Respiratory Syncytial Virus whole-genome sequencing identifies convergent evolution of sequence duplication in the C-terminus of the G gene View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-09

AUTHORS

Seth A. Schobel, Karla M. Stucker, Martin L. Moore, Larry J. Anderson, Emma K. Larkin, Jyoti Shankar, Jayati Bera, Vinita Puri, Meghan H. Shilts, Christian Rosas-Salazar, Rebecca A. Halpin, Nadia Fedorova, Susmita Shrivastava, Timothy B. Stockwell, R. Stokes Peebles, Tina V. Hartert, Suman R. Das

ABSTRACT

Respiratory Syncytial Virus (RSV) is responsible for considerable morbidity and mortality worldwide and is the most important respiratory viral pathogen in infants. Extensive sequence variability within and between RSV group A and B viruses and the ability of multiple clades and sub-clades of RSV to co-circulate are likely mechanisms contributing to the evasion of herd immunity. Surveillance and large-scale whole-genome sequencing of RSV is currently limited but would help identify its evolutionary dynamics and sites of selective immune evasion. In this study, we performed complete-genome next-generation sequencing of 92 RSV isolates from infants in central Tennessee during the 2012-2014 RSV seasons. We identified multiple co-circulating clades of RSV from both the A and B groups. Each clade is defined by signature N- and O-linked glycosylation patterns. Analyses of specific RSV genes revealed high rates of positive selection in the attachment (G) gene. We identified RSV-A viruses in circulation with and without a recently reported 72-nucleotide G gene sequence duplication. Furthermore, we show evidence of convergent evolution of G gene sequence duplication and fixation over time, which suggests a potential fitness advantage of RSV with the G sequence duplication. More... »

PAGES

26311

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/srep26311

DOI

http://dx.doi.org/10.1038/srep26311

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006173437

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27212633


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bayes Theorem", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Evolution, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Duplication", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glycosylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "High-Throughput Nucleotide Sequencing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Longitudinal Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phylogeny", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Repetitive Sequences, Nucleic Acid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Respiratory Syncytial Virus Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Respiratory Syncytial Virus, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Analysis, RNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tennessee", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Viral Envelope Proteins", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Maryland, College Park", 
          "id": "https://www.grid.ac/institutes/grid.164295.d", 
          "name": [
            "Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA", 
            "Bioinformatics Group, J. Craig Venter Institute, Rockville, MD, USA", 
            "Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schobel", 
        "givenName": "Seth A.", 
        "id": "sg:person.01340423310.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340423310.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "J. Craig Venter Institute", 
          "id": "https://www.grid.ac/institutes/grid.469946.0", 
          "name": [
            "Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stucker", 
        "givenName": "Karla M.", 
        "id": "sg:person.01245040657.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245040657.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Emory University", 
          "id": "https://www.grid.ac/institutes/grid.189967.8", 
          "name": [
            "Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine and Children\u2019s Healthcare of Atlanta, Atlanta, GA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moore", 
        "givenName": "Martin L.", 
        "id": "sg:person.012356447167.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012356447167.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Emory University", 
          "id": "https://www.grid.ac/institutes/grid.189967.8", 
          "name": [
            "Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine and Children\u2019s Healthcare of Atlanta, Atlanta, GA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Anderson", 
        "givenName": "Larry J.", 
        "id": "sg:person.01350151562.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350151562.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vanderbilt University", 
          "id": "https://www.grid.ac/institutes/grid.152326.1", 
          "name": [
            "Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA", 
            "Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Larkin", 
        "givenName": "Emma K.", 
        "id": "sg:person.01146512212.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146512212.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "J. Craig Venter Institute", 
          "id": "https://www.grid.ac/institutes/grid.469946.0", 
          "name": [
            "Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shankar", 
        "givenName": "Jyoti", 
        "id": "sg:person.01300071344.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300071344.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "J. Craig Venter Institute", 
          "id": "https://www.grid.ac/institutes/grid.469946.0", 
          "name": [
            "Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bera", 
        "givenName": "Jayati", 
        "id": "sg:person.01115035240.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115035240.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "J. Craig Venter Institute", 
          "id": "https://www.grid.ac/institutes/grid.469946.0", 
          "name": [
            "Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Puri", 
        "givenName": "Vinita", 
        "id": "sg:person.01145330207.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145330207.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "J. Craig Venter Institute", 
          "id": "https://www.grid.ac/institutes/grid.469946.0", 
          "name": [
            "Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shilts", 
        "givenName": "Meghan H.", 
        "id": "sg:person.01056757425.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056757425.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vanderbilt University", 
          "id": "https://www.grid.ac/institutes/grid.152326.1", 
          "name": [
            "Division of Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rosas-Salazar", 
        "givenName": "Christian", 
        "id": "sg:person.01152707575.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152707575.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "J. Craig Venter Institute", 
          "id": "https://www.grid.ac/institutes/grid.469946.0", 
          "name": [
            "Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Halpin", 
        "givenName": "Rebecca A.", 
        "id": "sg:person.01206005674.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01206005674.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "J. Craig Venter Institute", 
          "id": "https://www.grid.ac/institutes/grid.469946.0", 
          "name": [
            "Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fedorova", 
        "givenName": "Nadia", 
        "id": "sg:person.0763702526.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763702526.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "J. Craig Venter Institute", 
          "id": "https://www.grid.ac/institutes/grid.469946.0", 
          "name": [
            "Bioinformatics Group, J. Craig Venter Institute, Rockville, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shrivastava", 
        "givenName": "Susmita", 
        "id": "sg:person.0624157366.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624157366.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "J. Craig Venter Institute", 
          "id": "https://www.grid.ac/institutes/grid.469946.0", 
          "name": [
            "Bioinformatics Group, J. Craig Venter Institute, Rockville, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stockwell", 
        "givenName": "Timothy B.", 
        "id": "sg:person.01360521253.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360521253.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vanderbilt University", 
          "id": "https://www.grid.ac/institutes/grid.152326.1", 
          "name": [
            "Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA", 
            "Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Peebles", 
        "givenName": "R. Stokes", 
        "id": "sg:person.01366035015.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366035015.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vanderbilt University", 
          "id": "https://www.grid.ac/institutes/grid.152326.1", 
          "name": [
            "Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA", 
            "Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hartert", 
        "givenName": "Tina V.", 
        "id": "sg:person.01145642531.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145642531.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "J. Craig Venter Institute", 
          "id": "https://www.grid.ac/institutes/grid.469946.0", 
          "name": [
            "Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Das", 
        "givenName": "Suman R.", 
        "id": "sg:person.01045114174.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045114174.97"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1093/nar/gks528", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006038848"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-38919-1_4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006901967", 
          "https://doi.org/10.1007/978-3-642-38919-1_4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth.2109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007540814", 
          "https://doi.org/10.1038/nmeth.2109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.03391-14", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010400085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2148-7-214", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010584451", 
          "https://doi.org/10.1186/1471-2148-7-214"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmv.20456", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010897340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmv.20456", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010897340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12890-015-0040-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011035117", 
          "https://doi.org/10.1186/s12890-015-0040-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12890-015-0040-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011035117", 
          "https://doi.org/10.1186/s12890-015-0040-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.meegid.2013.09.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013165990"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/molbev/mss075", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013930907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(10)60206-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014462140"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1006960004440", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014575661", 
          "https://doi.org/10.1023/a:1006960004440"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.01045-15", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017724146"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2014/571609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019820693"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1743-422x-9-261", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021935369", 
          "https://doi.org/10.1186/1743-422x-9-261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.meegid.2007.08.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021987044"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmv.23425", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022816792"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/sysbio/syu031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023401909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cjs.5550360302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023764231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cjs.5550360302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023764231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.meegid.2014.07.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024211458"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.84.16.5625", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024402179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-38919-1_1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025908274", 
          "https://doi.org/10.1007/978-3-642-38919-1_1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-38919-1_2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027324735", 
          "https://doi.org/10.1007/978-3-642-38919-1_2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0032807", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032040563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0120098", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032138910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.02270-10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032742039"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0051439", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034737928"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1586/erp.12.45", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037896058"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.02571-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038158142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3201/eid1002.030759", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040366345"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0025468", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043159343"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3181/00379727-92-22538", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043176694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3181/00379727-92-22538", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043176694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3181/00379727-92-22538", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043176694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.80.2.975-984.2006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045010372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/molbev/mst010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045545793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/cmr.00032-09", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045700818"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.79.7.3962-3968.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046331319"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/genomea.00165-13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047899954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/cmr.13.1.1-15.2000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049700787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.03278-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051445815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-38919-1_3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052392327", 
          "https://doi.org/10.1007/978-3-642-38919-1_3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep14268", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053336879", 
          "https://doi.org/10.1038/srep14268"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/ped.2014.0463", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059305225"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/jgv.0.000298", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060389891"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/vir.0.19357-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060399998"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075670634", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077801157", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1109/gce.2010.5676129", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1094315180"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-09", 
    "datePublishedReg": "2016-09-01", 
    "description": "Respiratory Syncytial Virus (RSV) is responsible for considerable morbidity and mortality worldwide and is the most important respiratory viral pathogen in infants. Extensive sequence variability within and between RSV group A and B viruses and the ability of multiple clades and sub-clades of RSV to co-circulate are likely mechanisms contributing to the evasion of herd immunity. Surveillance and large-scale whole-genome sequencing of RSV is currently limited but would help identify its evolutionary dynamics and sites of selective immune evasion. In this study, we performed complete-genome next-generation sequencing of 92 RSV isolates from infants in central Tennessee during the 2012-2014 RSV seasons. We identified multiple co-circulating clades of RSV from both the A and B groups. Each clade is defined by signature N- and O-linked glycosylation patterns. Analyses of specific RSV genes revealed high rates of positive selection in the attachment (G) gene. We identified RSV-A viruses in circulation with and without a recently reported 72-nucleotide G gene sequence duplication. Furthermore, we show evidence of convergent evolution of G gene sequence duplication and fixation over time, which suggests a potential fitness advantage of RSV with the G sequence duplication.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/srep26311", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2695813", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2459334", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2695888", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2705238", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2420814", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3536102", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1045337", 
        "issn": [
          "2045-2322"
        ], 
        "name": "Scientific Reports", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "name": "Respiratory Syncytial Virus whole-genome sequencing identifies convergent evolution of sequence duplication in the C-terminus of the G gene", 
    "pagination": "26311", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "1d6867ca83f4e36cb637a2bc685706665cafb0d49372df53b93676217a3e034e"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27212633"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101563288"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/srep26311"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1006173437"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/srep26311", 
      "https://app.dimensions.ai/details/publication/pub.1006173437"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T02:18", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000549.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/srep26311"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/srep26311'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/srep26311'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/srep26311'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/srep26311'


 

This table displays all metadata directly associated to this object as RDF triples.

424 TRIPLES      21 PREDICATES      93 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/srep26311 schema:about N06183d0aaacf4916bbb34495b7a4f7c4
2 N0971db76f5b5474ca3b6007197bb44b9
3 N0a8f0f9088aa40a28299e03208419ef2
4 N221c0c86f2284cadad37283a6ddd3147
5 N30938c2988704dda830c453468089ef4
6 N46ae0d8b1bbf4bb280bde1142f48e774
7 N53076817fd344f1894864062ba038bd2
8 N62b3457a33a447d29e19ed78e7b6551c
9 N651afc3712a941a5916e673ef1bf66a8
10 N68b3277022fa4e04827496ac4bf9ea88
11 N8178b5cedbb140c1b7bf406ac41458d9
12 N8d37fec1f7fa4f55b7791c923126f14d
13 Nb1927f4cd0554fb19a3d7b252b295727
14 Nc283b13850354281b7a3af07e35ca4d4
15 Ncb6c8b816f86401b9b5bd44b462c4b74
16 Nd0732ceaf06c4e678d83b9724fb3902d
17 Nde8de958203e4acbaa6ba2482af3ee4f
18 Ne1cd2cb436ff41aa9e23cb0eef72c13b
19 anzsrc-for:06
20 anzsrc-for:0604
21 schema:author N1fa938193b8a401786cd82bd616084aa
22 schema:citation sg:pub.10.1007/978-3-642-38919-1_1
23 sg:pub.10.1007/978-3-642-38919-1_2
24 sg:pub.10.1007/978-3-642-38919-1_3
25 sg:pub.10.1007/978-3-642-38919-1_4
26 sg:pub.10.1023/a:1006960004440
27 sg:pub.10.1038/nmeth.2109
28 sg:pub.10.1038/srep14268
29 sg:pub.10.1186/1471-2148-7-214
30 sg:pub.10.1186/1743-422x-9-261
31 sg:pub.10.1186/s12890-015-0040-0
32 https://app.dimensions.ai/details/publication/pub.1075670634
33 https://app.dimensions.ai/details/publication/pub.1077801157
34 https://doi.org/10.1002/cjs.5550360302
35 https://doi.org/10.1002/jmv.20456
36 https://doi.org/10.1002/jmv.23425
37 https://doi.org/10.1016/j.meegid.2007.08.001
38 https://doi.org/10.1016/j.meegid.2013.09.025
39 https://doi.org/10.1016/j.meegid.2014.07.030
40 https://doi.org/10.1016/s0140-6736(10)60206-1
41 https://doi.org/10.1073/pnas.84.16.5625
42 https://doi.org/10.1089/ped.2014.0463
43 https://doi.org/10.1093/molbev/mss075
44 https://doi.org/10.1093/molbev/mst010
45 https://doi.org/10.1093/nar/gks528
46 https://doi.org/10.1093/sysbio/syu031
47 https://doi.org/10.1099/jgv.0.000298
48 https://doi.org/10.1099/vir.0.19357-0
49 https://doi.org/10.1109/gce.2010.5676129
50 https://doi.org/10.1128/cmr.00032-09
51 https://doi.org/10.1128/cmr.13.1.1-15.2000
52 https://doi.org/10.1128/genomea.00165-13
53 https://doi.org/10.1128/jcm.02270-10
54 https://doi.org/10.1128/jvi.01045-15
55 https://doi.org/10.1128/jvi.02571-12
56 https://doi.org/10.1128/jvi.03278-12
57 https://doi.org/10.1128/jvi.03391-14
58 https://doi.org/10.1128/jvi.79.7.3962-3968.2005
59 https://doi.org/10.1128/jvi.80.2.975-984.2006
60 https://doi.org/10.1155/2014/571609
61 https://doi.org/10.1371/journal.pone.0025468
62 https://doi.org/10.1371/journal.pone.0032807
63 https://doi.org/10.1371/journal.pone.0051439
64 https://doi.org/10.1371/journal.pone.0120098
65 https://doi.org/10.1586/erp.12.45
66 https://doi.org/10.3181/00379727-92-22538
67 https://doi.org/10.3201/eid1002.030759
68 schema:datePublished 2016-09
69 schema:datePublishedReg 2016-09-01
70 schema:description Respiratory Syncytial Virus (RSV) is responsible for considerable morbidity and mortality worldwide and is the most important respiratory viral pathogen in infants. Extensive sequence variability within and between RSV group A and B viruses and the ability of multiple clades and sub-clades of RSV to co-circulate are likely mechanisms contributing to the evasion of herd immunity. Surveillance and large-scale whole-genome sequencing of RSV is currently limited but would help identify its evolutionary dynamics and sites of selective immune evasion. In this study, we performed complete-genome next-generation sequencing of 92 RSV isolates from infants in central Tennessee during the 2012-2014 RSV seasons. We identified multiple co-circulating clades of RSV from both the A and B groups. Each clade is defined by signature N- and O-linked glycosylation patterns. Analyses of specific RSV genes revealed high rates of positive selection in the attachment (G) gene. We identified RSV-A viruses in circulation with and without a recently reported 72-nucleotide G gene sequence duplication. Furthermore, we show evidence of convergent evolution of G gene sequence duplication and fixation over time, which suggests a potential fitness advantage of RSV with the G sequence duplication.
71 schema:genre research_article
72 schema:inLanguage en
73 schema:isAccessibleForFree true
74 schema:isPartOf N1a9f4483f9604dfabaf13189d2e921a4
75 Naf83360706c34e338a553dafee0d91f0
76 sg:journal.1045337
77 schema:name Respiratory Syncytial Virus whole-genome sequencing identifies convergent evolution of sequence duplication in the C-terminus of the G gene
78 schema:pagination 26311
79 schema:productId N0b6f09fffa2d48f08a8e27f191c842c5
80 N73f318baac8440d9a54e7cf4ef96729e
81 N9160cd0d6b9140df971f494b929b634c
82 Nd27ad7f83daf4d329b26ea85f834e3a3
83 Ne0cbd4b703fc47feb37df41cca14f914
84 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006173437
85 https://doi.org/10.1038/srep26311
86 schema:sdDatePublished 2019-04-11T02:18
87 schema:sdLicense https://scigraph.springernature.com/explorer/license/
88 schema:sdPublisher Naa566481308347c9abc1c9b8769b31ea
89 schema:url http://www.nature.com/articles/srep26311
90 sgo:license sg:explorer/license/
91 sgo:sdDataset articles
92 rdf:type schema:ScholarlyArticle
93 N06183d0aaacf4916bbb34495b7a4f7c4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Evolution, Molecular
95 rdf:type schema:DefinedTerm
96 N0971db76f5b5474ca3b6007197bb44b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Gene Duplication
98 rdf:type schema:DefinedTerm
99 N098fa3f36e8b44db970a581459f07806 rdf:first sg:person.01300071344.61
100 rdf:rest N5f6c62cc7ea94b12ad553608226b870e
101 N0a8f0f9088aa40a28299e03208419ef2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Glycosylation
103 rdf:type schema:DefinedTerm
104 N0b6f09fffa2d48f08a8e27f191c842c5 schema:name pubmed_id
105 schema:value 27212633
106 rdf:type schema:PropertyValue
107 N1a9f4483f9604dfabaf13189d2e921a4 schema:issueNumber 1
108 rdf:type schema:PublicationIssue
109 N1fa938193b8a401786cd82bd616084aa rdf:first sg:person.01340423310.87
110 rdf:rest N36204fefa7a94641a746089ed73e7ee9
111 N221c0c86f2284cadad37283a6ddd3147 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Sequence Analysis, RNA
113 rdf:type schema:DefinedTerm
114 N2dbb9462d6ce43b08dd1bfdc9683ef10 rdf:first sg:person.01145330207.77
115 rdf:rest N93d676e667864adc8b11fde37bc03ce6
116 N2f7c99eb3e1d4d71b24cb76a63510d54 rdf:first sg:person.01360521253.20
117 rdf:rest Nf6c502bfaffa47998e497ceeddc9a600
118 N30938c2988704dda830c453468089ef4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Tennessee
120 rdf:type schema:DefinedTerm
121 N36204fefa7a94641a746089ed73e7ee9 rdf:first sg:person.01245040657.13
122 rdf:rest Ncf4a5bfc409a4144a8765d17526c847f
123 N46ae0d8b1bbf4bb280bde1142f48e774 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Genome, Viral
125 rdf:type schema:DefinedTerm
126 N4981ca7ccc9b4296a87261326ad40590 rdf:first sg:person.01045114174.97
127 rdf:rest rdf:nil
128 N4b2cbcf54e56479aad2919c853d272a4 rdf:first sg:person.01146512212.15
129 rdf:rest N098fa3f36e8b44db970a581459f07806
130 N53076817fd344f1894864062ba038bd2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Repetitive Sequences, Nucleic Acid
132 rdf:type schema:DefinedTerm
133 N5f6c62cc7ea94b12ad553608226b870e rdf:first sg:person.01115035240.87
134 rdf:rest N2dbb9462d6ce43b08dd1bfdc9683ef10
135 N62b3457a33a447d29e19ed78e7b6551c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Longitudinal Studies
137 rdf:type schema:DefinedTerm
138 N651afc3712a941a5916e673ef1bf66a8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Bayes Theorem
140 rdf:type schema:DefinedTerm
141 N68b3277022fa4e04827496ac4bf9ea88 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Humans
143 rdf:type schema:DefinedTerm
144 N73f318baac8440d9a54e7cf4ef96729e schema:name nlm_unique_id
145 schema:value 101563288
146 rdf:type schema:PropertyValue
147 N8178b5cedbb140c1b7bf406ac41458d9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Female
149 rdf:type schema:DefinedTerm
150 N8d2c4a37018f490fa1d6eb6ce0dbc974 rdf:first sg:person.01145642531.34
151 rdf:rest N4981ca7ccc9b4296a87261326ad40590
152 N8d37fec1f7fa4f55b7791c923126f14d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name High-Throughput Nucleotide Sequencing
154 rdf:type schema:DefinedTerm
155 N9160cd0d6b9140df971f494b929b634c schema:name doi
156 schema:value 10.1038/srep26311
157 rdf:type schema:PropertyValue
158 N93d676e667864adc8b11fde37bc03ce6 rdf:first sg:person.01056757425.91
159 rdf:rest Nb509bc943bcf46448387eebf97cf4673
160 Na8632b9c8f494ae0825164fa66824202 rdf:first sg:person.01206005674.46
161 rdf:rest Nc75d92ded26a413eba2c294858e02c8c
162 Naa566481308347c9abc1c9b8769b31ea schema:name Springer Nature - SN SciGraph project
163 rdf:type schema:Organization
164 Naf83360706c34e338a553dafee0d91f0 schema:volumeNumber 6
165 rdf:type schema:PublicationVolume
166 Nb1927f4cd0554fb19a3d7b252b295727 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Respiratory Syncytial Virus, Human
168 rdf:type schema:DefinedTerm
169 Nb509bc943bcf46448387eebf97cf4673 rdf:first sg:person.01152707575.07
170 rdf:rest Na8632b9c8f494ae0825164fa66824202
171 Nb6a25f1aaa6541f488b95fe3325ccb26 rdf:first sg:person.0624157366.32
172 rdf:rest N2f7c99eb3e1d4d71b24cb76a63510d54
173 Nc283b13850354281b7a3af07e35ca4d4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Male
175 rdf:type schema:DefinedTerm
176 Nc75d92ded26a413eba2c294858e02c8c rdf:first sg:person.0763702526.67
177 rdf:rest Nb6a25f1aaa6541f488b95fe3325ccb26
178 Ncb6c8b816f86401b9b5bd44b462c4b74 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Infant
180 rdf:type schema:DefinedTerm
181 Ncf4a5bfc409a4144a8765d17526c847f rdf:first sg:person.012356447167.08
182 rdf:rest Nfc7ba89264bd449481b9450d2090e451
183 Nd0732ceaf06c4e678d83b9724fb3902d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
184 schema:name Respiratory Syncytial Virus Infections
185 rdf:type schema:DefinedTerm
186 Nd27ad7f83daf4d329b26ea85f834e3a3 schema:name readcube_id
187 schema:value 1d6867ca83f4e36cb637a2bc685706665cafb0d49372df53b93676217a3e034e
188 rdf:type schema:PropertyValue
189 Nde8de958203e4acbaa6ba2482af3ee4f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
190 schema:name Viral Envelope Proteins
191 rdf:type schema:DefinedTerm
192 Ne0cbd4b703fc47feb37df41cca14f914 schema:name dimensions_id
193 schema:value pub.1006173437
194 rdf:type schema:PropertyValue
195 Ne1cd2cb436ff41aa9e23cb0eef72c13b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
196 schema:name Phylogeny
197 rdf:type schema:DefinedTerm
198 Nf6c502bfaffa47998e497ceeddc9a600 rdf:first sg:person.01366035015.75
199 rdf:rest N8d2c4a37018f490fa1d6eb6ce0dbc974
200 Nfc7ba89264bd449481b9450d2090e451 rdf:first sg:person.01350151562.11
201 rdf:rest N4b2cbcf54e56479aad2919c853d272a4
202 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
203 schema:name Biological Sciences
204 rdf:type schema:DefinedTerm
205 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
206 schema:name Genetics
207 rdf:type schema:DefinedTerm
208 sg:grant.2420814 http://pending.schema.org/fundedItem sg:pub.10.1038/srep26311
209 rdf:type schema:MonetaryGrant
210 sg:grant.2459334 http://pending.schema.org/fundedItem sg:pub.10.1038/srep26311
211 rdf:type schema:MonetaryGrant
212 sg:grant.2695813 http://pending.schema.org/fundedItem sg:pub.10.1038/srep26311
213 rdf:type schema:MonetaryGrant
214 sg:grant.2695888 http://pending.schema.org/fundedItem sg:pub.10.1038/srep26311
215 rdf:type schema:MonetaryGrant
216 sg:grant.2705238 http://pending.schema.org/fundedItem sg:pub.10.1038/srep26311
217 rdf:type schema:MonetaryGrant
218 sg:grant.3536102 http://pending.schema.org/fundedItem sg:pub.10.1038/srep26311
219 rdf:type schema:MonetaryGrant
220 sg:journal.1045337 schema:issn 2045-2322
221 schema:name Scientific Reports
222 rdf:type schema:Periodical
223 sg:person.01045114174.97 schema:affiliation https://www.grid.ac/institutes/grid.469946.0
224 schema:familyName Das
225 schema:givenName Suman R.
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045114174.97
227 rdf:type schema:Person
228 sg:person.01056757425.91 schema:affiliation https://www.grid.ac/institutes/grid.469946.0
229 schema:familyName Shilts
230 schema:givenName Meghan H.
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056757425.91
232 rdf:type schema:Person
233 sg:person.01115035240.87 schema:affiliation https://www.grid.ac/institutes/grid.469946.0
234 schema:familyName Bera
235 schema:givenName Jayati
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115035240.87
237 rdf:type schema:Person
238 sg:person.01145330207.77 schema:affiliation https://www.grid.ac/institutes/grid.469946.0
239 schema:familyName Puri
240 schema:givenName Vinita
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145330207.77
242 rdf:type schema:Person
243 sg:person.01145642531.34 schema:affiliation https://www.grid.ac/institutes/grid.152326.1
244 schema:familyName Hartert
245 schema:givenName Tina V.
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145642531.34
247 rdf:type schema:Person
248 sg:person.01146512212.15 schema:affiliation https://www.grid.ac/institutes/grid.152326.1
249 schema:familyName Larkin
250 schema:givenName Emma K.
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146512212.15
252 rdf:type schema:Person
253 sg:person.01152707575.07 schema:affiliation https://www.grid.ac/institutes/grid.152326.1
254 schema:familyName Rosas-Salazar
255 schema:givenName Christian
256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152707575.07
257 rdf:type schema:Person
258 sg:person.01206005674.46 schema:affiliation https://www.grid.ac/institutes/grid.469946.0
259 schema:familyName Halpin
260 schema:givenName Rebecca A.
261 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01206005674.46
262 rdf:type schema:Person
263 sg:person.012356447167.08 schema:affiliation https://www.grid.ac/institutes/grid.189967.8
264 schema:familyName Moore
265 schema:givenName Martin L.
266 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012356447167.08
267 rdf:type schema:Person
268 sg:person.01245040657.13 schema:affiliation https://www.grid.ac/institutes/grid.469946.0
269 schema:familyName Stucker
270 schema:givenName Karla M.
271 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01245040657.13
272 rdf:type schema:Person
273 sg:person.01300071344.61 schema:affiliation https://www.grid.ac/institutes/grid.469946.0
274 schema:familyName Shankar
275 schema:givenName Jyoti
276 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300071344.61
277 rdf:type schema:Person
278 sg:person.01340423310.87 schema:affiliation https://www.grid.ac/institutes/grid.164295.d
279 schema:familyName Schobel
280 schema:givenName Seth A.
281 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340423310.87
282 rdf:type schema:Person
283 sg:person.01350151562.11 schema:affiliation https://www.grid.ac/institutes/grid.189967.8
284 schema:familyName Anderson
285 schema:givenName Larry J.
286 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350151562.11
287 rdf:type schema:Person
288 sg:person.01360521253.20 schema:affiliation https://www.grid.ac/institutes/grid.469946.0
289 schema:familyName Stockwell
290 schema:givenName Timothy B.
291 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360521253.20
292 rdf:type schema:Person
293 sg:person.01366035015.75 schema:affiliation https://www.grid.ac/institutes/grid.152326.1
294 schema:familyName Peebles
295 schema:givenName R. Stokes
296 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366035015.75
297 rdf:type schema:Person
298 sg:person.0624157366.32 schema:affiliation https://www.grid.ac/institutes/grid.469946.0
299 schema:familyName Shrivastava
300 schema:givenName Susmita
301 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624157366.32
302 rdf:type schema:Person
303 sg:person.0763702526.67 schema:affiliation https://www.grid.ac/institutes/grid.469946.0
304 schema:familyName Fedorova
305 schema:givenName Nadia
306 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763702526.67
307 rdf:type schema:Person
308 sg:pub.10.1007/978-3-642-38919-1_1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025908274
309 https://doi.org/10.1007/978-3-642-38919-1_1
310 rdf:type schema:CreativeWork
311 sg:pub.10.1007/978-3-642-38919-1_2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027324735
312 https://doi.org/10.1007/978-3-642-38919-1_2
313 rdf:type schema:CreativeWork
314 sg:pub.10.1007/978-3-642-38919-1_3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052392327
315 https://doi.org/10.1007/978-3-642-38919-1_3
316 rdf:type schema:CreativeWork
317 sg:pub.10.1007/978-3-642-38919-1_4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006901967
318 https://doi.org/10.1007/978-3-642-38919-1_4
319 rdf:type schema:CreativeWork
320 sg:pub.10.1023/a:1006960004440 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014575661
321 https://doi.org/10.1023/a:1006960004440
322 rdf:type schema:CreativeWork
323 sg:pub.10.1038/nmeth.2109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007540814
324 https://doi.org/10.1038/nmeth.2109
325 rdf:type schema:CreativeWork
326 sg:pub.10.1038/srep14268 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053336879
327 https://doi.org/10.1038/srep14268
328 rdf:type schema:CreativeWork
329 sg:pub.10.1186/1471-2148-7-214 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010584451
330 https://doi.org/10.1186/1471-2148-7-214
331 rdf:type schema:CreativeWork
332 sg:pub.10.1186/1743-422x-9-261 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021935369
333 https://doi.org/10.1186/1743-422x-9-261
334 rdf:type schema:CreativeWork
335 sg:pub.10.1186/s12890-015-0040-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011035117
336 https://doi.org/10.1186/s12890-015-0040-0
337 rdf:type schema:CreativeWork
338 https://app.dimensions.ai/details/publication/pub.1075670634 schema:CreativeWork
339 https://app.dimensions.ai/details/publication/pub.1077801157 schema:CreativeWork
340 https://doi.org/10.1002/cjs.5550360302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023764231
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1002/jmv.20456 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010897340
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1002/jmv.23425 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022816792
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1016/j.meegid.2007.08.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021987044
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1016/j.meegid.2013.09.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013165990
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1016/j.meegid.2014.07.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024211458
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1016/s0140-6736(10)60206-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014462140
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1073/pnas.84.16.5625 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024402179
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1089/ped.2014.0463 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059305225
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1093/molbev/mss075 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013930907
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1093/molbev/mst010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045545793
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1093/nar/gks528 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006038848
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1093/sysbio/syu031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023401909
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1099/jgv.0.000298 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060389891
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1099/vir.0.19357-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060399998
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1109/gce.2010.5676129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1094315180
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1128/cmr.00032-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045700818
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1128/cmr.13.1.1-15.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049700787
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1128/genomea.00165-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047899954
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1128/jcm.02270-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032742039
379 rdf:type schema:CreativeWork
380 https://doi.org/10.1128/jvi.01045-15 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017724146
381 rdf:type schema:CreativeWork
382 https://doi.org/10.1128/jvi.02571-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038158142
383 rdf:type schema:CreativeWork
384 https://doi.org/10.1128/jvi.03278-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051445815
385 rdf:type schema:CreativeWork
386 https://doi.org/10.1128/jvi.03391-14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010400085
387 rdf:type schema:CreativeWork
388 https://doi.org/10.1128/jvi.79.7.3962-3968.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046331319
389 rdf:type schema:CreativeWork
390 https://doi.org/10.1128/jvi.80.2.975-984.2006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045010372
391 rdf:type schema:CreativeWork
392 https://doi.org/10.1155/2014/571609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019820693
393 rdf:type schema:CreativeWork
394 https://doi.org/10.1371/journal.pone.0025468 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043159343
395 rdf:type schema:CreativeWork
396 https://doi.org/10.1371/journal.pone.0032807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032040563
397 rdf:type schema:CreativeWork
398 https://doi.org/10.1371/journal.pone.0051439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034737928
399 rdf:type schema:CreativeWork
400 https://doi.org/10.1371/journal.pone.0120098 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032138910
401 rdf:type schema:CreativeWork
402 https://doi.org/10.1586/erp.12.45 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037896058
403 rdf:type schema:CreativeWork
404 https://doi.org/10.3181/00379727-92-22538 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043176694
405 rdf:type schema:CreativeWork
406 https://doi.org/10.3201/eid1002.030759 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040366345
407 rdf:type schema:CreativeWork
408 https://www.grid.ac/institutes/grid.152326.1 schema:alternateName Vanderbilt University
409 schema:name Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
410 Division of Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA.
411 Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
412 rdf:type schema:Organization
413 https://www.grid.ac/institutes/grid.164295.d schema:alternateName University of Maryland, College Park
414 schema:name Bioinformatics Group, J. Craig Venter Institute, Rockville, MD, USA
415 Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, USA
416 Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA
417 rdf:type schema:Organization
418 https://www.grid.ac/institutes/grid.189967.8 schema:alternateName Emory University
419 schema:name Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine and Children’s Healthcare of Atlanta, Atlanta, GA, USA
420 rdf:type schema:Organization
421 https://www.grid.ac/institutes/grid.469946.0 schema:alternateName J. Craig Venter Institute
422 schema:name Bioinformatics Group, J. Craig Venter Institute, Rockville, MD, USA
423 Infectious Diseases Group, J. Craig Venter Institute, Rockville, MD, USA
424 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...