Isolation and characterization of monoclonal antibodies directed against murine FRP-1/CD98/4F2 heavy chain: Murine FRP-1 is an alloantigen and amino acid ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1999-02

AUTHORS

Hideki Tsumura, Mitsuo Kawano, Masanori Tajima, Takashi Kusaura, Yuuji Kozuka, Satoshi Yoshimura, Hiroshi Komada, Masato Tsurudome, Machiko Nishio, Shigeru Kusagawa, Keishirou Shimura, Yasuhiko Ito

ABSTRACT

Nineteen mAb directed against murine fusion regulatory protein-1 (mFRP-1)/4F2/CD98 were isolated and their biological properties were analysed. Intriguingly, mFRP-1 was found to be an alloantigen, namely, FRP-1.1 (DBA/2 and CBA mice type) and FRP-1.2 (BALB/c, C57BL/6 and C3H/He mice type). The nucleotide sequences of FRP-1.1 and FRP-1.2 were determined, demonstrating that amino acid change at 129 (P<-->R) is related to the alloantigenicity. mFRP-1 is expressed on thymocytes, on spleen cells, on peripheral lymphocytes and on blood monocytes, suggesting that the physiological role in vivo of murine FRP-1 is different from that of human FRP-1. The biological activities of antimFRP-1 mAbs showed by the present study are: (i) enhancement of Newcastle disease virus-induced cell fusion; (ii) suppression of HIVgp160-mediated cell fusion; and (iii) induction of aggregation and multinucleated giant cells of monocytes/macrophages. More... »

PAGES

19

Identifiers

URI

http://scigraph.springernature.com/pub.10.1046/j.1440-1711.1999.00792.x

DOI

http://dx.doi.org/10.1046/j.1440-1711.1999.00792.x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044475111

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10101682


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Substitution", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antibodies, Monoclonal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens, CD", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Base Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carrier Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Aggregation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Fusion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Primers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fusion Regulatory Protein-1", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Giant Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HIV Envelope Protein gp160", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Isoantigens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred BALB C", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred C3H", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred C57BL", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred CBA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred DBA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Newcastle disease virus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Homology, Amino Acid", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan", 
            "Institute of Laboratory Animals, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tsumura", 
        "givenName": "Hideki", 
        "id": "sg:person.01261425554.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261425554.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kawano", 
        "givenName": "Mitsuo", 
        "id": "sg:person.0575661451.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575661451.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tajima", 
        "givenName": "Masanori", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kusaura", 
        "givenName": "Takashi", 
        "id": "sg:person.01017620223.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017620223.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kozuka", 
        "givenName": "Yuuji", 
        "id": "sg:person.016072012464.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016072012464.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yoshimura", 
        "givenName": "Satoshi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Komada", 
        "givenName": "Hiroshi", 
        "id": "sg:person.01201730223.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01201730223.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tsurudome", 
        "givenName": "Masato", 
        "id": "sg:person.01175307354.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175307354.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishio", 
        "givenName": "Machiko", 
        "id": "sg:person.01303237474.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01303237474.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kusagawa", 
        "givenName": "Shigeru", 
        "id": "sg:person.0721302674.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721302674.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Institute of Laboratory Animals, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shimura", 
        "givenName": "Keishirou", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mie University", 
          "id": "https://www.grid.ac/institutes/grid.260026.0", 
          "name": [
            "Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ito", 
        "givenName": "Yasuhiko", 
        "id": "sg:person.01115752560.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115752560.71"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1073/pnas.84.24.9204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000067531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2736(96)00125-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006185563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0008-8749(91)90395-r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006759285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj3120863", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008634715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj3120863", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008634715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/36349", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013249508", 
          "https://doi.org/10.1038/36349"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1359/jbmr.1998.13.1.44", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013652407"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.89.12.5596", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016314477"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.84.18.6526", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021190420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.8.9.3809", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021664010"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/17.5.1915", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025992651"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.8.1.466", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033678313"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/1523-1747.ep12263581", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035708242", 
          "https://doi.org/10.1111/1523-1747.ep12263581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/0022-1317-77-11-2747", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060359841"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/0022-1317-78-1-83", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060360196"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076871000", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077171379", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078803701", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078806633", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079507396", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079518093", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080009602", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080049996", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081728491", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081855684", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082213774", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082413237", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082491091", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082646546", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1994.tb06479.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082692750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082879393", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1999-02", 
    "datePublishedReg": "1999-02-01", 
    "description": "Nineteen mAb directed against murine fusion regulatory protein-1 (mFRP-1)/4F2/CD98 were isolated and their biological properties were analysed. Intriguingly, mFRP-1 was found to be an alloantigen, namely, FRP-1.1 (DBA/2 and CBA mice type) and FRP-1.2 (BALB/c, C57BL/6 and C3H/He mice type). The nucleotide sequences of FRP-1.1 and FRP-1.2 were determined, demonstrating that amino acid change at 129 (P<-->R) is related to the alloantigenicity. mFRP-1 is expressed on thymocytes, on spleen cells, on peripheral lymphocytes and on blood monocytes, suggesting that the physiological role in vivo of murine FRP-1 is different from that of human FRP-1. The biological activities of antimFRP-1 mAbs showed by the present study are: (i) enhancement of Newcastle disease virus-induced cell fusion; (ii) suppression of HIVgp160-mediated cell fusion; and (iii) induction of aggregation and multinucleated giant cells of monocytes/macrophages.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1046/j.1440-1711.1999.00792.x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1019561", 
        "issn": [
          "0818-9641", 
          "1440-1711"
        ], 
        "name": "Immunology and Cell Biology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "77"
      }
    ], 
    "name": "Isolation and characterization of monoclonal antibodies directed against murine FRP-1/CD98/4F2 heavy chain: Murine FRP-1 is an alloantigen and amino acid change at 129 (P\u2190\u2192R) is related to the alloantigenicity", 
    "pagination": "19", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "d3da0603c242e573c6f0ade0d4ffdff5e38d33b10e9dc8b9e09577df48337ee2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "10101682"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8706300"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1046/j.1440-1711.1999.00792.x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1044475111"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1046/j.1440-1711.1999.00792.x", 
      "https://app.dimensions.ai/details/publication/pub.1044475111"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T00:59", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000475.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/icb19993"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1046/j.1440-1711.1999.00792.x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1046/j.1440-1711.1999.00792.x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1046/j.1440-1711.1999.00792.x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1046/j.1440-1711.1999.00792.x'


 

This table displays all metadata directly associated to this object as RDF triples.

321 TRIPLES      21 PREDICATES      84 URIs      46 LITERALS      34 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1046/j.1440-1711.1999.00792.x schema:about N053fe5d2fb7f4ef3ae51b2b28a113953
2 N05f91b5e32d44b5f9f0c2a2dc233faf6
3 N0bbff928bb4c4ce0947bd332f481edc5
4 N11edf6b476824acfadf51ca9ce025529
5 N220699b0e4554a68a2d649946bc86c29
6 N22315f8150ab4635a464d486302bad1f
7 N246fe06d75984bd4b3939f1c75aa1ab5
8 N32a6e782a47a493facc112e6c8e5f62b
9 N3916dd3b19b8421d841f45250808ae6d
10 N4033a09563114fc4828e650030838a75
11 N644e2ff43f5a4326a1703dacbd3527a5
12 N69cff1f7416c46ca9f9d5bbce3229b9c
13 N7b8acfb71f9a428e918417ceb1081fa8
14 N7f5a7e38d53845b4a9203e31ae55218a
15 N85bc3b6616ef4c639e5eaf379428ad07
16 N9628814a7d164a4fb4088fe33d8452df
17 N983d47357e9644e7bab72ccae3147f45
18 Na08335c3d13a480d8fed67c5fabf0c8b
19 Na45ca75782c34e88b5d1f2630a1a4a0d
20 Naa1b16e3d881412c8f51148e347c9936
21 Nade11eb2d8a9488aa33150f36185bec4
22 Naf1f4e80a3b14efaa88fed25095ca63d
23 Nc8624e68bdfd423b9484dd51c42bdc3b
24 Ne54d95e1de504aceb245cf58afa6838b
25 Nf6593284f9234192b4f6dbf6815b6c5d
26 anzsrc-for:06
27 anzsrc-for:0601
28 schema:author Nb94cea55d3b54e7caab4fb277234db9a
29 schema:citation sg:pub.10.1038/36349
30 sg:pub.10.1111/1523-1747.ep12263581
31 https://app.dimensions.ai/details/publication/pub.1076871000
32 https://app.dimensions.ai/details/publication/pub.1077171379
33 https://app.dimensions.ai/details/publication/pub.1078803701
34 https://app.dimensions.ai/details/publication/pub.1078806633
35 https://app.dimensions.ai/details/publication/pub.1079507396
36 https://app.dimensions.ai/details/publication/pub.1079518093
37 https://app.dimensions.ai/details/publication/pub.1080009602
38 https://app.dimensions.ai/details/publication/pub.1080049996
39 https://app.dimensions.ai/details/publication/pub.1081728491
40 https://app.dimensions.ai/details/publication/pub.1081855684
41 https://app.dimensions.ai/details/publication/pub.1082213774
42 https://app.dimensions.ai/details/publication/pub.1082413237
43 https://app.dimensions.ai/details/publication/pub.1082491091
44 https://app.dimensions.ai/details/publication/pub.1082646546
45 https://app.dimensions.ai/details/publication/pub.1082879393
46 https://doi.org/10.1002/j.1460-2075.1994.tb06479.x
47 https://doi.org/10.1016/0005-2736(96)00125-3
48 https://doi.org/10.1016/0008-8749(91)90395-r
49 https://doi.org/10.1042/bj3120863
50 https://doi.org/10.1073/pnas.84.18.6526
51 https://doi.org/10.1073/pnas.84.24.9204
52 https://doi.org/10.1073/pnas.89.12.5596
53 https://doi.org/10.1093/nar/17.5.1915
54 https://doi.org/10.1099/0022-1317-77-11-2747
55 https://doi.org/10.1099/0022-1317-78-1-83
56 https://doi.org/10.1128/mcb.8.1.466
57 https://doi.org/10.1128/mcb.8.9.3809
58 https://doi.org/10.1359/jbmr.1998.13.1.44
59 schema:datePublished 1999-02
60 schema:datePublishedReg 1999-02-01
61 schema:description Nineteen mAb directed against murine fusion regulatory protein-1 (mFRP-1)/4F2/CD98 were isolated and their biological properties were analysed. Intriguingly, mFRP-1 was found to be an alloantigen, namely, FRP-1.1 (DBA/2 and CBA mice type) and FRP-1.2 (BALB/c, C57BL/6 and C3H/He mice type). The nucleotide sequences of FRP-1.1 and FRP-1.2 were determined, demonstrating that amino acid change at 129 (P<-->R) is related to the alloantigenicity. mFRP-1 is expressed on thymocytes, on spleen cells, on peripheral lymphocytes and on blood monocytes, suggesting that the physiological role in vivo of murine FRP-1 is different from that of human FRP-1. The biological activities of antimFRP-1 mAbs showed by the present study are: (i) enhancement of Newcastle disease virus-induced cell fusion; (ii) suppression of HIVgp160-mediated cell fusion; and (iii) induction of aggregation and multinucleated giant cells of monocytes/macrophages.
62 schema:genre research_article
63 schema:inLanguage en
64 schema:isAccessibleForFree true
65 schema:isPartOf N7aa0d82d67044d45b78a6c8323111e99
66 Neeb64dc930ea435f9be6e7d6b7747e75
67 sg:journal.1019561
68 schema:name Isolation and characterization of monoclonal antibodies directed against murine FRP-1/CD98/4F2 heavy chain: Murine FRP-1 is an alloantigen and amino acid change at 129 (P←→R) is related to the alloantigenicity
69 schema:pagination 19
70 schema:productId N096d9d8a277a4726910438744f0b3eb3
71 N346a2cf6f2b4418da65443fb2e35e1ee
72 Nb8a7f10b88b94c24b6e0960dd26246af
73 Nda766177121a494687e65417ed6d9e5d
74 Ndcf491f67a8f4d2082f7d642fbecc641
75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044475111
76 https://doi.org/10.1046/j.1440-1711.1999.00792.x
77 schema:sdDatePublished 2019-04-11T00:59
78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
79 schema:sdPublisher N37f2d6ac042b456e908f4cce4921d5f6
80 schema:url https://www.nature.com/articles/icb19993
81 sgo:license sg:explorer/license/
82 sgo:sdDataset articles
83 rdf:type schema:ScholarlyArticle
84 N053fe5d2fb7f4ef3ae51b2b28a113953 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Mice, Inbred C3H
86 rdf:type schema:DefinedTerm
87 N05f91b5e32d44b5f9f0c2a2dc233faf6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Animals
89 rdf:type schema:DefinedTerm
90 N096d9d8a277a4726910438744f0b3eb3 schema:name readcube_id
91 schema:value d3da0603c242e573c6f0ade0d4ffdff5e38d33b10e9dc8b9e09577df48337ee2
92 rdf:type schema:PropertyValue
93 N0bbff928bb4c4ce0947bd332f481edc5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Antigens, CD
95 rdf:type schema:DefinedTerm
96 N11edf6b476824acfadf51ca9ce025529 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Cell Aggregation
98 rdf:type schema:DefinedTerm
99 N15fd7d12335e4cb8ba20c7ca7acf8e16 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
100 schema:familyName Tajima
101 schema:givenName Masanori
102 rdf:type schema:Person
103 N220699b0e4554a68a2d649946bc86c29 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Amino Acid Sequence
105 rdf:type schema:DefinedTerm
106 N22315f8150ab4635a464d486302bad1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Mice, Inbred DBA
108 rdf:type schema:DefinedTerm
109 N246fe06d75984bd4b3939f1c75aa1ab5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Sequence Homology, Amino Acid
111 rdf:type schema:DefinedTerm
112 N25c7e628f18a4698b83e80e48bdd1b7f rdf:first sg:person.01201730223.51
113 rdf:rest N9053ae11460a42c386e86d49f985e34e
114 N32a6e782a47a493facc112e6c8e5f62b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Newcastle disease virus
116 rdf:type schema:DefinedTerm
117 N346a2cf6f2b4418da65443fb2e35e1ee schema:name doi
118 schema:value 10.1046/j.1440-1711.1999.00792.x
119 rdf:type schema:PropertyValue
120 N37f2d6ac042b456e908f4cce4921d5f6 schema:name Springer Nature - SN SciGraph project
121 rdf:type schema:Organization
122 N3916dd3b19b8421d841f45250808ae6d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Amino Acid Substitution
124 rdf:type schema:DefinedTerm
125 N3ef948ddf04e43cdbeded6693ace2096 rdf:first sg:person.0721302674.78
126 rdf:rest N6720fc2cfc634b7bafca7a2b81b4c9db
127 N4033a09563114fc4828e650030838a75 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Antibodies, Monoclonal
129 rdf:type schema:DefinedTerm
130 N44d01b84be1b4f44bc64de4fb8b38544 rdf:first sg:person.01017620223.86
131 rdf:rest N6a8ca7d5caf84836adb1f4ef9b6364af
132 N557cfce430c447cf88ddf51834e87d59 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
133 schema:familyName Yoshimura
134 schema:givenName Satoshi
135 rdf:type schema:Person
136 N644e2ff43f5a4326a1703dacbd3527a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Base Sequence
138 rdf:type schema:DefinedTerm
139 N6720fc2cfc634b7bafca7a2b81b4c9db rdf:first N6794cc95ab5a45e2a30a8459a6c2763f
140 rdf:rest N8c5e7978c7bc4792ad1b2fa12a7d5a28
141 N6794cc95ab5a45e2a30a8459a6c2763f schema:affiliation https://www.grid.ac/institutes/grid.260026.0
142 schema:familyName Shimura
143 schema:givenName Keishirou
144 rdf:type schema:Person
145 N69cff1f7416c46ca9f9d5bbce3229b9c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Cell Line
147 rdf:type schema:DefinedTerm
148 N6a8ca7d5caf84836adb1f4ef9b6364af rdf:first sg:person.016072012464.58
149 rdf:rest Nae18733e567d4cf9b1feb6a79e7b7c38
150 N7aa0d82d67044d45b78a6c8323111e99 schema:volumeNumber 77
151 rdf:type schema:PublicationVolume
152 N7b8acfb71f9a428e918417ceb1081fa8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Fusion Regulatory Protein-1
154 rdf:type schema:DefinedTerm
155 N7f5a7e38d53845b4a9203e31ae55218a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Mice, Inbred CBA
157 rdf:type schema:DefinedTerm
158 N85bc3b6616ef4c639e5eaf379428ad07 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name DNA Primers
160 rdf:type schema:DefinedTerm
161 N8c5e7978c7bc4792ad1b2fa12a7d5a28 rdf:first sg:person.01115752560.71
162 rdf:rest rdf:nil
163 N9053ae11460a42c386e86d49f985e34e rdf:first sg:person.01175307354.73
164 rdf:rest Nb5ecda69c12c4b51a73ad2799ad59cb6
165 N9628814a7d164a4fb4088fe33d8452df schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name Mice, Inbred BALB C
167 rdf:type schema:DefinedTerm
168 N983d47357e9644e7bab72ccae3147f45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Isoantigens
170 rdf:type schema:DefinedTerm
171 Na08335c3d13a480d8fed67c5fabf0c8b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Mice, Inbred C57BL
173 rdf:type schema:DefinedTerm
174 Na45ca75782c34e88b5d1f2630a1a4a0d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Mice
176 rdf:type schema:DefinedTerm
177 Naa1b16e3d881412c8f51148e347c9936 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Carrier Proteins
179 rdf:type schema:DefinedTerm
180 Nade11eb2d8a9488aa33150f36185bec4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Humans
182 rdf:type schema:DefinedTerm
183 Nae18733e567d4cf9b1feb6a79e7b7c38 rdf:first N557cfce430c447cf88ddf51834e87d59
184 rdf:rest N25c7e628f18a4698b83e80e48bdd1b7f
185 Naf1f4e80a3b14efaa88fed25095ca63d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Molecular Sequence Data
187 rdf:type schema:DefinedTerm
188 Nb5ecda69c12c4b51a73ad2799ad59cb6 rdf:first sg:person.01303237474.61
189 rdf:rest N3ef948ddf04e43cdbeded6693ace2096
190 Nb8a7f10b88b94c24b6e0960dd26246af schema:name pubmed_id
191 schema:value 10101682
192 rdf:type schema:PropertyValue
193 Nb94cea55d3b54e7caab4fb277234db9a rdf:first sg:person.01261425554.20
194 rdf:rest Nf8cb3dc8a89a43dfa88bbbc3050b2806
195 Nc8624e68bdfd423b9484dd51c42bdc3b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
196 schema:name HIV Envelope Protein gp160
197 rdf:type schema:DefinedTerm
198 Nda766177121a494687e65417ed6d9e5d schema:name nlm_unique_id
199 schema:value 8706300
200 rdf:type schema:PropertyValue
201 Ndcf491f67a8f4d2082f7d642fbecc641 schema:name dimensions_id
202 schema:value pub.1044475111
203 rdf:type schema:PropertyValue
204 Ne41f5d5ec71c4781a0cf0287e537335b rdf:first N15fd7d12335e4cb8ba20c7ca7acf8e16
205 rdf:rest N44d01b84be1b4f44bc64de4fb8b38544
206 Ne54d95e1de504aceb245cf58afa6838b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
207 schema:name Cell Fusion
208 rdf:type schema:DefinedTerm
209 Neeb64dc930ea435f9be6e7d6b7747e75 schema:issueNumber 1
210 rdf:type schema:PublicationIssue
211 Nf6593284f9234192b4f6dbf6815b6c5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
212 schema:name Giant Cells
213 rdf:type schema:DefinedTerm
214 Nf8cb3dc8a89a43dfa88bbbc3050b2806 rdf:first sg:person.0575661451.03
215 rdf:rest Ne41f5d5ec71c4781a0cf0287e537335b
216 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
217 schema:name Biological Sciences
218 rdf:type schema:DefinedTerm
219 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
220 schema:name Biochemistry and Cell Biology
221 rdf:type schema:DefinedTerm
222 sg:journal.1019561 schema:issn 0818-9641
223 1440-1711
224 schema:name Immunology and Cell Biology
225 rdf:type schema:Periodical
226 sg:person.01017620223.86 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
227 schema:familyName Kusaura
228 schema:givenName Takashi
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017620223.86
230 rdf:type schema:Person
231 sg:person.01115752560.71 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
232 schema:familyName Ito
233 schema:givenName Yasuhiko
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115752560.71
235 rdf:type schema:Person
236 sg:person.01175307354.73 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
237 schema:familyName Tsurudome
238 schema:givenName Masato
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175307354.73
240 rdf:type schema:Person
241 sg:person.01201730223.51 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
242 schema:familyName Komada
243 schema:givenName Hiroshi
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01201730223.51
245 rdf:type schema:Person
246 sg:person.01261425554.20 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
247 schema:familyName Tsumura
248 schema:givenName Hideki
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261425554.20
250 rdf:type schema:Person
251 sg:person.01303237474.61 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
252 schema:familyName Nishio
253 schema:givenName Machiko
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01303237474.61
255 rdf:type schema:Person
256 sg:person.016072012464.58 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
257 schema:familyName Kozuka
258 schema:givenName Yuuji
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016072012464.58
260 rdf:type schema:Person
261 sg:person.0575661451.03 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
262 schema:familyName Kawano
263 schema:givenName Mitsuo
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575661451.03
265 rdf:type schema:Person
266 sg:person.0721302674.78 schema:affiliation https://www.grid.ac/institutes/grid.260026.0
267 schema:familyName Kusagawa
268 schema:givenName Shigeru
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721302674.78
270 rdf:type schema:Person
271 sg:pub.10.1038/36349 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013249508
272 https://doi.org/10.1038/36349
273 rdf:type schema:CreativeWork
274 sg:pub.10.1111/1523-1747.ep12263581 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035708242
275 https://doi.org/10.1111/1523-1747.ep12263581
276 rdf:type schema:CreativeWork
277 https://app.dimensions.ai/details/publication/pub.1076871000 schema:CreativeWork
278 https://app.dimensions.ai/details/publication/pub.1077171379 schema:CreativeWork
279 https://app.dimensions.ai/details/publication/pub.1078803701 schema:CreativeWork
280 https://app.dimensions.ai/details/publication/pub.1078806633 schema:CreativeWork
281 https://app.dimensions.ai/details/publication/pub.1079507396 schema:CreativeWork
282 https://app.dimensions.ai/details/publication/pub.1079518093 schema:CreativeWork
283 https://app.dimensions.ai/details/publication/pub.1080009602 schema:CreativeWork
284 https://app.dimensions.ai/details/publication/pub.1080049996 schema:CreativeWork
285 https://app.dimensions.ai/details/publication/pub.1081728491 schema:CreativeWork
286 https://app.dimensions.ai/details/publication/pub.1081855684 schema:CreativeWork
287 https://app.dimensions.ai/details/publication/pub.1082213774 schema:CreativeWork
288 https://app.dimensions.ai/details/publication/pub.1082413237 schema:CreativeWork
289 https://app.dimensions.ai/details/publication/pub.1082491091 schema:CreativeWork
290 https://app.dimensions.ai/details/publication/pub.1082646546 schema:CreativeWork
291 https://app.dimensions.ai/details/publication/pub.1082879393 schema:CreativeWork
292 https://doi.org/10.1002/j.1460-2075.1994.tb06479.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1082692750
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1016/0005-2736(96)00125-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006185563
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1016/0008-8749(91)90395-r schema:sameAs https://app.dimensions.ai/details/publication/pub.1006759285
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1042/bj3120863 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008634715
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1073/pnas.84.18.6526 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021190420
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1073/pnas.84.24.9204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000067531
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1073/pnas.89.12.5596 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016314477
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1093/nar/17.5.1915 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025992651
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1099/0022-1317-77-11-2747 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060359841
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1099/0022-1317-78-1-83 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060360196
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1128/mcb.8.1.466 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033678313
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1128/mcb.8.9.3809 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021664010
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1359/jbmr.1998.13.1.44 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013652407
317 rdf:type schema:CreativeWork
318 https://www.grid.ac/institutes/grid.260026.0 schema:alternateName Mie University
319 schema:name Department of Microbiology, Mie University School of Medicine, Tsu, Mie-ken, Japan
320 Institute of Laboratory Animals, Mie University School of Medicine, Tsu, Mie-ken, Japan
321 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...