Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-12

AUTHORS

Mohammad Parvez, Lehlohonolo Benedict Qhanya, Ntsane Trevor Mthakathi, Ipeleng Kopano Rosinah Kgosiemang, Hans Denis Bamal, Nataraj Sekhar Pagadala, Ting Xie, Haoran Yang, Hengye Chen, Chrispian William Theron, Richie Monyaki, Seiso Caiphus Raselemane, Vuyani Salewe, Bogadi Lorato Mongale, Retshedisitswe Godfrey Matowane, Sara Mohamed Hasaan Abdalla, Wool Isaac Booi, Mari van Wyk, Dedré Olivier, Charlotte E Boucher, David R Nelson, Jack A Tuszynski, Jonathan Michael Blackburn, Jae-Hyuk Yu, Samson Sitheni Mashele, Wanping Chen, Khajamohiddin Syed

ABSTRACT

Since the initial identification of cytochrome P450 monooxygenases (CYPs/P450s), great progress has been made in understanding their structure-function relationship, diversity and application in producing compounds beneficial to humans. However, the molecular evolution of P450s in terms of their dynamics both at protein and DNA levels and functional conservation across kingdoms still needs investigation. In this study, we analyzed 17 598 P450s belonging to 113 P450 families (bacteria -42; fungi -19; plant -28; animal -22; plant and animal -1 and common P450 family -1) and found highly conserved and rapidly evolving P450 families. Results suggested that bacterial P450s, particularly P450s belonging to mycobacteria, are highly conserved both at protein and DNA levels. Mycobacteria possess the highest P450 diversity percentage compared to other microbes and have a high coverage of P450s (≥1%) in their genomes, as found in fungi and plants. Phylogenetic and functional analyses revealed the functional conservation of P450s despite belonging to different biological kingdoms, suggesting the adherence of P450s to their innate function such as their involvement in either generation or oxidation of steroids and structurally related molecules, fatty acids and terpenoids. This study's results offer new understanding of the dynamic structural nature of P450s. More... »

PAGES

33099

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/srep33099

DOI

http://dx.doi.org/10.1038/srep33099

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1002124311

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27616185


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cytochrome P-450 Enzyme System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Evolution, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Fungal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Plant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Dynamics Simulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mycobacterium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phylogeny", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Parvez", 
        "givenName": "Mohammad", 
        "id": "sg:person.01055364301.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055364301.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Qhanya", 
        "givenName": "Lehlohonolo Benedict", 
        "id": "sg:person.01306041301.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306041301.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mthakathi", 
        "givenName": "Ntsane Trevor", 
        "id": "sg:person.01354154501.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354154501.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kgosiemang", 
        "givenName": "Ipeleng Kopano Rosinah", 
        "id": "sg:person.01123477501.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123477501.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bamal", 
        "givenName": "Hans Denis", 
        "id": "sg:person.012455012545.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012455012545.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Alberta", 
          "id": "https://www.grid.ac/institutes/grid.17089.37", 
          "name": [
            "Department of Medical Microbiology and Immunology, 6-020 Katz Group Centre, University of Alberta, Edmonton, Alberta T6G 2E1, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pagadala", 
        "givenName": "Nataraj Sekhar", 
        "id": "sg:person.01307604560.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307604560.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Huazhong Agricultural University", 
          "id": "https://www.grid.ac/institutes/grid.35155.37", 
          "name": [
            "College of Informatics, Huazhong Agricultural University, Wuhan, Hubei Province, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Xie", 
        "givenName": "Ting", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Huazhong Agricultural University", 
          "id": "https://www.grid.ac/institutes/grid.35155.37", 
          "name": [
            "College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei Province, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yang", 
        "givenName": "Haoran", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Huazhong Agricultural University", 
          "id": "https://www.grid.ac/institutes/grid.35155.37", 
          "name": [
            "College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei Province, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "Hengye", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of the Free State", 
          "id": "https://www.grid.ac/institutes/grid.412219.d", 
          "name": [
            "Faculty of Natural and Agricultural Science, Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, P.O. Box 339, Bloemfontein, 9300, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Theron", 
        "givenName": "Chrispian William", 
        "id": "sg:person.0700615704.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700615704.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Monyaki", 
        "givenName": "Richie", 
        "id": "sg:person.01171612701.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171612701.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Raselemane", 
        "givenName": "Seiso Caiphus", 
        "id": "sg:person.01237726101.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237726101.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Salewe", 
        "givenName": "Vuyani", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mongale", 
        "givenName": "Bogadi Lorato", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matowane", 
        "givenName": "Retshedisitswe Godfrey", 
        "id": "sg:person.012523125745.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012523125745.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abdalla", 
        "givenName": "Sara Mohamed Hasaan", 
        "id": "sg:person.013320506345.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013320506345.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Booi", 
        "givenName": "Wool Isaac", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "van Wyk", 
        "givenName": "Mari", 
        "id": "sg:person.014713447345.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014713447345.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Olivier", 
        "givenName": "Dedr\u00e9", 
        "id": "sg:person.01207443642.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207443642.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of the Free State", 
          "id": "https://www.grid.ac/institutes/grid.412219.d", 
          "name": [
            "Faculty of Natural and Agricultural Science, Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, P.O. Box 339, Bloemfontein, 9300, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boucher", 
        "givenName": "Charlotte E", 
        "id": "sg:person.0632502504.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632502504.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tennessee Health Science Center", 
          "id": "https://www.grid.ac/institutes/grid.267301.1", 
          "name": [
            "Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nelson", 
        "givenName": "David R", 
        "id": "sg:person.0642103474.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642103474.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Alberta", 
          "id": "https://www.grid.ac/institutes/grid.17089.37", 
          "name": [
            "Department of Physics, University of Alberta, Edmonton, Alberta T6G 2J1, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tuszynski", 
        "givenName": "Jack A", 
        "id": "sg:person.01252076741.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252076741.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Cape Town", 
          "id": "https://www.grid.ac/institutes/grid.7836.a", 
          "name": [
            "Institute of Infectious Disease &Molecular Medicine; Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Blackburn", 
        "givenName": "Jonathan Michael", 
        "id": "sg:person.01034607676.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034607676.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Wisconsin\u2013Madison", 
          "id": "https://www.grid.ac/institutes/grid.14003.36", 
          "name": [
            "Department of Bacteriology, University of Wisconsin-Madison, 3155 MSB, 1550 Linden Drive, Madison WI 53706, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yu", 
        "givenName": "Jae-Hyuk", 
        "id": "sg:person.0621715152.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621715152.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mashele", 
        "givenName": "Samson Sitheni", 
        "id": "sg:person.01310346360.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310346360.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Huazhong Agricultural University", 
          "id": "https://www.grid.ac/institutes/grid.35155.37", 
          "name": [
            "College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei Province, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "Wanping", 
        "id": "sg:person.0742525010.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742525010.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central University of Technology", 
          "id": "https://www.grid.ac/institutes/grid.428369.2", 
          "name": [
            "Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Syed", 
        "givenName": "Khajamohiddin", 
        "id": "sg:person.0716036136.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716036136.69"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1371/journal.pcbi.1002195", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001034143"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-319-12108-6_8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001557253", 
          "https://doi.org/10.1007/978-3-319-12108-6_8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2011.02.121", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003412510"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0142100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005723925"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m109.072132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006176505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m110.161117", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007008696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev-arplant-042809-112305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009024759"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.00286-06", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009163899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.meegid.2011.05.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009460938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsb0297-140", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009782445", 
          "https://doi.org/10.1038/nsb0297-140"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkt1223", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010707975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0086683", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011461425"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0907398106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011628709"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/molbev/msw054", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012564990"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/abbi.1999.1352", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012626093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.110.155119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013244354"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0095616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014270316"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rstb.2012.0476", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014680783"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3852/13-002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017279706"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-319-12108-6_7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017788699", 
          "https://doi.org/10.1007/978-3-319-12108-6_7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btl529", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019858005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep11572", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020505934", 
          "https://doi.org/10.1038/srep11572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep11572", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020505934", 
          "https://doi.org/10.1038/srep11572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gbe/evu132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020610574"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rstb.2012.0428", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020638296"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2958.2003.03425.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020808451"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-319-12108-6_1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021403019", 
          "https://doi.org/10.1007/978-3-319-12108-6_1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rstb.2012.0430", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021983247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00203-011-0753-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022848793", 
          "https://doi.org/10.1007/s00203-011-0753-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2091-10-27", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023356440", 
          "https://doi.org/10.1186/1471-2091-10-27"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbapap.2010.08.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025769303"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0100059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027740752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/molbev/msp077", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028540883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/molbev/msp077", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028540883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0742-8413(98)10027-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029746602"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2164-13-525", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031009486", 
          "https://doi.org/10.1186/1471-2164-13-525"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13258-013-0170-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031553107", 
          "https://doi.org/10.1007/s13258-013-0170-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.2000.3030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032475280"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1479-7364-4-1-59", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036064711", 
          "https://doi.org/10.1186/1479-7364-4-1-59"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0107209", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036753549"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkn072", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038133966"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m109.032706", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038959519"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mmbr.00005-07", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039013531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-319-12108-6_9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039789769", 
          "https://doi.org/10.1007/978-3-319-12108-6_9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2105-5-113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040413794", 
          "https://doi.org/10.1186/1471-2105-5-113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.abb.2009.07.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041722547"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbapap.2010.06.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042790849"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m110.164293", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043438169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-319-12108-6_6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043577482", 
          "https://doi.org/10.1007/978-3-319-12108-6_6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/16.7.660", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047230091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkt1183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047265540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m114.602771", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047854812"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbagen.2006.07.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049074690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbagen.2006.07.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049074690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m802115200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053277690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rstb.2012.0426", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053293689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a021870", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059960672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a021870", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059960672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1556/amicr.58.2011.3.4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067879378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077121078", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077121078", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.molbev.a040471", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079778351"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.molbev.a040023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082762864"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.8.12.1233", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083369515"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-12", 
    "datePublishedReg": "2016-12-01", 
    "description": "Since the initial identification of cytochrome P450 monooxygenases (CYPs/P450s), great progress has been made in understanding their structure-function relationship, diversity and application in producing compounds beneficial to humans. However, the molecular evolution of P450s in terms of their dynamics both at protein and DNA levels and functional conservation across kingdoms still needs investigation. In this study, we analyzed 17 598 P450s belonging to 113 P450 families (bacteria -42; fungi -19; plant -28; animal -22; plant and animal -1 and common P450 family -1) and found highly conserved and rapidly evolving P450 families. Results suggested that bacterial P450s, particularly P450s belonging to mycobacteria, are highly conserved both at protein and DNA levels. Mycobacteria possess the highest P450 diversity percentage compared to other microbes and have a high coverage of P450s (\u22651%) in their genomes, as found in fungi and plants. Phylogenetic and functional analyses revealed the functional conservation of P450s despite belonging to different biological kingdoms, suggesting the adherence of P450s to their innate function such as their involvement in either generation or oxidation of steroids and structurally related molecules, fatty acids and terpenoids. This study's results offer new understanding of the dynamic structural nature of P450s.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/srep33099", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1045337", 
        "issn": [
          "2045-2322"
        ], 
        "name": "Scientific Reports", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "name": "Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s", 
    "pagination": "33099", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "0a1dd625c911e0a62f6ead4460fc4975be93b9a001dc8f9d6f9d89419063b0ed"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27616185"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101563288"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/srep33099"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1002124311"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/srep33099", 
      "https://app.dimensions.ai/details/publication/pub.1002124311"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T15:58", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8664_00000549.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/srep/2016/160912/srep33099/full/srep33099.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/srep33099'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/srep33099'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/srep33099'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/srep33099'


 

This table displays all metadata directly associated to this object as RDF triples.

489 TRIPLES      21 PREDICATES      97 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/srep33099 schema:about N0d331d87c3a44529bd5c2b98b5b7ae28
2 N42c4bc8d2b4145fa8a4d91023ad94f29
3 N4fc11cd7fc1f48cf93c65e6639b65de3
4 N579bd01f596a401fb5066071778d12e8
5 N7e7c5bd443a943f5b26b810442482d11
6 N8972d493dc514aaba6938a22c6449c69
7 N9e008a6667e1432392eed12b5ef91484
8 Nc21705cac99745b4bbd1fa9ea848dd8d
9 Nd9f1bc3b0aa543d8bf4ff4548f08045e
10 anzsrc-for:06
11 anzsrc-for:0601
12 schema:author N937697feb195421db1bcca86d6d12dcd
13 schema:citation sg:pub.10.1007/978-3-319-12108-6_1
14 sg:pub.10.1007/978-3-319-12108-6_6
15 sg:pub.10.1007/978-3-319-12108-6_7
16 sg:pub.10.1007/978-3-319-12108-6_8
17 sg:pub.10.1007/978-3-319-12108-6_9
18 sg:pub.10.1007/s00203-011-0753-2
19 sg:pub.10.1007/s13258-013-0170-9
20 sg:pub.10.1038/nsb0297-140
21 sg:pub.10.1038/srep11572
22 sg:pub.10.1186/1471-2091-10-27
23 sg:pub.10.1186/1471-2105-5-113
24 sg:pub.10.1186/1471-2164-13-525
25 sg:pub.10.1186/1479-7364-4-1-59
26 https://app.dimensions.ai/details/publication/pub.1077121078
27 https://doi.org/10.1006/abbi.1999.1352
28 https://doi.org/10.1006/bbrc.2000.3030
29 https://doi.org/10.1016/j.abb.2009.07.011
30 https://doi.org/10.1016/j.bbagen.2006.07.018
31 https://doi.org/10.1016/j.bbapap.2010.06.012
32 https://doi.org/10.1016/j.bbapap.2010.08.008
33 https://doi.org/10.1016/j.bbrc.2011.02.121
34 https://doi.org/10.1016/j.meegid.2011.05.025
35 https://doi.org/10.1016/s0742-8413(98)10027-0
36 https://doi.org/10.1046/j.1365-2958.2003.03425.x
37 https://doi.org/10.1073/pnas.0907398106
38 https://doi.org/10.1074/jbc.m109.032706
39 https://doi.org/10.1074/jbc.m109.072132
40 https://doi.org/10.1074/jbc.m110.161117
41 https://doi.org/10.1074/jbc.m110.164293
42 https://doi.org/10.1074/jbc.m114.602771
43 https://doi.org/10.1074/jbc.m802115200
44 https://doi.org/10.1093/bioinformatics/16.7.660
45 https://doi.org/10.1093/bioinformatics/btl529
46 https://doi.org/10.1093/gbe/evu132
47 https://doi.org/10.1093/molbev/msp077
48 https://doi.org/10.1093/molbev/msw054
49 https://doi.org/10.1093/nar/gkn072
50 https://doi.org/10.1093/nar/gkt1183
51 https://doi.org/10.1093/nar/gkt1223
52 https://doi.org/10.1093/oxfordjournals.jbchem.a021870
53 https://doi.org/10.1093/oxfordjournals.molbev.a040023
54 https://doi.org/10.1093/oxfordjournals.molbev.a040471
55 https://doi.org/10.1098/rstb.2012.0426
56 https://doi.org/10.1098/rstb.2012.0428
57 https://doi.org/10.1098/rstb.2012.0430
58 https://doi.org/10.1098/rstb.2012.0476
59 https://doi.org/10.1101/gr.8.12.1233
60 https://doi.org/10.1104/pp.110.155119
61 https://doi.org/10.1128/jb.00286-06
62 https://doi.org/10.1128/mmbr.00005-07
63 https://doi.org/10.1146/annurev-arplant-042809-112305
64 https://doi.org/10.1371/journal.pcbi.1002195
65 https://doi.org/10.1371/journal.pone.0086683
66 https://doi.org/10.1371/journal.pone.0095616
67 https://doi.org/10.1371/journal.pone.0100059
68 https://doi.org/10.1371/journal.pone.0107209
69 https://doi.org/10.1371/journal.pone.0142100
70 https://doi.org/10.1556/amicr.58.2011.3.4
71 https://doi.org/10.3852/13-002
72 schema:datePublished 2016-12
73 schema:datePublishedReg 2016-12-01
74 schema:description Since the initial identification of cytochrome P450 monooxygenases (CYPs/P450s), great progress has been made in understanding their structure-function relationship, diversity and application in producing compounds beneficial to humans. However, the molecular evolution of P450s in terms of their dynamics both at protein and DNA levels and functional conservation across kingdoms still needs investigation. In this study, we analyzed 17 598 P450s belonging to 113 P450 families (bacteria -42; fungi -19; plant -28; animal -22; plant and animal -1 and common P450 family -1) and found highly conserved and rapidly evolving P450 families. Results suggested that bacterial P450s, particularly P450s belonging to mycobacteria, are highly conserved both at protein and DNA levels. Mycobacteria possess the highest P450 diversity percentage compared to other microbes and have a high coverage of P450s (≥1%) in their genomes, as found in fungi and plants. Phylogenetic and functional analyses revealed the functional conservation of P450s despite belonging to different biological kingdoms, suggesting the adherence of P450s to their innate function such as their involvement in either generation or oxidation of steroids and structurally related molecules, fatty acids and terpenoids. This study's results offer new understanding of the dynamic structural nature of P450s.
75 schema:genre research_article
76 schema:inLanguage en
77 schema:isAccessibleForFree true
78 schema:isPartOf N80a7246f0db842dfa09cf39a698ca335
79 Ndda4d2272fce4b1682d6e8fa2bbd5d72
80 sg:journal.1045337
81 schema:name Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s
82 schema:pagination 33099
83 schema:productId N26c4dfb2f87d419d88128970c3a7e5eb
84 N7962f7f641554d5f9637d2384f0ff084
85 Nb6f132ff92fe4d97806fd05cb3963de3
86 Nbf0a153eabba4908b5600ea828782098
87 Nd21ad6cdd34d4534bae00b6888e0794c
88 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002124311
89 https://doi.org/10.1038/srep33099
90 schema:sdDatePublished 2019-04-10T15:58
91 schema:sdLicense https://scigraph.springernature.com/explorer/license/
92 schema:sdPublisher N77d4fbb0d6c84f37873c24568b0a185b
93 schema:url http://www.nature.com/srep/2016/160912/srep33099/full/srep33099.html
94 sgo:license sg:explorer/license/
95 sgo:sdDataset articles
96 rdf:type schema:ScholarlyArticle
97 N08568228489a4d12b3c764bc3a7f2065 rdf:first sg:person.014713447345.84
98 rdf:rest N5f6e43d924f84491b3cf99bdd6515406
99 N0d331d87c3a44529bd5c2b98b5b7ae28 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Molecular Dynamics Simulation
101 rdf:type schema:DefinedTerm
102 N1def932c8ff14725ac49a890cb77bfb0 rdf:first sg:person.01237726101.82
103 rdf:rest Ne0e388900c2a464c9737794aec01f6d9
104 N24f74e6d1527414492330e6da785a17e rdf:first sg:person.0700615704.90
105 rdf:rest Nf3ef48cf4ef647f687401da953e78d7c
106 N26c4dfb2f87d419d88128970c3a7e5eb schema:name readcube_id
107 schema:value 0a1dd625c911e0a62f6ead4460fc4975be93b9a001dc8f9d6f9d89419063b0ed
108 rdf:type schema:PropertyValue
109 N3147dea16d354a6b8be308cf017babc3 schema:affiliation https://www.grid.ac/institutes/grid.35155.37
110 schema:familyName Yang
111 schema:givenName Haoran
112 rdf:type schema:Person
113 N3d3a2be06a7b4f99a128a2cc72a3ed28 rdf:first sg:person.01354154501.17
114 rdf:rest N8152d30ff7a249e395e617e54f00bd01
115 N40244ec8c9124bc4a484544c0477c4b3 rdf:first sg:person.012523125745.27
116 rdf:rest N6c66a7fe397e42718ee7190397dcfff6
117 N42c4bc8d2b4145fa8a4d91023ad94f29 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Genome, Bacterial
119 rdf:type schema:DefinedTerm
120 N45d4700089214521a95f6a2f73e6aacc rdf:first sg:person.01306041301.29
121 rdf:rest N3d3a2be06a7b4f99a128a2cc72a3ed28
122 N4fc11cd7fc1f48cf93c65e6639b65de3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Evolution, Molecular
124 rdf:type schema:DefinedTerm
125 N54544bb0f6e04941b7165fdb0d7839af rdf:first sg:person.01034607676.12
126 rdf:rest Ndd053312eb8f4e5682966a920d22346b
127 N579bd01f596a401fb5066071778d12e8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Phylogeny
129 rdf:type schema:DefinedTerm
130 N5f6e43d924f84491b3cf99bdd6515406 rdf:first sg:person.01207443642.66
131 rdf:rest Nb70ab3d6981a4ce6846c05e591f3db59
132 N65b6fc982d404937a2fb68c07951a2d1 schema:affiliation https://www.grid.ac/institutes/grid.35155.37
133 schema:familyName Xie
134 schema:givenName Ting
135 rdf:type schema:Person
136 N67c3fb166b054f76b360f7aa1fde95cd rdf:first sg:person.012455012545.30
137 rdf:rest Nea8ee0ead6974fd383473ffc80a7d2c6
138 N6c66a7fe397e42718ee7190397dcfff6 rdf:first sg:person.013320506345.52
139 rdf:rest N88b1e8045c64460780e32e6b7e0e6761
140 N75d080daf439442d94831427cc6d969a schema:affiliation https://www.grid.ac/institutes/grid.428369.2
141 schema:familyName Mongale
142 schema:givenName Bogadi Lorato
143 rdf:type schema:Person
144 N77d4fbb0d6c84f37873c24568b0a185b schema:name Springer Nature - SN SciGraph project
145 rdf:type schema:Organization
146 N7962f7f641554d5f9637d2384f0ff084 schema:name pubmed_id
147 schema:value 27616185
148 rdf:type schema:PropertyValue
149 N7e0666a4a0c34b01a3a3f9fe819cd032 rdf:first sg:person.0642103474.70
150 rdf:rest Naeeff21039a14e0fa034515e37e1d588
151 N7e7c5bd443a943f5b26b810442482d11 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Genome, Fungal
153 rdf:type schema:DefinedTerm
154 N80a7246f0db842dfa09cf39a698ca335 schema:issueNumber 1
155 rdf:type schema:PublicationIssue
156 N8152d30ff7a249e395e617e54f00bd01 rdf:first sg:person.01123477501.14
157 rdf:rest N67c3fb166b054f76b360f7aa1fde95cd
158 N88b1e8045c64460780e32e6b7e0e6761 rdf:first N9deda693da2f4436b837ac0128d7b720
159 rdf:rest N08568228489a4d12b3c764bc3a7f2065
160 N8972d493dc514aaba6938a22c6449c69 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Cytochrome P-450 Enzyme System
162 rdf:type schema:DefinedTerm
163 N937697feb195421db1bcca86d6d12dcd rdf:first sg:person.01055364301.08
164 rdf:rest N45d4700089214521a95f6a2f73e6aacc
165 N9deda693da2f4436b837ac0128d7b720 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
166 schema:familyName Booi
167 schema:givenName Wool Isaac
168 rdf:type schema:Person
169 N9e008a6667e1432392eed12b5ef91484 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Animals
171 rdf:type schema:DefinedTerm
172 Nac836b9838084a0fbaac6af216ae5809 rdf:first sg:person.0716036136.69
173 rdf:rest rdf:nil
174 Nae40581e0d2f49dda6f7d564a5d1dfe0 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
175 schema:familyName Salewe
176 schema:givenName Vuyani
177 rdf:type schema:Person
178 Naeeff21039a14e0fa034515e37e1d588 rdf:first sg:person.01252076741.81
179 rdf:rest N54544bb0f6e04941b7165fdb0d7839af
180 Nb6f132ff92fe4d97806fd05cb3963de3 schema:name dimensions_id
181 schema:value pub.1002124311
182 rdf:type schema:PropertyValue
183 Nb70ab3d6981a4ce6846c05e591f3db59 rdf:first sg:person.0632502504.39
184 rdf:rest N7e0666a4a0c34b01a3a3f9fe819cd032
185 Nbf0a153eabba4908b5600ea828782098 schema:name nlm_unique_id
186 schema:value 101563288
187 rdf:type schema:PropertyValue
188 Nc21705cac99745b4bbd1fa9ea848dd8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Mycobacterium
190 rdf:type schema:DefinedTerm
191 Ncbb23fea2f2b40ada478ee2fbf9dd20c rdf:first N3147dea16d354a6b8be308cf017babc3
192 rdf:rest Ne6bba834effc4f73b552b0c55b821f61
193 Nd21ad6cdd34d4534bae00b6888e0794c schema:name doi
194 schema:value 10.1038/srep33099
195 rdf:type schema:PropertyValue
196 Nd9f1bc3b0aa543d8bf4ff4548f08045e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Genome, Plant
198 rdf:type schema:DefinedTerm
199 Ndd053312eb8f4e5682966a920d22346b rdf:first sg:person.0621715152.69
200 rdf:rest Ne6917b5382c4427aab86a020956bbd47
201 Ndda4d2272fce4b1682d6e8fa2bbd5d72 schema:volumeNumber 6
202 rdf:type schema:PublicationVolume
203 Ndedcfddbef6d45058a57b71b8eef02b8 rdf:first sg:person.0742525010.90
204 rdf:rest Nac836b9838084a0fbaac6af216ae5809
205 Ne0e388900c2a464c9737794aec01f6d9 rdf:first Nae40581e0d2f49dda6f7d564a5d1dfe0
206 rdf:rest Nfebccc2c0efd445f91db7c4b0ffe34bf
207 Ne6917b5382c4427aab86a020956bbd47 rdf:first sg:person.01310346360.60
208 rdf:rest Ndedcfddbef6d45058a57b71b8eef02b8
209 Ne6bba834effc4f73b552b0c55b821f61 rdf:first Nee0979e840c042ed8bd0f689f13d8a8d
210 rdf:rest N24f74e6d1527414492330e6da785a17e
211 Nea8ee0ead6974fd383473ffc80a7d2c6 rdf:first sg:person.01307604560.18
212 rdf:rest Nfbc9ce7bffbd458384d9506a649a0d41
213 Nee0979e840c042ed8bd0f689f13d8a8d schema:affiliation https://www.grid.ac/institutes/grid.35155.37
214 schema:familyName Chen
215 schema:givenName Hengye
216 rdf:type schema:Person
217 Nf3ef48cf4ef647f687401da953e78d7c rdf:first sg:person.01171612701.41
218 rdf:rest N1def932c8ff14725ac49a890cb77bfb0
219 Nfbc9ce7bffbd458384d9506a649a0d41 rdf:first N65b6fc982d404937a2fb68c07951a2d1
220 rdf:rest Ncbb23fea2f2b40ada478ee2fbf9dd20c
221 Nfebccc2c0efd445f91db7c4b0ffe34bf rdf:first N75d080daf439442d94831427cc6d969a
222 rdf:rest N40244ec8c9124bc4a484544c0477c4b3
223 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
224 schema:name Biological Sciences
225 rdf:type schema:DefinedTerm
226 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
227 schema:name Biochemistry and Cell Biology
228 rdf:type schema:DefinedTerm
229 sg:journal.1045337 schema:issn 2045-2322
230 schema:name Scientific Reports
231 rdf:type schema:Periodical
232 sg:person.01034607676.12 schema:affiliation https://www.grid.ac/institutes/grid.7836.a
233 schema:familyName Blackburn
234 schema:givenName Jonathan Michael
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034607676.12
236 rdf:type schema:Person
237 sg:person.01055364301.08 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
238 schema:familyName Parvez
239 schema:givenName Mohammad
240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055364301.08
241 rdf:type schema:Person
242 sg:person.01123477501.14 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
243 schema:familyName Kgosiemang
244 schema:givenName Ipeleng Kopano Rosinah
245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123477501.14
246 rdf:type schema:Person
247 sg:person.01171612701.41 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
248 schema:familyName Monyaki
249 schema:givenName Richie
250 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171612701.41
251 rdf:type schema:Person
252 sg:person.01207443642.66 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
253 schema:familyName Olivier
254 schema:givenName Dedré
255 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207443642.66
256 rdf:type schema:Person
257 sg:person.01237726101.82 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
258 schema:familyName Raselemane
259 schema:givenName Seiso Caiphus
260 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237726101.82
261 rdf:type schema:Person
262 sg:person.012455012545.30 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
263 schema:familyName Bamal
264 schema:givenName Hans Denis
265 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012455012545.30
266 rdf:type schema:Person
267 sg:person.01252076741.81 schema:affiliation https://www.grid.ac/institutes/grid.17089.37
268 schema:familyName Tuszynski
269 schema:givenName Jack A
270 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252076741.81
271 rdf:type schema:Person
272 sg:person.012523125745.27 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
273 schema:familyName Matowane
274 schema:givenName Retshedisitswe Godfrey
275 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012523125745.27
276 rdf:type schema:Person
277 sg:person.01306041301.29 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
278 schema:familyName Qhanya
279 schema:givenName Lehlohonolo Benedict
280 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306041301.29
281 rdf:type schema:Person
282 sg:person.01307604560.18 schema:affiliation https://www.grid.ac/institutes/grid.17089.37
283 schema:familyName Pagadala
284 schema:givenName Nataraj Sekhar
285 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307604560.18
286 rdf:type schema:Person
287 sg:person.01310346360.60 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
288 schema:familyName Mashele
289 schema:givenName Samson Sitheni
290 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310346360.60
291 rdf:type schema:Person
292 sg:person.013320506345.52 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
293 schema:familyName Abdalla
294 schema:givenName Sara Mohamed Hasaan
295 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013320506345.52
296 rdf:type schema:Person
297 sg:person.01354154501.17 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
298 schema:familyName Mthakathi
299 schema:givenName Ntsane Trevor
300 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354154501.17
301 rdf:type schema:Person
302 sg:person.014713447345.84 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
303 schema:familyName van Wyk
304 schema:givenName Mari
305 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014713447345.84
306 rdf:type schema:Person
307 sg:person.0621715152.69 schema:affiliation https://www.grid.ac/institutes/grid.14003.36
308 schema:familyName Yu
309 schema:givenName Jae-Hyuk
310 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621715152.69
311 rdf:type schema:Person
312 sg:person.0632502504.39 schema:affiliation https://www.grid.ac/institutes/grid.412219.d
313 schema:familyName Boucher
314 schema:givenName Charlotte E
315 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632502504.39
316 rdf:type schema:Person
317 sg:person.0642103474.70 schema:affiliation https://www.grid.ac/institutes/grid.267301.1
318 schema:familyName Nelson
319 schema:givenName David R
320 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642103474.70
321 rdf:type schema:Person
322 sg:person.0700615704.90 schema:affiliation https://www.grid.ac/institutes/grid.412219.d
323 schema:familyName Theron
324 schema:givenName Chrispian William
325 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700615704.90
326 rdf:type schema:Person
327 sg:person.0716036136.69 schema:affiliation https://www.grid.ac/institutes/grid.428369.2
328 schema:familyName Syed
329 schema:givenName Khajamohiddin
330 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716036136.69
331 rdf:type schema:Person
332 sg:person.0742525010.90 schema:affiliation https://www.grid.ac/institutes/grid.35155.37
333 schema:familyName Chen
334 schema:givenName Wanping
335 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742525010.90
336 rdf:type schema:Person
337 sg:pub.10.1007/978-3-319-12108-6_1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021403019
338 https://doi.org/10.1007/978-3-319-12108-6_1
339 rdf:type schema:CreativeWork
340 sg:pub.10.1007/978-3-319-12108-6_6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043577482
341 https://doi.org/10.1007/978-3-319-12108-6_6
342 rdf:type schema:CreativeWork
343 sg:pub.10.1007/978-3-319-12108-6_7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017788699
344 https://doi.org/10.1007/978-3-319-12108-6_7
345 rdf:type schema:CreativeWork
346 sg:pub.10.1007/978-3-319-12108-6_8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001557253
347 https://doi.org/10.1007/978-3-319-12108-6_8
348 rdf:type schema:CreativeWork
349 sg:pub.10.1007/978-3-319-12108-6_9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039789769
350 https://doi.org/10.1007/978-3-319-12108-6_9
351 rdf:type schema:CreativeWork
352 sg:pub.10.1007/s00203-011-0753-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022848793
353 https://doi.org/10.1007/s00203-011-0753-2
354 rdf:type schema:CreativeWork
355 sg:pub.10.1007/s13258-013-0170-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031553107
356 https://doi.org/10.1007/s13258-013-0170-9
357 rdf:type schema:CreativeWork
358 sg:pub.10.1038/nsb0297-140 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009782445
359 https://doi.org/10.1038/nsb0297-140
360 rdf:type schema:CreativeWork
361 sg:pub.10.1038/srep11572 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020505934
362 https://doi.org/10.1038/srep11572
363 rdf:type schema:CreativeWork
364 sg:pub.10.1186/1471-2091-10-27 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023356440
365 https://doi.org/10.1186/1471-2091-10-27
366 rdf:type schema:CreativeWork
367 sg:pub.10.1186/1471-2105-5-113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040413794
368 https://doi.org/10.1186/1471-2105-5-113
369 rdf:type schema:CreativeWork
370 sg:pub.10.1186/1471-2164-13-525 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031009486
371 https://doi.org/10.1186/1471-2164-13-525
372 rdf:type schema:CreativeWork
373 sg:pub.10.1186/1479-7364-4-1-59 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036064711
374 https://doi.org/10.1186/1479-7364-4-1-59
375 rdf:type schema:CreativeWork
376 https://app.dimensions.ai/details/publication/pub.1077121078 schema:CreativeWork
377 https://doi.org/10.1006/abbi.1999.1352 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012626093
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1006/bbrc.2000.3030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032475280
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1016/j.abb.2009.07.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041722547
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1016/j.bbagen.2006.07.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049074690
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1016/j.bbapap.2010.06.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042790849
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1016/j.bbapap.2010.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025769303
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1016/j.bbrc.2011.02.121 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003412510
390 rdf:type schema:CreativeWork
391 https://doi.org/10.1016/j.meegid.2011.05.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009460938
392 rdf:type schema:CreativeWork
393 https://doi.org/10.1016/s0742-8413(98)10027-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029746602
394 rdf:type schema:CreativeWork
395 https://doi.org/10.1046/j.1365-2958.2003.03425.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020808451
396 rdf:type schema:CreativeWork
397 https://doi.org/10.1073/pnas.0907398106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011628709
398 rdf:type schema:CreativeWork
399 https://doi.org/10.1074/jbc.m109.032706 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038959519
400 rdf:type schema:CreativeWork
401 https://doi.org/10.1074/jbc.m109.072132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006176505
402 rdf:type schema:CreativeWork
403 https://doi.org/10.1074/jbc.m110.161117 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007008696
404 rdf:type schema:CreativeWork
405 https://doi.org/10.1074/jbc.m110.164293 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043438169
406 rdf:type schema:CreativeWork
407 https://doi.org/10.1074/jbc.m114.602771 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047854812
408 rdf:type schema:CreativeWork
409 https://doi.org/10.1074/jbc.m802115200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053277690
410 rdf:type schema:CreativeWork
411 https://doi.org/10.1093/bioinformatics/16.7.660 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047230091
412 rdf:type schema:CreativeWork
413 https://doi.org/10.1093/bioinformatics/btl529 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019858005
414 rdf:type schema:CreativeWork
415 https://doi.org/10.1093/gbe/evu132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020610574
416 rdf:type schema:CreativeWork
417 https://doi.org/10.1093/molbev/msp077 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028540883
418 rdf:type schema:CreativeWork
419 https://doi.org/10.1093/molbev/msw054 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012564990
420 rdf:type schema:CreativeWork
421 https://doi.org/10.1093/nar/gkn072 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038133966
422 rdf:type schema:CreativeWork
423 https://doi.org/10.1093/nar/gkt1183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047265540
424 rdf:type schema:CreativeWork
425 https://doi.org/10.1093/nar/gkt1223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010707975
426 rdf:type schema:CreativeWork
427 https://doi.org/10.1093/oxfordjournals.jbchem.a021870 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059960672
428 rdf:type schema:CreativeWork
429 https://doi.org/10.1093/oxfordjournals.molbev.a040023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082762864
430 rdf:type schema:CreativeWork
431 https://doi.org/10.1093/oxfordjournals.molbev.a040471 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079778351
432 rdf:type schema:CreativeWork
433 https://doi.org/10.1098/rstb.2012.0426 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053293689
434 rdf:type schema:CreativeWork
435 https://doi.org/10.1098/rstb.2012.0428 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020638296
436 rdf:type schema:CreativeWork
437 https://doi.org/10.1098/rstb.2012.0430 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021983247
438 rdf:type schema:CreativeWork
439 https://doi.org/10.1098/rstb.2012.0476 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014680783
440 rdf:type schema:CreativeWork
441 https://doi.org/10.1101/gr.8.12.1233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083369515
442 rdf:type schema:CreativeWork
443 https://doi.org/10.1104/pp.110.155119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013244354
444 rdf:type schema:CreativeWork
445 https://doi.org/10.1128/jb.00286-06 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009163899
446 rdf:type schema:CreativeWork
447 https://doi.org/10.1128/mmbr.00005-07 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039013531
448 rdf:type schema:CreativeWork
449 https://doi.org/10.1146/annurev-arplant-042809-112305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009024759
450 rdf:type schema:CreativeWork
451 https://doi.org/10.1371/journal.pcbi.1002195 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001034143
452 rdf:type schema:CreativeWork
453 https://doi.org/10.1371/journal.pone.0086683 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011461425
454 rdf:type schema:CreativeWork
455 https://doi.org/10.1371/journal.pone.0095616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014270316
456 rdf:type schema:CreativeWork
457 https://doi.org/10.1371/journal.pone.0100059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027740752
458 rdf:type schema:CreativeWork
459 https://doi.org/10.1371/journal.pone.0107209 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036753549
460 rdf:type schema:CreativeWork
461 https://doi.org/10.1371/journal.pone.0142100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005723925
462 rdf:type schema:CreativeWork
463 https://doi.org/10.1556/amicr.58.2011.3.4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067879378
464 rdf:type schema:CreativeWork
465 https://doi.org/10.3852/13-002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017279706
466 rdf:type schema:CreativeWork
467 https://www.grid.ac/institutes/grid.14003.36 schema:alternateName University of Wisconsin–Madison
468 schema:name Department of Bacteriology, University of Wisconsin-Madison, 3155 MSB, 1550 Linden Drive, Madison WI 53706, USA.
469 rdf:type schema:Organization
470 https://www.grid.ac/institutes/grid.17089.37 schema:alternateName University of Alberta
471 schema:name Department of Medical Microbiology and Immunology, 6-020 Katz Group Centre, University of Alberta, Edmonton, Alberta T6G 2E1, Canada.
472 Department of Physics, University of Alberta, Edmonton, Alberta T6G 2J1, Canada.
473 rdf:type schema:Organization
474 https://www.grid.ac/institutes/grid.267301.1 schema:alternateName University of Tennessee Health Science Center
475 schema:name Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
476 rdf:type schema:Organization
477 https://www.grid.ac/institutes/grid.35155.37 schema:alternateName Huazhong Agricultural University
478 schema:name College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei Province, China.
479 College of Informatics, Huazhong Agricultural University, Wuhan, Hubei Province, China.
480 rdf:type schema:Organization
481 https://www.grid.ac/institutes/grid.412219.d schema:alternateName University of the Free State
482 schema:name Faculty of Natural and Agricultural Science, Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, P.O. Box 339, Bloemfontein, 9300, South Africa.
483 rdf:type schema:Organization
484 https://www.grid.ac/institutes/grid.428369.2 schema:alternateName Central University of Technology
485 schema:name Unit for Drug Discovery Research, Department of Health Sciences, Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein 9300, Free State, South Africa.
486 rdf:type schema:Organization
487 https://www.grid.ac/institutes/grid.7836.a schema:alternateName University of Cape Town
488 schema:name Institute of Infectious Disease &Molecular Medicine; Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.
489 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...