Identification of T lymphocytes in simian immunodeficiency virus encephalitis: Distribution of CD8+ T cells in association with central nervous system ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-09

AUTHORS

Woong-Ki Kim, Sarah Corey, Gillian Chesney, Heather Knight, Sherry Klumpp, Christian Wüthrich, Norman L. Letvin, Igor J. Koralnik, Andrew Lackner, Ronald S. Veasey, Kenneth Williams

ABSTRACT

T lymphocytes are found within brains infected with human immunodeficiency virus (HIV) or simian immunodeficiency virus (SIV) where they are a minor, but consistently identified, population. However, little analysis of their phenotypes has been done, and questions concerning whether or not they are viral antigen specific has not been thoroughly examined. We investigated the central nervous system (CNS) of SIV-infected rhesus macaques to identify T-lymphocyte subsets in relation to virus-infected cells and brain microvessels. We have found that a sensitive antigen-retrieval technique greatly enhanced immunohistochemical detection of CD4+ and CD8+ T lymphocytes in control studies. In encephalitic brains of SIV-infected monkeys with acquired immunodeficiency syndrome (AIDS), we found a significant accumulation of CD8+ T lymphocytes but little-to-no accumulation of CD4+ T lymphocytes. CD4+ cells, when detected, were mostly monocyte/macrophages closely associated with CNS vessels. Using a combination of in situ hybridization for SIV RNA, and immunohistochemistry for CD8+ T lymphocytes and/or Glut-1 for endothelial cells on brain microvessels, we found CD8+ T lymphocytes with an angiocentric distribution often adjacent to virus-infected cells. In the CNS of animals with SIV encephalitis, there was a trend of CD8+ T lymphocytes that were not directly juxtaposed with CNS vessels. These data suggest that in brains of SIV-infected monkeys and HIV-infected humans, CD8+ T lymphocytes traffic to and are retained in the CNS in an angiocentric and possibly antigen-specific manner. More... »

PAGES

315-325

Identifiers

URI

http://scigraph.springernature.com/pub.10.1080/13550280490505382

DOI

http://dx.doi.org/10.1080/13550280490505382

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027110755

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15385254


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "CD8-Positive T-Lymphocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Central Nervous System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Models, Animal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Macaca mulatta", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Simian Acquired Immunodeficiency Syndrome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Simian Immunodeficiency Virus", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Woong-Ki", 
        "id": "sg:person.01112443667.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112443667.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Corey", 
        "givenName": "Sarah", 
        "id": "sg:person.01233405734.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233405734.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chesney", 
        "givenName": "Gillian", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Harvard University", 
          "id": "https://www.grid.ac/institutes/grid.38142.3c", 
          "name": [
            "Department of Comparative Pathology, Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Knight", 
        "givenName": "Heather", 
        "id": "sg:person.014661040357.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014661040357.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Harvard University", 
          "id": "https://www.grid.ac/institutes/grid.38142.3c", 
          "name": [
            "Department of Comparative Pathology, Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Klumpp", 
        "givenName": "Sherry", 
        "id": "sg:person.0615357007.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615357007.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "W\u00fcthrich", 
        "givenName": "Christian", 
        "id": "sg:person.01121357756.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121357756.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Letvin", 
        "givenName": "Norman L.", 
        "id": "sg:person.01106522134.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106522134.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA", 
            "Division of Viral Pathogenesis, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koralnik", 
        "givenName": "Igor J.", 
        "id": "sg:person.01342420117.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342420117.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tulane University", 
          "id": "https://www.grid.ac/institutes/grid.265219.b", 
          "name": [
            "Tulane Regional Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lackner", 
        "givenName": "Andrew", 
        "id": "sg:person.01211324340.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01211324340.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tulane University", 
          "id": "https://www.grid.ac/institutes/grid.265219.b", 
          "name": [
            "Tulane Regional Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Veasey", 
        "givenName": "Ronald S.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Williams", 
        "givenName": "Kenneth", 
        "id": "sg:person.01350163345.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350163345.19"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00401-004-0852-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005521510", 
          "https://doi.org/10.1007/s00401-004-0852-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0923-2516(91)90054-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006990514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0923-2516(91)90054-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006990514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1080/13550280390173391", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009172020", 
          "https://doi.org/10.1080/13550280390173391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-78536-8_3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010531101", 
          "https://doi.org/10.1007/978-3-642-78536-8_3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/514113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013274661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ana.410210513", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017093329"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0079-6123(08)62595-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018585135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35073667", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018601522", 
          "https://doi.org/10.1038/35073667"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35073667", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018601522", 
          "https://doi.org/10.1038/35073667"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1080/135502801753248114", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021871650", 
          "https://doi.org/10.1080/135502801753248114"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200307250-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030296893"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00002030-200307250-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030296893"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1750-3639.1991.tb00646.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031998832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00334676", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032055063", 
          "https://doi.org/10.1007/bf00334676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.75.23.11686-11699.2001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032928630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/344938", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033525713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1699-0463.1989.tb00759.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033797084"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1699-0463.1989.tb00759.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033797084"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/glia.1112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035598387"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0923-2516(91)90051-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037735855"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0923-2516(91)90051-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037735855"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ana.410310402", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038858368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jcp.45.12.1084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040866707"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.193.8.905", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041224337"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2990.2000.00243.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041516324"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1300/j128v01n01_02", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041565014"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/335178a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045579829", 
          "https://doi.org/10.1038/335178a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.192.3.393", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047369678"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ana.10100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049209854"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0165-5728(01)00496-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050377172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnen/61.1.85", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050567138"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/infdis/168.4.818", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059704090"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.270.5239.1158", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062551632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.287.5453.602", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062568160"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.3109/13550289609146909", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070985960", 
          "https://doi.org/10.3109/13550289609146909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.3109/13550289909015809", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070986088", 
          "https://doi.org/10.3109/13550289909015809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075537751", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076050174", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077335728", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077418599", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077658579", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077895593", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079357348", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079815105", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082483449", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082795355", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082826578", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083031253", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083252200", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083277713", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083345406", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083370005", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2004-09", 
    "datePublishedReg": "2004-09-01", 
    "description": "T lymphocytes are found within brains infected with human immunodeficiency virus (HIV) or simian immunodeficiency virus (SIV) where they are a minor, but consistently identified, population. However, little analysis of their phenotypes has been done, and questions concerning whether or not they are viral antigen specific has not been thoroughly examined. We investigated the central nervous system (CNS) of SIV-infected rhesus macaques to identify T-lymphocyte subsets in relation to virus-infected cells and brain microvessels. We have found that a sensitive antigen-retrieval technique greatly enhanced immunohistochemical detection of CD4+ and CD8+ T lymphocytes in control studies. In encephalitic brains of SIV-infected monkeys with acquired immunodeficiency syndrome (AIDS), we found a significant accumulation of CD8+ T lymphocytes but little-to-no accumulation of CD4+ T lymphocytes. CD4+ cells, when detected, were mostly monocyte/macrophages closely associated with CNS vessels. Using a combination of in situ hybridization for SIV RNA, and immunohistochemistry for CD8+ T lymphocytes and/or Glut-1 for endothelial cells on brain microvessels, we found CD8+ T lymphocytes with an angiocentric distribution often adjacent to virus-infected cells. In the CNS of animals with SIV encephalitis, there was a trend of CD8+ T lymphocytes that were not directly juxtaposed with CNS vessels. These data suggest that in brains of SIV-infected monkeys and HIV-infected humans, CD8+ T lymphocytes traffic to and are retained in the CNS in an angiocentric and possibly antigen-specific manner.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1080/13550280490505382", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2455307", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2559492", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2441136", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2558380", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2558802", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2685813", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2668027", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2421695", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2559753", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1114176", 
        "issn": [
          "1355-0284", 
          "1538-2443"
        ], 
        "name": "Journal of NeuroVirology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "10"
      }
    ], 
    "name": "Identification of T lymphocytes in simian immunodeficiency virus encephalitis: Distribution of CD8+ T cells in association with central nervous system vessels and virus", 
    "pagination": "315-325", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "8125ae3f0b4c392b4ab6675e4386289449a2ed0a330471f08643510e725c0772"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15385254"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9508123"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1080/13550280490505382"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1027110755"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1080/13550280490505382", 
      "https://app.dimensions.ai/details/publication/pub.1027110755"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T21:34", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8687_00000499.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1080/13550280490505382"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1080/13550280490505382'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1080/13550280490505382'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1080/13550280490505382'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1080/13550280490505382'


 

This table displays all metadata directly associated to this object as RDF triples.

338 TRIPLES      21 PREDICATES      84 URIs      28 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1080/13550280490505382 schema:about N0573dc05162848d1896d351d088d8e76
2 N0a7a81c0a7384f30a3299f107044def6
3 N0a816aac847c4741aaaf42bd0b1d862e
4 N8bdc7698243045a880c264609a8bcc8e
5 Na011e15986d14f9dab0d450ced57947c
6 Nbe792a25475540feb371e33c27f67522
7 Ncc3300afe8c14d60b1596baaa7b69542
8 anzsrc-for:11
9 anzsrc-for:1107
10 schema:author Nddb6ca80fa53425fbc0ee333efaca398
11 schema:citation sg:pub.10.1007/978-3-642-78536-8_3
12 sg:pub.10.1007/bf00334676
13 sg:pub.10.1007/s00401-004-0852-0
14 sg:pub.10.1038/335178a0
15 sg:pub.10.1038/35073667
16 sg:pub.10.1080/135502801753248114
17 sg:pub.10.1080/13550280390173391
18 sg:pub.10.3109/13550289609146909
19 sg:pub.10.3109/13550289909015809
20 https://app.dimensions.ai/details/publication/pub.1075537751
21 https://app.dimensions.ai/details/publication/pub.1076050174
22 https://app.dimensions.ai/details/publication/pub.1077335728
23 https://app.dimensions.ai/details/publication/pub.1077418599
24 https://app.dimensions.ai/details/publication/pub.1077658579
25 https://app.dimensions.ai/details/publication/pub.1077895593
26 https://app.dimensions.ai/details/publication/pub.1079357348
27 https://app.dimensions.ai/details/publication/pub.1079815105
28 https://app.dimensions.ai/details/publication/pub.1082483449
29 https://app.dimensions.ai/details/publication/pub.1082795355
30 https://app.dimensions.ai/details/publication/pub.1082826578
31 https://app.dimensions.ai/details/publication/pub.1083031253
32 https://app.dimensions.ai/details/publication/pub.1083252200
33 https://app.dimensions.ai/details/publication/pub.1083277713
34 https://app.dimensions.ai/details/publication/pub.1083345406
35 https://app.dimensions.ai/details/publication/pub.1083370005
36 https://doi.org/10.1002/ana.10100
37 https://doi.org/10.1002/ana.410210513
38 https://doi.org/10.1002/ana.410310402
39 https://doi.org/10.1002/glia.1112
40 https://doi.org/10.1016/0923-2516(91)90051-4
41 https://doi.org/10.1016/0923-2516(91)90054-7
42 https://doi.org/10.1016/s0079-6123(08)62595-9
43 https://doi.org/10.1016/s0165-5728(01)00496-9
44 https://doi.org/10.1046/j.1365-2990.2000.00243.x
45 https://doi.org/10.1084/jem.192.3.393
46 https://doi.org/10.1084/jem.193.8.905
47 https://doi.org/10.1086/344938
48 https://doi.org/10.1086/514113
49 https://doi.org/10.1093/infdis/168.4.818
50 https://doi.org/10.1093/jnen/61.1.85
51 https://doi.org/10.1097/00002030-200307250-00004
52 https://doi.org/10.1111/j.1699-0463.1989.tb00759.x
53 https://doi.org/10.1111/j.1750-3639.1991.tb00646.x
54 https://doi.org/10.1126/science.270.5239.1158
55 https://doi.org/10.1126/science.287.5453.602
56 https://doi.org/10.1128/jvi.75.23.11686-11699.2001
57 https://doi.org/10.1136/jcp.45.12.1084
58 https://doi.org/10.1300/j128v01n01_02
59 schema:datePublished 2004-09
60 schema:datePublishedReg 2004-09-01
61 schema:description T lymphocytes are found within brains infected with human immunodeficiency virus (HIV) or simian immunodeficiency virus (SIV) where they are a minor, but consistently identified, population. However, little analysis of their phenotypes has been done, and questions concerning whether or not they are viral antigen specific has not been thoroughly examined. We investigated the central nervous system (CNS) of SIV-infected rhesus macaques to identify T-lymphocyte subsets in relation to virus-infected cells and brain microvessels. We have found that a sensitive antigen-retrieval technique greatly enhanced immunohistochemical detection of CD4+ and CD8+ T lymphocytes in control studies. In encephalitic brains of SIV-infected monkeys with acquired immunodeficiency syndrome (AIDS), we found a significant accumulation of CD8+ T lymphocytes but little-to-no accumulation of CD4+ T lymphocytes. CD4+ cells, when detected, were mostly monocyte/macrophages closely associated with CNS vessels. Using a combination of in situ hybridization for SIV RNA, and immunohistochemistry for CD8+ T lymphocytes and/or Glut-1 for endothelial cells on brain microvessels, we found CD8+ T lymphocytes with an angiocentric distribution often adjacent to virus-infected cells. In the CNS of animals with SIV encephalitis, there was a trend of CD8+ T lymphocytes that were not directly juxtaposed with CNS vessels. These data suggest that in brains of SIV-infected monkeys and HIV-infected humans, CD8+ T lymphocytes traffic to and are retained in the CNS in an angiocentric and possibly antigen-specific manner.
62 schema:genre research_article
63 schema:inLanguage en
64 schema:isAccessibleForFree false
65 schema:isPartOf N2db5c4ada29a407ab71258765447bd54
66 N982ca02038fb41bea243e1d32dae630e
67 sg:journal.1114176
68 schema:name Identification of T lymphocytes in simian immunodeficiency virus encephalitis: Distribution of CD8+ T cells in association with central nervous system vessels and virus
69 schema:pagination 315-325
70 schema:productId N04787bf3f6e74d099ebff225b20b7fec
71 N63e691349fac487da48f254c56c421a4
72 Na66b156de875438894f1d2cb3a570b52
73 Ncf4e6a0f63cc452dae53ba35d45b0d70
74 Nd99d37b23894417780d5c26066f13b2f
75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027110755
76 https://doi.org/10.1080/13550280490505382
77 schema:sdDatePublished 2019-04-10T21:34
78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
79 schema:sdPublisher Nd59fdc0aa5c44a70bcfa41d09380ba0a
80 schema:url http://link.springer.com/10.1080/13550280490505382
81 sgo:license sg:explorer/license/
82 sgo:sdDataset articles
83 rdf:type schema:ScholarlyArticle
84 N0441c0f29132467f9df65969fa6e640b schema:name Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
85 rdf:type schema:Organization
86 N04787bf3f6e74d099ebff225b20b7fec schema:name doi
87 schema:value 10.1080/13550280490505382
88 rdf:type schema:PropertyValue
89 N0573dc05162848d1896d351d088d8e76 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Disease Models, Animal
91 rdf:type schema:DefinedTerm
92 N0a7a81c0a7384f30a3299f107044def6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Simian Acquired Immunodeficiency Syndrome
94 rdf:type schema:DefinedTerm
95 N0a816aac847c4741aaaf42bd0b1d862e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Central Nervous System
97 rdf:type schema:DefinedTerm
98 N16ed55eab66a454d8c19cf4238208caa schema:affiliation https://www.grid.ac/institutes/grid.265219.b
99 schema:familyName Veasey
100 schema:givenName Ronald S.
101 rdf:type schema:Person
102 N2db5c4ada29a407ab71258765447bd54 schema:issueNumber 5
103 rdf:type schema:PublicationIssue
104 N331a99fc95b74bc289754b989c4a531a rdf:first sg:person.01121357756.45
105 rdf:rest Na5633d98deea4d2eabc4aa09b0b7967e
106 N3ca4faac22cb4f7a8faae53502e4c04c schema:name Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
107 Division of Viral Pathogenesis, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
108 rdf:type schema:Organization
109 N3dfdfb76501b4e4cad7e28574784b81b rdf:first N16ed55eab66a454d8c19cf4238208caa
110 rdf:rest Ndafd6b05de5945b09900fea9439af241
111 N5d17e3b9e4fb4bc8945688da19a3b2fd rdf:first sg:person.0615357007.65
112 rdf:rest N331a99fc95b74bc289754b989c4a531a
113 N63e691349fac487da48f254c56c421a4 schema:name dimensions_id
114 schema:value pub.1027110755
115 rdf:type schema:PropertyValue
116 N6fa2134c14a44cb4938fa11b4e048b79 schema:name Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
117 rdf:type schema:Organization
118 N7acbdf897468475c9056ed644e13deac schema:affiliation Nfa033f4eee9b4c6a9ce4020381231b56
119 schema:familyName Chesney
120 schema:givenName Gillian
121 rdf:type schema:Person
122 N80db3300578245e5886ae10fe66c699d schema:name Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
123 rdf:type schema:Organization
124 N8bdc7698243045a880c264609a8bcc8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Animals
126 rdf:type schema:DefinedTerm
127 N8e044e4e197748f7b42d7e861e93a5d8 rdf:first sg:person.01342420117.42
128 rdf:rest Nce4cc265e5b44d6baea176acfbfc1c85
129 N982ca02038fb41bea243e1d32dae630e schema:volumeNumber 10
130 rdf:type schema:PublicationVolume
131 N9969199de9d14b7ead5d7a4700422887 schema:name Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
132 rdf:type schema:Organization
133 Na011e15986d14f9dab0d450ced57947c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name CD8-Positive T-Lymphocytes
135 rdf:type schema:DefinedTerm
136 Na5633d98deea4d2eabc4aa09b0b7967e rdf:first sg:person.01106522134.30
137 rdf:rest N8e044e4e197748f7b42d7e861e93a5d8
138 Na66b156de875438894f1d2cb3a570b52 schema:name pubmed_id
139 schema:value 15385254
140 rdf:type schema:PropertyValue
141 Na9a281d875b441ab9e635e46d3b7294a rdf:first N7acbdf897468475c9056ed644e13deac
142 rdf:rest Ncb33a050a7224ed7b7d69924ad7faaed
143 Nbe792a25475540feb371e33c27f67522 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Macaca mulatta
145 rdf:type schema:DefinedTerm
146 Ncb33a050a7224ed7b7d69924ad7faaed rdf:first sg:person.014661040357.99
147 rdf:rest N5d17e3b9e4fb4bc8945688da19a3b2fd
148 Ncc3300afe8c14d60b1596baaa7b69542 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Simian Immunodeficiency Virus
150 rdf:type schema:DefinedTerm
151 Nce4cc265e5b44d6baea176acfbfc1c85 rdf:first sg:person.01211324340.32
152 rdf:rest N3dfdfb76501b4e4cad7e28574784b81b
153 Ncf4e6a0f63cc452dae53ba35d45b0d70 schema:name nlm_unique_id
154 schema:value 9508123
155 rdf:type schema:PropertyValue
156 Nd59fdc0aa5c44a70bcfa41d09380ba0a schema:name Springer Nature - SN SciGraph project
157 rdf:type schema:Organization
158 Nd99d37b23894417780d5c26066f13b2f schema:name readcube_id
159 schema:value 8125ae3f0b4c392b4ab6675e4386289449a2ed0a330471f08643510e725c0772
160 rdf:type schema:PropertyValue
161 Ndafd6b05de5945b09900fea9439af241 rdf:first sg:person.01350163345.19
162 rdf:rest rdf:nil
163 Nddb6ca80fa53425fbc0ee333efaca398 rdf:first sg:person.01112443667.03
164 rdf:rest Nfbf3a100761e41b3b7fef9c388b3a351
165 Nfa033f4eee9b4c6a9ce4020381231b56 schema:name Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
166 rdf:type schema:Organization
167 Nfbf3a100761e41b3b7fef9c388b3a351 rdf:first sg:person.01233405734.58
168 rdf:rest Na9a281d875b441ab9e635e46d3b7294a
169 Nfec99d4b823e4edeb13f539867812192 schema:name Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
170 rdf:type schema:Organization
171 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
172 schema:name Medical and Health Sciences
173 rdf:type schema:DefinedTerm
174 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
175 schema:name Immunology
176 rdf:type schema:DefinedTerm
177 sg:grant.2421695 http://pending.schema.org/fundedItem sg:pub.10.1080/13550280490505382
178 rdf:type schema:MonetaryGrant
179 sg:grant.2441136 http://pending.schema.org/fundedItem sg:pub.10.1080/13550280490505382
180 rdf:type schema:MonetaryGrant
181 sg:grant.2455307 http://pending.schema.org/fundedItem sg:pub.10.1080/13550280490505382
182 rdf:type schema:MonetaryGrant
183 sg:grant.2558380 http://pending.schema.org/fundedItem sg:pub.10.1080/13550280490505382
184 rdf:type schema:MonetaryGrant
185 sg:grant.2558802 http://pending.schema.org/fundedItem sg:pub.10.1080/13550280490505382
186 rdf:type schema:MonetaryGrant
187 sg:grant.2559492 http://pending.schema.org/fundedItem sg:pub.10.1080/13550280490505382
188 rdf:type schema:MonetaryGrant
189 sg:grant.2559753 http://pending.schema.org/fundedItem sg:pub.10.1080/13550280490505382
190 rdf:type schema:MonetaryGrant
191 sg:grant.2668027 http://pending.schema.org/fundedItem sg:pub.10.1080/13550280490505382
192 rdf:type schema:MonetaryGrant
193 sg:grant.2685813 http://pending.schema.org/fundedItem sg:pub.10.1080/13550280490505382
194 rdf:type schema:MonetaryGrant
195 sg:journal.1114176 schema:issn 1355-0284
196 1538-2443
197 schema:name Journal of NeuroVirology
198 rdf:type schema:Periodical
199 sg:person.01106522134.30 schema:affiliation N6fa2134c14a44cb4938fa11b4e048b79
200 schema:familyName Letvin
201 schema:givenName Norman L.
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106522134.30
203 rdf:type schema:Person
204 sg:person.01112443667.03 schema:affiliation N80db3300578245e5886ae10fe66c699d
205 schema:familyName Kim
206 schema:givenName Woong-Ki
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112443667.03
208 rdf:type schema:Person
209 sg:person.01121357756.45 schema:affiliation N9969199de9d14b7ead5d7a4700422887
210 schema:familyName Wüthrich
211 schema:givenName Christian
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01121357756.45
213 rdf:type schema:Person
214 sg:person.01211324340.32 schema:affiliation https://www.grid.ac/institutes/grid.265219.b
215 schema:familyName Lackner
216 schema:givenName Andrew
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01211324340.32
218 rdf:type schema:Person
219 sg:person.01233405734.58 schema:affiliation Nfec99d4b823e4edeb13f539867812192
220 schema:familyName Corey
221 schema:givenName Sarah
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233405734.58
223 rdf:type schema:Person
224 sg:person.01342420117.42 schema:affiliation N3ca4faac22cb4f7a8faae53502e4c04c
225 schema:familyName Koralnik
226 schema:givenName Igor J.
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342420117.42
228 rdf:type schema:Person
229 sg:person.01350163345.19 schema:affiliation N0441c0f29132467f9df65969fa6e640b
230 schema:familyName Williams
231 schema:givenName Kenneth
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350163345.19
233 rdf:type schema:Person
234 sg:person.014661040357.99 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
235 schema:familyName Knight
236 schema:givenName Heather
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014661040357.99
238 rdf:type schema:Person
239 sg:person.0615357007.65 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
240 schema:familyName Klumpp
241 schema:givenName Sherry
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615357007.65
243 rdf:type schema:Person
244 sg:pub.10.1007/978-3-642-78536-8_3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010531101
245 https://doi.org/10.1007/978-3-642-78536-8_3
246 rdf:type schema:CreativeWork
247 sg:pub.10.1007/bf00334676 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032055063
248 https://doi.org/10.1007/bf00334676
249 rdf:type schema:CreativeWork
250 sg:pub.10.1007/s00401-004-0852-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005521510
251 https://doi.org/10.1007/s00401-004-0852-0
252 rdf:type schema:CreativeWork
253 sg:pub.10.1038/335178a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045579829
254 https://doi.org/10.1038/335178a0
255 rdf:type schema:CreativeWork
256 sg:pub.10.1038/35073667 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018601522
257 https://doi.org/10.1038/35073667
258 rdf:type schema:CreativeWork
259 sg:pub.10.1080/135502801753248114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021871650
260 https://doi.org/10.1080/135502801753248114
261 rdf:type schema:CreativeWork
262 sg:pub.10.1080/13550280390173391 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009172020
263 https://doi.org/10.1080/13550280390173391
264 rdf:type schema:CreativeWork
265 sg:pub.10.3109/13550289609146909 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070985960
266 https://doi.org/10.3109/13550289609146909
267 rdf:type schema:CreativeWork
268 sg:pub.10.3109/13550289909015809 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070986088
269 https://doi.org/10.3109/13550289909015809
270 rdf:type schema:CreativeWork
271 https://app.dimensions.ai/details/publication/pub.1075537751 schema:CreativeWork
272 https://app.dimensions.ai/details/publication/pub.1076050174 schema:CreativeWork
273 https://app.dimensions.ai/details/publication/pub.1077335728 schema:CreativeWork
274 https://app.dimensions.ai/details/publication/pub.1077418599 schema:CreativeWork
275 https://app.dimensions.ai/details/publication/pub.1077658579 schema:CreativeWork
276 https://app.dimensions.ai/details/publication/pub.1077895593 schema:CreativeWork
277 https://app.dimensions.ai/details/publication/pub.1079357348 schema:CreativeWork
278 https://app.dimensions.ai/details/publication/pub.1079815105 schema:CreativeWork
279 https://app.dimensions.ai/details/publication/pub.1082483449 schema:CreativeWork
280 https://app.dimensions.ai/details/publication/pub.1082795355 schema:CreativeWork
281 https://app.dimensions.ai/details/publication/pub.1082826578 schema:CreativeWork
282 https://app.dimensions.ai/details/publication/pub.1083031253 schema:CreativeWork
283 https://app.dimensions.ai/details/publication/pub.1083252200 schema:CreativeWork
284 https://app.dimensions.ai/details/publication/pub.1083277713 schema:CreativeWork
285 https://app.dimensions.ai/details/publication/pub.1083345406 schema:CreativeWork
286 https://app.dimensions.ai/details/publication/pub.1083370005 schema:CreativeWork
287 https://doi.org/10.1002/ana.10100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049209854
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1002/ana.410210513 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017093329
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1002/ana.410310402 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038858368
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1002/glia.1112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035598387
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1016/0923-2516(91)90051-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037735855
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1016/0923-2516(91)90054-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006990514
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1016/s0079-6123(08)62595-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018585135
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1016/s0165-5728(01)00496-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050377172
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1046/j.1365-2990.2000.00243.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1041516324
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1084/jem.192.3.393 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047369678
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1084/jem.193.8.905 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041224337
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1086/344938 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033525713
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1086/514113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013274661
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1093/infdis/168.4.818 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059704090
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1093/jnen/61.1.85 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050567138
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1097/00002030-200307250-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030296893
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1111/j.1699-0463.1989.tb00759.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033797084
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1111/j.1750-3639.1991.tb00646.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1031998832
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1126/science.270.5239.1158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062551632
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1126/science.287.5453.602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062568160
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1128/jvi.75.23.11686-11699.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032928630
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1136/jcp.45.12.1084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040866707
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1300/j128v01n01_02 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041565014
332 rdf:type schema:CreativeWork
333 https://www.grid.ac/institutes/grid.265219.b schema:alternateName Tulane University
334 schema:name Tulane Regional Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana, USA
335 rdf:type schema:Organization
336 https://www.grid.ac/institutes/grid.38142.3c schema:alternateName Harvard University
337 schema:name Department of Comparative Pathology, Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts, USA
338 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...