Anemia increases the mortality risk in patients with stroke: A meta-analysis of cohort studies View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-07

AUTHORS

Zhanzhan Li, Tao Zhou, Yanyan Li, Peng Chen, Lizhang Chen

ABSTRACT

The impact of anemia on the outcome of patients with stroke remains inconsistent. We performed a meta-analysis of cohort studies to assess the mortality risk in stroke patients with and without anemia. Systematic searches were conducted in the PubMed, China National Knowledge Infrastructure, Web of Science and Wanfang databases to identify relevant studies from inception to November 2015. The estimated odds ratio with a 95% confidence interval was pooled. subgroup analyses and sensitivity analyses were also conducted. We used Begg's funnel plot and Egger's test to detect the potential publication bias. Thirteen cohort studies with a total of 19239 patients with stroke were included in this meta-analysis. The heterogeneity among studies was slight (I(2) = 59.0%, P = 0.031). The results from a random-effect model suggest that anemia is associated with an increased mortality risk in patients with stroke (adjusted odds ratio = 1.39, 95% confidence interval: 1.22-1.58, P < 0.001). The subgroup analyses are consistent with the total results. This meta-analysis of 13 cohort studies finds that anemia increases the mortality risk in patients with stroke. Future studies should perform longer follow-up to confirm this finding and explore its possible mechanism. More... »

PAGES

26636

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/srep26636

DOI

http://dx.doi.org/10.1038/srep26636

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006883104

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27211606


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anemia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cohort Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease-Free Survival", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Stroke", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Li", 
        "givenName": "Zhanzhan", 
        "id": "sg:person.0735572732.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735572732.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhou", 
        "givenName": "Tao", 
        "id": "sg:person.01307261264.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307261264.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Third Affiliated Hospital of Southern Medical University", 
          "id": "https://www.grid.ac/institutes/grid.413107.0", 
          "name": [
            "The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guandong Province 510000, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Li", 
        "givenName": "Yanyan", 
        "id": "sg:person.01003706132.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003706132.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of orthopedic, Xiangya Hospital, Central-south University, Changsha, Hunan Province 410008, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "Peng", 
        "id": "sg:person.01120134532.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120134532.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central South University", 
          "id": "https://www.grid.ac/institutes/grid.216417.7", 
          "name": [
            "Department of Epidemiology and Health Statistics, School of public health, Central South University, Changsha, Hunan Province 410078, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "Lizhang", 
        "id": "sg:person.01355332045.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01355332045.33"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1111/ijs.12397", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003256479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/ijs.12397", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003256479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/ijs.12397", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003256479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mcc.0b013e3282f57577", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003616787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mcc.0b013e3282f57577", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003616787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mcc.0b013e3282f57577", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003616787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjcard.2006.03.031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004714369"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.327.7414.557", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005003882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bcmd.2009.02.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005112802"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ndt/gfq748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009416882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjmed.2005.06.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011467628"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjmed.2005.06.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011467628"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/jhh.2015.22", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012668765", 
          "https://doi.org/10.1038/jhh.2015.22"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31819ced3a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014065012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31819ced3a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014065012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31819ced3a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014065012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gerona/gls121", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014631911"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/nu6125915", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015952028"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.114.001645", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019155359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.114.001645", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019155359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1468-1331.2006.01591.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019295049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.283.15.2008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023723086"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2377-10-22", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025636194", 
          "https://doi.org/10.1186/1471-2377-10-22"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11239-005-1377-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025745251", 
          "https://doi.org/10.1007/s11239-005-1377-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jocn.2008.08.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028623034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neurobiolaging.2014.12.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028986251"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/ane.12521", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033294131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-2456(86)90046-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034546744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-2456(86)90046-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034546744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1590/s0034-8910.2014048005039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040626869"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.str.32.4.917", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041627736"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40064-015-1001-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041704567", 
          "https://doi.org/10.1186/s40064-015-1001-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40064-015-1001-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041704567", 
          "https://doi.org/10.1186/s40064-015-1001-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jstrokecerebrovasdis.2011.09.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042336011"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000334723", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042750695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2369-11-27", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042794370", 
          "https://doi.org/10.1186/1471-2369-11-27"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.str.32.1.280", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043063840"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4103/0028-3886.41996", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044167066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/strokeaha.109.556159", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045600065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/strokeaha.109.556159", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045600065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mca.0b013e3283472ac5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046964754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mca.0b013e3283472ac5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046964754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1253/circj.cj-15-0852", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047021346"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.str.31.10.2325", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048552857"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jocn.2012.05.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049412863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1474-4422(15)00132-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049593783"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jgs.13685", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051055367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9343(02)01498-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052742291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.315.7109.629", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062780726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.315.7109.629", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062780726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.str.28.6.1233", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063342401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/strokeaha.115.010954", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063345608"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/strokeaha.115.010954", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063345608"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/2533446", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069978841"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.6004/jnccn.2015.0152", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079166862"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.6004/jnccn.2015.0152", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079166862"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-07", 
    "datePublishedReg": "2016-07-01", 
    "description": "The impact of anemia on the outcome of patients with stroke remains inconsistent. We performed a meta-analysis of cohort studies to assess the mortality risk in stroke patients with and without anemia. Systematic searches were conducted in the PubMed, China National Knowledge Infrastructure, Web of Science and Wanfang databases to identify relevant studies from inception to November 2015. The estimated odds ratio with a 95% confidence interval was pooled. subgroup analyses and sensitivity analyses were also conducted. We used Begg's funnel plot and Egger's test to detect the potential publication bias. Thirteen cohort studies with a total of 19239 patients with stroke were included in this meta-analysis. The heterogeneity among studies was slight (I(2)\u2009=\u200959.0%, P\u2009=\u20090.031). The results from a random-effect model suggest that anemia is associated with an increased mortality risk in patients with stroke (adjusted odds ratio\u2009=\u20091.39, 95% confidence interval: 1.22-1.58, P\u2009<\u20090.001). The subgroup analyses are consistent with the total results. This meta-analysis of 13 cohort studies finds that anemia increases the mortality risk in patients with stroke. Future studies should perform longer follow-up to confirm this finding and explore its possible mechanism.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/srep26636", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1045337", 
        "issn": [
          "2045-2322"
        ], 
        "name": "Scientific Reports", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "name": "Anemia increases the mortality risk in patients with stroke: A meta-analysis of cohort studies", 
    "pagination": "26636", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "20c9986a991f9b390a275df0a1a2a9ca17f3d488778992509687409f9d9a40e1"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27211606"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101563288"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/srep26636"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1006883104"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/srep26636", 
      "https://app.dimensions.ai/details/publication/pub.1006883104"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T22:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8690_00000549.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/srep/2016/160523/srep26636/full/srep26636.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/srep26636'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/srep26636'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/srep26636'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/srep26636'


 

This table displays all metadata directly associated to this object as RDF triples.

269 TRIPLES      21 PREDICATES      79 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/srep26636 schema:about N14e24feb0a1740a6b96653ac252c7ad8
2 N4bba9f4aba9b41b8b08443797e134b3b
3 N532fec17d50b45e99f455747ee2a9a54
4 N5f509e9b14744884996ea7ef2cb4e7c3
5 N674c97df3843405ba05c2467e25e5304
6 Nd395c8bd5ab84358ba27928148caedd4
7 Nd474dceb6d1a4e52a041dbdb6e67b848
8 Nde924211775047cba3b605a0c4f676e0
9 Nf7a99e45c4a44cfba817d7b2f865fb0c
10 anzsrc-for:11
11 anzsrc-for:1117
12 schema:author Naf8e442367fe416d85072169a0115ae1
13 schema:citation sg:pub.10.1007/s11239-005-1377-7
14 sg:pub.10.1038/jhh.2015.22
15 sg:pub.10.1186/1471-2369-11-27
16 sg:pub.10.1186/1471-2377-10-22
17 sg:pub.10.1186/s40064-015-1001-z
18 https://doi.org/10.1001/jama.283.15.2008
19 https://doi.org/10.1016/0197-2456(86)90046-2
20 https://doi.org/10.1016/j.amjcard.2006.03.031
21 https://doi.org/10.1016/j.amjmed.2005.06.039
22 https://doi.org/10.1016/j.bcmd.2009.02.007
23 https://doi.org/10.1016/j.jocn.2008.08.014
24 https://doi.org/10.1016/j.jocn.2012.05.020
25 https://doi.org/10.1016/j.jstrokecerebrovasdis.2011.09.003
26 https://doi.org/10.1016/j.neurobiolaging.2014.12.019
27 https://doi.org/10.1016/s0002-9343(02)01498-5
28 https://doi.org/10.1016/s1474-4422(15)00132-5
29 https://doi.org/10.1093/gerona/gls121
30 https://doi.org/10.1093/ndt/gfq748
31 https://doi.org/10.1097/ccm.0b013e31819ced3a
32 https://doi.org/10.1097/mca.0b013e3283472ac5
33 https://doi.org/10.1097/mcc.0b013e3282f57577
34 https://doi.org/10.1111/ane.12521
35 https://doi.org/10.1111/ijs.12397
36 https://doi.org/10.1111/j.1468-1331.2006.01591.x
37 https://doi.org/10.1111/jgs.13685
38 https://doi.org/10.1136/bmj.315.7109.629
39 https://doi.org/10.1136/bmj.327.7414.557
40 https://doi.org/10.1159/000334723
41 https://doi.org/10.1161/01.str.28.6.1233
42 https://doi.org/10.1161/01.str.31.10.2325
43 https://doi.org/10.1161/01.str.32.1.280
44 https://doi.org/10.1161/01.str.32.4.917
45 https://doi.org/10.1161/circheartfailure.114.001645
46 https://doi.org/10.1161/strokeaha.109.556159
47 https://doi.org/10.1161/strokeaha.115.010954
48 https://doi.org/10.1253/circj.cj-15-0852
49 https://doi.org/10.1590/s0034-8910.2014048005039
50 https://doi.org/10.2307/2533446
51 https://doi.org/10.3390/nu6125915
52 https://doi.org/10.4103/0028-3886.41996
53 https://doi.org/10.6004/jnccn.2015.0152
54 schema:datePublished 2016-07
55 schema:datePublishedReg 2016-07-01
56 schema:description The impact of anemia on the outcome of patients with stroke remains inconsistent. We performed a meta-analysis of cohort studies to assess the mortality risk in stroke patients with and without anemia. Systematic searches were conducted in the PubMed, China National Knowledge Infrastructure, Web of Science and Wanfang databases to identify relevant studies from inception to November 2015. The estimated odds ratio with a 95% confidence interval was pooled. subgroup analyses and sensitivity analyses were also conducted. We used Begg's funnel plot and Egger's test to detect the potential publication bias. Thirteen cohort studies with a total of 19239 patients with stroke were included in this meta-analysis. The heterogeneity among studies was slight (I(2) = 59.0%, P = 0.031). The results from a random-effect model suggest that anemia is associated with an increased mortality risk in patients with stroke (adjusted odds ratio = 1.39, 95% confidence interval: 1.22-1.58, P < 0.001). The subgroup analyses are consistent with the total results. This meta-analysis of 13 cohort studies finds that anemia increases the mortality risk in patients with stroke. Future studies should perform longer follow-up to confirm this finding and explore its possible mechanism.
57 schema:genre research_article
58 schema:inLanguage en
59 schema:isAccessibleForFree true
60 schema:isPartOf N0702871a9a7e417686fca09ffda9d117
61 N4f7c1974f41d447c81302f46a2eee660
62 sg:journal.1045337
63 schema:name Anemia increases the mortality risk in patients with stroke: A meta-analysis of cohort studies
64 schema:pagination 26636
65 schema:productId N4d3eafe89ef84b678d8ed9bb5a5169c3
66 N9112bec106ff4ddca59455e454223eec
67 Nb60f187f2c3f4df1aa3f5922d2a5b02f
68 Nb9648d8234ea4aa18e42212f9e94b2cd
69 Ncaf48da533c24c0e9b9cb4e77da91f2e
70 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006883104
71 https://doi.org/10.1038/srep26636
72 schema:sdDatePublished 2019-04-10T22:39
73 schema:sdLicense https://scigraph.springernature.com/explorer/license/
74 schema:sdPublisher Nf1a4c84d9f5b41ed90af7b79e9e9214b
75 schema:url http://www.nature.com/srep/2016/160523/srep26636/full/srep26636.html
76 sgo:license sg:explorer/license/
77 sgo:sdDataset articles
78 rdf:type schema:ScholarlyArticle
79 N0702871a9a7e417686fca09ffda9d117 schema:issueNumber 1
80 rdf:type schema:PublicationIssue
81 N133e9884042f4996820fe5324164ffc8 schema:name Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, China.
82 rdf:type schema:Organization
83 N14e24feb0a1740a6b96653ac252c7ad8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Stroke
85 rdf:type schema:DefinedTerm
86 N204392b8b04d4ed6b7f535a3db4fc969 rdf:first sg:person.01307261264.38
87 rdf:rest Nd17912d310a8488a9accca27cb82ceb3
88 N38cad98c0763403cb938919b5d30aebb rdf:first sg:person.01120134532.53
89 rdf:rest N49bfdfe808c843a2b976f85d1e520917
90 N49bfdfe808c843a2b976f85d1e520917 rdf:first sg:person.01355332045.33
91 rdf:rest rdf:nil
92 N4bba9f4aba9b41b8b08443797e134b3b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Cohort Studies
94 rdf:type schema:DefinedTerm
95 N4d3eafe89ef84b678d8ed9bb5a5169c3 schema:name readcube_id
96 schema:value 20c9986a991f9b390a275df0a1a2a9ca17f3d488778992509687409f9d9a40e1
97 rdf:type schema:PropertyValue
98 N4f7c1974f41d447c81302f46a2eee660 schema:volumeNumber 6
99 rdf:type schema:PublicationVolume
100 N532fec17d50b45e99f455747ee2a9a54 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Female
102 rdf:type schema:DefinedTerm
103 N5f509e9b14744884996ea7ef2cb4e7c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Male
105 rdf:type schema:DefinedTerm
106 N674c97df3843405ba05c2467e25e5304 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Survival Rate
108 rdf:type schema:DefinedTerm
109 N9112bec106ff4ddca59455e454223eec schema:name dimensions_id
110 schema:value pub.1006883104
111 rdf:type schema:PropertyValue
112 Naf8e442367fe416d85072169a0115ae1 rdf:first sg:person.0735572732.56
113 rdf:rest N204392b8b04d4ed6b7f535a3db4fc969
114 Nb60f187f2c3f4df1aa3f5922d2a5b02f schema:name doi
115 schema:value 10.1038/srep26636
116 rdf:type schema:PropertyValue
117 Nb9648d8234ea4aa18e42212f9e94b2cd schema:name nlm_unique_id
118 schema:value 101563288
119 rdf:type schema:PropertyValue
120 Nc56192db654f4603ae2cf1fb0243f502 schema:name Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, China.
121 rdf:type schema:Organization
122 Ncaf48da533c24c0e9b9cb4e77da91f2e schema:name pubmed_id
123 schema:value 27211606
124 rdf:type schema:PropertyValue
125 Nd17912d310a8488a9accca27cb82ceb3 rdf:first sg:person.01003706132.24
126 rdf:rest N38cad98c0763403cb938919b5d30aebb
127 Nd395c8bd5ab84358ba27928148caedd4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Disease-Free Survival
129 rdf:type schema:DefinedTerm
130 Nd474dceb6d1a4e52a041dbdb6e67b848 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Anemia
132 rdf:type schema:DefinedTerm
133 Nde924211775047cba3b605a0c4f676e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Risk Factors
135 rdf:type schema:DefinedTerm
136 Nf1a4c84d9f5b41ed90af7b79e9e9214b schema:name Springer Nature - SN SciGraph project
137 rdf:type schema:Organization
138 Nf7a99e45c4a44cfba817d7b2f865fb0c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Humans
140 rdf:type schema:DefinedTerm
141 Nfb350bfaa98e4e42a6594d3b1a20e536 schema:name Department of orthopedic, Xiangya Hospital, Central-south University, Changsha, Hunan Province 410008, China.
142 rdf:type schema:Organization
143 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
144 schema:name Medical and Health Sciences
145 rdf:type schema:DefinedTerm
146 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
147 schema:name Public Health and Health Services
148 rdf:type schema:DefinedTerm
149 sg:journal.1045337 schema:issn 2045-2322
150 schema:name Scientific Reports
151 rdf:type schema:Periodical
152 sg:person.01003706132.24 schema:affiliation https://www.grid.ac/institutes/grid.413107.0
153 schema:familyName Li
154 schema:givenName Yanyan
155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003706132.24
156 rdf:type schema:Person
157 sg:person.01120134532.53 schema:affiliation Nfb350bfaa98e4e42a6594d3b1a20e536
158 schema:familyName Chen
159 schema:givenName Peng
160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120134532.53
161 rdf:type schema:Person
162 sg:person.01307261264.38 schema:affiliation N133e9884042f4996820fe5324164ffc8
163 schema:familyName Zhou
164 schema:givenName Tao
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307261264.38
166 rdf:type schema:Person
167 sg:person.01355332045.33 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
168 schema:familyName Chen
169 schema:givenName Lizhang
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01355332045.33
171 rdf:type schema:Person
172 sg:person.0735572732.56 schema:affiliation Nc56192db654f4603ae2cf1fb0243f502
173 schema:familyName Li
174 schema:givenName Zhanzhan
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735572732.56
176 rdf:type schema:Person
177 sg:pub.10.1007/s11239-005-1377-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025745251
178 https://doi.org/10.1007/s11239-005-1377-7
179 rdf:type schema:CreativeWork
180 sg:pub.10.1038/jhh.2015.22 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012668765
181 https://doi.org/10.1038/jhh.2015.22
182 rdf:type schema:CreativeWork
183 sg:pub.10.1186/1471-2369-11-27 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042794370
184 https://doi.org/10.1186/1471-2369-11-27
185 rdf:type schema:CreativeWork
186 sg:pub.10.1186/1471-2377-10-22 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025636194
187 https://doi.org/10.1186/1471-2377-10-22
188 rdf:type schema:CreativeWork
189 sg:pub.10.1186/s40064-015-1001-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1041704567
190 https://doi.org/10.1186/s40064-015-1001-z
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1001/jama.283.15.2008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023723086
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1016/0197-2456(86)90046-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034546744
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1016/j.amjcard.2006.03.031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004714369
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/j.amjmed.2005.06.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011467628
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/j.bcmd.2009.02.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005112802
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1016/j.jocn.2008.08.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028623034
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1016/j.jocn.2012.05.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049412863
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/j.jstrokecerebrovasdis.2011.09.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042336011
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/j.neurobiolaging.2014.12.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028986251
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/s0002-9343(02)01498-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052742291
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/s1474-4422(15)00132-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049593783
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1093/gerona/gls121 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014631911
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1093/ndt/gfq748 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009416882
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1097/ccm.0b013e31819ced3a schema:sameAs https://app.dimensions.ai/details/publication/pub.1014065012
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1097/mca.0b013e3283472ac5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046964754
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1097/mcc.0b013e3282f57577 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003616787
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1111/ane.12521 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033294131
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1111/ijs.12397 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003256479
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1111/j.1468-1331.2006.01591.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019295049
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1111/jgs.13685 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051055367
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1136/bmj.315.7109.629 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062780726
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1136/bmj.327.7414.557 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005003882
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1159/000334723 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042750695
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1161/01.str.28.6.1233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063342401
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1161/01.str.31.10.2325 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048552857
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1161/01.str.32.1.280 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043063840
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1161/01.str.32.4.917 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041627736
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1161/circheartfailure.114.001645 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019155359
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1161/strokeaha.109.556159 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045600065
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1161/strokeaha.115.010954 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063345608
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1253/circj.cj-15-0852 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047021346
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1590/s0034-8910.2014048005039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040626869
255 rdf:type schema:CreativeWork
256 https://doi.org/10.2307/2533446 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069978841
257 rdf:type schema:CreativeWork
258 https://doi.org/10.3390/nu6125915 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015952028
259 rdf:type schema:CreativeWork
260 https://doi.org/10.4103/0028-3886.41996 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044167066
261 rdf:type schema:CreativeWork
262 https://doi.org/10.6004/jnccn.2015.0152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079166862
263 rdf:type schema:CreativeWork
264 https://www.grid.ac/institutes/grid.216417.7 schema:alternateName Central South University
265 schema:name Department of Epidemiology and Health Statistics, School of public health, Central South University, Changsha, Hunan Province 410078, China.
266 rdf:type schema:Organization
267 https://www.grid.ac/institutes/grid.413107.0 schema:alternateName Third Affiliated Hospital of Southern Medical University
268 schema:name The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guandong Province 510000, China.
269 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...