1081072816"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081840312", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082813248", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082862583", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2004-05", 
    "datePublishedReg": "2004-05-01", 
    "description": "Keloids are proliferative fibrous growths that result from an excessive tissue response to skin trauma. They often occur sporadically, but in some families a genetic predisposition to keloids has been observed. Here we studied two families with an autosomal dominant inheritance pattern of keloids. One African-American family showed a high degree of variability in the extent of keloid formation between family members, whereas the second family from Japan showed a pattern of full penetrance and the formation of only small keloids. We performed a genome-wide linkage search for genes predisposing to keloid formation in these two families. We identified linkage to chromosome 2q23 (maximal two-point LOD score of 3.01) for the Japanese family. The African-American family showed evidence for a keloid susceptibility locus on chromosome 7p11 (maximal two-point LOD score of 3.16). The observed locus heterogeneity in autosomal dominant keloid disease is consistent with the clinical heterogeneity of this scarring disorder. Dense microsatellite analysis in these two loci was performed and candidate genes were identified. This study provides the first genetic evidence for keloid susceptibility loci and serves as a basis for the identification of responsible genes.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1111/j.0022-202x.2004.22327.x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2462791", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2462792", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2625819", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2634100", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2463808", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2634101", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1020153", 
        "issn": [
          "0022-202X", 
          "1523-1747"
        ], 
        "name": "Journal of Investigative Dermatology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "122"
      }
    ], 
    "name": "Genome Scans Provide Evidence for Keloid Susceptibility Loci on Chromosomes 2q23 and 7p11", 
    "pagination": "1126-1132", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "a82b2aa7f331108ce73b3f89fd56c977745b8d0a3ae22996c5904a4524f24fa5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15140214"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0426720"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1111/j.0022-202x.2004.22327.x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1035303282"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1111/j.0022-202x.2004.22327.x", 
      "https://app.dimensions.ai/details/publication/pub.1035303282"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000425.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/jid/journal/v122/n5/full/5602316a.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1111/j.0022-202x.2004.22327.x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1111/j.0022-202x.2004.22327.x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1111/j.0022-202x.2004.22327.x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1111/j.0022-202x.2004.22327.x'


 

This table displays all metadata directly associated to this object as RDF triples.

241 TRIPLES      21 PREDICATES      69 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1111/j.0022-202x.2004.22327.x schema:about N0d0b279dbf5342e5a08261da41eae430
2 N2a4f18c6cbdb4e4798022b6dafc8911f
3 N2f714a2def6944df8c79222fe6664f62
4 N3530512ca0c54126895dadb58a95e4ad
5 N365b52790e524da6a592ef5e1b563f11
6 N488a28a8dec24fb08847a7ce12937fb4
7 N962b2c7b5aa44a4ab54e22132c05db74
8 Na20d61f1d3d2498083474efccf369f20
9 Na68eb657bfd24d6c87e58c4c226d1d3b
10 Na79635a664db4880b2d07fb2b3895497
11 Nccd787a9592e4feea87be3e54b0b3bd8
12 Nccdcfea122ef475bad58487c3373a56b
13 Ncd05d34fc65248babdca7e4a29f136ec
14 Nd3463d628b9649bdb11198b41b33267d
15 Nfa831af782814446a8a2dfb6ced218ee
16 anzsrc-for:06
17 anzsrc-for:0604
18 schema:author Ndcfc57143ee346f0956ebbe101884f5f
19 schema:citation sg:pub.10.1038/88832
20 sg:pub.10.1038/ng1295-402
21 sg:pub.10.1046/j.1523-1747.2000.00180.x
22 sg:pub.10.1111/1523-1747.ep12396856
23 sg:pub.10.1111/1523-1747.ep12668146
24 https://app.dimensions.ai/details/publication/pub.1081840312
25 https://app.dimensions.ai/details/publication/pub.1082813248
26 https://app.dimensions.ai/details/publication/pub.1082862583
27 https://doi.org/10.1001/archderm.137.11.1429
28 https://doi.org/10.1016/s0002-9440(10)64803-1
29 https://doi.org/10.1016/s0065-2660(01)42016-5
30 https://doi.org/10.1016/s0733-8635(18)30652-1
31 https://doi.org/10.1016/s0733-8635(18)30653-3
32 https://doi.org/10.1046/j.1524-4725.1999.98257.x
33 https://doi.org/10.1073/pnas.82.17.5935
34 https://doi.org/10.1073/pnas.85.2.587
35 https://doi.org/10.1083/jcb.116.2.545
36 https://doi.org/10.1086/302456
37 https://doi.org/10.1097/00000637-199908000-00013
38 https://doi.org/10.1097/00006534-196104000-00001
39 https://doi.org/10.1097/00006534-199610000-00012
40 https://doi.org/10.1097/00006534-200012000-00014
41 https://doi.org/10.1097/00007611-197007000-00002
42 https://doi.org/10.1128/mcb.9.4.1642
43 https://doi.org/10.1159/000246625
44 schema:datePublished 2004-05
45 schema:datePublishedReg 2004-05-01
46 schema:description Keloids are proliferative fibrous growths that result from an excessive tissue response to skin trauma. They often occur sporadically, but in some families a genetic predisposition to keloids has been observed. Here we studied two families with an autosomal dominant inheritance pattern of keloids. One African-American family showed a high degree of variability in the extent of keloid formation between family members, whereas the second family from Japan showed a pattern of full penetrance and the formation of only small keloids. We performed a genome-wide linkage search for genes predisposing to keloid formation in these two families. We identified linkage to chromosome 2q23 (maximal two-point LOD score of 3.01) for the Japanese family. The African-American family showed evidence for a keloid susceptibility locus on chromosome 7p11 (maximal two-point LOD score of 3.16). The observed locus heterogeneity in autosomal dominant keloid disease is consistent with the clinical heterogeneity of this scarring disorder. Dense microsatellite analysis in these two loci was performed and candidate genes were identified. This study provides the first genetic evidence for keloid susceptibility loci and serves as a basis for the identification of responsible genes.
47 schema:genre research_article
48 schema:inLanguage en
49 schema:isAccessibleForFree true
50 schema:isPartOf N846a432ea0a042c789d99bdb6d92071c
51 Nfe88655bd44a4294b4dc58fc5a910449
52 sg:journal.1020153
53 schema:name Genome Scans Provide Evidence for Keloid Susceptibility Loci on Chromosomes 2q23 and 7p11
54 schema:pagination 1126-1132
55 schema:productId N60665ec516e544cfa18825d27aaeae60
56 N72195cd1de7e4b1bb63b5268596f43aa
57 N95f232b42cda4cc68f4d5b994a159522
58 Nae59998c419f4f3bafaf000f415ec6c6
59 Nfce39847318e4de886bcdc2d539114e7
60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035303282
61 https://doi.org/10.1111/j.0022-202x.2004.22327.x
62 schema:sdDatePublished 2019-04-10T16:29
63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
64 schema:sdPublisher Na042e975da00445c99cfe4dc59d9ce32
65 schema:url http://www.nature.com/jid/journal/v122/n5/full/5602316a.html
66 sgo:license sg:explorer/license/
67 sgo:sdDataset articles
68 rdf:type schema:ScholarlyArticle
69 N0d0b279dbf5342e5a08261da41eae430 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Japan
71 rdf:type schema:DefinedTerm
72 N0feee8620ea34c4cb7529bfaf986807e schema:name Department of Oral Biology, Harvard Dental School, Boston, USA
73 rdf:type schema:Organization
74 N2a4f18c6cbdb4e4798022b6dafc8911f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name African Americans
76 rdf:type schema:DefinedTerm
77 N2f714a2def6944df8c79222fe6664f62 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Genetic Linkage
79 rdf:type schema:DefinedTerm
80 N3530512ca0c54126895dadb58a95e4ad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Humans
82 rdf:type schema:DefinedTerm
83 N365b52790e524da6a592ef5e1b563f11 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Haplotypes
85 rdf:type schema:DefinedTerm
86 N488a28a8dec24fb08847a7ce12937fb4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Female
88 rdf:type schema:DefinedTerm
89 N60665ec516e544cfa18825d27aaeae60 schema:name readcube_id
90 schema:value a82b2aa7f331108ce73b3f89fd56c977745b8d0a3ae22996c5904a4524f24fa5
91 rdf:type schema:PropertyValue
92 N6ba25240d8ac490b82a8723eacf32875 rdf:first sg:person.01271445311.76
93 rdf:rest rdf:nil
94 N72195cd1de7e4b1bb63b5268596f43aa schema:name doi
95 schema:value 10.1111/j.0022-202x.2004.22327.x
96 rdf:type schema:PropertyValue
97 N846a432ea0a042c789d99bdb6d92071c schema:issueNumber 5
98 rdf:type schema:PublicationIssue
99 N92a1717c61b2473c982f2622ee99320a rdf:first sg:person.01140562077.44
100 rdf:rest Nec62f07acbc943b08790e0a19968909b
101 N95f232b42cda4cc68f4d5b994a159522 schema:name nlm_unique_id
102 schema:value 0426720
103 rdf:type schema:PropertyValue
104 N962b2c7b5aa44a4ab54e22132c05db74 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Chromosomes, Human, Pair 2
106 rdf:type schema:DefinedTerm
107 Na042e975da00445c99cfe4dc59d9ce32 schema:name Springer Nature - SN SciGraph project
108 rdf:type schema:Organization
109 Na20d61f1d3d2498083474efccf369f20 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Keloid
111 rdf:type schema:DefinedTerm
112 Na68eb657bfd24d6c87e58c4c226d1d3b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Genome, Human
114 rdf:type schema:DefinedTerm
115 Na79635a664db4880b2d07fb2b3895497 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Family Health
117 rdf:type schema:DefinedTerm
118 Nae59998c419f4f3bafaf000f415ec6c6 schema:name dimensions_id
119 schema:value pub.1035303282
120 rdf:type schema:PropertyValue
121 Nccd787a9592e4feea87be3e54b0b3bd8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Penetrance
123 rdf:type schema:DefinedTerm
124 Nccdcfea122ef475bad58487c3373a56b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Genetic Predisposition to Disease
126 rdf:type schema:DefinedTerm
127 Ncd05d34fc65248babdca7e4a29f136ec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Chromosomes, Human, Pair 7
129 rdf:type schema:DefinedTerm
130 Nd3463d628b9649bdb11198b41b33267d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Male
132 rdf:type schema:DefinedTerm
133 Ndc1d6786e9424a1fa14faae178cdd520 rdf:first sg:person.01155057261.65
134 rdf:rest N92a1717c61b2473c982f2622ee99320a
135 Ndcfc57143ee346f0956ebbe101884f5f rdf:first sg:person.0610313311.78
136 rdf:rest Ndc1d6786e9424a1fa14faae178cdd520
137 Nec62f07acbc943b08790e0a19968909b rdf:first sg:person.01125044055.73
138 rdf:rest N6ba25240d8ac490b82a8723eacf32875
139 Nfa831af782814446a8a2dfb6ced218ee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Genes, Dominant
141 rdf:type schema:DefinedTerm
142 Nfce39847318e4de886bcdc2d539114e7 schema:name pubmed_id
143 schema:value 15140214
144 rdf:type schema:PropertyValue
145 Nfe88655bd44a4294b4dc58fc5a910449 schema:volumeNumber 122
146 rdf:type schema:PublicationVolume
147 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
148 schema:name Biological Sciences
149 rdf:type schema:DefinedTerm
150 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
151 schema:name Genetics
152 rdf:type schema:DefinedTerm
153 sg:grant.2462791 http://pending.schema.org/fundedItem sg:pub.10.1111/j.0022-202x.2004.22327.x
154 rdf:type schema:MonetaryGrant
155 sg:grant.2462792 http://pending.schema.org/fundedItem sg:pub.10.1111/j.0022-202x.2004.22327.x
156 rdf:type schema:MonetaryGrant
157 sg:grant.2463808 http://pending.schema.org/fundedItem sg:pub.10.1111/j.0022-202x.2004.22327.x
158 rdf:type schema:MonetaryGrant
159 sg:grant.2625819 http://pending.schema.org/fundedItem sg:pub.10.1111/j.0022-202x.2004.22327.x
160 rdf:type schema:MonetaryGrant
161 sg:grant.2634100 http://pending.schema.org/fundedItem sg:pub.10.1111/j.0022-202x.2004.22327.x
162 rdf:type schema:MonetaryGrant
163 sg:grant.2634101 http://pending.schema.org/fundedItem sg:pub.10.1111/j.0022-202x.2004.22327.x
164 rdf:type schema:MonetaryGrant
165 sg:journal.1020153 schema:issn 0022-202X
166 1523-1747
167 schema:name Journal of Investigative Dermatology
168 rdf:type schema:Periodical
169 sg:person.01125044055.73 schema:affiliation N0feee8620ea34c4cb7529bfaf986807e
170 schema:familyName Reichenberger
171 schema:givenName Ernst
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125044055.73
173 rdf:type schema:Person
174 sg:person.01140562077.44 schema:familyName Watanabe
175 schema:givenName Shoji
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01140562077.44
177 rdf:type schema:Person
178 sg:person.01155057261.65 schema:familyName Norris
179 schema:givenName James E C
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155057261.65
181 rdf:type schema:Person
182 sg:person.01271445311.76 schema:familyName Olsen
183 schema:givenName Bjorn R
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271445311.76
185 rdf:type schema:Person
186 sg:person.0610313311.78 schema:familyName Marneros
187 schema:givenName Alexander G
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610313311.78
189 rdf:type schema:Person
190 sg:pub.10.1038/88832 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013283921
191 https://doi.org/10.1038/88832
192 rdf:type schema:CreativeWork
193 sg:pub.10.1038/ng1295-402 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046708546
194 https://doi.org/10.1038/ng1295-402
195 rdf:type schema:CreativeWork
196 sg:pub.10.1046/j.1523-1747.2000.00180.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032448130
197 https://doi.org/10.1046/j.1523-1747.2000.00180.x
198 rdf:type schema:CreativeWork
199 sg:pub.10.1111/1523-1747.ep12396856 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044308086
200 https://doi.org/10.1111/1523-1747.ep12396856
201 rdf:type schema:CreativeWork
202 sg:pub.10.1111/1523-1747.ep12668146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037415756
203 https://doi.org/10.1111/1523-1747.ep12668146
204 rdf:type schema:CreativeWork
205 https://app.dimensions.ai/details/publication/pub.1081840312 schema:CreativeWork
206 https://app.dimensions.ai/details/publication/pub.1082813248 schema:CreativeWork
207 https://app.dimensions.ai/details/publication/pub.1082862583 schema:CreativeWork
208 https://doi.org/10.1001/archderm.137.11.1429 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001413147
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/s0002-9440(10)64803-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022798312
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/s0065-2660(01)42016-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020064049
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1016/s0733-8635(18)30652-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079524654
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1016/s0733-8635(18)30653-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079524655
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1046/j.1524-4725.1999.98257.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037924299
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1073/pnas.82.17.5935 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047563369
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1073/pnas.85.2.587 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046990150
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1083/jcb.116.2.545 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021714268
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1086/302456 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058610030
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1097/00000637-199908000-00013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027680143
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1097/00006534-196104000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002795056
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1097/00006534-199610000-00012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017213579
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1097/00006534-200012000-00014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032227750
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1097/00007611-197007000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1081072816
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1128/mcb.9.4.1642 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020229542
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1159/000246625 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005240639
241 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...