Parathyroid hormone-related peptide: expression in prostate cancer bone metastases View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2002-03

AUTHORS

A A G Bryden, S Islam, A J Freemont, J H Shanks, N J R George, N W Clarke

ABSTRACT

Parathyroid hormone-related peptide (PTHrP) is a regulatory protein associated with cell growth in non-osseous tissues and with osteoclast stimulation in bone. It has been implicated in the pathogenesis of bone metastases, particularly in breast carcinoma. PTHrP is widely expressed in primary prostate cancers, but there are few reports of its expression in prostatic metastases. The aim of this study was to examine the expression of PTHrP in bone metastases from patients with untreated adenocarcinoma of the prostate. Ten bone biopsies containing metastatic deposits of untreated prostatic cancer were identified. These were immunohistochemically stained for PTHrP using a murine monoclonal antibody (PTHLP[Ab1]) and the streptavidin-biotin complex technique. Intensity of staining for PTHrP was graded by two observers. In total, PTHrP expression was positive in 5/10 specimens. This was graded as moderate in four and weak in one. In those specimens with positive staining, the expression varied between cells. There was no obvious association between expression of PTHrP and tumour differentiation. PTHrP is expressed in prostatic bone metastases and may have a role in their pathogenesis and pathophysiology. However, expression is not universal. More... »

PAGES

59

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.pcan.4500553

DOI

http://dx.doi.org/10.1038/sj.pcan.4500553

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035536253

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15195132


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenocarcinoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antibodies, Monoclonal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunoenzyme Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Parathyroid Hormone-Related Protein", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prostatic Neoplasms", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Christie and Hope Hospitals, Manchester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bryden", 
        "givenName": "A A G", 
        "id": "sg:person.01351502215.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351502215.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Manchester Royal Infirmary", 
          "id": "https://www.grid.ac/institutes/grid.419319.7", 
          "name": [
            "Manchester Royal Infirmary, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Islam", 
        "givenName": "S", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Manchester", 
          "id": "https://www.grid.ac/institutes/grid.5379.8", 
          "name": [
            "Osteoarticular Pathology, University of Manchester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Freemont", 
        "givenName": "A J", 
        "id": "sg:person.01242130226.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242130226.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Christie Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415720.5", 
          "name": [
            "Christie Hospital, Manchester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shanks", 
        "givenName": "J H", 
        "id": "sg:person.01274011557.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274011557.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Manchester University NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.498924.a", 
          "name": [
            "University Hospital of South Manchester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "George", 
        "givenName": "N J R", 
        "id": "sg:person.0722026325.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722026325.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Christie and Hope Hospitals, Manchester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Clarke", 
        "givenName": "N W", 
        "id": "sg:person.0653011450.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653011450.69"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/(sici)1097-0045(199607)29:1<20::aid-pros3>3.0.co;2-m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001060766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1054/bjoc.2001.1804", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003601096", 
          "https://doi.org/10.1054/bjoc.2001.1804"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1464-410x.1992.tb15461.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005108309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci118947", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011115012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0046-8177(96)90344-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013845627"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0959-8049(05)80127-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017274513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1097-0142(19971015)80:8+<1572::aid-cncr7>3.0.co;2-m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017809774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-9896(200006)191:2<170::aid-path620>3.0.co;2-h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036844895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0090-4295(94)90183-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041045575"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0090-4295(83)90147-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044481608"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.303.6816.1506", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045791318"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1464-410x.1991.tb15260.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046555793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00041552-199607000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048067918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00041552-199607000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048067918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.89.7.2732", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051878625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/endo.136.3.7867592", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064280034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074474822", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077035945", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078123958", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078552762", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079258167", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079597822", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-5347(17)54735-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082283563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000474311", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082780557"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082818622", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082937241", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2002-03", 
    "datePublishedReg": "2002-03-01", 
    "description": "Parathyroid hormone-related peptide (PTHrP) is a regulatory protein associated with cell growth in non-osseous tissues and with osteoclast stimulation in bone. It has been implicated in the pathogenesis of bone metastases, particularly in breast carcinoma. PTHrP is widely expressed in primary prostate cancers, but there are few reports of its expression in prostatic metastases. The aim of this study was to examine the expression of PTHrP in bone metastases from patients with untreated adenocarcinoma of the prostate. Ten bone biopsies containing metastatic deposits of untreated prostatic cancer were identified. These were immunohistochemically stained for PTHrP using a murine monoclonal antibody (PTHLP[Ab1]) and the streptavidin-biotin complex technique. Intensity of staining for PTHrP was graded by two observers. In total, PTHrP expression was positive in 5/10 specimens. This was graded as moderate in four and weak in one. In those specimens with positive staining, the expression varied between cells. There was no obvious association between expression of PTHrP and tumour differentiation. PTHrP is expressed in prostatic bone metastases and may have a role in their pathogenesis and pathophysiology. However, expression is not universal.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/sj.pcan.4500553", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1119336", 
        "issn": [
          "1365-7852", 
          "1476-5608"
        ], 
        "name": "Prostate Cancer and Prostatic Diseases", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "5"
      }
    ], 
    "name": "Parathyroid hormone-related peptide: expression in prostate cancer bone metastases", 
    "pagination": "59", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "a94779fafeacb116bcedf416569b375e0b3d26b717171114529c4f607871d402"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15195132"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9815755"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.pcan.4500553"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1035536253"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.pcan.4500553", 
      "https://app.dimensions.ai/details/publication/pub.1035536253"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:06", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000360_0000000360/records_118335_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/4500553"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.pcan.4500553'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.pcan.4500553'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.pcan.4500553'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.pcan.4500553'


 

This table displays all metadata directly associated to this object as RDF triples.

224 TRIPLES      21 PREDICATES      64 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.pcan.4500553 schema:about N38ccfda0545e49fbb0ad629042e98424
2 N3faa4421b1234c3d956508a1a930d0bc
3 N781ab0ceae0147cd816c2a6e372ebb41
4 N89ae58f7e9b940f2bdbd180c13238efc
5 N89b73614ad404a53905ac215e618e58f
6 Na9cb56b157674e9faadfa4a2785c146e
7 Naa67b880181241fdaecbef824a21fb7d
8 Naaf7351bdd774b0c8710fd13aba43a5d
9 Ne3477db2d9984265bf5e0c295c683d69
10 Nf51a92af732041fa99d4be29edad1d00
11 anzsrc-for:11
12 anzsrc-for:1103
13 schema:author Na35ec4c10c044e2eb8609aa3bff5b9b2
14 schema:citation sg:pub.10.1054/bjoc.2001.1804
15 https://app.dimensions.ai/details/publication/pub.1074474822
16 https://app.dimensions.ai/details/publication/pub.1077035945
17 https://app.dimensions.ai/details/publication/pub.1078123958
18 https://app.dimensions.ai/details/publication/pub.1078552762
19 https://app.dimensions.ai/details/publication/pub.1079258167
20 https://app.dimensions.ai/details/publication/pub.1079597822
21 https://app.dimensions.ai/details/publication/pub.1082818622
22 https://app.dimensions.ai/details/publication/pub.1082937241
23 https://doi.org/10.1002/(sici)1096-9896(200006)191:2<170::aid-path620>3.0.co;2-h
24 https://doi.org/10.1002/(sici)1097-0045(199607)29:1<20::aid-pros3>3.0.co;2-m
25 https://doi.org/10.1002/(sici)1097-0142(19971015)80:8+<1572::aid-cncr7>3.0.co;2-m
26 https://doi.org/10.1016/0090-4295(83)90147-4
27 https://doi.org/10.1016/0090-4295(94)90183-x
28 https://doi.org/10.1016/s0022-5347(17)54735-7
29 https://doi.org/10.1016/s0046-8177(96)90344-5
30 https://doi.org/10.1016/s0959-8049(05)80127-3
31 https://doi.org/10.1073/pnas.89.7.2732
32 https://doi.org/10.1097/00041552-199607000-00004
33 https://doi.org/10.1111/j.1464-410x.1991.tb15260.x
34 https://doi.org/10.1111/j.1464-410x.1992.tb15461.x
35 https://doi.org/10.1136/bmj.303.6816.1506
36 https://doi.org/10.1159/000474311
37 https://doi.org/10.1172/jci118947
38 https://doi.org/10.1210/endo.136.3.7867592
39 schema:datePublished 2002-03
40 schema:datePublishedReg 2002-03-01
41 schema:description Parathyroid hormone-related peptide (PTHrP) is a regulatory protein associated with cell growth in non-osseous tissues and with osteoclast stimulation in bone. It has been implicated in the pathogenesis of bone metastases, particularly in breast carcinoma. PTHrP is widely expressed in primary prostate cancers, but there are few reports of its expression in prostatic metastases. The aim of this study was to examine the expression of PTHrP in bone metastases from patients with untreated adenocarcinoma of the prostate. Ten bone biopsies containing metastatic deposits of untreated prostatic cancer were identified. These were immunohistochemically stained for PTHrP using a murine monoclonal antibody (PTHLP[Ab1]) and the streptavidin-biotin complex technique. Intensity of staining for PTHrP was graded by two observers. In total, PTHrP expression was positive in 5/10 specimens. This was graded as moderate in four and weak in one. In those specimens with positive staining, the expression varied between cells. There was no obvious association between expression of PTHrP and tumour differentiation. PTHrP is expressed in prostatic bone metastases and may have a role in their pathogenesis and pathophysiology. However, expression is not universal.
42 schema:genre research_article
43 schema:inLanguage en
44 schema:isAccessibleForFree true
45 schema:isPartOf N43fad55a41bc40e5a2e52e4bf75a34e2
46 Na10a55258fcd4376bd6eb5b431ec2871
47 sg:journal.1119336
48 schema:name Parathyroid hormone-related peptide: expression in prostate cancer bone metastases
49 schema:pagination 59
50 schema:productId N06b2e502aa6a4a04bf8dd7f39868034b
51 N25da05a2d66e4741b7174eaa9fa0e7b4
52 N3626e336e8af46f1aa494ac5d2bcab5b
53 N364412ae4c9b424ab8365ea05b399ac1
54 N5736ba89859f4857ad7a3f256ba877cf
55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035536253
56 https://doi.org/10.1038/sj.pcan.4500553
57 schema:sdDatePublished 2019-04-11T12:06
58 schema:sdLicense https://scigraph.springernature.com/explorer/license/
59 schema:sdPublisher N35acc29756ea4e3381596df2349424df
60 schema:url https://www.nature.com/articles/4500553
61 sgo:license sg:explorer/license/
62 sgo:sdDataset articles
63 rdf:type schema:ScholarlyArticle
64 N06b2e502aa6a4a04bf8dd7f39868034b schema:name readcube_id
65 schema:value a94779fafeacb116bcedf416569b375e0b3d26b717171114529c4f607871d402
66 rdf:type schema:PropertyValue
67 N15ee82b3759240b7bf6c0a49328e2d9b rdf:first sg:person.0722026325.28
68 rdf:rest Nde4aa34cae034b21b76b7afbd78ed07c
69 N25da05a2d66e4741b7174eaa9fa0e7b4 schema:name doi
70 schema:value 10.1038/sj.pcan.4500553
71 rdf:type schema:PropertyValue
72 N35acc29756ea4e3381596df2349424df schema:name Springer Nature - SN SciGraph project
73 rdf:type schema:Organization
74 N3626e336e8af46f1aa494ac5d2bcab5b schema:name dimensions_id
75 schema:value pub.1035536253
76 rdf:type schema:PropertyValue
77 N364412ae4c9b424ab8365ea05b399ac1 schema:name nlm_unique_id
78 schema:value 9815755
79 rdf:type schema:PropertyValue
80 N38ccfda0545e49fbb0ad629042e98424 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Humans
82 rdf:type schema:DefinedTerm
83 N3faa4421b1234c3d956508a1a930d0bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Antibodies, Monoclonal
85 rdf:type schema:DefinedTerm
86 N43fad55a41bc40e5a2e52e4bf75a34e2 schema:issueNumber 1
87 rdf:type schema:PublicationIssue
88 N528a60481ebb4cb3a6547ae27cd0c9b9 rdf:first sg:person.01274011557.52
89 rdf:rest N15ee82b3759240b7bf6c0a49328e2d9b
90 N5736ba89859f4857ad7a3f256ba877cf schema:name pubmed_id
91 schema:value 15195132
92 rdf:type schema:PropertyValue
93 N623c7c08e2f54f16b3b0c8c4af1dbeae schema:name Christie and Hope Hospitals, Manchester, UK
94 rdf:type schema:Organization
95 N781ab0ceae0147cd816c2a6e372ebb41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Immunoenzyme Techniques
97 rdf:type schema:DefinedTerm
98 N89ae58f7e9b940f2bdbd180c13238efc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Prostatic Neoplasms
100 rdf:type schema:DefinedTerm
101 N89b73614ad404a53905ac215e618e58f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Adenocarcinoma
103 rdf:type schema:DefinedTerm
104 N89b8b4912f3d495cb4c663d00b1c6f0f schema:name Christie and Hope Hospitals, Manchester, UK
105 rdf:type schema:Organization
106 N91f2daa6f5e44aaaad408c2b3196aa3b schema:affiliation https://www.grid.ac/institutes/grid.419319.7
107 schema:familyName Islam
108 schema:givenName S
109 rdf:type schema:Person
110 Na10a55258fcd4376bd6eb5b431ec2871 schema:volumeNumber 5
111 rdf:type schema:PublicationVolume
112 Na35ec4c10c044e2eb8609aa3bff5b9b2 rdf:first sg:person.01351502215.99
113 rdf:rest Nc5b2f927ee23437685f1af023fd5502f
114 Na9cb56b157674e9faadfa4a2785c146e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Biomarkers, Tumor
116 rdf:type schema:DefinedTerm
117 Naa67b880181241fdaecbef824a21fb7d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Male
119 rdf:type schema:DefinedTerm
120 Naaf7351bdd774b0c8710fd13aba43a5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Parathyroid Hormone-Related Protein
122 rdf:type schema:DefinedTerm
123 Nc5b2f927ee23437685f1af023fd5502f rdf:first N91f2daa6f5e44aaaad408c2b3196aa3b
124 rdf:rest Ne37691deabfa4426bc04bbb47720c649
125 Nde4aa34cae034b21b76b7afbd78ed07c rdf:first sg:person.0653011450.69
126 rdf:rest rdf:nil
127 Ne3477db2d9984265bf5e0c295c683d69 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Neoplasm Proteins
129 rdf:type schema:DefinedTerm
130 Ne37691deabfa4426bc04bbb47720c649 rdf:first sg:person.01242130226.89
131 rdf:rest N528a60481ebb4cb3a6547ae27cd0c9b9
132 Nf51a92af732041fa99d4be29edad1d00 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Bone Neoplasms
134 rdf:type schema:DefinedTerm
135 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
136 schema:name Medical and Health Sciences
137 rdf:type schema:DefinedTerm
138 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
139 schema:name Clinical Sciences
140 rdf:type schema:DefinedTerm
141 sg:journal.1119336 schema:issn 1365-7852
142 1476-5608
143 schema:name Prostate Cancer and Prostatic Diseases
144 rdf:type schema:Periodical
145 sg:person.01242130226.89 schema:affiliation https://www.grid.ac/institutes/grid.5379.8
146 schema:familyName Freemont
147 schema:givenName A J
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242130226.89
149 rdf:type schema:Person
150 sg:person.01274011557.52 schema:affiliation https://www.grid.ac/institutes/grid.415720.5
151 schema:familyName Shanks
152 schema:givenName J H
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274011557.52
154 rdf:type schema:Person
155 sg:person.01351502215.99 schema:affiliation N623c7c08e2f54f16b3b0c8c4af1dbeae
156 schema:familyName Bryden
157 schema:givenName A A G
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351502215.99
159 rdf:type schema:Person
160 sg:person.0653011450.69 schema:affiliation N89b8b4912f3d495cb4c663d00b1c6f0f
161 schema:familyName Clarke
162 schema:givenName N W
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653011450.69
164 rdf:type schema:Person
165 sg:person.0722026325.28 schema:affiliation https://www.grid.ac/institutes/grid.498924.a
166 schema:familyName George
167 schema:givenName N J R
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722026325.28
169 rdf:type schema:Person
170 sg:pub.10.1054/bjoc.2001.1804 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003601096
171 https://doi.org/10.1054/bjoc.2001.1804
172 rdf:type schema:CreativeWork
173 https://app.dimensions.ai/details/publication/pub.1074474822 schema:CreativeWork
174 https://app.dimensions.ai/details/publication/pub.1077035945 schema:CreativeWork
175 https://app.dimensions.ai/details/publication/pub.1078123958 schema:CreativeWork
176 https://app.dimensions.ai/details/publication/pub.1078552762 schema:CreativeWork
177 https://app.dimensions.ai/details/publication/pub.1079258167 schema:CreativeWork
178 https://app.dimensions.ai/details/publication/pub.1079597822 schema:CreativeWork
179 https://app.dimensions.ai/details/publication/pub.1082818622 schema:CreativeWork
180 https://app.dimensions.ai/details/publication/pub.1082937241 schema:CreativeWork
181 https://doi.org/10.1002/(sici)1096-9896(200006)191:2<170::aid-path620>3.0.co;2-h schema:sameAs https://app.dimensions.ai/details/publication/pub.1036844895
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1002/(sici)1097-0045(199607)29:1<20::aid-pros3>3.0.co;2-m schema:sameAs https://app.dimensions.ai/details/publication/pub.1001060766
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1002/(sici)1097-0142(19971015)80:8+<1572::aid-cncr7>3.0.co;2-m schema:sameAs https://app.dimensions.ai/details/publication/pub.1017809774
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1016/0090-4295(83)90147-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044481608
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1016/0090-4295(94)90183-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1041045575
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1016/s0022-5347(17)54735-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082283563
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1016/s0046-8177(96)90344-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013845627
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1016/s0959-8049(05)80127-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017274513
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1073/pnas.89.7.2732 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051878625
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1097/00041552-199607000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048067918
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1111/j.1464-410x.1991.tb15260.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1046555793
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1111/j.1464-410x.1992.tb15461.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005108309
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1136/bmj.303.6816.1506 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045791318
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1159/000474311 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082780557
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1172/jci118947 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011115012
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1210/endo.136.3.7867592 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064280034
212 rdf:type schema:CreativeWork
213 https://www.grid.ac/institutes/grid.415720.5 schema:alternateName The Christie Hospital
214 schema:name Christie Hospital, Manchester, UK
215 rdf:type schema:Organization
216 https://www.grid.ac/institutes/grid.419319.7 schema:alternateName Manchester Royal Infirmary
217 schema:name Manchester Royal Infirmary, UK
218 rdf:type schema:Organization
219 https://www.grid.ac/institutes/grid.498924.a schema:alternateName Manchester University NHS Foundation Trust
220 schema:name University Hospital of South Manchester, UK
221 rdf:type schema:Organization
222 https://www.grid.ac/institutes/grid.5379.8 schema:alternateName University of Manchester
223 schema:name Osteoarticular Pathology, University of Manchester, UK
224 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...