Ontology type: schema:ScholarlyArticle Open Access: True
2016-07
AUTHORSSamuel Jourdan, Isolde Maria Francis, Min Jung Kim, Joren Jeico C Salazar, Sören Planckaert, Jean-Marie Frère, André Matagne, Frédéric Kerff, Bart Devreese, Rosemary Loria, Sébastien Rigali
ABSTRACTStreptomyces scabies is an economically important plant pathogen well-known for damaging root and tuber crops by causing scab lesions. Thaxtomin A is the main causative agent responsible for the pathogenicity of S. scabies and cello-oligosaccharides are environmental triggers that induce the production of this phytotoxin. How cello-oligosaccharides are sensed or transported in order to induce the virulent behavior of S. scabies? Here we report that the cellobiose and cellotriose binding protein CebE, and MsiK, the ATPase providing energy for carbohydrates transport, are the protagonists of the cello-oligosaccharide mediated induction of thaxtomin production in S. scabies. Our work provides the first example where the transport and not the sensing of major constituents of the plant host is the central mechanism associated with virulence of the pathogen. Our results allow to draw a complete pathway from signal transport to phytotoxin production where each step of the cascade is controlled by CebR, the cellulose utilization regulator. We propose the high affinity of CebE to cellotriose as possible adaptation of S. scabies to colonize expanding plant tissue. Our work further highlights how genes associated with primary metabolism in nonpathogenic Streptomyces species have been recruited as basic elements of virulence in plant pathogenic species. More... »
PAGES27144
http://scigraph.springernature.com/pub.10.1038/srep27144
DOIhttp://dx.doi.org/10.1038/srep27144
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/27250236
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]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101563288"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/srep27144"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1034888755"
]
}
],
"sameAs": [
"https://doi.org/10.1038/srep27144",
"https://app.dimensions.ai/details/publication/pub.1034888755"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T02:19",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000550.jsonl",
"type": "ScholarlyArticle",
"url": "http://www.nature.com/srep/2016/160602/srep27144/full/srep27144.html"
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]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/srep27144'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/srep27144'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/srep27144'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/srep27144'
This table displays all metadata directly associated to this object as RDF triples.
336 TRIPLES
21 PREDICATES
86 URIs
35 LITERALS
23 BLANK NODES