Tracking X-ray microscopy for alveolar dynamics in live intact mice View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-12

AUTHORS

Soeun Chang, Namseop Kwon, Byung Mook Weon, Jinkyung Kim, Chin Kook Rhee, Han Sung Choi, Yoshiki Kohmura, Masaki Yamamoto, Tetsuya Ishikawa, Jung Ho Je

ABSTRACT

Here we report a tracking X-ray microscopy (TrXM) as a novel methodology by using upper right lung apices alveoli in live intact mice. By enabling tracking of individual alveolar movements during respiration, TrXM identifies alveolar dynamics: individual alveoli in the upper lung apices show a small size increment as 4.9 ± 0.4% (mean ± s.e.m.) during respiration while their shapes look almost invariant. TrXM analysis in alveolar dynamics would be significant for better understanding of alveolar-based diseases, for instance, ventilator induced lung injury (VILI) in acute respiratory distress syndrome (ARDS). More... »

PAGES

1304

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/srep01304

DOI

http://dx.doi.org/10.1038/srep01304

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012616647

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23416838


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