Introduction to NF-κB: players, pathways, perspectives View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-10

AUTHORS

T D Gilmore

ABSTRACT

This article serves as an introduction to the collection of reviews on nuclear factor-kappaB (NF-kappaB). It provides an overview of the discovery and current status of NF-kappaB as a research topic. Described are the structures, activities and regulation of the proteins in the NF-kappaB family of transcription factors. NF-kappaB signaling is primarily regulated by inhibitor kappaB (IkappaB) proteins and the IkappaB kinase complex through two major pathways: the canonical and non-canonical NF-kappaB pathways. The organization and focus of articles included in the following reviews are described, as well as likely future areas of research interest on NF-kappaB. More... »

PAGES

1209954

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.onc.1209954

DOI

http://dx.doi.org/10.1038/sj.onc.1209954

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026298568

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17072321


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