Characteristics of sleep apnea syndrome in tetraplegic patients View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2002-06-05

AUTHORS

E Stockhammer, A Tobon, F Michel, P Eser, W Scheuler, W Bauer, M Baumberger, W Müller, TH Kakebeeke, H Knecht, GA Zäch

ABSTRACT

Objective: To include a larger number of tetraplegics than in previous studies, in order to more reliably characterize the pathogenesis and predisposing factors of sleep apnea in tetraplegia.Methods: Sleep breathing data and oxymetric values were investigated in 50 randomly selected tetraplegic patients and discussed in context with age, gender, BMI, neck circumference, type and height of lesion, time after injury, spirometric values and medication. A non-validated short questionnaire on daytime complaints was added.Results: Thirty-one patients out of 50 had an RDI ⩾15, defined as sleep disordered breathing (SDB); 24 of them combined with an apnea index of 5 or more, these cases were diagnosed as sleep apnea syndrome (SAS). SAS was apparent in 55% and 20% of the studied men and women, respectively. Regression analyses showed no significant correlation between RDI and lesion level, ASIA impairment scale or spirometric values. In contrast, a significant correlation between RDI and age, BMI, neck circumference and time after injury could be shown. Kruskal-Wallis test for dichotomous non-parametric factors, such as gender, cardiac medication and daytime complaints, showed significant differences with regard to RDI. In contrast to able-bodied people with SAS, daytime complaints were only present in tetraplegic patients with severe pathology (RDI>40).Conclusion: Incidence of SAS is high in tetraplegia, particularly in older male patients with large neck circumference, long standing spinal cord injury and under cardiac medication. As tetraplegics with RDI between 15 and 40 reported no daytime complaints and often have normal BMI, these tetraplegics are not clinically suspicious for SAS. The increased use of cardiac medication in tetraplegics with SAS may implicate a link between SAS and cardiovascular morbidity, one of the leading causes of death in tetraplegia. More... »

PAGES

286-294

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.sc.3101301

DOI

http://dx.doi.org/10.1038/sj.sc.3101301

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011561989

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12037710


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39 schema:description Objective: To include a larger number of tetraplegics than in previous studies, in order to more reliably characterize the pathogenesis and predisposing factors of sleep apnea in tetraplegia.Methods: Sleep breathing data and oxymetric values were investigated in 50 randomly selected tetraplegic patients and discussed in context with age, gender, BMI, neck circumference, type and height of lesion, time after injury, spirometric values and medication. A non-validated short questionnaire on daytime complaints was added.Results: Thirty-one patients out of 50 had an RDI ⩾15, defined as sleep disordered breathing (SDB); 24 of them combined with an apnea index of 5 or more, these cases were diagnosed as sleep apnea syndrome (SAS). SAS was apparent in 55% and 20% of the studied men and women, respectively. Regression analyses showed no significant correlation between RDI and lesion level, ASIA impairment scale or spirometric values. In contrast, a significant correlation between RDI and age, BMI, neck circumference and time after injury could be shown. Kruskal-Wallis test for dichotomous non-parametric factors, such as gender, cardiac medication and daytime complaints, showed significant differences with regard to RDI. In contrast to able-bodied people with SAS, daytime complaints were only present in tetraplegic patients with severe pathology (RDI>40).Conclusion: Incidence of SAS is high in tetraplegia, particularly in older male patients with large neck circumference, long standing spinal cord injury and under cardiac medication. As tetraplegics with RDI between 15 and 40 reported no daytime complaints and often have normal BMI, these tetraplegics are not clinically suspicious for SAS. The increased use of cardiac medication in tetraplegics with SAS may implicate a link between SAS and cardiovascular morbidity, one of the leading causes of death in tetraplegia.
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47 BMI
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49 Incidence of SAS
50 Kruskal-Wallis test
51 RDI
52 able-bodied people
53 age
54 analysis
55 apnea
56 apnea index
57 apnea syndrome
58 breathing
59 breathing data
60 cardiac medications
61 cardiovascular morbidity
62 cases
63 cause
64 cause of death
65 characteristics
66 circumference
67 complaints
68 context
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70 cord injury
71 correlation
72 data
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74 death
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76 differences
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78 gender
79 height
80 height of lesions
81 incidence
82 index
83 injury
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88 levels
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90 male patients
91 medications
92 men
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96 non-validated short questionnaire
97 normal BMI
98 number
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100 order
101 oxymetric values
102 pathogenesis
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104 patients
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106 previous studies
107 questionnaire
108 regard
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110 scale
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112 short questionnaire
113 significant correlation
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115 sleep
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118 spinal cord injury
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