Testicular sperm extraction using microdissection for non-obstructive azoospermia View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2002-03

AUTHORS

Hatsuki Hibi, Tomohiro Taki, Yoshiaki Yamada, Nobuaki Honda, Hidetoshi Fukatsu, Masanori Yamamoto, Yoshimasa Asada

ABSTRACT

Background : Men presenting with non-obstructive azoospermia (NOA) caused by germinal failure can now be treated in some cases using testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI). However, TESE is a blind procedure that does not identify the focal sperm-producing areas until excision of the testicular tissue. Microdissection TESE, which is the only method available for obtaining excised dilated seminiferous tubules under the operating microscope, improves sperm yield with minimal tissue excision in NOA patients. Methods and Results : We performed this procedure on 16 NOA patients. All subjects underwent a microdissection TESE on the right testis, and triple biopsy on the left testis in consecutive fashion in order to compare the efficacy of microdissection TESE with that of a standard biopsy. Although dilated seminiferous tubules were presented in all patients, spermatozoa were retrieved in only a single patient by microdissection TESE. Furthermore, spermatozoa could not be identified by standard biopsies. Conclusion : In this series, microdissection TESE did not contribute to spermatozoa recovery in NOA patients. Further study is needed in order to arrive at a reliable assessment of microdissection TESE relative to a standard multiple biopsy in cases of NOA. (Reprod Med Biol 2002; 1: 31-34). More... »

PAGES

31-34

Identifiers

URI

http://scigraph.springernature.com/pub.10.1046/j.1445-5781.2002.00006.x

DOI

http://dx.doi.org/10.1046/j.1445-5781.2002.00006.x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012369646

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29699070


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