Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the Aβ ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2001-04

AUTHORS

Ralf Ruediger, Huong T Pham, Gernot Walter

ABSTRACT

Protein phosphatase 2A (PP2A) consists of three subunits, A, B and C. The A and B subunits have regulatory functions while C is the catalytic subunit. PP2A core enzyme is composed of subunits A and C, and the holoenzyme of subunits A, B and C. All subunits exist as multiple isoforms or splice variants. The A subunit exists as two isoforms, A alpha and A beta. Here we report about the properties of eight A beta mutants, which were found in human lung and colon cancer. These mutants were reconstructed by site-directed mutagenesis and assayed for their ability to bind B and C subunits. Two mutants showed decreased binding of PR72, a member of the B" family of B subunits, but normal C subunit binding; two mutants exhibited decreased binding of the C subunit and of B"/PR72; and one mutant showed increased binding of both the C subunit and B"/PR72. Of three mutants that behaved like the wild-type A beta subunit, one is a polymorphic variant and another one is altered outside the binding region for B and C subunits. Importantly, we also found that the wild-type A alpha and A beta isoforms, although 85% identical, are remarkably different in their ability to bind B and C subunits. Our findings may have important implications in regard to the role of PP2A as a tumor suppressor. More... »

PAGES

1892

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.onc.1204279

DOI

http://dx.doi.org/10.1038/sj.onc.1204279

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036237077

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11313937


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colonic Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Isoenzymes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lung Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phosphoprotein Phosphatases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Phosphatase 2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Subunits", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of California, San Diego", 
          "id": "https://www.grid.ac/institutes/grid.266100.3", 
          "name": [
            "Department of Pathology, University of California at San Diego, La Jolla, California, CA 92093, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ruediger", 
        "givenName": "Ralf", 
        "id": "sg:person.0741517035.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741517035.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, San Diego", 
          "id": "https://www.grid.ac/institutes/grid.266100.3", 
          "name": [
            "Department of Pathology, University of California at San Diego, La Jolla, California, CA 92093, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pham", 
        "givenName": "Huong T", 
        "id": "sg:person.01157646153.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157646153.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, San Diego", 
          "id": "https://www.grid.ac/institutes/grid.266100.3", 
          "name": [
            "Department of Pathology, University of California at San Diego, La Jolla, California, CA 92093, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Walter", 
        "givenName": "Gernot", 
        "id": "sg:person.013350022702.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013350022702.51"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1995.1037g.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000241277"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-5793(99)01377-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002097167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0955-0674(99)00074-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002618028"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.11.11.5767", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003205340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.95.21.12370", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003525595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1203389", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004683221", 
          "https://doi.org/10.1038/sj.onc.1203389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1203389", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004683221", 
          "https://doi.org/10.1038/sj.onc.1203389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.11.8.4282", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005589758"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.20.3.1021-1029.2000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006647685"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/385454a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008345653", 
          "https://doi.org/10.1038/385454a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2560283", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010638649"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2560283", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010638649"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.74.17.7869-7877.2000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010687037"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1203070", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011251249", 
          "https://doi.org/10.1038/sj.onc.1203070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1203070", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011251249", 
          "https://doi.org/10.1038/sj.onc.1203070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.273.21.13119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011310347"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/viro.1997.8873", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012704927"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.17.3.1692", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014834661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.36.22081", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015039029"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.85.6.1768", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015147607"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1202316", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017077389", 
          "https://doi.org/10.1038/sj.onc.1202316"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1202316", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017077389", 
          "https://doi.org/10.1038/sj.onc.1202316"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.12.11.4872", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017244907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.86.22.8669", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019845198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(87)80966-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024571366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.96.18.10080", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024944313"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.273.51.34157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028680963"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.19.11059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029641545"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(88)90032-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030331431"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(88)90032-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030331431"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1203705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033693201", 
          "https://doi.org/10.1038/sj.onc.1203705"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1203705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033693201", 
          "https://doi.org/10.1038/sj.onc.1203705"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.274.6.3439", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034189941"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.9.5164", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034385159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.274.2.687", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035213793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m003259200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037070609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.14.7.4616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037403441"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.84.14.4880", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037417773"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.2000.2733", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041733311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1204059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042334898", 
          "https://doi.org/10.1038/sj.onc.1204059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1204059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042334898", 
          "https://doi.org/10.1038/sj.onc.1204059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-419x(93)90005-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044945518"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-419x(93)90005-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044945518"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.270.44.26123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045295025"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-2952(98)00245-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045456533"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)80963-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046345009"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.5.2578", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047335549"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.47.2.268", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048986495"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.280.5367.1258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049216469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1201591", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052455841", 
          "https://doi.org/10.1038/sj.onc.1201591"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1201591", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052455841", 
          "https://doi.org/10.1038/sj.onc.1201591"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1006888228156", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052759575", 
          "https://doi.org/10.1023/a:1006888228156"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(95)01500-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052870206"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00205a023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055165181"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00229a001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055166181"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00397a003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055173764"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00465a002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055177292"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a021726", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059960528"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.276.5314.952", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062556652"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.282.5387.284", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062562774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.283.5410.2089", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062564650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.2000.279.3.h1307", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074699931"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075606545", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075949631", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079002108", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079027926", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082627475", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082712417", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082723822", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082787551", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/physrev.1993.73.4.673", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082797762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1996.tb01107.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083035103"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083359444", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2001-04", 
    "datePublishedReg": "2001-04-01", 
    "description": "Protein phosphatase 2A (PP2A) consists of three subunits, A, B and C. The A and B subunits have regulatory functions while C is the catalytic subunit. PP2A core enzyme is composed of subunits A and C, and the holoenzyme of subunits A, B and C. All subunits exist as multiple isoforms or splice variants. The A subunit exists as two isoforms, A alpha and A beta. Here we report about the properties of eight A beta mutants, which were found in human lung and colon cancer. These mutants were reconstructed by site-directed mutagenesis and assayed for their ability to bind B and C subunits. Two mutants showed decreased binding of PR72, a member of the B\" family of B subunits, but normal C subunit binding; two mutants exhibited decreased binding of the C subunit and of B\"/PR72; and one mutant showed increased binding of both the C subunit and B\"/PR72. Of three mutants that behaved like the wild-type A beta subunit, one is a polymorphic variant and another one is altered outside the binding region for B and C subunits. Importantly, we also found that the wild-type A alpha and A beta isoforms, although 85% identical, are remarkably different in their ability to bind B and C subunits. Our findings may have important implications in regard to the role of PP2A as a tumor suppressor.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/sj.onc.1204279", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2467650", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1097543", 
        "issn": [
          "0950-9232", 
          "1476-5594"
        ], 
        "name": "Oncogene", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "15", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "20"
      }
    ], 
    "name": "Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A\u03b2 subunit gene", 
    "pagination": "1892", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "ac9e24a0803377c2340d9d2cbe3123c3417db24f3f0b888608e78a0f42b7951d"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "11313937"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8711562"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.onc.1204279"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036237077"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.onc.1204279", 
      "https://app.dimensions.ai/details/publication/pub.1036237077"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:14", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000361_0000000361/records_54003_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/1204279"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.onc.1204279'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.onc.1204279'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.onc.1204279'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.onc.1204279'


 

This table displays all metadata directly associated to this object as RDF triples.

316 TRIPLES      21 PREDICATES      103 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.onc.1204279 schema:about N0fd2448bad364ffb91fe9935dcc40f18
2 N54f0e72167424ff5bb20d5c9e70c3086
3 N5732aad13af9409a96081bbf37be4be7
4 N62bb1f9bd5984d1b8e43a577856f28d5
5 N8990ec3beeee410397a597e505c23f99
6 Na3bc36070a044d30bb251e57c819bf7c
7 Nc658656c5aa4459a9a7198fd98516d00
8 Ncbf07757623f4f0e82d89fbfb01fd667
9 Nceeff7ab303f46d7aac00d6e778b2d7e
10 Ndf8d22e2377843c8a834f3883b08260f
11 anzsrc-for:06
12 anzsrc-for:0601
13 schema:author N3b73ea0f8bb842ebbbd61eb2fda7e11c
14 schema:citation sg:pub.10.1023/a:1006888228156
15 sg:pub.10.1038/385454a0
16 sg:pub.10.1038/sj.onc.1201591
17 sg:pub.10.1038/sj.onc.1202316
18 sg:pub.10.1038/sj.onc.1203070
19 sg:pub.10.1038/sj.onc.1203389
20 sg:pub.10.1038/sj.onc.1203705
21 sg:pub.10.1038/sj.onc.1204059
22 https://app.dimensions.ai/details/publication/pub.1075606545
23 https://app.dimensions.ai/details/publication/pub.1075949631
24 https://app.dimensions.ai/details/publication/pub.1079002108
25 https://app.dimensions.ai/details/publication/pub.1079027926
26 https://app.dimensions.ai/details/publication/pub.1082627475
27 https://app.dimensions.ai/details/publication/pub.1082712417
28 https://app.dimensions.ai/details/publication/pub.1082723822
29 https://app.dimensions.ai/details/publication/pub.1082787551
30 https://app.dimensions.ai/details/publication/pub.1083359444
31 https://doi.org/10.1002/j.1460-2075.1996.tb01107.x
32 https://doi.org/10.1006/bbrc.2000.2733
33 https://doi.org/10.1006/viro.1997.8873
34 https://doi.org/10.1016/0014-5793(87)80966-3
35 https://doi.org/10.1016/0014-5793(95)01500-0
36 https://doi.org/10.1016/0167-4781(88)90032-2
37 https://doi.org/10.1016/0304-419x(93)90005-w
38 https://doi.org/10.1016/s0006-2952(98)00245-7
39 https://doi.org/10.1016/s0014-5793(99)01377-0
40 https://doi.org/10.1016/s0092-8674(00)80963-0
41 https://doi.org/10.1016/s0955-0674(99)00074-5
42 https://doi.org/10.1021/bi00205a023
43 https://doi.org/10.1021/bi00229a001
44 https://doi.org/10.1021/bi00397a003
45 https://doi.org/10.1021/bi00465a002
46 https://doi.org/10.1042/bj2560283
47 https://doi.org/10.1073/pnas.84.14.4880
48 https://doi.org/10.1073/pnas.85.6.1768
49 https://doi.org/10.1073/pnas.86.22.8669
50 https://doi.org/10.1073/pnas.95.21.12370
51 https://doi.org/10.1073/pnas.96.18.10080
52 https://doi.org/10.1074/jbc.270.44.26123
53 https://doi.org/10.1074/jbc.271.19.11059
54 https://doi.org/10.1074/jbc.271.36.22081
55 https://doi.org/10.1074/jbc.271.5.2578
56 https://doi.org/10.1074/jbc.271.9.5164
57 https://doi.org/10.1074/jbc.273.21.13119
58 https://doi.org/10.1074/jbc.273.51.34157
59 https://doi.org/10.1074/jbc.274.2.687
60 https://doi.org/10.1074/jbc.274.6.3439
61 https://doi.org/10.1074/jbc.m003259200
62 https://doi.org/10.1093/oxfordjournals.jbchem.a021726
63 https://doi.org/10.1111/j.1432-1033.1995.1037g.x
64 https://doi.org/10.1126/science.276.5314.952
65 https://doi.org/10.1126/science.280.5367.1258
66 https://doi.org/10.1126/science.282.5387.284
67 https://doi.org/10.1126/science.283.5410.2089
68 https://doi.org/10.1128/jvi.74.17.7869-7877.2000
69 https://doi.org/10.1128/mcb.11.11.5767
70 https://doi.org/10.1128/mcb.11.8.4282
71 https://doi.org/10.1128/mcb.12.11.4872
72 https://doi.org/10.1128/mcb.14.7.4616
73 https://doi.org/10.1128/mcb.17.3.1692
74 https://doi.org/10.1128/mcb.20.3.1021-1029.2000
75 https://doi.org/10.1136/gut.47.2.268
76 https://doi.org/10.1152/ajpheart.2000.279.3.h1307
77 https://doi.org/10.1152/physrev.1993.73.4.673
78 schema:datePublished 2001-04
79 schema:datePublishedReg 2001-04-01
80 schema:description Protein phosphatase 2A (PP2A) consists of three subunits, A, B and C. The A and B subunits have regulatory functions while C is the catalytic subunit. PP2A core enzyme is composed of subunits A and C, and the holoenzyme of subunits A, B and C. All subunits exist as multiple isoforms or splice variants. The A subunit exists as two isoforms, A alpha and A beta. Here we report about the properties of eight A beta mutants, which were found in human lung and colon cancer. These mutants were reconstructed by site-directed mutagenesis and assayed for their ability to bind B and C subunits. Two mutants showed decreased binding of PR72, a member of the B" family of B subunits, but normal C subunit binding; two mutants exhibited decreased binding of the C subunit and of B"/PR72; and one mutant showed increased binding of both the C subunit and B"/PR72. Of three mutants that behaved like the wild-type A beta subunit, one is a polymorphic variant and another one is altered outside the binding region for B and C subunits. Importantly, we also found that the wild-type A alpha and A beta isoforms, although 85% identical, are remarkably different in their ability to bind B and C subunits. Our findings may have important implications in regard to the role of PP2A as a tumor suppressor.
81 schema:genre research_article
82 schema:inLanguage en
83 schema:isAccessibleForFree true
84 schema:isPartOf N28f5916b6b5747e7af0b40ea340768bc
85 Nf74adb85f978468b9d01f1fd57380cea
86 sg:journal.1097543
87 schema:name Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the Aβ subunit gene
88 schema:pagination 1892
89 schema:productId N18ac2b4b7109431cbe3fb2957a5cb561
90 N7f09d9da42554fd3a917bd582ee85ad4
91 N858bd77e57cc40e0b8cb6fe077ef0183
92 N926c65f4524546c49d372ec6897ffc09
93 Nfe084e25a1cb41428633606ca3c7bbe0
94 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036237077
95 https://doi.org/10.1038/sj.onc.1204279
96 schema:sdDatePublished 2019-04-11T12:14
97 schema:sdLicense https://scigraph.springernature.com/explorer/license/
98 schema:sdPublisher Ncecfc776e5674261a8ac4a0b91f91d20
99 schema:url https://www.nature.com/articles/1204279
100 sgo:license sg:explorer/license/
101 sgo:sdDataset articles
102 rdf:type schema:ScholarlyArticle
103 N0ee8a388c3784d44b2be1de6e1e04686 rdf:first sg:person.013350022702.51
104 rdf:rest rdf:nil
105 N0fd2448bad364ffb91fe9935dcc40f18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Phosphoprotein Phosphatases
107 rdf:type schema:DefinedTerm
108 N18ac2b4b7109431cbe3fb2957a5cb561 schema:name dimensions_id
109 schema:value pub.1036237077
110 rdf:type schema:PropertyValue
111 N28f5916b6b5747e7af0b40ea340768bc schema:issueNumber 15
112 rdf:type schema:PublicationIssue
113 N3b73ea0f8bb842ebbbd61eb2fda7e11c rdf:first sg:person.0741517035.11
114 rdf:rest Nf91269ac04af4e0c80d0a4fd1ee6b7dc
115 N54f0e72167424ff5bb20d5c9e70c3086 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Molecular Sequence Data
117 rdf:type schema:DefinedTerm
118 N5732aad13af9409a96081bbf37be4be7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Colonic Neoplasms
120 rdf:type schema:DefinedTerm
121 N62bb1f9bd5984d1b8e43a577856f28d5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Humans
123 rdf:type schema:DefinedTerm
124 N7f09d9da42554fd3a917bd582ee85ad4 schema:name pubmed_id
125 schema:value 11313937
126 rdf:type schema:PropertyValue
127 N858bd77e57cc40e0b8cb6fe077ef0183 schema:name readcube_id
128 schema:value ac9e24a0803377c2340d9d2cbe3123c3417db24f3f0b888608e78a0f42b7951d
129 rdf:type schema:PropertyValue
130 N8990ec3beeee410397a597e505c23f99 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Protein Subunits
132 rdf:type schema:DefinedTerm
133 N926c65f4524546c49d372ec6897ffc09 schema:name doi
134 schema:value 10.1038/sj.onc.1204279
135 rdf:type schema:PropertyValue
136 Na3bc36070a044d30bb251e57c819bf7c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Amino Acid Sequence
138 rdf:type schema:DefinedTerm
139 Nc658656c5aa4459a9a7198fd98516d00 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Mutation
141 rdf:type schema:DefinedTerm
142 Ncbf07757623f4f0e82d89fbfb01fd667 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Lung Neoplasms
144 rdf:type schema:DefinedTerm
145 Ncecfc776e5674261a8ac4a0b91f91d20 schema:name Springer Nature - SN SciGraph project
146 rdf:type schema:Organization
147 Nceeff7ab303f46d7aac00d6e778b2d7e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Isoenzymes
149 rdf:type schema:DefinedTerm
150 Ndf8d22e2377843c8a834f3883b08260f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Protein Phosphatase 2
152 rdf:type schema:DefinedTerm
153 Nf74adb85f978468b9d01f1fd57380cea schema:volumeNumber 20
154 rdf:type schema:PublicationVolume
155 Nf91269ac04af4e0c80d0a4fd1ee6b7dc rdf:first sg:person.01157646153.61
156 rdf:rest N0ee8a388c3784d44b2be1de6e1e04686
157 Nfe084e25a1cb41428633606ca3c7bbe0 schema:name nlm_unique_id
158 schema:value 8711562
159 rdf:type schema:PropertyValue
160 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
161 schema:name Biological Sciences
162 rdf:type schema:DefinedTerm
163 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
164 schema:name Biochemistry and Cell Biology
165 rdf:type schema:DefinedTerm
166 sg:grant.2467650 http://pending.schema.org/fundedItem sg:pub.10.1038/sj.onc.1204279
167 rdf:type schema:MonetaryGrant
168 sg:journal.1097543 schema:issn 0950-9232
169 1476-5594
170 schema:name Oncogene
171 rdf:type schema:Periodical
172 sg:person.01157646153.61 schema:affiliation https://www.grid.ac/institutes/grid.266100.3
173 schema:familyName Pham
174 schema:givenName Huong T
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157646153.61
176 rdf:type schema:Person
177 sg:person.013350022702.51 schema:affiliation https://www.grid.ac/institutes/grid.266100.3
178 schema:familyName Walter
179 schema:givenName Gernot
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013350022702.51
181 rdf:type schema:Person
182 sg:person.0741517035.11 schema:affiliation https://www.grid.ac/institutes/grid.266100.3
183 schema:familyName Ruediger
184 schema:givenName Ralf
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741517035.11
186 rdf:type schema:Person
187 sg:pub.10.1023/a:1006888228156 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052759575
188 https://doi.org/10.1023/a:1006888228156
189 rdf:type schema:CreativeWork
190 sg:pub.10.1038/385454a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008345653
191 https://doi.org/10.1038/385454a0
192 rdf:type schema:CreativeWork
193 sg:pub.10.1038/sj.onc.1201591 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052455841
194 https://doi.org/10.1038/sj.onc.1201591
195 rdf:type schema:CreativeWork
196 sg:pub.10.1038/sj.onc.1202316 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017077389
197 https://doi.org/10.1038/sj.onc.1202316
198 rdf:type schema:CreativeWork
199 sg:pub.10.1038/sj.onc.1203070 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011251249
200 https://doi.org/10.1038/sj.onc.1203070
201 rdf:type schema:CreativeWork
202 sg:pub.10.1038/sj.onc.1203389 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004683221
203 https://doi.org/10.1038/sj.onc.1203389
204 rdf:type schema:CreativeWork
205 sg:pub.10.1038/sj.onc.1203705 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033693201
206 https://doi.org/10.1038/sj.onc.1203705
207 rdf:type schema:CreativeWork
208 sg:pub.10.1038/sj.onc.1204059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042334898
209 https://doi.org/10.1038/sj.onc.1204059
210 rdf:type schema:CreativeWork
211 https://app.dimensions.ai/details/publication/pub.1075606545 schema:CreativeWork
212 https://app.dimensions.ai/details/publication/pub.1075949631 schema:CreativeWork
213 https://app.dimensions.ai/details/publication/pub.1079002108 schema:CreativeWork
214 https://app.dimensions.ai/details/publication/pub.1079027926 schema:CreativeWork
215 https://app.dimensions.ai/details/publication/pub.1082627475 schema:CreativeWork
216 https://app.dimensions.ai/details/publication/pub.1082712417 schema:CreativeWork
217 https://app.dimensions.ai/details/publication/pub.1082723822 schema:CreativeWork
218 https://app.dimensions.ai/details/publication/pub.1082787551 schema:CreativeWork
219 https://app.dimensions.ai/details/publication/pub.1083359444 schema:CreativeWork
220 https://doi.org/10.1002/j.1460-2075.1996.tb01107.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1083035103
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1006/bbrc.2000.2733 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041733311
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1006/viro.1997.8873 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012704927
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1016/0014-5793(87)80966-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024571366
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1016/0014-5793(95)01500-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052870206
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1016/0167-4781(88)90032-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030331431
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1016/0304-419x(93)90005-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1044945518
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1016/s0006-2952(98)00245-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045456533
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/s0014-5793(99)01377-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002097167
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/s0092-8674(00)80963-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046345009
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/s0955-0674(99)00074-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002618028
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1021/bi00205a023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055165181
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1021/bi00229a001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055166181
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1021/bi00397a003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055173764
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1021/bi00465a002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055177292
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1042/bj2560283 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010638649
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1073/pnas.84.14.4880 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037417773
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1073/pnas.85.6.1768 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015147607
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1073/pnas.86.22.8669 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019845198
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1073/pnas.95.21.12370 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003525595
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1073/pnas.96.18.10080 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024944313
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1074/jbc.270.44.26123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045295025
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1074/jbc.271.19.11059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029641545
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1074/jbc.271.36.22081 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015039029
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1074/jbc.271.5.2578 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047335549
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1074/jbc.271.9.5164 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034385159
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1074/jbc.273.21.13119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011310347
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1074/jbc.273.51.34157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028680963
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1074/jbc.274.2.687 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035213793
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1074/jbc.274.6.3439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034189941
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1074/jbc.m003259200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037070609
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1093/oxfordjournals.jbchem.a021726 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059960528
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1111/j.1432-1033.1995.1037g.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1000241277
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1126/science.276.5314.952 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062556652
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1126/science.280.5367.1258 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049216469
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1126/science.282.5387.284 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062562774
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1126/science.283.5410.2089 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062564650
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1128/jvi.74.17.7869-7877.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010687037
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1128/mcb.11.11.5767 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003205340
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1128/mcb.11.8.4282 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005589758
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1128/mcb.12.11.4872 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017244907
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1128/mcb.14.7.4616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037403441
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1128/mcb.17.3.1692 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014834661
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1128/mcb.20.3.1021-1029.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006647685
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1136/gut.47.2.268 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048986495
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1152/ajpheart.2000.279.3.h1307 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074699931
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1152/physrev.1993.73.4.673 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082797762
313 rdf:type schema:CreativeWork
314 https://www.grid.ac/institutes/grid.266100.3 schema:alternateName University of California, San Diego
315 schema:name Department of Pathology, University of California at San Diego, La Jolla, California, CA 92093, USA
316 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...