Fatal Community-acquired Pneumonia in Children Caused by Re-emergent Human Adenovirus 7d Associated with Higher Severity of Illness and Fatality Rate View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-12

AUTHORS

Zhiwu Yu, Zhiwei Zeng, Jing Zhang, Yuxian Pan, Manjun Chen, Yonghui Guo, Nan Yu, James Chodosh, Ning Fu, Xiaoyan Che, Qiwei Zhang

ABSTRACT

Human adenoviruses (HAdVs) are highly contagious pathogens causing acute respiratory disease (ARD), such as community-acquired pneumonia. HAdV-7d, a re-emergent genomic variant, has been recently reported in Asia and the United States after a several-decade absence. However, whether HAdV-7d is associated with higher severity than other types is currently unclear. In this study, the clinical and epidemiological investigation showed that fever, cough, and sore throat were the three most common respiratory symptoms of HAdV infections. HAdV-7 caused longer duration of fever, higher morbidity of tachypnea/dyspnea, pleural effusion, diarrhea, hepatosplenomegaly, consciousness alteration, as well as higher rates of pneumonia, mechanical ventilation and higher fatality rate (28.6%) than other types, particularly HAdV-3 and HAdV-2. The genomes of seven HAdV-7d isolates from mild, severe, and fatal cases were sequenced and highly similar with each other. Surprisingly, two isolates (2011, 2012) had 100% identical genomes with an earlier strain from a fatal ARD outbreak in China (2009), which elucidates the virus origin and confirms the unexpected HAdV genomic conservation and stability. Phylogenetic analysis indicated that L1 52/55-kDa DNA packaging protein may be associated with the higher severity of illness and fatality rate of HAdV-7. Clinicians need to be aware of HAdVs in children with ARD. More... »

PAGES

37216

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/srep37216

DOI

http://dx.doi.org/10.1038/srep37216

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1004946500

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27848998


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenovirus Infections, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenoviruses, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child, Preschool", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "China", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Communicable Diseases, Emerging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Community-Acquired Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Outbreaks", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant, Newborn", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phylogeny", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pneumonia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Respiratory Tract Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Southern Medical University", 
          "id": "https://www.grid.ac/institutes/grid.284723.8", 
          "name": [
            "Laboratory of Emerging Infectious Diseases and Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yu", 
        "givenName": "Zhiwu", 
        "id": "sg:person.015544564631.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015544564631.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Medical University", 
          "id": "https://www.grid.ac/institutes/grid.284723.8", 
          "name": [
            "Biosafety Level-3 Laboratory, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong 510515, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zeng", 
        "givenName": "Zhiwei", 
        "id": "sg:person.01150157672.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150157672.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Medical University", 
          "id": "https://www.grid.ac/institutes/grid.284723.8", 
          "name": [
            "Biosafety Level-3 Laboratory, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong 510515, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "Jing", 
        "id": "sg:person.01216273072.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01216273072.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Medical University", 
          "id": "https://www.grid.ac/institutes/grid.284723.8", 
          "name": [
            "Laboratory of Emerging Infectious Diseases and Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pan", 
        "givenName": "Yuxian", 
        "id": "sg:person.01013024051.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01013024051.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Medical University", 
          "id": "https://www.grid.ac/institutes/grid.284723.8", 
          "name": [
            "Laboratory of Emerging Infectious Diseases and Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "Manjun", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Medical University", 
          "id": "https://www.grid.ac/institutes/grid.284723.8", 
          "name": [
            "Laboratory of Emerging Infectious Diseases and Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guo", 
        "givenName": "Yonghui", 
        "id": "sg:person.0615304476.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615304476.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Medical University", 
          "id": "https://www.grid.ac/institutes/grid.284723.8", 
          "name": [
            "Laboratory of Emerging Infectious Diseases and Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yu", 
        "givenName": "Nan", 
        "id": "sg:person.0674514010.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674514010.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Harvard University", 
          "id": "https://www.grid.ac/institutes/grid.38142.3c", 
          "name": [
            "Department of Ophthalmology, Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chodosh", 
        "givenName": "James", 
        "id": "sg:person.01133520357.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133520357.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Medical University", 
          "id": "https://www.grid.ac/institutes/grid.284723.8", 
          "name": [
            "Laboratory of Emerging Infectious Diseases and Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fu", 
        "givenName": "Ning", 
        "id": "sg:person.01367035441.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367035441.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Medical University", 
          "id": "https://www.grid.ac/institutes/grid.284723.8", 
          "name": [
            "Laboratory of Emerging Infectious Diseases and Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Che", 
        "givenName": "Xiaoyan", 
        "id": "sg:person.01363434423.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363434423.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Harvard University", 
          "id": "https://www.grid.ac/institutes/grid.38142.3c", 
          "name": [
            "Biosafety Level-3 Laboratory, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong 510515, China.", 
            "Department of Ophthalmology, Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "Qiwei", 
        "id": "sg:person.01016073455.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016073455.49"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1128/jcm.01694-09", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000319790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.00848-07", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001212724"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid2206.151898", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002239208"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12250-013-3308-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002436132", 
          "https://doi.org/10.1007/s12250-013-3308-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-9071(199804)54:4<291::aid-jmv9>3.0.co;2-#", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002499617"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2164-13-341", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003392841", 
          "https://doi.org/10.1186/1471-2164-13-341"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/519938", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003565149"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.virol.2004.10.041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004064313"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-9071(199607)49:3<170::aid-jmv3>3.0.co;2-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006491984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-9071(199607)49:3<170::aid-jmv3>3.0.co;2-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006491984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/pubmed/fdu009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006816271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.79.4.2366-2374.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008100653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid2204.151595", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008263329"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmra011994", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008764541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmv.20745", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009946023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/23744235.2015.1055585", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010813197"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00705-014-2308-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012819775", 
          "https://doi.org/10.1007/s00705-014-2308-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/653083", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013151825"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.13-1186", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014434110"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.vaccine.2008.12.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014827205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/1708.101760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015003951"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0008145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015791903"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0053614", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015967994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.40.1.140-145.2002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017434812"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep07365", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020588144", 
          "https://doi.org/10.1038/srep07365"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.rmed.2013.09.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024451013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.00814-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026945880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jinf.2014.06.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029623122"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmv.10382", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030386639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep13617", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032410399", 
          "https://doi.org/10.1038/srep13617"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/320146", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033373663"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.02517-14", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034004783"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid2107.141443", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034851120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid1901.120423", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035691244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid0803.010190", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036230381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0123234", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037106105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0123234", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037106105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0155412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037422134"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0155412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037422134"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcv.2006.01.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039836282"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid1811.120629", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040633540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid2204.151403", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041282521"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/1348-0421.12074", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041763720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(05)71877-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043533523"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/irv.12118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046795911"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid1805.110865", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047339151"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.02225-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047492012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/cmr.00116-13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047744105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1405870", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049015513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1743-422x-8-23", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049270667", 
          "https://doi.org/10.1186/1743-422x-8-23"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/genomea.00182-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050093750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.41.10.4594-4599.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050333052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkg770", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050668915"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.01769-08", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052924145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s0950268899002149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054036531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s0950268899002149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054036531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/clinids/12.supplement_s870", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059471497"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/vir.0.81515-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060400962"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid1708.101760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071123199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3760/cma.j..issn.0253-9624.2011.09.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078490763"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079509440", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.aje.a113563", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1081668772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082918991", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083285344", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083315079", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-12", 
    "datePublishedReg": "2016-12-01", 
    "description": "Human adenoviruses (HAdVs) are highly contagious pathogens causing acute respiratory disease (ARD), such as community-acquired pneumonia. HAdV-7d, a re-emergent genomic variant, has been recently reported in Asia and the United States after a several-decade absence. However, whether HAdV-7d is associated with higher severity than other types is currently unclear. In this study, the clinical and epidemiological investigation showed that fever, cough, and sore throat were the three most common respiratory symptoms of HAdV infections. HAdV-7 caused longer duration of fever, higher morbidity of tachypnea/dyspnea, pleural effusion, diarrhea, hepatosplenomegaly, consciousness alteration, as well as higher rates of pneumonia, mechanical ventilation and higher fatality rate (28.6%) than other types, particularly HAdV-3 and HAdV-2. The genomes of seven HAdV-7d isolates from mild, severe, and fatal cases were sequenced and highly similar with each other. Surprisingly, two isolates (2011, 2012) had 100% identical genomes with an earlier strain from a fatal ARD outbreak in China (2009), which elucidates the virus origin and confirms the unexpected HAdV genomic conservation and stability. Phylogenetic analysis indicated that L1 52/55-kDa DNA packaging protein may be associated with the higher severity of illness and fatality rate of HAdV-7. Clinicians need to be aware of HAdVs in children with ARD.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/srep37216", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1045337", 
        "issn": [
          "2045-2322"
        ], 
        "name": "Scientific Reports", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "name": "Fatal Community-acquired Pneumonia in Children Caused by Re-emergent Human Adenovirus 7d Associated with Higher Severity of Illness and Fatality Rate", 
    "pagination": "37216", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "179254304417a052ed520e4b177d8aad8eb4ff732f8a8a71b1b8fde971c041a5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27848998"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101563288"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/srep37216"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1004946500"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/srep37216", 
      "https://app.dimensions.ai/details/publication/pub.1004946500"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T23:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8693_00000549.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/srep/2016/161116/srep37216/full/srep37216.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/srep37216'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/srep37216'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/srep37216'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/srep37216'


 

This table displays all metadata directly associated to this object as RDF triples.

399 TRIPLES      21 PREDICATES      108 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/srep37216 schema:about N0cfd1b868597438a85091ce146f16033
2 N0edb13ac693e46f4b9510a34f7919dcd
3 N2ccb05d9351c4ffe8bcb58f3adf5d805
4 N3ac60af817a548adbfaa93e535843c6c
5 N3c753c864761447faf4410ec0e244b4e
6 N6b8e48529bc448ef9316dee180474cc4
7 N6f0b7c70d6f54270938519b8b90e176c
8 N8d4ce838567643c5a0f3ce1b2a1ec37e
9 N935f962d894743ca991c63ba8789dd5c
10 N9afc032cad40465b9a8f27170843b2cb
11 N9d5726651c784b5888b6fd5f4dad7879
12 Na98efc5ed4d74e8f94bda732db3864a1
13 Nb3e20db1e61344868ce7e4942e5247b2
14 Nbee933ca3b004fd8a4dc7d97f023700a
15 Nf05cd100377a4d6494b7cbd211a01123
16 Nf2ebdff129a64c68a4f413c3b070c6e2
17 Nf93bfe8a74fa41079dd49ba839d30c1e
18 Nfebe2ceb38cc42f59c0743ac6becc7a4
19 anzsrc-for:11
20 anzsrc-for:1108
21 schema:author Nd2371c6a86624aeb9dee1760ed41c6bf
22 schema:citation sg:pub.10.1007/s00705-014-2308-8
23 sg:pub.10.1007/s12250-013-3308-7
24 sg:pub.10.1038/srep07365
25 sg:pub.10.1038/srep13617
26 sg:pub.10.1186/1471-2164-13-341
27 sg:pub.10.1186/1743-422x-8-23
28 https://app.dimensions.ai/details/publication/pub.1079509440
29 https://app.dimensions.ai/details/publication/pub.1082918991
30 https://app.dimensions.ai/details/publication/pub.1083285344
31 https://app.dimensions.ai/details/publication/pub.1083315079
32 https://doi.org/10.1002/(sici)1096-9071(199607)49:3<170::aid-jmv3>3.0.co;2-1
33 https://doi.org/10.1002/(sici)1096-9071(199804)54:4<291::aid-jmv9>3.0.co;2-#
34 https://doi.org/10.1002/jmv.10382
35 https://doi.org/10.1002/jmv.20745
36 https://doi.org/10.1016/j.jcv.2006.01.001
37 https://doi.org/10.1016/j.jinf.2014.06.015
38 https://doi.org/10.1016/j.rmed.2013.09.008
39 https://doi.org/10.1016/j.vaccine.2008.12.039
40 https://doi.org/10.1016/j.virol.2004.10.041
41 https://doi.org/10.1016/s0140-6736(05)71877-8
42 https://doi.org/10.1017/s0950268899002149
43 https://doi.org/10.1056/nejmoa1405870
44 https://doi.org/10.1056/nejmra011994
45 https://doi.org/10.1086/320146
46 https://doi.org/10.1086/519938
47 https://doi.org/10.1086/653083
48 https://doi.org/10.1093/clinids/12.supplement_s870
49 https://doi.org/10.1093/nar/gkg770
50 https://doi.org/10.1093/oxfordjournals.aje.a113563
51 https://doi.org/10.1093/pubmed/fdu009
52 https://doi.org/10.1099/vir.0.81515-0
53 https://doi.org/10.1111/1348-0421.12074
54 https://doi.org/10.1111/irv.12118
55 https://doi.org/10.1128/cmr.00116-13
56 https://doi.org/10.1128/genomea.00182-12
57 https://doi.org/10.1128/jcm.00848-07
58 https://doi.org/10.1128/jcm.01694-09
59 https://doi.org/10.1128/jcm.01769-08
60 https://doi.org/10.1128/jcm.02517-14
61 https://doi.org/10.1128/jcm.40.1.140-145.2002
62 https://doi.org/10.1128/jcm.41.10.4594-4599.2003
63 https://doi.org/10.1128/jvi.00814-12
64 https://doi.org/10.1128/jvi.02225-12
65 https://doi.org/10.1128/jvi.79.4.2366-2374.2005
66 https://doi.org/10.1371/journal.pone.0008145
67 https://doi.org/10.1371/journal.pone.0053614
68 https://doi.org/10.1371/journal.pone.0123234
69 https://doi.org/10.1371/journal.pone.0155412
70 https://doi.org/10.1378/chest.13-1186
71 https://doi.org/10.3109/23744235.2015.1055585
72 https://doi.org/10.3201/1708.101760
73 https://doi.org/10.3201/eid0803.010190
74 https://doi.org/10.3201/eid1708.101760
75 https://doi.org/10.3201/eid1805.110865
76 https://doi.org/10.3201/eid1811.120629
77 https://doi.org/10.3201/eid1901.120423
78 https://doi.org/10.3201/eid2107.141443
79 https://doi.org/10.3201/eid2204.151403
80 https://doi.org/10.3201/eid2204.151595
81 https://doi.org/10.3201/eid2206.151898
82 https://doi.org/10.3760/cma.j..issn.0253-9624.2011.09.013
83 schema:datePublished 2016-12
84 schema:datePublishedReg 2016-12-01
85 schema:description Human adenoviruses (HAdVs) are highly contagious pathogens causing acute respiratory disease (ARD), such as community-acquired pneumonia. HAdV-7d, a re-emergent genomic variant, has been recently reported in Asia and the United States after a several-decade absence. However, whether HAdV-7d is associated with higher severity than other types is currently unclear. In this study, the clinical and epidemiological investigation showed that fever, cough, and sore throat were the three most common respiratory symptoms of HAdV infections. HAdV-7 caused longer duration of fever, higher morbidity of tachypnea/dyspnea, pleural effusion, diarrhea, hepatosplenomegaly, consciousness alteration, as well as higher rates of pneumonia, mechanical ventilation and higher fatality rate (28.6%) than other types, particularly HAdV-3 and HAdV-2. The genomes of seven HAdV-7d isolates from mild, severe, and fatal cases were sequenced and highly similar with each other. Surprisingly, two isolates (2011, 2012) had 100% identical genomes with an earlier strain from a fatal ARD outbreak in China (2009), which elucidates the virus origin and confirms the unexpected HAdV genomic conservation and stability. Phylogenetic analysis indicated that L1 52/55-kDa DNA packaging protein may be associated with the higher severity of illness and fatality rate of HAdV-7. Clinicians need to be aware of HAdVs in children with ARD.
86 schema:genre research_article
87 schema:inLanguage en
88 schema:isAccessibleForFree true
89 schema:isPartOf N114a2f05e2b147e384a9a5bad9d4cfa4
90 Na281902da1db414f9773f0ace47d6a98
91 sg:journal.1045337
92 schema:name Fatal Community-acquired Pneumonia in Children Caused by Re-emergent Human Adenovirus 7d Associated with Higher Severity of Illness and Fatality Rate
93 schema:pagination 37216
94 schema:productId N6649b78b81f942fdac7bbc63fb5a4fdc
95 N7d69dba2b01b4736baf2ca840e639234
96 Na45c33e6f19c4de588fb2bb15be48e4e
97 Ne0a07d8d734c41539729d03fbe2ab7cf
98 Nf5258a3f47474f1ba55788a6210362e9
99 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004946500
100 https://doi.org/10.1038/srep37216
101 schema:sdDatePublished 2019-04-10T23:31
102 schema:sdLicense https://scigraph.springernature.com/explorer/license/
103 schema:sdPublisher Nc56b0c61ce31428d921b319971115602
104 schema:url http://www.nature.com/srep/2016/161116/srep37216/full/srep37216.html
105 sgo:license sg:explorer/license/
106 sgo:sdDataset articles
107 rdf:type schema:ScholarlyArticle
108 N0cfd1b868597438a85091ce146f16033 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Infant, Newborn
110 rdf:type schema:DefinedTerm
111 N0edb13ac693e46f4b9510a34f7919dcd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Adenovirus Infections, Human
113 rdf:type schema:DefinedTerm
114 N114a2f05e2b147e384a9a5bad9d4cfa4 schema:volumeNumber 6
115 rdf:type schema:PublicationVolume
116 N1d4a7cf4e62046c49cbed088577d91ae rdf:first sg:person.01216273072.08
117 rdf:rest N61df6bf3571649e0ae0461dc287c88d7
118 N2ccb05d9351c4ffe8bcb58f3adf5d805 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Adenoviruses, Human
120 rdf:type schema:DefinedTerm
121 N385e9f0acc8b47499df8a622e7b86dce rdf:first Nb04b6e7f229f4d03879dce1161bb5a24
122 rdf:rest N42c3e6bd933c4a73adf2e904619876f9
123 N3ac60af817a548adbfaa93e535843c6c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Respiratory Tract Infections
125 rdf:type schema:DefinedTerm
126 N3c753c864761447faf4410ec0e244b4e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Pneumonia
128 rdf:type schema:DefinedTerm
129 N42c3e6bd933c4a73adf2e904619876f9 rdf:first sg:person.0615304476.10
130 rdf:rest Nb8bf0e468a0944e69697681c8564b786
131 N5546243a905a4cfbba594a1947b4c00f rdf:first sg:person.01016073455.49
132 rdf:rest rdf:nil
133 N61df6bf3571649e0ae0461dc287c88d7 rdf:first sg:person.01013024051.28
134 rdf:rest N385e9f0acc8b47499df8a622e7b86dce
135 N6649b78b81f942fdac7bbc63fb5a4fdc schema:name dimensions_id
136 schema:value pub.1004946500
137 rdf:type schema:PropertyValue
138 N6b8e48529bc448ef9316dee180474cc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name China
140 rdf:type schema:DefinedTerm
141 N6f0b7c70d6f54270938519b8b90e176c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Phylogeny
143 rdf:type schema:DefinedTerm
144 N6f631b550c4e41259ea6e4c6ed073b6c rdf:first sg:person.01363434423.15
145 rdf:rest N5546243a905a4cfbba594a1947b4c00f
146 N729142703d6b4d3e88f04b9d2442d9eb rdf:first sg:person.01367035441.30
147 rdf:rest N6f631b550c4e41259ea6e4c6ed073b6c
148 N7d69dba2b01b4736baf2ca840e639234 schema:name doi
149 schema:value 10.1038/srep37216
150 rdf:type schema:PropertyValue
151 N8d4ce838567643c5a0f3ce1b2a1ec37e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Infant
153 rdf:type schema:DefinedTerm
154 N91ea2ec0e1ab40e4b08d8436d9d7f910 rdf:first sg:person.01133520357.47
155 rdf:rest N729142703d6b4d3e88f04b9d2442d9eb
156 N935f962d894743ca991c63ba8789dd5c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Child
158 rdf:type schema:DefinedTerm
159 N9afc032cad40465b9a8f27170843b2cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Humans
161 rdf:type schema:DefinedTerm
162 N9d5726651c784b5888b6fd5f4dad7879 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Male
164 rdf:type schema:DefinedTerm
165 Na281902da1db414f9773f0ace47d6a98 schema:issueNumber 1
166 rdf:type schema:PublicationIssue
167 Na45c33e6f19c4de588fb2bb15be48e4e schema:name nlm_unique_id
168 schema:value 101563288
169 rdf:type schema:PropertyValue
170 Na98efc5ed4d74e8f94bda732db3864a1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Child, Preschool
172 rdf:type schema:DefinedTerm
173 Nb04b6e7f229f4d03879dce1161bb5a24 schema:affiliation https://www.grid.ac/institutes/grid.284723.8
174 schema:familyName Chen
175 schema:givenName Manjun
176 rdf:type schema:Person
177 Nb3e20db1e61344868ce7e4942e5247b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Community-Acquired Infections
179 rdf:type schema:DefinedTerm
180 Nb8bf0e468a0944e69697681c8564b786 rdf:first sg:person.0674514010.21
181 rdf:rest N91ea2ec0e1ab40e4b08d8436d9d7f910
182 Nbee933ca3b004fd8a4dc7d97f023700a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Adolescent
184 rdf:type schema:DefinedTerm
185 Nc56b0c61ce31428d921b319971115602 schema:name Springer Nature - SN SciGraph project
186 rdf:type schema:Organization
187 Nccba5449ef4542438d621b6a375b8143 rdf:first sg:person.01150157672.69
188 rdf:rest N1d4a7cf4e62046c49cbed088577d91ae
189 Nd2371c6a86624aeb9dee1760ed41c6bf rdf:first sg:person.015544564631.51
190 rdf:rest Nccba5449ef4542438d621b6a375b8143
191 Ne0a07d8d734c41539729d03fbe2ab7cf schema:name pubmed_id
192 schema:value 27848998
193 rdf:type schema:PropertyValue
194 Nf05cd100377a4d6494b7cbd211a01123 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
195 schema:name Communicable Diseases, Emerging
196 rdf:type schema:DefinedTerm
197 Nf2ebdff129a64c68a4f413c3b070c6e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
198 schema:name Female
199 rdf:type schema:DefinedTerm
200 Nf5258a3f47474f1ba55788a6210362e9 schema:name readcube_id
201 schema:value 179254304417a052ed520e4b177d8aad8eb4ff732f8a8a71b1b8fde971c041a5
202 rdf:type schema:PropertyValue
203 Nf93bfe8a74fa41079dd49ba839d30c1e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
204 schema:name Disease Outbreaks
205 rdf:type schema:DefinedTerm
206 Nfebe2ceb38cc42f59c0743ac6becc7a4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
207 schema:name Survival Rate
208 rdf:type schema:DefinedTerm
209 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
210 schema:name Medical and Health Sciences
211 rdf:type schema:DefinedTerm
212 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
213 schema:name Medical Microbiology
214 rdf:type schema:DefinedTerm
215 sg:journal.1045337 schema:issn 2045-2322
216 schema:name Scientific Reports
217 rdf:type schema:Periodical
218 sg:person.01013024051.28 schema:affiliation https://www.grid.ac/institutes/grid.284723.8
219 schema:familyName Pan
220 schema:givenName Yuxian
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01013024051.28
222 rdf:type schema:Person
223 sg:person.01016073455.49 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
224 schema:familyName Zhang
225 schema:givenName Qiwei
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016073455.49
227 rdf:type schema:Person
228 sg:person.01133520357.47 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
229 schema:familyName Chodosh
230 schema:givenName James
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133520357.47
232 rdf:type schema:Person
233 sg:person.01150157672.69 schema:affiliation https://www.grid.ac/institutes/grid.284723.8
234 schema:familyName Zeng
235 schema:givenName Zhiwei
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150157672.69
237 rdf:type schema:Person
238 sg:person.01216273072.08 schema:affiliation https://www.grid.ac/institutes/grid.284723.8
239 schema:familyName Zhang
240 schema:givenName Jing
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01216273072.08
242 rdf:type schema:Person
243 sg:person.01363434423.15 schema:affiliation https://www.grid.ac/institutes/grid.284723.8
244 schema:familyName Che
245 schema:givenName Xiaoyan
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363434423.15
247 rdf:type schema:Person
248 sg:person.01367035441.30 schema:affiliation https://www.grid.ac/institutes/grid.284723.8
249 schema:familyName Fu
250 schema:givenName Ning
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367035441.30
252 rdf:type schema:Person
253 sg:person.015544564631.51 schema:affiliation https://www.grid.ac/institutes/grid.284723.8
254 schema:familyName Yu
255 schema:givenName Zhiwu
256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015544564631.51
257 rdf:type schema:Person
258 sg:person.0615304476.10 schema:affiliation https://www.grid.ac/institutes/grid.284723.8
259 schema:familyName Guo
260 schema:givenName Yonghui
261 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615304476.10
262 rdf:type schema:Person
263 sg:person.0674514010.21 schema:affiliation https://www.grid.ac/institutes/grid.284723.8
264 schema:familyName Yu
265 schema:givenName Nan
266 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674514010.21
267 rdf:type schema:Person
268 sg:pub.10.1007/s00705-014-2308-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012819775
269 https://doi.org/10.1007/s00705-014-2308-8
270 rdf:type schema:CreativeWork
271 sg:pub.10.1007/s12250-013-3308-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002436132
272 https://doi.org/10.1007/s12250-013-3308-7
273 rdf:type schema:CreativeWork
274 sg:pub.10.1038/srep07365 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020588144
275 https://doi.org/10.1038/srep07365
276 rdf:type schema:CreativeWork
277 sg:pub.10.1038/srep13617 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032410399
278 https://doi.org/10.1038/srep13617
279 rdf:type schema:CreativeWork
280 sg:pub.10.1186/1471-2164-13-341 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003392841
281 https://doi.org/10.1186/1471-2164-13-341
282 rdf:type schema:CreativeWork
283 sg:pub.10.1186/1743-422x-8-23 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049270667
284 https://doi.org/10.1186/1743-422x-8-23
285 rdf:type schema:CreativeWork
286 https://app.dimensions.ai/details/publication/pub.1079509440 schema:CreativeWork
287 https://app.dimensions.ai/details/publication/pub.1082918991 schema:CreativeWork
288 https://app.dimensions.ai/details/publication/pub.1083285344 schema:CreativeWork
289 https://app.dimensions.ai/details/publication/pub.1083315079 schema:CreativeWork
290 https://doi.org/10.1002/(sici)1096-9071(199607)49:3<170::aid-jmv3>3.0.co;2-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006491984
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1002/(sici)1096-9071(199804)54:4<291::aid-jmv9>3.0.co;2-# schema:sameAs https://app.dimensions.ai/details/publication/pub.1002499617
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1002/jmv.10382 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030386639
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1002/jmv.20745 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009946023
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1016/j.jcv.2006.01.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039836282
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1016/j.jinf.2014.06.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029623122
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1016/j.rmed.2013.09.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024451013
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1016/j.vaccine.2008.12.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014827205
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1016/j.virol.2004.10.041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004064313
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1016/s0140-6736(05)71877-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043533523
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1017/s0950268899002149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054036531
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1056/nejmoa1405870 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049015513
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1056/nejmra011994 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008764541
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1086/320146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033373663
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1086/519938 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003565149
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1086/653083 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013151825
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1093/clinids/12.supplement_s870 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059471497
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1093/nar/gkg770 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050668915
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1093/oxfordjournals.aje.a113563 schema:sameAs https://app.dimensions.ai/details/publication/pub.1081668772
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1093/pubmed/fdu009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006816271
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1099/vir.0.81515-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060400962
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1111/1348-0421.12074 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041763720
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1111/irv.12118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046795911
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1128/cmr.00116-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047744105
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1128/genomea.00182-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050093750
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1128/jcm.00848-07 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001212724
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1128/jcm.01694-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000319790
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1128/jcm.01769-08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052924145
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1128/jcm.02517-14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034004783
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1128/jcm.40.1.140-145.2002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017434812
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1128/jcm.41.10.4594-4599.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050333052
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1128/jvi.00814-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026945880
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1128/jvi.02225-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047492012
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1128/jvi.79.4.2366-2374.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008100653
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1371/journal.pone.0008145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015791903
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1371/journal.pone.0053614 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015967994
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1371/journal.pone.0123234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037106105
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1371/journal.pone.0155412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037422134
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1378/chest.13-1186 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014434110
367 rdf:type schema:CreativeWork
368 https://doi.org/10.3109/23744235.2015.1055585 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010813197
369 rdf:type schema:CreativeWork
370 https://doi.org/10.3201/1708.101760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015003951
371 rdf:type schema:CreativeWork
372 https://doi.org/10.3201/eid0803.010190 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036230381
373 rdf:type schema:CreativeWork
374 https://doi.org/10.3201/eid1708.101760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071123199
375 rdf:type schema:CreativeWork
376 https://doi.org/10.3201/eid1805.110865 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047339151
377 rdf:type schema:CreativeWork
378 https://doi.org/10.3201/eid1811.120629 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040633540
379 rdf:type schema:CreativeWork
380 https://doi.org/10.3201/eid1901.120423 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035691244
381 rdf:type schema:CreativeWork
382 https://doi.org/10.3201/eid2107.141443 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034851120
383 rdf:type schema:CreativeWork
384 https://doi.org/10.3201/eid2204.151403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041282521
385 rdf:type schema:CreativeWork
386 https://doi.org/10.3201/eid2204.151595 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008263329
387 rdf:type schema:CreativeWork
388 https://doi.org/10.3201/eid2206.151898 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002239208
389 rdf:type schema:CreativeWork
390 https://doi.org/10.3760/cma.j..issn.0253-9624.2011.09.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078490763
391 rdf:type schema:CreativeWork
392 https://www.grid.ac/institutes/grid.284723.8 schema:alternateName Southern Medical University
393 schema:name Biosafety Level-3 Laboratory, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong 510515, China.
394 Laboratory of Emerging Infectious Diseases and Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, China.
395 rdf:type schema:Organization
396 https://www.grid.ac/institutes/grid.38142.3c schema:alternateName Harvard University
397 schema:name Biosafety Level-3 Laboratory, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong 510515, China.
398 Department of Ophthalmology, Howe Laboratory, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.
399 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...