Don’t Know What You’ve Got ’Til It’s Gone: Evidence in Stem Cell Experiments View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2013

AUTHORS

Melinda Bonnie Fagan

ABSTRACT

As Chapter 2 showed, exemplary methods for identifying stem cells share a basic structure of three stages (Figure 3.1). The starting point is a multicellular organism — the source of cells. From this source, cells are extracted and the values of some of their characters measured. These cells (or a sample thereof) are then manipulated so as to realize capacities for self-renewal and differentiation. Each experiment involves two manipulations. In the first, cells are removed from their original organismal context and placed in a new environment in which their traits can be measured. In the second, measured cells are transferred to yet a third environmental context, which allows stem cell capacities to be realized. Finally, the amount of self-renewal and differentiation is measured. Stem cell experiments43 thus consist of two manipulations, each followed by measurements. The objects manipulated are cells from some organismal source. More... »

PAGES

48-69

Book

TITLE

Philosophy of Stem Cell Biology

ISBN

978-1-349-34985-2
978-1-137-29602-3

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1057/9781137296023_3

DOI

http://dx.doi.org/10.1057/9781137296023_3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026790579


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