Smoking as a risk factor for end-stage renal failure in men with primary renal disease View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1998-09

AUTHORS

S R Orth, A Stöckmann, C Conradt, E Ritz, M Ferro, W Kreusser, G Piccoli, M Rambausek, D Roccatello, K Schäfer, H G Sieberth, C Wanner, B Watschinger, P Zucchelli

ABSTRACT

BACKGROUND: It is not known whether smoking increases the risk of end-stage renal failure (ESRF) in patients with primary renal disease. METHODS: We performed a retrospective multicenter case-control study including 582 patients from nine centers in Germany, Italy and Austria. The diseases investigated were IgA glomerulonephritis (IgA-GN) as a model of inflammatory renal disease and autosomal dominant polycystic kidney disease (ADPKD) as a model of non-inflammatory renal disease. Cases were patients who had progressed to ESRF and controls were patients who were not in ESRF, that is, whose serum-creatinine failed to progress to >3 mg/dl during the observation period and who did not require renal replacement therapy. Matching for renal disease (IgA-GN, ADPKD), gender, age at renal death and region of residence resulted in 102 individually matched pairs (IgA-GN N = 54, ADPKD N = 48). Multiple conditional logistic regression was used to estimate adjusted odds ratios for independent tobacco effects. RESULTS: In men (matched pairs: IgA-GN N = 44, ADPKD N = 28), a significant dose-dependent increase of the risk to progress to ESRF was found (non-adjusted). The baseline risk was defined as <5 pack-years (PY): (i) 5 to 15 PY, odds ratio 3.5 (95% CI 1.3 to 9.6), P = 0.017; (ii) >15 PY = 5.8 (2.0 to 17), P = 0.001. Systolic blood pressure, ACE inhibitor treatment and age at diagnosis emerged as potential confounders. After adjustment, the risk for ESRF in men with >5 PY was highly increased for patients without ACE inhibitor treatment [10.1 (2.3 to 45), P = 0.002] but not with ACE inhibitor treatment [1.4 (0.3 to 7.1), P = 0.65]. CONCLUSION: Smoking increases the risk of ESRF in men with inflammatory and non-inflammatory renal disease. More... »

PAGES

926-931

References to SciGraph publications

  • 1997-06. The renal risks of smoking in KIDNEY INTERNATIONAL
  • 1995-05. The global tobacco epidemic. in SCIENTIFIC AMERICAN
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1046/j.1523-1755.1998.00067.x

    DOI

    http://dx.doi.org/10.1046/j.1523-1755.1998.00067.x

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1002660559

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/9734618


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Case-Control Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Kidney Diseases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Kidney Failure, Chronic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Regression Analysis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Retrospective Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Risk Factors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Smoking", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Heidelberg University", 
              "id": "https://www.grid.ac/institutes/grid.7700.0", 
              "name": [
                "Department of Internal Medicine and Institute for Medical Biometry, Ruperto Carola University Heidelberg, Germany."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Orth", 
            "givenName": "S R", 
            "id": "sg:person.0732653473.12", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732653473.12"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "St\u00f6ckmann", 
            "givenName": "A", 
            "type": "Person"
          }, 
          {
            "familyName": "Conradt", 
            "givenName": "C", 
            "type": "Person"
          }, 
          {
            "familyName": "Ritz", 
            "givenName": "E", 
            "id": "sg:person.01152777576.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152777576.10"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Ferro", 
            "givenName": "M", 
            "id": "sg:person.0716730037.97", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716730037.97"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Kreusser", 
            "givenName": "W", 
            "id": "sg:person.01223744211.21", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223744211.21"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Piccoli", 
            "givenName": "G", 
            "id": "sg:person.013317565442.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013317565442.18"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Rambausek", 
            "givenName": "M", 
            "id": "sg:person.0733452055.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733452055.07"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Roccatello", 
            "givenName": "D", 
            "id": "sg:person.01267141235.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267141235.42"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Sch\u00e4fer", 
            "givenName": "K", 
            "type": "Person"
          }, 
          {
            "familyName": "Sieberth", 
            "givenName": "H G", 
            "id": "sg:person.01114467666.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114467666.31"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Wanner", 
            "givenName": "C", 
            "id": "sg:person.01114340530.04", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114340530.04"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Watschinger", 
            "givenName": "B", 
            "type": "Person"
          }, 
          {
            "familyName": "Zucchelli", 
            "givenName": "P", 
            "id": "sg:person.01304674335.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304674335.18"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1056/nejm199404073301406", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001571227"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2796.1990.tb00204.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003686104"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2796.1990.tb00204.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003686104"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.1991.03460170080037", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009100587"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejm199601043340103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010771024"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ki.1997.232", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011561693", 
              "https://doi.org/10.1038/ki.1997.232"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/08037059409102291", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015352228"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.ph.57.030195.001403", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016633243"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0272-6386(95)90119-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023678356"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejm199604113341502", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027755123"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0002-9343(85)90396-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028526216"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.1991.03460050068022", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029266558"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejm199403313301307", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037902654"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00004872-199205000-00014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039856545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00004872-199205000-00014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039856545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archinte.1992.00400220098017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045790553"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1464-5491.1994.tb00283.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046287374"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1464-5491.1994.tb00283.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046287374"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0002-8703(86)90645-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051756028"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archinte.152.10.2082", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054113549"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.265.17.2226", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054152552"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.265.5.614", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054152874"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/scientificamerican0595-44", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056542453", 
              "https://doi.org/10.1038/scientificamerican0595-44"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/diacare.17.2.126", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1070746285"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7326/0003-4819-123-10-199511150-00003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1073699673"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082554408", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082811798", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1998-09", 
        "datePublishedReg": "1998-09-01", 
        "description": "BACKGROUND: It is not known whether smoking increases the risk of end-stage renal failure (ESRF) in patients with primary renal disease.\nMETHODS: We performed a retrospective multicenter case-control study including 582 patients from nine centers in Germany, Italy and Austria. The diseases investigated were IgA glomerulonephritis (IgA-GN) as a model of inflammatory renal disease and autosomal dominant polycystic kidney disease (ADPKD) as a model of non-inflammatory renal disease. Cases were patients who had progressed to ESRF and controls were patients who were not in ESRF, that is, whose serum-creatinine failed to progress to >3 mg/dl during the observation period and who did not require renal replacement therapy. Matching for renal disease (IgA-GN, ADPKD), gender, age at renal death and region of residence resulted in 102 individually matched pairs (IgA-GN N = 54, ADPKD N = 48). Multiple conditional logistic regression was used to estimate adjusted odds ratios for independent tobacco effects.\nRESULTS: In men (matched pairs: IgA-GN N = 44, ADPKD N = 28), a significant dose-dependent increase of the risk to progress to ESRF was found (non-adjusted). The baseline risk was defined as <5 pack-years (PY): (i) 5 to 15 PY, odds ratio 3.5 (95% CI 1.3 to 9.6), P = 0.017; (ii) >15 PY = 5.8 (2.0 to 17), P = 0.001. Systolic blood pressure, ACE inhibitor treatment and age at diagnosis emerged as potential confounders. After adjustment, the risk for ESRF in men with >5 PY was highly increased for patients without ACE inhibitor treatment [10.1 (2.3 to 45), P = 0.002] but not with ACE inhibitor treatment [1.4 (0.3 to 7.1), P = 0.65].\nCONCLUSION: Smoking increases the risk of ESRF in men with inflammatory and non-inflammatory renal disease.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1046/j.1523-1755.1998.00067.x", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1015319", 
            "issn": [
              "0085-2538", 
              "1523-1755"
            ], 
            "name": "Kidney International", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "3", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "54"
          }
        ], 
        "name": "Smoking as a risk factor for end-stage renal failure in men with primary renal disease", 
        "pagination": "926-931", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "0caaf3124beda78f0471c73d2209357cdcb5658f5ceb440bfd9d6b9d39d0a4be"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "9734618"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "0323470"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1046/j.1523-1755.1998.00067.x"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1002660559"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1046/j.1523-1755.1998.00067.x", 
          "https://app.dimensions.ai/details/publication/pub.1002660559"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T20:56", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000579.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://www.nature.com/ki/journal/v54/n3/full/4490321a.html"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1046/j.1523-1755.1998.00067.x'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1046/j.1523-1755.1998.00067.x'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1046/j.1523-1755.1998.00067.x'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1046/j.1523-1755.1998.00067.x'


     

    This table displays all metadata directly associated to this object as RDF triples.

    267 TRIPLES      21 PREDICATES      66 URIs      34 LITERALS      22 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1046/j.1523-1755.1998.00067.x schema:about N108393d67527456b9fa257c037e24dea
    2 N2f1077d99ec84995b7e3c67af18c53a5
    3 N45504e7beaed473ba99ace56235bfc87
    4 N4ac2abca2d5f434c919b6f9b35e22479
    5 N4e44dd9f01e241859d2a2b6fc6790d0d
    6 N5d5a2b3530a2453cb5d95d4abd1ae0b1
    7 N73348e351c0d4a33940f3411ac2b7b08
    8 N7829c99a8ce64e8e8ddd353f44fc43f3
    9 N817e4e5c5f9c4b9480f79148afcea195
    10 N97ba9a0fee51478e86bcba8d3d0f800e
    11 Nc5480d12d2164954bffa2f6ffc0db793
    12 Ncfb9577d2435422d9694326f300d0396
    13 Nf115a65f3d364960982a33c98685b856
    14 anzsrc-for:11
    15 anzsrc-for:1103
    16 schema:author N96f6bccc27b247448acf4162afdbe35f
    17 schema:citation sg:pub.10.1038/ki.1997.232
    18 sg:pub.10.1038/scientificamerican0595-44
    19 https://app.dimensions.ai/details/publication/pub.1082554408
    20 https://app.dimensions.ai/details/publication/pub.1082811798
    21 https://doi.org/10.1001/archinte.152.10.2082
    22 https://doi.org/10.1001/archinte.1992.00400220098017
    23 https://doi.org/10.1001/jama.1991.03460050068022
    24 https://doi.org/10.1001/jama.1991.03460170080037
    25 https://doi.org/10.1001/jama.265.17.2226
    26 https://doi.org/10.1001/jama.265.5.614
    27 https://doi.org/10.1016/0002-8703(86)90645-9
    28 https://doi.org/10.1016/0002-9343(85)90396-1
    29 https://doi.org/10.1016/0272-6386(95)90119-1
    30 https://doi.org/10.1056/nejm199403313301307
    31 https://doi.org/10.1056/nejm199404073301406
    32 https://doi.org/10.1056/nejm199601043340103
    33 https://doi.org/10.1056/nejm199604113341502
    34 https://doi.org/10.1097/00004872-199205000-00014
    35 https://doi.org/10.1111/j.1365-2796.1990.tb00204.x
    36 https://doi.org/10.1111/j.1464-5491.1994.tb00283.x
    37 https://doi.org/10.1146/annurev.ph.57.030195.001403
    38 https://doi.org/10.2337/diacare.17.2.126
    39 https://doi.org/10.3109/08037059409102291
    40 https://doi.org/10.7326/0003-4819-123-10-199511150-00003
    41 schema:datePublished 1998-09
    42 schema:datePublishedReg 1998-09-01
    43 schema:description BACKGROUND: It is not known whether smoking increases the risk of end-stage renal failure (ESRF) in patients with primary renal disease. METHODS: We performed a retrospective multicenter case-control study including 582 patients from nine centers in Germany, Italy and Austria. The diseases investigated were IgA glomerulonephritis (IgA-GN) as a model of inflammatory renal disease and autosomal dominant polycystic kidney disease (ADPKD) as a model of non-inflammatory renal disease. Cases were patients who had progressed to ESRF and controls were patients who were not in ESRF, that is, whose serum-creatinine failed to progress to >3 mg/dl during the observation period and who did not require renal replacement therapy. Matching for renal disease (IgA-GN, ADPKD), gender, age at renal death and region of residence resulted in 102 individually matched pairs (IgA-GN N = 54, ADPKD N = 48). Multiple conditional logistic regression was used to estimate adjusted odds ratios for independent tobacco effects. RESULTS: In men (matched pairs: IgA-GN N = 44, ADPKD N = 28), a significant dose-dependent increase of the risk to progress to ESRF was found (non-adjusted). The baseline risk was defined as <5 pack-years (PY): (i) 5 to 15 PY, odds ratio 3.5 (95% CI 1.3 to 9.6), P = 0.017; (ii) >15 PY = 5.8 (2.0 to 17), P = 0.001. Systolic blood pressure, ACE inhibitor treatment and age at diagnosis emerged as potential confounders. After adjustment, the risk for ESRF in men with >5 PY was highly increased for patients without ACE inhibitor treatment [10.1 (2.3 to 45), P = 0.002] but not with ACE inhibitor treatment [1.4 (0.3 to 7.1), P = 0.65]. CONCLUSION: Smoking increases the risk of ESRF in men with inflammatory and non-inflammatory renal disease.
    44 schema:genre research_article
    45 schema:inLanguage en
    46 schema:isAccessibleForFree true
    47 schema:isPartOf N2126dcbe659e4c5a963d03e94d74a622
    48 Ne8f07a2037f3421cad61bd4dcf8e22f9
    49 sg:journal.1015319
    50 schema:name Smoking as a risk factor for end-stage renal failure in men with primary renal disease
    51 schema:pagination 926-931
    52 schema:productId N18fc5a7f73e44742af63b2b04ac401ad
    53 N8c12750ffccb4a29988d71e1c5c5ca1f
    54 N94f9e47e59aa4170b4e707f419847f40
    55 N9f06bdd8f75743bca21a4935d13be175
    56 Ncaad09fa5454480d849805b43044cfe4
    57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002660559
    58 https://doi.org/10.1046/j.1523-1755.1998.00067.x
    59 schema:sdDatePublished 2019-04-10T20:56
    60 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    61 schema:sdPublisher Na5225a4a7ef24c5a9e6efb4d12fa468f
    62 schema:url http://www.nature.com/ki/journal/v54/n3/full/4490321a.html
    63 sgo:license sg:explorer/license/
    64 sgo:sdDataset articles
    65 rdf:type schema:ScholarlyArticle
    66 N108393d67527456b9fa257c037e24dea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    67 schema:name Kidney Diseases
    68 rdf:type schema:DefinedTerm
    69 N18fc5a7f73e44742af63b2b04ac401ad schema:name doi
    70 schema:value 10.1046/j.1523-1755.1998.00067.x
    71 rdf:type schema:PropertyValue
    72 N1d92c9c534a2499e988cd043f1c21985 rdf:first sg:person.01114340530.04
    73 rdf:rest N7a2c97dd1c6942ffa5bf019328b189c9
    74 N2126dcbe659e4c5a963d03e94d74a622 schema:volumeNumber 54
    75 rdf:type schema:PublicationVolume
    76 N28cf52f1fbef4d5a8a230023e087502f rdf:first sg:person.01152777576.10
    77 rdf:rest Ncb0fd0027857429a9c183130496a5819
    78 N2f1077d99ec84995b7e3c67af18c53a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    79 schema:name Regression Analysis
    80 rdf:type schema:DefinedTerm
    81 N45504e7beaed473ba99ace56235bfc87 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    82 schema:name Aged
    83 rdf:type schema:DefinedTerm
    84 N4ac2abca2d5f434c919b6f9b35e22479 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    85 schema:name Retrospective Studies
    86 rdf:type schema:DefinedTerm
    87 N4e44dd9f01e241859d2a2b6fc6790d0d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    88 schema:name Kidney Failure, Chronic
    89 rdf:type schema:DefinedTerm
    90 N5d5a2b3530a2453cb5d95d4abd1ae0b1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    91 schema:name Male
    92 rdf:type schema:DefinedTerm
    93 N5d866f1c8abd4823b202911c9e10ce63 rdf:first sg:person.013317565442.18
    94 rdf:rest Nd119434f560943bbbec5dc9af3db4fa8
    95 N672efa323105480386f83879dce9f5f2 rdf:first sg:person.01223744211.21
    96 rdf:rest N5d866f1c8abd4823b202911c9e10ce63
    97 N6a8bf2f6ac6d409f94cc4676690da707 rdf:first N97d9ff1b4558456dad9efa8209c8f662
    98 rdf:rest Ne190cd6a80be428e80e4588c31bd8c33
    99 N6b06c3bf63df4e43a300dcd4ff1c77de rdf:first sg:person.01304674335.18
    100 rdf:rest rdf:nil
    101 N73348e351c0d4a33940f3411ac2b7b08 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    102 schema:name Risk Factors
    103 rdf:type schema:DefinedTerm
    104 N744a6a94f21a4ac0bb80e7a71795e3dd rdf:first Nd85b21c990d143999bbadb5c56d24069
    105 rdf:rest N28cf52f1fbef4d5a8a230023e087502f
    106 N7829c99a8ce64e8e8ddd353f44fc43f3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    107 schema:name Middle Aged
    108 rdf:type schema:DefinedTerm
    109 N7a2c97dd1c6942ffa5bf019328b189c9 rdf:first N7a4f15d90bce4cad8cc380ad215f97c3
    110 rdf:rest N6b06c3bf63df4e43a300dcd4ff1c77de
    111 N7a4f15d90bce4cad8cc380ad215f97c3 schema:familyName Watschinger
    112 schema:givenName B
    113 rdf:type schema:Person
    114 N817e4e5c5f9c4b9480f79148afcea195 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    115 schema:name Case-Control Studies
    116 rdf:type schema:DefinedTerm
    117 N8c12750ffccb4a29988d71e1c5c5ca1f schema:name readcube_id
    118 schema:value 0caaf3124beda78f0471c73d2209357cdcb5658f5ceb440bfd9d6b9d39d0a4be
    119 rdf:type schema:PropertyValue
    120 N9083ab27dc2b47bab13d1bfce9fe3614 rdf:first Na6d9f17abbb44f44907d9110676b74fc
    121 rdf:rest N744a6a94f21a4ac0bb80e7a71795e3dd
    122 N94f9e47e59aa4170b4e707f419847f40 schema:name pubmed_id
    123 schema:value 9734618
    124 rdf:type schema:PropertyValue
    125 N96f6bccc27b247448acf4162afdbe35f rdf:first sg:person.0732653473.12
    126 rdf:rest N9083ab27dc2b47bab13d1bfce9fe3614
    127 N97ba9a0fee51478e86bcba8d3d0f800e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    128 schema:name Smoking
    129 rdf:type schema:DefinedTerm
    130 N97d9ff1b4558456dad9efa8209c8f662 schema:familyName Schäfer
    131 schema:givenName K
    132 rdf:type schema:Person
    133 N9f06bdd8f75743bca21a4935d13be175 schema:name dimensions_id
    134 schema:value pub.1002660559
    135 rdf:type schema:PropertyValue
    136 Na5225a4a7ef24c5a9e6efb4d12fa468f schema:name Springer Nature - SN SciGraph project
    137 rdf:type schema:Organization
    138 Na6d9f17abbb44f44907d9110676b74fc schema:familyName Stöckmann
    139 schema:givenName A
    140 rdf:type schema:Person
    141 Nb4d696c9c4c144aabd2bc16b30c0d333 rdf:first sg:person.01267141235.42
    142 rdf:rest N6a8bf2f6ac6d409f94cc4676690da707
    143 Nc5480d12d2164954bffa2f6ffc0db793 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    144 schema:name Female
    145 rdf:type schema:DefinedTerm
    146 Ncaad09fa5454480d849805b43044cfe4 schema:name nlm_unique_id
    147 schema:value 0323470
    148 rdf:type schema:PropertyValue
    149 Ncb0fd0027857429a9c183130496a5819 rdf:first sg:person.0716730037.97
    150 rdf:rest N672efa323105480386f83879dce9f5f2
    151 Ncfb9577d2435422d9694326f300d0396 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    152 schema:name Humans
    153 rdf:type schema:DefinedTerm
    154 Nd119434f560943bbbec5dc9af3db4fa8 rdf:first sg:person.0733452055.07
    155 rdf:rest Nb4d696c9c4c144aabd2bc16b30c0d333
    156 Nd85b21c990d143999bbadb5c56d24069 schema:familyName Conradt
    157 schema:givenName C
    158 rdf:type schema:Person
    159 Ne190cd6a80be428e80e4588c31bd8c33 rdf:first sg:person.01114467666.31
    160 rdf:rest N1d92c9c534a2499e988cd043f1c21985
    161 Ne8f07a2037f3421cad61bd4dcf8e22f9 schema:issueNumber 3
    162 rdf:type schema:PublicationIssue
    163 Nf115a65f3d364960982a33c98685b856 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    164 schema:name Adult
    165 rdf:type schema:DefinedTerm
    166 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    167 schema:name Medical and Health Sciences
    168 rdf:type schema:DefinedTerm
    169 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    170 schema:name Clinical Sciences
    171 rdf:type schema:DefinedTerm
    172 sg:journal.1015319 schema:issn 0085-2538
    173 1523-1755
    174 schema:name Kidney International
    175 rdf:type schema:Periodical
    176 sg:person.01114340530.04 schema:familyName Wanner
    177 schema:givenName C
    178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114340530.04
    179 rdf:type schema:Person
    180 sg:person.01114467666.31 schema:familyName Sieberth
    181 schema:givenName H G
    182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114467666.31
    183 rdf:type schema:Person
    184 sg:person.01152777576.10 schema:familyName Ritz
    185 schema:givenName E
    186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152777576.10
    187 rdf:type schema:Person
    188 sg:person.01223744211.21 schema:familyName Kreusser
    189 schema:givenName W
    190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223744211.21
    191 rdf:type schema:Person
    192 sg:person.01267141235.42 schema:familyName Roccatello
    193 schema:givenName D
    194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267141235.42
    195 rdf:type schema:Person
    196 sg:person.01304674335.18 schema:familyName Zucchelli
    197 schema:givenName P
    198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304674335.18
    199 rdf:type schema:Person
    200 sg:person.013317565442.18 schema:familyName Piccoli
    201 schema:givenName G
    202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013317565442.18
    203 rdf:type schema:Person
    204 sg:person.0716730037.97 schema:familyName Ferro
    205 schema:givenName M
    206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716730037.97
    207 rdf:type schema:Person
    208 sg:person.0732653473.12 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
    209 schema:familyName Orth
    210 schema:givenName S R
    211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0732653473.12
    212 rdf:type schema:Person
    213 sg:person.0733452055.07 schema:familyName Rambausek
    214 schema:givenName M
    215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733452055.07
    216 rdf:type schema:Person
    217 sg:pub.10.1038/ki.1997.232 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011561693
    218 https://doi.org/10.1038/ki.1997.232
    219 rdf:type schema:CreativeWork
    220 sg:pub.10.1038/scientificamerican0595-44 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056542453
    221 https://doi.org/10.1038/scientificamerican0595-44
    222 rdf:type schema:CreativeWork
    223 https://app.dimensions.ai/details/publication/pub.1082554408 schema:CreativeWork
    224 https://app.dimensions.ai/details/publication/pub.1082811798 schema:CreativeWork
    225 https://doi.org/10.1001/archinte.152.10.2082 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054113549
    226 rdf:type schema:CreativeWork
    227 https://doi.org/10.1001/archinte.1992.00400220098017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045790553
    228 rdf:type schema:CreativeWork
    229 https://doi.org/10.1001/jama.1991.03460050068022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029266558
    230 rdf:type schema:CreativeWork
    231 https://doi.org/10.1001/jama.1991.03460170080037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009100587
    232 rdf:type schema:CreativeWork
    233 https://doi.org/10.1001/jama.265.17.2226 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054152552
    234 rdf:type schema:CreativeWork
    235 https://doi.org/10.1001/jama.265.5.614 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054152874
    236 rdf:type schema:CreativeWork
    237 https://doi.org/10.1016/0002-8703(86)90645-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051756028
    238 rdf:type schema:CreativeWork
    239 https://doi.org/10.1016/0002-9343(85)90396-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028526216
    240 rdf:type schema:CreativeWork
    241 https://doi.org/10.1016/0272-6386(95)90119-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023678356
    242 rdf:type schema:CreativeWork
    243 https://doi.org/10.1056/nejm199403313301307 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037902654
    244 rdf:type schema:CreativeWork
    245 https://doi.org/10.1056/nejm199404073301406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001571227
    246 rdf:type schema:CreativeWork
    247 https://doi.org/10.1056/nejm199601043340103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010771024
    248 rdf:type schema:CreativeWork
    249 https://doi.org/10.1056/nejm199604113341502 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027755123
    250 rdf:type schema:CreativeWork
    251 https://doi.org/10.1097/00004872-199205000-00014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039856545
    252 rdf:type schema:CreativeWork
    253 https://doi.org/10.1111/j.1365-2796.1990.tb00204.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1003686104
    254 rdf:type schema:CreativeWork
    255 https://doi.org/10.1111/j.1464-5491.1994.tb00283.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1046287374
    256 rdf:type schema:CreativeWork
    257 https://doi.org/10.1146/annurev.ph.57.030195.001403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016633243
    258 rdf:type schema:CreativeWork
    259 https://doi.org/10.2337/diacare.17.2.126 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070746285
    260 rdf:type schema:CreativeWork
    261 https://doi.org/10.3109/08037059409102291 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015352228
    262 rdf:type schema:CreativeWork
    263 https://doi.org/10.7326/0003-4819-123-10-199511150-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073699673
    264 rdf:type schema:CreativeWork
    265 https://www.grid.ac/institutes/grid.7700.0 schema:alternateName Heidelberg University
    266 schema:name Department of Internal Medicine and Institute for Medical Biometry, Ruperto Carola University Heidelberg, Germany.
    267 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...