Sublethal pesticide doses negatively affect survival and the cellular responses in American foulbrood-infected honeybee larvae View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-02-01

AUTHORS

Javier Hernández López, Sophie Krainer, Antonia Engert, Wolfgang Schuehly, Ulrike Riessberger-Gallé, Karl Crailsheim

ABSTRACT

Disclosing interactions between pesticides and bee infections is of most interest to understand challenges that pollinators are facing and to which extent bee health is compromised. Here, we address the individual and combined effect that three different pesticides (dimethoate, clothianidin and fluvalinate) and an American foulbrood (AFB) infection have on mortality and the cellular immune response of honeybee larvae. We demonstrate for the first time a synergistic interaction when larvae are exposed to sublethal doses of dimethoate or clothianidin in combination with Paenibacillus larvae, the causative agent of AFB. A significantly higher mortality than the expected sum of the effects of each individual stressor was observed in co-exposed larvae, which was in parallel with a drastic reduction of the total and differential hemocyte counts. Our results underline that characterizing the cellular response of larvae to individual and combined stressors allows unmasking previously undetected sublethal effects of pesticides in colony health. More... »

PAGES

40853

References to SciGraph publications

  • 2005-04. Differences in drone and worker physiology in honeybees (Apis mellifera) in APIDOLOGIE
  • 2005-02-15. Comparative Sublethal Toxicity of Nine Pesticides on Olfactory Learning Performances of the Honeybee Apis mellifera in ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
  • 2015-12-07. Cellular immunity in Apis mellifera: studying hemocytes brings light about bees skills to confront threats in APIDOLOGIE
  • 2012-10-21. Combined pesticide exposure severely affects individual- and colony-level traits in bees in NATURE
  • 2015-04-22. Seed coating with a neonicotinoid insecticide negatively affects wild bees in NATURE
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  • 2012-10-16. Effects of immunostimulation on social behavior, chemical communication and genome-wide gene expression in honey bee workers (Apis mellifera) in BMC GENOMICS
  • 2012-02-18. Neonicotinoids in bees: a review on concentrations, side-effects and risk assessment in ECOTOXICOLOGY
  • 2007-11-17. Effects of Sublethal Doses of Acetamiprid and Thiamethoxam on the Behavior of the Honeybee (Apis mellifera) in ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
  • 1987. IMPAIRMENT OF A CLASSICAL CONDITIONED RESPONSE OF THE HONEY BEE (APIS MELLIFERA L.) BY SUBLETHAL DOSES OF SYNTHETIC PYRETHROID INSECTICIDES in APIDOLOGIE
  • 2014-09-23. Toxicity and biochemical changes in the honey bee Apis mellifera exposed to four insecticides under laboratory conditions in APIDOLOGIE
  • 2015-07-02. Detoxification mechanisms of honey bees (Apis mellifera) resulting in tolerance of dietary nicotine in SCIENTIFIC REPORTS
  • 2005-01. Modes of honeybees exposure to systemic insecticides: estimated amounts of contaminated pollen and nectar consumed by different categories of bees in APIDOLOGIE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/srep40853

    DOI

    http://dx.doi.org/10.1038/srep40853

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1083400824

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28145462


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