Lytic polysaccharide monooxygenases disrupt the cellulose fibers structure View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-12

AUTHORS

Ana Villares, Céline Moreau, Chloé Bennati-Granier, Sona Garajova, Loïc Foucat, Xavier Falourd, Bodo Saake, Jean-Guy Berrin, Bernard Cathala

ABSTRACT

Lytic polysaccharide monooxygenases (LPMOs) are a class of powerful oxidative enzymes that breakdown recalcitrant polysaccharides such as cellulose. Here we investigate the action of LPMOs on cellulose fibers. After enzymatic treatment and dispersion, LPMO-treated fibers show intense fibrillation. Cellulose structure modifications visualized at different scales indicate that LPMO creates nicking points that trigger the disintegration of the cellulose fibrillar structure with rupture of chains and release of elementary nanofibrils. Investigation of LPMO action using solid-state NMR provides direct evidence of modification of accessible and inaccessible surfaces surrounding the crystalline core of the fibrils. The chains breakage likely induces modifications of the cellulose network and weakens fibers cohesion promoting their disruption. Besides the formation of new initiation sites for conventional cellulases, this work provides the first evidence of the direct oxidative action of LPMOs with the mechanical weakening of the cellulose ultrastructure. LPMOs can be viewed as promising biocatalysts for enzymatic modification or degradation of cellulose fibers. More... »

PAGES

40262

References to SciGraph publications

  • 2016-12. Lytic polysaccharide monooxygenases from Myceliophthora thermophila C1 differ in substrate preference and reducing agent specificity in BIOTECHNOLOGY FOR BIOFUELS
  • 2014-12. Surface modification of cellulose microfibrils by periodate oxidation and subsequent reductive amination with benzylamine: a topochemical study in CELLULOSE
  • 2016-09. Single-domain flavoenzymes trigger lytic polysaccharide monooxygenases for oxidative degradation of cellulose in SCIENTIFIC REPORTS
  • 2015-12. Substrate specificity and regioselectivity of fungal AA9 lytic polysaccharide monooxygenases secreted by Podospora anserina in BIOTECHNOLOGY FOR BIOFUELS
  • 2016-12. Techno-economic evaluation of integrated first- and second-generation ethanol production from grain and straw in BIOTECHNOLOGY FOR BIOFUELS
  • 2015-01. Morphological properties of nanofibrillated cellulose produced using wet grinding as an ultimate fibrillation process in JOURNAL OF MATERIALS SCIENCE
  • 2015-12. Discovery of the combined oxidative cleavage of plant xylan and cellulose by a new fungal polysaccharide monooxygenase in BIOTECHNOLOGY FOR BIOFUELS
  • 2010-12. Morphological investigation of nanoparticles obtained from combined mechanical shearing, and enzymatic and acid hydrolysis of sisal fibers in CELLULOSE
  • 2013-12. Expansion of the enzymatic repertoire of the CAZy database to integrate auxiliary redox enzymes in BIOTECHNOLOGY FOR BIOFUELS
  • 2012-12. Novel enzymes for the degradation of cellulose in BIOTECHNOLOGY FOR BIOFUELS
  • 2015-12. Designer synthetic media for studying microbial-catalyzed biofuel production in BIOTECHNOLOGY FOR BIOFUELS
  • 2015-12. Mechanism, kinetics and microbiology of inhibition caused by long-chain fatty acids in anaerobic digestion of algal biomass in BIOTECHNOLOGY FOR BIOFUELS
  • 2016-11. Enzymatic cellulose oxidation is linked to lignin by long-range electron transfer in SCIENTIFIC REPORTS
  • 2016-02-29. The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases in NATURE CHEMICAL BIOLOGY
  • 2016-12. Salt-responsive lytic polysaccharide monooxygenases from the mangrove fungus Pestalotiopsis sp. NCi6 in BIOTECHNOLOGY FOR BIOFUELS
  • 2010-12. Automated assay for screening the enzymatic release of reducing sugars from micronized biomass in MICROBIAL CELL FACTORIES
  • 2000-03. A comparative CP/MAS 13C-NMR study of cellulose structure in spruce wood and kraft pulp in CELLULOSE
  • 2016-04-04. Light-driven oxidation of polysaccharides by photosynthetic pigments and a metalloenzyme in NATURE COMMUNICATIONS
  • 2014-12. Chemical and ultrastructural changes in cotton cellulose induced by laundering and textile use in CELLULOSE
  • 2015-06. Comparison testing of methods for gel permeation chromatography of cellulose: coming closer to a standard protocol in CELLULOSE
  • 2012-12. Production of four Neurospora crassa lytic polysaccharide monooxygenases in Pichia pastoris monitored by a fluorimetric assay in BIOTECHNOLOGY FOR BIOFUELS
  • 2001-06. The influence of hemicellulose on fibril aggregation of kraft pulp fibres as revealed by FE-SEM and CP/MAS 13C-NMR in CELLULOSE
  • 2012-12. A versatile toolkit for high throughput functional genomics with Trichoderma reesei in BIOTECHNOLOGY FOR BIOFUELS
  • 2016-12. Metagenomic analysis and functional characterization of the biogas microbiome using high throughput shotgun sequencing and a novel binning strategy in BIOTECHNOLOGY FOR BIOFUELS
  • 2015-12. Enhanced degradation of softwood versus hardwood by the white-rot fungus Pycnoporus coccineus in BIOTECHNOLOGY FOR BIOFUELS
  • 2015-12. Recombinant Expression of Trichoderma reesei Cel61A in Pichia pastoris: Optimizing Yield and N-terminal Processing in MOLECULAR BIOTECHNOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/srep40262

    DOI

    http://dx.doi.org/10.1038/srep40262

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1040674920

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28071716


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cellulose", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mixed Function Oxygenases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Polysaccharides", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Wood", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Centre Angers-Nantes Pays de la Loire", 
              "id": "https://www.grid.ac/institutes/grid.460203.3", 
              "name": [
                "BIA, INRA, 44300, Nantes, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Villares", 
            "givenName": "Ana", 
            "id": "sg:person.01245043055.29", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245043055.29"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Centre Angers-Nantes Pays de la Loire", 
              "id": "https://www.grid.ac/institutes/grid.460203.3", 
              "name": [
                "BIA, INRA, 44300, Nantes, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Moreau", 
            "givenName": "C\u00e9line", 
            "id": "sg:person.01322544341.74", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322544341.74"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Aix-Marseille University", 
              "id": "https://www.grid.ac/institutes/grid.5399.6", 
              "name": [
                "Biodiversit\u00e9 et Biotechnologie Fongiques, INRA, Aix Marseille Univ, UMR1163, 13009, Marseille, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bennati-Granier", 
            "givenName": "Chlo\u00e9", 
            "id": "sg:person.01124433452.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124433452.22"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Aix-Marseille University", 
              "id": "https://www.grid.ac/institutes/grid.5399.6", 
              "name": [
                "Biodiversit\u00e9 et Biotechnologie Fongiques, INRA, Aix Marseille Univ, UMR1163, 13009, Marseille, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Garajova", 
            "givenName": "Sona", 
            "id": "sg:person.0757666306.16", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757666306.16"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Centre Angers-Nantes Pays de la Loire", 
              "id": "https://www.grid.ac/institutes/grid.460203.3", 
              "name": [
                "BIA, INRA, 44300, Nantes, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Foucat", 
            "givenName": "Lo\u00efc", 
            "id": "sg:person.0631277530.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631277530.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Centre Angers-Nantes Pays de la Loire", 
              "id": "https://www.grid.ac/institutes/grid.460203.3", 
              "name": [
                "BIA, INRA, 44300, Nantes, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Falourd", 
            "givenName": "Xavier", 
            "id": "sg:person.0774114624.38", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0774114624.38"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Hamburg", 
              "id": "https://www.grid.ac/institutes/grid.9026.d", 
              "name": [
                "Chemical Wood Technology, University of Hamburg, Leuschnerstra\u00dfe 91b, 21031 Hamburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Saake", 
            "givenName": "Bodo", 
            "id": "sg:person.01222116675.46", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222116675.46"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Aix-Marseille University", 
              "id": "https://www.grid.ac/institutes/grid.5399.6", 
              "name": [
                "Biodiversit\u00e9 et Biotechnologie Fongiques, INRA, Aix Marseille Univ, UMR1163, 13009, Marseille, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Berrin", 
            "givenName": "Jean-Guy", 
            "id": "sg:person.01257430676.53", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257430676.53"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Centre Angers-Nantes Pays de la Loire", 
              "id": "https://www.grid.ac/institutes/grid.460203.3", 
              "name": [
                "BIA, INRA, 44300, Nantes, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cathala", 
            "givenName": "Bernard", 
            "id": "sg:person.0731231164.09", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731231164.09"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1073/pnas.1323629111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000091224"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m113.459396", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000763727"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1754-6834-6-41", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000812569", 
              "https://doi.org/10.1186/1754-6834-6-41"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-015-0423-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001820275", 
              "https://doi.org/10.1186/s13068-015-0423-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1754-6834-5-45", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002219986", 
              "https://doi.org/10.1186/1754-6834-5-45"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10570-014-0434-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003369640", 
              "https://doi.org/10.1007/s10570-014-0434-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10570-014-0434-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003369640", 
              "https://doi.org/10.1007/s10570-014-0434-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bm061215p", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003859239"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bm061215p", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003859239"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-016-0441-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003905845", 
              "https://doi.org/10.1186/s13068-016-0441-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/srep18561", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003928386", 
              "https://doi.org/10.1038/srep18561"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.carbpol.2006.01.034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004501249"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1016645809958", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004878902", 
              "https://doi.org/10.1023/a:1016645809958"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m113.530196", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005291541"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cbpa.2014.02.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008420546"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0144-8617(98)00021-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008737204"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-016-0594-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010975174", 
              "https://doi.org/10.1186/s13068-016-0594-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-016-0594-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010975174", 
              "https://doi.org/10.1186/s13068-016-0594-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.5936/csbj.201209019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011183943"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-016-0520-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013257726", 
              "https://doi.org/10.1186/s13068-016-0520-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10570-015-0586-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014618013", 
              "https://doi.org/10.1007/s10570-015-0586-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-015-0284-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015097541", 
              "https://doi.org/10.1186/s13068-015-0284-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1754-6834-5-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015338590", 
              "https://doi.org/10.1186/1754-6834-5-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1475-2859-9-58", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016783089", 
              "https://doi.org/10.1186/1475-2859-9-58"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12033-015-9887-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017273600", 
              "https://doi.org/10.1007/s12033-015-9887-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1179/1743280415y.0000000009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018007197"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev-biochem-060614-034439", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020232116"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10570-014-0459-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026694712", 
              "https://doi.org/10.1007/s10570-014-0459-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0108313", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027061480"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bm0509725", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028891651"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bm0509725", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028891651"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0008-6215(97)00130-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030840696"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0008-6215(98)00236-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031185336"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.eurpolymj.2007.05.038", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035046756"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-014-0179-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035594727", 
              "https://doi.org/10.1186/s13068-014-0179-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-014-0179-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035594727", 
              "https://doi.org/10.1186/s13068-014-0179-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10570-010-9449-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036083105", 
              "https://doi.org/10.1007/s10570-010-9449-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10570-010-9449-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036083105", 
              "https://doi.org/10.1007/s10570-010-9449-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nchembio.2029", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036828541", 
              "https://doi.org/10.1038/nchembio.2029"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tibtech.2015.09.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037667294"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/aem.02942-12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038177700"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1754-6834-5-79", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038416621", 
              "https://doi.org/10.1186/1754-6834-5-79"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1009236932134", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038980198", 
              "https://doi.org/10.1023/a:1009236932134"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-015-0407-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041990069", 
              "https://doi.org/10.1186/s13068-015-0407-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.str.2012.04.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043963361"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10853-014-8609-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046746581", 
              "https://doi.org/10.1007/s10853-014-8609-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-015-0274-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046809495", 
              "https://doi.org/10.1186/s13068-015-0274-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-015-0274-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046809495", 
              "https://doi.org/10.1186/s13068-015-0274-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.chroma.2012.11.048", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048414496"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1137016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049275105"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0926-2040(99)00043-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049590942"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13068-015-0322-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050098301", 
              "https://doi.org/10.1186/s13068-015-0322-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/masy.19920610117", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051664567"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/srep28276", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052311837", 
              "https://doi.org/10.1038/srep28276"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0027807", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052692031"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja409384b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053121664"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncomms11134", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053415325", 
              "https://doi.org/10.1038/ncomms11134"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bm0000337", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055219285"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bm0000337", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055219285"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/cb200351y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055226065"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja210657t", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055851526"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bst20150204", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056718004"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bst20150204", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056718004"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.aaf3165", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062667452"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2017-12", 
        "datePublishedReg": "2017-12-01", 
        "description": "Lytic polysaccharide monooxygenases (LPMOs) are a class of powerful oxidative enzymes that breakdown recalcitrant polysaccharides such as cellulose. Here we investigate the action of LPMOs on cellulose fibers. After enzymatic treatment and dispersion, LPMO-treated fibers show intense fibrillation. Cellulose structure modifications visualized at different scales indicate that LPMO creates nicking points that trigger the disintegration of the cellulose fibrillar structure with rupture of chains and release of elementary nanofibrils. Investigation of LPMO action using solid-state NMR provides direct evidence of modification of accessible and inaccessible surfaces surrounding the crystalline core of the fibrils. The chains breakage likely induces modifications of the cellulose network and weakens fibers cohesion promoting their disruption. Besides the formation of new initiation sites for conventional cellulases, this work provides the first evidence of the direct oxidative action of LPMOs with the mechanical weakening of the cellulose ultrastructure. LPMOs can be viewed as promising biocatalysts for enzymatic modification or degradation of cellulose fibers.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/srep40262", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1045337", 
            "issn": [
              "2045-2322"
            ], 
            "name": "Scientific Reports", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "7"
          }
        ], 
        "name": "Lytic polysaccharide monooxygenases disrupt the cellulose fibers structure", 
        "pagination": "40262", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "c1c275789f214b46c17a4b708d2712dda0c99268a921ae71ade96da01749620a"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "28071716"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101563288"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/srep40262"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1040674920"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/srep40262", 
          "https://app.dimensions.ai/details/publication/pub.1040674920"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T16:51", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000572.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://www.nature.com/articles/srep40262"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/srep40262'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/srep40262'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/srep40262'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/srep40262'


     

    This table displays all metadata directly associated to this object as RDF triples.

    337 TRIPLES      21 PREDICATES      88 URIs      25 LITERALS      13 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/srep40262 schema:about N44e6b94af2f84115a7fe21718340c3e2
    2 N9f4202efee3f4fda892be3e99ef34e4a
    3 Nb1d08acaa7dc45568de2681daca66a0e
    4 Nfd331e3d3740413baa3f839a775999d8
    5 anzsrc-for:06
    6 anzsrc-for:0601
    7 schema:author Nf4b56224d4ab4b749125a9098a446978
    8 schema:citation sg:pub.10.1007/s10570-010-9449-z
    9 sg:pub.10.1007/s10570-014-0434-9
    10 sg:pub.10.1007/s10570-014-0459-0
    11 sg:pub.10.1007/s10570-015-0586-2
    12 sg:pub.10.1007/s10853-014-8609-1
    13 sg:pub.10.1007/s12033-015-9887-9
    14 sg:pub.10.1023/a:1009236932134
    15 sg:pub.10.1023/a:1016645809958
    16 sg:pub.10.1038/nchembio.2029
    17 sg:pub.10.1038/ncomms11134
    18 sg:pub.10.1038/srep18561
    19 sg:pub.10.1038/srep28276
    20 sg:pub.10.1186/1475-2859-9-58
    21 sg:pub.10.1186/1754-6834-5-1
    22 sg:pub.10.1186/1754-6834-5-45
    23 sg:pub.10.1186/1754-6834-5-79
    24 sg:pub.10.1186/1754-6834-6-41
    25 sg:pub.10.1186/s13068-014-0179-6
    26 sg:pub.10.1186/s13068-015-0274-3
    27 sg:pub.10.1186/s13068-015-0284-1
    28 sg:pub.10.1186/s13068-015-0322-z
    29 sg:pub.10.1186/s13068-015-0407-8
    30 sg:pub.10.1186/s13068-015-0423-8
    31 sg:pub.10.1186/s13068-016-0441-1
    32 sg:pub.10.1186/s13068-016-0520-3
    33 sg:pub.10.1186/s13068-016-0594-y
    34 https://doi.org/10.1002/masy.19920610117
    35 https://doi.org/10.1016/j.carbpol.2006.01.034
    36 https://doi.org/10.1016/j.cbpa.2014.02.015
    37 https://doi.org/10.1016/j.chroma.2012.11.048
    38 https://doi.org/10.1016/j.eurpolymj.2007.05.038
    39 https://doi.org/10.1016/j.str.2012.04.002
    40 https://doi.org/10.1016/j.tibtech.2015.09.006
    41 https://doi.org/10.1016/s0008-6215(97)00130-4
    42 https://doi.org/10.1016/s0008-6215(98)00236-5
    43 https://doi.org/10.1016/s0144-8617(98)00021-6
    44 https://doi.org/10.1016/s0926-2040(99)00043-0
    45 https://doi.org/10.1021/bm0000337
    46 https://doi.org/10.1021/bm0509725
    47 https://doi.org/10.1021/bm061215p
    48 https://doi.org/10.1021/cb200351y
    49 https://doi.org/10.1021/ja210657t
    50 https://doi.org/10.1021/ja409384b
    51 https://doi.org/10.1042/bst20150204
    52 https://doi.org/10.1073/pnas.1323629111
    53 https://doi.org/10.1074/jbc.m113.459396
    54 https://doi.org/10.1074/jbc.m113.530196
    55 https://doi.org/10.1126/science.1137016
    56 https://doi.org/10.1126/science.aaf3165
    57 https://doi.org/10.1128/aem.02942-12
    58 https://doi.org/10.1146/annurev-biochem-060614-034439
    59 https://doi.org/10.1179/1743280415y.0000000009
    60 https://doi.org/10.1371/journal.pone.0027807
    61 https://doi.org/10.1371/journal.pone.0108313
    62 https://doi.org/10.5936/csbj.201209019
    63 schema:datePublished 2017-12
    64 schema:datePublishedReg 2017-12-01
    65 schema:description Lytic polysaccharide monooxygenases (LPMOs) are a class of powerful oxidative enzymes that breakdown recalcitrant polysaccharides such as cellulose. Here we investigate the action of LPMOs on cellulose fibers. After enzymatic treatment and dispersion, LPMO-treated fibers show intense fibrillation. Cellulose structure modifications visualized at different scales indicate that LPMO creates nicking points that trigger the disintegration of the cellulose fibrillar structure with rupture of chains and release of elementary nanofibrils. Investigation of LPMO action using solid-state NMR provides direct evidence of modification of accessible and inaccessible surfaces surrounding the crystalline core of the fibrils. The chains breakage likely induces modifications of the cellulose network and weakens fibers cohesion promoting their disruption. Besides the formation of new initiation sites for conventional cellulases, this work provides the first evidence of the direct oxidative action of LPMOs with the mechanical weakening of the cellulose ultrastructure. LPMOs can be viewed as promising biocatalysts for enzymatic modification or degradation of cellulose fibers.
    66 schema:genre research_article
    67 schema:inLanguage en
    68 schema:isAccessibleForFree true
    69 schema:isPartOf Nae5e4d63a7ae41689f671a537ea5f962
    70 Nf78d3e0340384672add01299aa4844a9
    71 sg:journal.1045337
    72 schema:name Lytic polysaccharide monooxygenases disrupt the cellulose fibers structure
    73 schema:pagination 40262
    74 schema:productId N0d2cae42fa374869a9fb4d1d62f14dab
    75 N7768e46c95ab448182c6935f8044f1a0
    76 N959487ccf2df44888e5fb44ca59f8f87
    77 Nac48478f9496400aa4db15d85fee8587
    78 Ndbbfbd1af7944d95a6853ef068400654
    79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040674920
    80 https://doi.org/10.1038/srep40262
    81 schema:sdDatePublished 2019-04-10T16:51
    82 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    83 schema:sdPublisher Nd822838b2dec4dc6a07ee17e682fff26
    84 schema:url http://www.nature.com/articles/srep40262
    85 sgo:license sg:explorer/license/
    86 sgo:sdDataset articles
    87 rdf:type schema:ScholarlyArticle
    88 N01ee3543694943bc9a73e069bad58aa9 rdf:first sg:person.0774114624.38
    89 rdf:rest N8c8a47cfd8484ca398090fc5a018998e
    90 N0d2cae42fa374869a9fb4d1d62f14dab schema:name dimensions_id
    91 schema:value pub.1040674920
    92 rdf:type schema:PropertyValue
    93 N1dc240328fdc48159774a84d7c04ba48 rdf:first sg:person.0631277530.02
    94 rdf:rest N01ee3543694943bc9a73e069bad58aa9
    95 N44e6b94af2f84115a7fe21718340c3e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    96 schema:name Polysaccharides
    97 rdf:type schema:DefinedTerm
    98 N7768e46c95ab448182c6935f8044f1a0 schema:name doi
    99 schema:value 10.1038/srep40262
    100 rdf:type schema:PropertyValue
    101 N838a36f7b02e47ca8914cebc284be2c7 rdf:first sg:person.01257430676.53
    102 rdf:rest Ndc1b20a9f5e647faa0ff426067c10c3c
    103 N8b00a269002e4e36b303b805e9faaa28 rdf:first sg:person.01322544341.74
    104 rdf:rest Nfbb6edd2bf864348a4309208e8e61d0b
    105 N8c8a47cfd8484ca398090fc5a018998e rdf:first sg:person.01222116675.46
    106 rdf:rest N838a36f7b02e47ca8914cebc284be2c7
    107 N959487ccf2df44888e5fb44ca59f8f87 schema:name nlm_unique_id
    108 schema:value 101563288
    109 rdf:type schema:PropertyValue
    110 N9f4202efee3f4fda892be3e99ef34e4a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    111 schema:name Cellulose
    112 rdf:type schema:DefinedTerm
    113 Nac48478f9496400aa4db15d85fee8587 schema:name readcube_id
    114 schema:value c1c275789f214b46c17a4b708d2712dda0c99268a921ae71ade96da01749620a
    115 rdf:type schema:PropertyValue
    116 Nae5e4d63a7ae41689f671a537ea5f962 schema:issueNumber 1
    117 rdf:type schema:PublicationIssue
    118 Nb1d08acaa7dc45568de2681daca66a0e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    119 schema:name Wood
    120 rdf:type schema:DefinedTerm
    121 Nc29cc0c80bd84194994b594599cc7bab rdf:first sg:person.0757666306.16
    122 rdf:rest N1dc240328fdc48159774a84d7c04ba48
    123 Nd822838b2dec4dc6a07ee17e682fff26 schema:name Springer Nature - SN SciGraph project
    124 rdf:type schema:Organization
    125 Ndbbfbd1af7944d95a6853ef068400654 schema:name pubmed_id
    126 schema:value 28071716
    127 rdf:type schema:PropertyValue
    128 Ndc1b20a9f5e647faa0ff426067c10c3c rdf:first sg:person.0731231164.09
    129 rdf:rest rdf:nil
    130 Nf4b56224d4ab4b749125a9098a446978 rdf:first sg:person.01245043055.29
    131 rdf:rest N8b00a269002e4e36b303b805e9faaa28
    132 Nf78d3e0340384672add01299aa4844a9 schema:volumeNumber 7
    133 rdf:type schema:PublicationVolume
    134 Nfbb6edd2bf864348a4309208e8e61d0b rdf:first sg:person.01124433452.22
    135 rdf:rest Nc29cc0c80bd84194994b594599cc7bab
    136 Nfd331e3d3740413baa3f839a775999d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    137 schema:name Mixed Function Oxygenases
    138 rdf:type schema:DefinedTerm
    139 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    140 schema:name Biological Sciences
    141 rdf:type schema:DefinedTerm
    142 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    143 schema:name Biochemistry and Cell Biology
    144 rdf:type schema:DefinedTerm
    145 sg:journal.1045337 schema:issn 2045-2322
    146 schema:name Scientific Reports
    147 rdf:type schema:Periodical
    148 sg:person.01124433452.22 schema:affiliation https://www.grid.ac/institutes/grid.5399.6
    149 schema:familyName Bennati-Granier
    150 schema:givenName Chloé
    151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124433452.22
    152 rdf:type schema:Person
    153 sg:person.01222116675.46 schema:affiliation https://www.grid.ac/institutes/grid.9026.d
    154 schema:familyName Saake
    155 schema:givenName Bodo
    156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222116675.46
    157 rdf:type schema:Person
    158 sg:person.01245043055.29 schema:affiliation https://www.grid.ac/institutes/grid.460203.3
    159 schema:familyName Villares
    160 schema:givenName Ana
    161 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245043055.29
    162 rdf:type schema:Person
    163 sg:person.01257430676.53 schema:affiliation https://www.grid.ac/institutes/grid.5399.6
    164 schema:familyName Berrin
    165 schema:givenName Jean-Guy
    166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257430676.53
    167 rdf:type schema:Person
    168 sg:person.01322544341.74 schema:affiliation https://www.grid.ac/institutes/grid.460203.3
    169 schema:familyName Moreau
    170 schema:givenName Céline
    171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322544341.74
    172 rdf:type schema:Person
    173 sg:person.0631277530.02 schema:affiliation https://www.grid.ac/institutes/grid.460203.3
    174 schema:familyName Foucat
    175 schema:givenName Loïc
    176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631277530.02
    177 rdf:type schema:Person
    178 sg:person.0731231164.09 schema:affiliation https://www.grid.ac/institutes/grid.460203.3
    179 schema:familyName Cathala
    180 schema:givenName Bernard
    181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731231164.09
    182 rdf:type schema:Person
    183 sg:person.0757666306.16 schema:affiliation https://www.grid.ac/institutes/grid.5399.6
    184 schema:familyName Garajova
    185 schema:givenName Sona
    186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757666306.16
    187 rdf:type schema:Person
    188 sg:person.0774114624.38 schema:affiliation https://www.grid.ac/institutes/grid.460203.3
    189 schema:familyName Falourd
    190 schema:givenName Xavier
    191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0774114624.38
    192 rdf:type schema:Person
    193 sg:pub.10.1007/s10570-010-9449-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1036083105
    194 https://doi.org/10.1007/s10570-010-9449-z
    195 rdf:type schema:CreativeWork
    196 sg:pub.10.1007/s10570-014-0434-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003369640
    197 https://doi.org/10.1007/s10570-014-0434-9
    198 rdf:type schema:CreativeWork
    199 sg:pub.10.1007/s10570-014-0459-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026694712
    200 https://doi.org/10.1007/s10570-014-0459-0
    201 rdf:type schema:CreativeWork
    202 sg:pub.10.1007/s10570-015-0586-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014618013
    203 https://doi.org/10.1007/s10570-015-0586-2
    204 rdf:type schema:CreativeWork
    205 sg:pub.10.1007/s10853-014-8609-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046746581
    206 https://doi.org/10.1007/s10853-014-8609-1
    207 rdf:type schema:CreativeWork
    208 sg:pub.10.1007/s12033-015-9887-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017273600
    209 https://doi.org/10.1007/s12033-015-9887-9
    210 rdf:type schema:CreativeWork
    211 sg:pub.10.1023/a:1009236932134 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038980198
    212 https://doi.org/10.1023/a:1009236932134
    213 rdf:type schema:CreativeWork
    214 sg:pub.10.1023/a:1016645809958 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004878902
    215 https://doi.org/10.1023/a:1016645809958
    216 rdf:type schema:CreativeWork
    217 sg:pub.10.1038/nchembio.2029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036828541
    218 https://doi.org/10.1038/nchembio.2029
    219 rdf:type schema:CreativeWork
    220 sg:pub.10.1038/ncomms11134 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053415325
    221 https://doi.org/10.1038/ncomms11134
    222 rdf:type schema:CreativeWork
    223 sg:pub.10.1038/srep18561 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003928386
    224 https://doi.org/10.1038/srep18561
    225 rdf:type schema:CreativeWork
    226 sg:pub.10.1038/srep28276 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052311837
    227 https://doi.org/10.1038/srep28276
    228 rdf:type schema:CreativeWork
    229 sg:pub.10.1186/1475-2859-9-58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016783089
    230 https://doi.org/10.1186/1475-2859-9-58
    231 rdf:type schema:CreativeWork
    232 sg:pub.10.1186/1754-6834-5-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015338590
    233 https://doi.org/10.1186/1754-6834-5-1
    234 rdf:type schema:CreativeWork
    235 sg:pub.10.1186/1754-6834-5-45 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002219986
    236 https://doi.org/10.1186/1754-6834-5-45
    237 rdf:type schema:CreativeWork
    238 sg:pub.10.1186/1754-6834-5-79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038416621
    239 https://doi.org/10.1186/1754-6834-5-79
    240 rdf:type schema:CreativeWork
    241 sg:pub.10.1186/1754-6834-6-41 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000812569
    242 https://doi.org/10.1186/1754-6834-6-41
    243 rdf:type schema:CreativeWork
    244 sg:pub.10.1186/s13068-014-0179-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035594727
    245 https://doi.org/10.1186/s13068-014-0179-6
    246 rdf:type schema:CreativeWork
    247 sg:pub.10.1186/s13068-015-0274-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046809495
    248 https://doi.org/10.1186/s13068-015-0274-3
    249 rdf:type schema:CreativeWork
    250 sg:pub.10.1186/s13068-015-0284-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015097541
    251 https://doi.org/10.1186/s13068-015-0284-1
    252 rdf:type schema:CreativeWork
    253 sg:pub.10.1186/s13068-015-0322-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1050098301
    254 https://doi.org/10.1186/s13068-015-0322-z
    255 rdf:type schema:CreativeWork
    256 sg:pub.10.1186/s13068-015-0407-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041990069
    257 https://doi.org/10.1186/s13068-015-0407-8
    258 rdf:type schema:CreativeWork
    259 sg:pub.10.1186/s13068-015-0423-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001820275
    260 https://doi.org/10.1186/s13068-015-0423-8
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1186/s13068-016-0441-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003905845
    263 https://doi.org/10.1186/s13068-016-0441-1
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1186/s13068-016-0520-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013257726
    266 https://doi.org/10.1186/s13068-016-0520-3
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1186/s13068-016-0594-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1010975174
    269 https://doi.org/10.1186/s13068-016-0594-y
    270 rdf:type schema:CreativeWork
    271 https://doi.org/10.1002/masy.19920610117 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051664567
    272 rdf:type schema:CreativeWork
    273 https://doi.org/10.1016/j.carbpol.2006.01.034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004501249
    274 rdf:type schema:CreativeWork
    275 https://doi.org/10.1016/j.cbpa.2014.02.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008420546
    276 rdf:type schema:CreativeWork
    277 https://doi.org/10.1016/j.chroma.2012.11.048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048414496
    278 rdf:type schema:CreativeWork
    279 https://doi.org/10.1016/j.eurpolymj.2007.05.038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035046756
    280 rdf:type schema:CreativeWork
    281 https://doi.org/10.1016/j.str.2012.04.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043963361
    282 rdf:type schema:CreativeWork
    283 https://doi.org/10.1016/j.tibtech.2015.09.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037667294
    284 rdf:type schema:CreativeWork
    285 https://doi.org/10.1016/s0008-6215(97)00130-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030840696
    286 rdf:type schema:CreativeWork
    287 https://doi.org/10.1016/s0008-6215(98)00236-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031185336
    288 rdf:type schema:CreativeWork
    289 https://doi.org/10.1016/s0144-8617(98)00021-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008737204
    290 rdf:type schema:CreativeWork
    291 https://doi.org/10.1016/s0926-2040(99)00043-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049590942
    292 rdf:type schema:CreativeWork
    293 https://doi.org/10.1021/bm0000337 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055219285
    294 rdf:type schema:CreativeWork
    295 https://doi.org/10.1021/bm0509725 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028891651
    296 rdf:type schema:CreativeWork
    297 https://doi.org/10.1021/bm061215p schema:sameAs https://app.dimensions.ai/details/publication/pub.1003859239
    298 rdf:type schema:CreativeWork
    299 https://doi.org/10.1021/cb200351y schema:sameAs https://app.dimensions.ai/details/publication/pub.1055226065
    300 rdf:type schema:CreativeWork
    301 https://doi.org/10.1021/ja210657t schema:sameAs https://app.dimensions.ai/details/publication/pub.1055851526
    302 rdf:type schema:CreativeWork
    303 https://doi.org/10.1021/ja409384b schema:sameAs https://app.dimensions.ai/details/publication/pub.1053121664
    304 rdf:type schema:CreativeWork
    305 https://doi.org/10.1042/bst20150204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056718004
    306 rdf:type schema:CreativeWork
    307 https://doi.org/10.1073/pnas.1323629111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000091224
    308 rdf:type schema:CreativeWork
    309 https://doi.org/10.1074/jbc.m113.459396 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000763727
    310 rdf:type schema:CreativeWork
    311 https://doi.org/10.1074/jbc.m113.530196 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005291541
    312 rdf:type schema:CreativeWork
    313 https://doi.org/10.1126/science.1137016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049275105
    314 rdf:type schema:CreativeWork
    315 https://doi.org/10.1126/science.aaf3165 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062667452
    316 rdf:type schema:CreativeWork
    317 https://doi.org/10.1128/aem.02942-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038177700
    318 rdf:type schema:CreativeWork
    319 https://doi.org/10.1146/annurev-biochem-060614-034439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020232116
    320 rdf:type schema:CreativeWork
    321 https://doi.org/10.1179/1743280415y.0000000009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018007197
    322 rdf:type schema:CreativeWork
    323 https://doi.org/10.1371/journal.pone.0027807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052692031
    324 rdf:type schema:CreativeWork
    325 https://doi.org/10.1371/journal.pone.0108313 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027061480
    326 rdf:type schema:CreativeWork
    327 https://doi.org/10.5936/csbj.201209019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011183943
    328 rdf:type schema:CreativeWork
    329 https://www.grid.ac/institutes/grid.460203.3 schema:alternateName Centre Angers-Nantes Pays de la Loire
    330 schema:name BIA, INRA, 44300, Nantes, France
    331 rdf:type schema:Organization
    332 https://www.grid.ac/institutes/grid.5399.6 schema:alternateName Aix-Marseille University
    333 schema:name Biodiversité et Biotechnologie Fongiques, INRA, Aix Marseille Univ, UMR1163, 13009, Marseille, France
    334 rdf:type schema:Organization
    335 https://www.grid.ac/institutes/grid.9026.d schema:alternateName University of Hamburg
    336 schema:name Chemical Wood Technology, University of Hamburg, Leuschnerstraße 91b, 21031 Hamburg, Germany
    337 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...