Factors influencing the use of topical repellents: implications for the effectiveness of malaria elimination strategies View Full Text


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Article Info

DATE

2015-11-17

AUTHORS

Charlotte Gryseels, Sambunny Uk, Vincent Sluydts, Lies Durnez, Pisen Phoeuk, Sokha Suon, Srun Set, Somony Heng, Sovannaroth Siv, René Gerrets, Sochantha Tho, Marc Coosemans, Koen Peeters Grietens

ABSTRACT

In Cambodia, despite an impressive decline in prevalence over the last 10 years, malaria is still a public health problem in some parts of the country. This is partly due to vectors that bite early and outdoors reducing the effectiveness of measures such as Long-Lasting Insecticidal Nets. Repellents have been suggested as an additional control measure in such settings. As part of a cluster-randomized trial on the effectiveness of topical repellents in controlling malaria infections at community level, a mixed-methods study assessed user rates and determinants of use. Repellents were made widely available and Picaridin repellent reduced 97% of mosquito bites. However, despite high acceptability, daily use was observed to be low (8%) and did not correspond to the reported use in surveys (around 70%). The levels of use aimed for by the trial were never reached as the population used it variably across place (forest, farms and villages) and time (seasons), or in alternative applications (spraying on insects, on bed nets, etc.). These findings show the key role of human behavior in the effectiveness of malaria preventive measures, questioning whether malaria in low endemic settings can be reduced substantially by introducing measures without researching and optimizing community involvement strategies. More... »

PAGES

16847

References to SciGraph publications

  • 2014-11-21. Are topical insect repellents effective against malaria in endemic populations? A systematic review and meta-analysis in MALARIA JOURNAL
  • 2007-07-03. The Hawthorne Effect: a randomised, controlled trial in BMC MEDICAL RESEARCH METHODOLOGY
  • 2014-09-02. Feasibility of repellent use in a context of increasing outdoor transmission: a qualitative study in rural Tanzania in MALARIA JOURNAL
  • 2012-01-04. Scale-up of community-based malaria control can be achieved without degrading community health workers' service quality: the Village Malaria Worker project in Cambodia in MALARIA JOURNAL
  • 2010-01-01. Genetic diversity among Plasmodium falciparum field isolates in Pakistan measured with PCR genotyping of the merozoite surface protein 1 and 2 in MALARIA JOURNAL
  • 2014-09-30. Spatial clustering and risk factors of malaria infections in Ratanakiri Province, Cambodia in MALARIA JOURNAL
  • 2010-01-20. Low perception of malaria risk among the Ra-glai ethnic minority in south-central Vietnam: implications for forest malaria control in MALARIA JOURNAL
  • 2015-04-24. Re-imagining malaria: heterogeneity of human and mosquito behaviour in relation to residual malaria transmission in Cambodia in MALARIA JOURNAL
  • 2012-05-14. Spatial repellents: from discovery and development to evidence-based validation in MALARIA JOURNAL
  • 2008-12-05. How did formative research inform the development of a women's group intervention in rural Nepal? in JOURNAL OF PERINATOLOGY
  • 2013-09-17. Outdoor malaria transmission in forested villages of Cambodia in MALARIA JOURNAL
  • 2006-07-27. Use of insecticide-treated clothes for personal protection against malaria: a community trial in MALARIA JOURNAL
  • 2014-03-28. Effect of combining mosquito repellent and insecticide treated net on malaria prevalence in Southern Ethiopia: a cluster-randomised trial in PARASITES & VECTORS
  • 2014-08-23. Characterizing, controlling and eliminating residual malaria transmission in MALARIA JOURNAL
  • 2008-01-30. Malaria in central Vietnam: analysis of risk factors by multivariate analysis and classification tree models in MALARIA JOURNAL
  • 2013-11-09. An innovative tool for moving malaria PCR detection of parasite reservoir into the field in MALARIA JOURNAL
  • 2011-08-04. The architecture and effect of participation: a systematic review of community participation for communicable disease control and elimination. Implications for malaria elimination in MALARIA JOURNAL
  • 2005-12-08. Epidemiology of forest malaria in central Vietnam: a large scale cross-sectional survey in MALARIA JOURNAL
  • 2014-08-16. A cluster-randomized controlled trial to assess the effectiveness of using 15% DEET topical repellent with long-lasting insecticidal nets (LLINs) compared to a placebo lotion on malaria transmission in MALARIA JOURNAL
  • Identifiers

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    http://scigraph.springernature.com/pub.10.1038/srep16847

    DOI

    http://dx.doi.org/10.1038/srep16847

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1040193159

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26574048


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