Prolyl and Lysyl Hydroxylase Activities of Human Skin Fibroblasts: Effects of Donor Age and Ascorbate View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1980-11

AUTHORS

Saood Murad, Arunthathy Sivarajah, Sheldon R Pinnell

ABSTRACT

Prolyl and lysyl hydroxylase activities in cultures of human skin fibroblasts from fetal to 94-yr-old donors were measured. In contrast to earlier studies with whole skin, neither prolyl nor lysyl hydroxylase activity was found related to donor age. Prolyl hydroxylase activity increased 3- to 6-fold when cell extracts were incubated with ascorbate and other hydroxylation cofactors before assay. A similar increase in prolyl hydroxylase activity occurred when cells were incubated with ascorbate. Lysyl hydroxylase activity remained unaltered under these conditions. More... »

PAGES

404-407

References to SciGraph publications

  • 1975-10. Collagen synthesized and modified by aging fibroblasts in culture in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY
  • 1974. Biosynthesis of Collagen in CONNECTIVE TISSUES
  • 1976. Intracellular Steps in the Biosynthesis of Collagen in BIOCHEMISTRY OF COLLAGEN
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1111/1523-1747.ep12523660

    DOI

    http://dx.doi.org/10.1111/1523-1747.ep12523660

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1010681747

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/6253574


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adolescent", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aging", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Ascorbic Acid", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Ascorbic Acid Deficiency", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cells, Cultured", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Child", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Child, Preschool", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Collagen", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Fibroblasts", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hydroxylation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Infant", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Infant, Newborn", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mixed Function Oxygenases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Procollagen", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Procollagen-Proline Dioxygenase", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Skin", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "familyName": "Murad", 
            "givenName": "Saood", 
            "id": "sg:person.0630674076.43", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0630674076.43"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Sivarajah", 
            "givenName": "Arunthathy", 
            "id": "sg:person.01313341227.55", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313341227.55"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Pinnell", 
            "givenName": "Sheldon R", 
            "id": "sg:person.0702413542.58", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702413542.58"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/0005-2795(72)90025-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000088008"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0005-2795(72)90025-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000088008"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci108273", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000159843"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcp.1040890302", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000633886"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0003-2697(66)90219-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001532808"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0003-9861(70)90417-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003966240"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-4757-4602-0_5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015181351", 
              "https://doi.org/10.1007/978-1-4757-4602-0_5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(79)90191-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016870100"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(79)90191-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016870100"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0003-9861(75)90126-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020368979"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0003-2697(72)90020-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020487812"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0003-9861(75)90031-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020889659"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.70.4.1090", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025615266"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-3-642-61932-8_14", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028222531", 
              "https://doi.org/10.1007/978-3-642-61932-8_14"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0003-9861(72)90209-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028787557"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(76)90322-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034972499"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(76)90322-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034972499"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(75)90300-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036212358"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(75)90300-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036212358"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(74)90332-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042090624"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(74)90332-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042090624"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf02615641", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042124337", 
              "https://doi.org/10.1007/bf02615641"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf02615641", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042124337", 
              "https://doi.org/10.1007/bf02615641"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/00365516909077656", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043264335"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2362.1977.tb01608.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046410071"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0009-8981(73)90326-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047367786"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0009-8981(73)90326-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047367786"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0006-291x(77)90630-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049854063"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0006-291x(75)90139-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050312767"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci108730", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053617113"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077584274", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078632586", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1980-11", 
        "datePublishedReg": "1980-11-01", 
        "description": "Prolyl and lysyl hydroxylase activities in cultures of human skin fibroblasts from fetal to 94-yr-old donors were measured. In contrast to earlier studies with whole skin, neither prolyl nor lysyl hydroxylase activity was found related to donor age. Prolyl hydroxylase activity increased 3- to 6-fold when cell extracts were incubated with ascorbate and other hydroxylation cofactors before assay. A similar increase in prolyl hydroxylase activity occurred when cells were incubated with ascorbate. Lysyl hydroxylase activity remained unaltered under these conditions.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1111/1523-1747.ep12523660", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2682117", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1020153", 
            "issn": [
              "0022-202X", 
              "1523-1747"
            ], 
            "name": "Journal of Investigative Dermatology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "5", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "75"
          }
        ], 
        "name": "Prolyl and Lysyl Hydroxylase Activities of Human Skin Fibroblasts: Effects of Donor Age and Ascorbate", 
        "pagination": "404-407", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "32e393e32477c4e5ef5bc9a105612e76c72531444d8a4ce0ee3a7b4d8346545d"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "6253574"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "0426720"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1111/1523-1747.ep12523660"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1010681747"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1111/1523-1747.ep12523660", 
          "https://app.dimensions.ai/details/publication/pub.1010681747"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T15:39", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8664_00000428.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://www.nature.com/jid/journal/v75/n5/full/5615824a.html"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1111/1523-1747.ep12523660'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1111/1523-1747.ep12523660'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1111/1523-1747.ep12523660'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1111/1523-1747.ep12523660'


     

    This table displays all metadata directly associated to this object as RDF triples.

    239 TRIPLES      21 PREDICATES      75 URIs      42 LITERALS      30 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1111/1523-1747.ep12523660 schema:about N14c44e9c67954e89856414251f252d32
    2 N152c9f9e73ad46539b8209180e29e914
    3 N2c6cb5173aca4a7780fceb7bd5aff51b
    4 N44b5ed3f2e6c4365b327e8dfc940f524
    5 N5aaf7b82f10849aeb7310539c4973f1b
    6 N5eba139c75e84f8f805269c8eb53a58d
    7 N63cb2a2cfeb541f994eb41afa4dbc002
    8 N6bfa8d37bd624c5d8b10089125547df9
    9 N7937908a2ccf49d89220a68e15a7254e
    10 N842998beed614946a056fd615f7fe4aa
    11 N86e5e17c3c50405cbb9add23f6081b97
    12 N9cd140330d314f0e90063047a604a36d
    13 Nb0003cfcf1034ac8807206233a8c7cb3
    14 Nb398781064b4460ebf19f8c2f2232a5b
    15 Nb60edfc322c5447ca89e1e5d123b8459
    16 Nc4c98d3f208742e8935bf8c9c6abee89
    17 Ncb8c9eeb41024dd1bf8873458af25930
    18 Nd6feefa357b64e029c47d2af0f6c010b
    19 Ne6978d758cde440facb871e1c8a5c9b2
    20 Ne90b7630fe1d4bf5acf9a0485f9980d9
    21 Nf1bf698650904e99be2eb9353de8449a
    22 anzsrc-for:11
    23 anzsrc-for:1103
    24 schema:author N53db865f3017451b92baa39e63087b63
    25 schema:citation sg:pub.10.1007/978-1-4757-4602-0_5
    26 sg:pub.10.1007/978-3-642-61932-8_14
    27 sg:pub.10.1007/bf02615641
    28 https://app.dimensions.ai/details/publication/pub.1077584274
    29 https://app.dimensions.ai/details/publication/pub.1078632586
    30 https://doi.org/10.1002/jcp.1040890302
    31 https://doi.org/10.1016/0003-2697(66)90219-3
    32 https://doi.org/10.1016/0003-2697(72)90020-6
    33 https://doi.org/10.1016/0003-9861(70)90417-0
    34 https://doi.org/10.1016/0003-9861(72)90209-3
    35 https://doi.org/10.1016/0003-9861(75)90031-4
    36 https://doi.org/10.1016/0003-9861(75)90126-5
    37 https://doi.org/10.1016/0005-2795(72)90025-6
    38 https://doi.org/10.1016/0006-291x(75)90139-4
    39 https://doi.org/10.1016/0006-291x(77)90630-1
    40 https://doi.org/10.1016/0009-8981(73)90326-4
    41 https://doi.org/10.1016/0304-4165(74)90332-8
    42 https://doi.org/10.1016/0304-4165(75)90300-1
    43 https://doi.org/10.1016/0304-4165(76)90322-6
    44 https://doi.org/10.1016/0304-4165(79)90191-0
    45 https://doi.org/10.1073/pnas.70.4.1090
    46 https://doi.org/10.1111/j.1365-2362.1977.tb01608.x
    47 https://doi.org/10.1172/jci108273
    48 https://doi.org/10.1172/jci108730
    49 https://doi.org/10.3109/00365516909077656
    50 schema:datePublished 1980-11
    51 schema:datePublishedReg 1980-11-01
    52 schema:description Prolyl and lysyl hydroxylase activities in cultures of human skin fibroblasts from fetal to 94-yr-old donors were measured. In contrast to earlier studies with whole skin, neither prolyl nor lysyl hydroxylase activity was found related to donor age. Prolyl hydroxylase activity increased 3- to 6-fold when cell extracts were incubated with ascorbate and other hydroxylation cofactors before assay. A similar increase in prolyl hydroxylase activity occurred when cells were incubated with ascorbate. Lysyl hydroxylase activity remained unaltered under these conditions.
    53 schema:genre research_article
    54 schema:inLanguage en
    55 schema:isAccessibleForFree true
    56 schema:isPartOf N908c96c77225482a80632762036de22e
    57 Nbd94547a3db044469ee0585c8551e8bd
    58 sg:journal.1020153
    59 schema:name Prolyl and Lysyl Hydroxylase Activities of Human Skin Fibroblasts: Effects of Donor Age and Ascorbate
    60 schema:pagination 404-407
    61 schema:productId N4386e56c23dc49f0b6a668c0fa2a231b
    62 N48da91a8da8745bab77d972c5b1019f4
    63 N4f17aa8349ca4871a10414036341e883
    64 Nb4e01a47df6c4c6da7d26be2af51f3a2
    65 Ne3e327a5ccd5484eaf2b9bc0942e36c7
    66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010681747
    67 https://doi.org/10.1111/1523-1747.ep12523660
    68 schema:sdDatePublished 2019-04-10T15:39
    69 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    70 schema:sdPublisher N5f07741e011646f19169c022873342de
    71 schema:url http://www.nature.com/jid/journal/v75/n5/full/5615824a.html
    72 sgo:license sg:explorer/license/
    73 sgo:sdDataset articles
    74 rdf:type schema:ScholarlyArticle
    75 N14c44e9c67954e89856414251f252d32 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    76 schema:name Fibroblasts
    77 rdf:type schema:DefinedTerm
    78 N152c9f9e73ad46539b8209180e29e914 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    79 schema:name Child, Preschool
    80 rdf:type schema:DefinedTerm
    81 N2c6cb5173aca4a7780fceb7bd5aff51b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    82 schema:name Procollagen
    83 rdf:type schema:DefinedTerm
    84 N4386e56c23dc49f0b6a668c0fa2a231b schema:name pubmed_id
    85 schema:value 6253574
    86 rdf:type schema:PropertyValue
    87 N44b5ed3f2e6c4365b327e8dfc940f524 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    88 schema:name Mixed Function Oxygenases
    89 rdf:type schema:DefinedTerm
    90 N48da91a8da8745bab77d972c5b1019f4 schema:name nlm_unique_id
    91 schema:value 0426720
    92 rdf:type schema:PropertyValue
    93 N4f17aa8349ca4871a10414036341e883 schema:name doi
    94 schema:value 10.1111/1523-1747.ep12523660
    95 rdf:type schema:PropertyValue
    96 N53db865f3017451b92baa39e63087b63 rdf:first sg:person.0630674076.43
    97 rdf:rest N7e8395a566af4bcd92b67fabcaad7e3b
    98 N5aaf7b82f10849aeb7310539c4973f1b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    99 schema:name Ascorbic Acid Deficiency
    100 rdf:type schema:DefinedTerm
    101 N5eba139c75e84f8f805269c8eb53a58d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    102 schema:name Skin
    103 rdf:type schema:DefinedTerm
    104 N5f07741e011646f19169c022873342de schema:name Springer Nature - SN SciGraph project
    105 rdf:type schema:Organization
    106 N63cb2a2cfeb541f994eb41afa4dbc002 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    107 schema:name Collagen
    108 rdf:type schema:DefinedTerm
    109 N6bfa8d37bd624c5d8b10089125547df9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    110 schema:name Infant
    111 rdf:type schema:DefinedTerm
    112 N7937908a2ccf49d89220a68e15a7254e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    113 schema:name Child
    114 rdf:type schema:DefinedTerm
    115 N7e8395a566af4bcd92b67fabcaad7e3b rdf:first sg:person.01313341227.55
    116 rdf:rest Nbb21b28f93e14a369de9353925f72c0b
    117 N842998beed614946a056fd615f7fe4aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    118 schema:name Procollagen-Proline Dioxygenase
    119 rdf:type schema:DefinedTerm
    120 N86e5e17c3c50405cbb9add23f6081b97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    121 schema:name Cells, Cultured
    122 rdf:type schema:DefinedTerm
    123 N908c96c77225482a80632762036de22e schema:issueNumber 5
    124 rdf:type schema:PublicationIssue
    125 N9cd140330d314f0e90063047a604a36d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    126 schema:name Adolescent
    127 rdf:type schema:DefinedTerm
    128 Nb0003cfcf1034ac8807206233a8c7cb3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    129 schema:name Aging
    130 rdf:type schema:DefinedTerm
    131 Nb398781064b4460ebf19f8c2f2232a5b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    132 schema:name Ascorbic Acid
    133 rdf:type schema:DefinedTerm
    134 Nb4e01a47df6c4c6da7d26be2af51f3a2 schema:name readcube_id
    135 schema:value 32e393e32477c4e5ef5bc9a105612e76c72531444d8a4ce0ee3a7b4d8346545d
    136 rdf:type schema:PropertyValue
    137 Nb60edfc322c5447ca89e1e5d123b8459 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    138 schema:name Humans
    139 rdf:type schema:DefinedTerm
    140 Nbb21b28f93e14a369de9353925f72c0b rdf:first sg:person.0702413542.58
    141 rdf:rest rdf:nil
    142 Nbd94547a3db044469ee0585c8551e8bd schema:volumeNumber 75
    143 rdf:type schema:PublicationVolume
    144 Nc4c98d3f208742e8935bf8c9c6abee89 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    145 schema:name Adult
    146 rdf:type schema:DefinedTerm
    147 Ncb8c9eeb41024dd1bf8873458af25930 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    148 schema:name Hydroxylation
    149 rdf:type schema:DefinedTerm
    150 Nd6feefa357b64e029c47d2af0f6c010b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    151 schema:name Middle Aged
    152 rdf:type schema:DefinedTerm
    153 Ne3e327a5ccd5484eaf2b9bc0942e36c7 schema:name dimensions_id
    154 schema:value pub.1010681747
    155 rdf:type schema:PropertyValue
    156 Ne6978d758cde440facb871e1c8a5c9b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    157 schema:name Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase
    158 rdf:type schema:DefinedTerm
    159 Ne90b7630fe1d4bf5acf9a0485f9980d9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    160 schema:name Infant, Newborn
    161 rdf:type schema:DefinedTerm
    162 Nf1bf698650904e99be2eb9353de8449a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    163 schema:name Aged
    164 rdf:type schema:DefinedTerm
    165 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    166 schema:name Medical and Health Sciences
    167 rdf:type schema:DefinedTerm
    168 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    169 schema:name Clinical Sciences
    170 rdf:type schema:DefinedTerm
    171 sg:grant.2682117 http://pending.schema.org/fundedItem sg:pub.10.1111/1523-1747.ep12523660
    172 rdf:type schema:MonetaryGrant
    173 sg:journal.1020153 schema:issn 0022-202X
    174 1523-1747
    175 schema:name Journal of Investigative Dermatology
    176 rdf:type schema:Periodical
    177 sg:person.01313341227.55 schema:familyName Sivarajah
    178 schema:givenName Arunthathy
    179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313341227.55
    180 rdf:type schema:Person
    181 sg:person.0630674076.43 schema:familyName Murad
    182 schema:givenName Saood
    183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0630674076.43
    184 rdf:type schema:Person
    185 sg:person.0702413542.58 schema:familyName Pinnell
    186 schema:givenName Sheldon R
    187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702413542.58
    188 rdf:type schema:Person
    189 sg:pub.10.1007/978-1-4757-4602-0_5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015181351
    190 https://doi.org/10.1007/978-1-4757-4602-0_5
    191 rdf:type schema:CreativeWork
    192 sg:pub.10.1007/978-3-642-61932-8_14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028222531
    193 https://doi.org/10.1007/978-3-642-61932-8_14
    194 rdf:type schema:CreativeWork
    195 sg:pub.10.1007/bf02615641 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042124337
    196 https://doi.org/10.1007/bf02615641
    197 rdf:type schema:CreativeWork
    198 https://app.dimensions.ai/details/publication/pub.1077584274 schema:CreativeWork
    199 https://app.dimensions.ai/details/publication/pub.1078632586 schema:CreativeWork
    200 https://doi.org/10.1002/jcp.1040890302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000633886
    201 rdf:type schema:CreativeWork
    202 https://doi.org/10.1016/0003-2697(66)90219-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001532808
    203 rdf:type schema:CreativeWork
    204 https://doi.org/10.1016/0003-2697(72)90020-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020487812
    205 rdf:type schema:CreativeWork
    206 https://doi.org/10.1016/0003-9861(70)90417-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003966240
    207 rdf:type schema:CreativeWork
    208 https://doi.org/10.1016/0003-9861(72)90209-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028787557
    209 rdf:type schema:CreativeWork
    210 https://doi.org/10.1016/0003-9861(75)90031-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020889659
    211 rdf:type schema:CreativeWork
    212 https://doi.org/10.1016/0003-9861(75)90126-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020368979
    213 rdf:type schema:CreativeWork
    214 https://doi.org/10.1016/0005-2795(72)90025-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000088008
    215 rdf:type schema:CreativeWork
    216 https://doi.org/10.1016/0006-291x(75)90139-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050312767
    217 rdf:type schema:CreativeWork
    218 https://doi.org/10.1016/0006-291x(77)90630-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049854063
    219 rdf:type schema:CreativeWork
    220 https://doi.org/10.1016/0009-8981(73)90326-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047367786
    221 rdf:type schema:CreativeWork
    222 https://doi.org/10.1016/0304-4165(74)90332-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042090624
    223 rdf:type schema:CreativeWork
    224 https://doi.org/10.1016/0304-4165(75)90300-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036212358
    225 rdf:type schema:CreativeWork
    226 https://doi.org/10.1016/0304-4165(76)90322-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034972499
    227 rdf:type schema:CreativeWork
    228 https://doi.org/10.1016/0304-4165(79)90191-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016870100
    229 rdf:type schema:CreativeWork
    230 https://doi.org/10.1073/pnas.70.4.1090 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025615266
    231 rdf:type schema:CreativeWork
    232 https://doi.org/10.1111/j.1365-2362.1977.tb01608.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1046410071
    233 rdf:type schema:CreativeWork
    234 https://doi.org/10.1172/jci108273 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000159843
    235 rdf:type schema:CreativeWork
    236 https://doi.org/10.1172/jci108730 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053617113
    237 rdf:type schema:CreativeWork
    238 https://doi.org/10.3109/00365516909077656 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043264335
    239 rdf:type schema:CreativeWork
     




    Preview window. Press ESC to close (or click here)


    ...