Glycerol and galactose substituted zinc phthalocyanines. Synthesis and photodynamic activity View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-01-14

AUTHORS

Yunus Zorlu, Mahmut Ali Ermeydan, Fabienne Dumoulin, Vefa Ahsen, Huguette Savoie, Ross W. Boyle

ABSTRACT

Three novel water soluble, non-ionic, zinc phthalocyanines (Pcs) have been synthesized and their spectroscopic and photodynamic properties investigated in aqueous media. One of the three compounds was shown to be significantly less aggregated, when compared to the other two compounds, and this effect was found to be related to both the nature of the substituent, and also the position at which it is attached to themacrocycle. Photodynamic activity and cellular uptake by human adenocarcinoma cells (HT-29) was shown to be linked to the aggregation state of the Pcs in water. More... »

PAGES

312-318

Identifiers

URI

http://scigraph.springernature.com/pub.10.1039/b817348f

DOI

http://dx.doi.org/10.1039/b817348f

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1014769969

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19255671


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