Differential sensitivity of c-Fos expression in hippocampus and other brain regions to moderate and low doses of alcohol View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-01

AUTHORS

A E Ryabinin, J R Criado, S J Henriksen, F E Bloom, M C Wilson

ABSTRACT

Alcohol consumption in humans is characterized by a wide range of behavioral effects and pathological consequences that suggest several neuroanatomical targets for this drug. To identify these targets we have mapped alcohol-induced changes in the expression of the c-Fos protein in the rat brain. Administration of a moderate dose of alcohol (1.5 g kg−1) led to a suppression of basal and novel environment-induced c-Fos expression in the hippocampus and simultaneous induction of this protein in regions important for the reinforcing as well as aversive properties of drugs. These include the extended amygdala (including the central nucleus of amygdala, bed nucleus of stria terminalis and nucleus accumbens), regions processing sensory information (including the Edinger–Westphal nucleus and the paraventricular nucleus of the thalamus) and in stress-related areas (including the paraventricular nucleus of the hypothalamus, nucleus of the solitary tract and several neocortical areas). Repeated administration of the same dose of alcohol did not decrease alcohol-mediated suppression of c-Fos in the hippocampus, but decreased alcohol-induced expression of c-Fos in other areas. A lower dose of acute alcohol (0.5 g kg−1) reduced basal c-Fos expression in several areas of the neocortex, hippocampus and hypothalamus. However, while this low dose of alcohol was unable to counteract the environmental novelty-induced c-Fos expression in these areas, it increased c-Fos expression in the central nucleus of amygdala (an effect similar to the one observed previously for diazepam). Our data suggest that the effects of low doses of alcohol may be due to selective GABA-like effects of ethanol, whereas higher doses of ethanol involve effects on multiple neurotransmitter systems. More... »

PAGES

32-43

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.mp.4000206

DOI

http://dx.doi.org/10.1038/sj.mp.4000206

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026137718

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9154216


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dose-Response Relationship, Drug", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ethanol", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hippocampus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogene Proteins c-fos", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Sprague-Dawley", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sensitivity and Specificity", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Behavioral Neuroscience, L470, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, 97201, Portland, OR, USA", 
          "id": "http://www.grid.ac/institutes/grid.5288.7", 
          "name": [
            "Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA", 
            "Department of Behavioral Neuroscience, L470, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, 97201, Portland, OR, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ryabinin", 
        "givenName": "A E", 
        "id": "sg:person.01023600064.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023600064.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.214007.0", 
          "name": [
            "Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Criado", 
        "givenName": "J R", 
        "id": "sg:person.01366413345.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366413345.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.214007.0", 
          "name": [
            "Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Henriksen", 
        "givenName": "S J", 
        "id": "sg:person.01101162402.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101162402.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.214007.0", 
          "name": [
            "Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bloom", 
        "givenName": "F E", 
        "id": "sg:person.015435642037.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015435642037.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dept of Biochemistry, University of New Mexico School of Medicine, BMSF-249, 915 Camino del Salud, 87131, Albuquerque, NM, USA", 
          "id": "http://www.grid.ac/institutes/grid.266832.b", 
          "name": [
            "Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA", 
            "Dept of Biochemistry, University of New Mexico School of Medicine, BMSF-249, 915 Camino del Salud, 87131, Albuquerque, NM, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wilson", 
        "givenName": "M C", 
        "id": "sg:person.01110715057.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110715057.57"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00436101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034064179", 
          "https://doi.org/10.1007/bf00436101"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.3758/bf03212315", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048253607", 
          "https://doi.org/10.3758/bf03212315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4899-1684-6_5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000922342", 
          "https://doi.org/10.1007/978-1-4899-1684-6_5"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1997-01", 
    "datePublishedReg": "1997-01-01", 
    "description": "Alcohol consumption in humans is characterized by a wide range of behavioral effects and pathological consequences that suggest several neuroanatomical targets for this drug. To identify these targets we have mapped alcohol-induced changes in the expression of the c-Fos protein in the rat brain. Administration of a moderate dose of alcohol (1.5\u2009g\u2009kg\u22121) led to a suppression of basal and novel environment-induced c-Fos expression in the hippocampus and simultaneous induction of this protein in regions important for the reinforcing as well as aversive properties of drugs. These include the extended amygdala (including the central nucleus of amygdala, bed nucleus of stria terminalis and nucleus accumbens), regions processing sensory information (including the Edinger\u2013Westphal nucleus and the paraventricular nucleus of the thalamus) and in stress-related areas (including the paraventricular nucleus of the hypothalamus, nucleus of the solitary tract and several neocortical areas). Repeated administration of the same dose of alcohol did not decrease alcohol-mediated suppression of c-Fos in the hippocampus, but decreased alcohol-induced expression of c-Fos in other areas. A lower dose of acute alcohol (0.5\u2009g\u2009kg\u22121) reduced basal c-Fos expression in several areas of the neocortex, hippocampus and hypothalamus. However, while this low dose of alcohol was unable to counteract the environmental novelty-induced c-Fos expression in these areas, it increased c-Fos expression in the central nucleus of amygdala (an effect similar to the one observed previously for diazepam). Our data suggest that the effects of low doses of alcohol may be due to selective GABA-like effects of ethanol, whereas higher doses of ethanol involve effects on multiple neurotransmitter systems.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/sj.mp.4000206", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2439983", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2441141", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2483827", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1115540", 
        "issn": [
          "1359-4184", 
          "1476-5578"
        ], 
        "name": "Molecular Psychiatry", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "2"
      }
    ], 
    "keywords": [
      "Fos expression", 
      "low dose", 
      "low doses", 
      "alcohol-mediated suppression", 
      "GABA-like effect", 
      "stress-related areas", 
      "alcohol-induced changes", 
      "alcohol-induced expression", 
      "multiple neurotransmitter systems", 
      "acute alcohol", 
      "Repeated administration", 
      "moderate dose", 
      "extended amygdala", 
      "neurotransmitter systems", 
      "same dose", 
      "neuroanatomical targets", 
      "rat brain", 
      "high doses", 
      "alcohol consumption", 
      "central nucleus", 
      "brain regions", 
      "hippocampus", 
      "aversive properties", 
      "behavioral effects", 
      "dose", 
      "Fos protein", 
      "basal c", 
      "pathological consequences", 
      "doses", 
      "amygdala", 
      "administration", 
      "differential sensitivity", 
      "drugs", 
      "simultaneous induction", 
      "sensory information", 
      "expression", 
      "Fos", 
      "suppression", 
      "neocortex", 
      "brain", 
      "alcohol", 
      "effect", 
      "target", 
      "induction", 
      "protein", 
      "humans", 
      "area", 
      "sensitivity", 
      "nucleus", 
      "ethanol", 
      "changes", 
      "region", 
      "data", 
      "consequences", 
      "consumption", 
      "wide range", 
      "information", 
      "range", 
      "system", 
      "properties", 
      "selective GABA-like effects"
    ], 
    "name": "Differential sensitivity of c-Fos expression in hippocampus and other brain regions to moderate and low doses of alcohol", 
    "pagination": "32-43", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1026137718"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.mp.4000206"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "9154216"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.mp.4000206", 
      "https://app.dimensions.ai/details/publication/pub.1026137718"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T18:02", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_293.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/sj.mp.4000206"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.mp.4000206'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.mp.4000206'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.mp.4000206'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.mp.4000206'


 

This table displays all metadata directly associated to this object as RDF triples.

217 TRIPLES      22 PREDICATES      101 URIs      90 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.mp.4000206 schema:about N152d6b9b21ed4d38a6adebb80b70bf08
2 N3e4054af439b43c28415ad0f4f29d17b
3 N442c1861c306492184ef8af3f7ec6f7e
4 N466a467836204107a5358b6cabdf4213
5 N52a29a9abb114a3b8253379774a481ea
6 N5ee9adc019244ddeaec45e4ce4529361
7 N812bf9af8932498e9c7f1503c5862b42
8 Na588b81a4dce4683b48ffaf7b1008575
9 Ndd0caf3fe0b64abfb271c25a2c079f2f
10 Nfa668d0f796340159cfacf60f15bc127
11 anzsrc-for:11
12 anzsrc-for:1109
13 schema:author Nbf3a275e46d24b3cb172d042b1cd7323
14 schema:citation sg:pub.10.1007/978-1-4899-1684-6_5
15 sg:pub.10.1007/bf00436101
16 sg:pub.10.3758/bf03212315
17 schema:datePublished 1997-01
18 schema:datePublishedReg 1997-01-01
19 schema:description Alcohol consumption in humans is characterized by a wide range of behavioral effects and pathological consequences that suggest several neuroanatomical targets for this drug. To identify these targets we have mapped alcohol-induced changes in the expression of the c-Fos protein in the rat brain. Administration of a moderate dose of alcohol (1.5 g kg−1) led to a suppression of basal and novel environment-induced c-Fos expression in the hippocampus and simultaneous induction of this protein in regions important for the reinforcing as well as aversive properties of drugs. These include the extended amygdala (including the central nucleus of amygdala, bed nucleus of stria terminalis and nucleus accumbens), regions processing sensory information (including the Edinger–Westphal nucleus and the paraventricular nucleus of the thalamus) and in stress-related areas (including the paraventricular nucleus of the hypothalamus, nucleus of the solitary tract and several neocortical areas). Repeated administration of the same dose of alcohol did not decrease alcohol-mediated suppression of c-Fos in the hippocampus, but decreased alcohol-induced expression of c-Fos in other areas. A lower dose of acute alcohol (0.5 g kg−1) reduced basal c-Fos expression in several areas of the neocortex, hippocampus and hypothalamus. However, while this low dose of alcohol was unable to counteract the environmental novelty-induced c-Fos expression in these areas, it increased c-Fos expression in the central nucleus of amygdala (an effect similar to the one observed previously for diazepam). Our data suggest that the effects of low doses of alcohol may be due to selective GABA-like effects of ethanol, whereas higher doses of ethanol involve effects on multiple neurotransmitter systems.
20 schema:genre article
21 schema:inLanguage en
22 schema:isAccessibleForFree false
23 schema:isPartOf Nb7a58b22a01b4d6b95ce3cd1e9613794
24 Nbf40a0caec4041a08a6918bb1ff768f1
25 sg:journal.1115540
26 schema:keywords Fos
27 Fos expression
28 Fos protein
29 GABA-like effect
30 Repeated administration
31 acute alcohol
32 administration
33 alcohol
34 alcohol consumption
35 alcohol-induced changes
36 alcohol-induced expression
37 alcohol-mediated suppression
38 amygdala
39 area
40 aversive properties
41 basal c
42 behavioral effects
43 brain
44 brain regions
45 central nucleus
46 changes
47 consequences
48 consumption
49 data
50 differential sensitivity
51 dose
52 doses
53 drugs
54 effect
55 ethanol
56 expression
57 extended amygdala
58 high doses
59 hippocampus
60 humans
61 induction
62 information
63 low dose
64 low doses
65 moderate dose
66 multiple neurotransmitter systems
67 neocortex
68 neuroanatomical targets
69 neurotransmitter systems
70 nucleus
71 pathological consequences
72 properties
73 protein
74 range
75 rat brain
76 region
77 same dose
78 selective GABA-like effects
79 sensitivity
80 sensory information
81 simultaneous induction
82 stress-related areas
83 suppression
84 system
85 target
86 wide range
87 schema:name Differential sensitivity of c-Fos expression in hippocampus and other brain regions to moderate and low doses of alcohol
88 schema:pagination 32-43
89 schema:productId N37c8ee36136943b38fa25bd4b1ce2d39
90 N63a09c09c4ee40e0aa349fcf15822836
91 Nc93e6d1ba6cd48c795b38e7f354cc6df
92 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026137718
93 https://doi.org/10.1038/sj.mp.4000206
94 schema:sdDatePublished 2021-11-01T18:02
95 schema:sdLicense https://scigraph.springernature.com/explorer/license/
96 schema:sdPublisher N2e5c471fa7d64f71aea4e861e39fdadd
97 schema:url https://doi.org/10.1038/sj.mp.4000206
98 sgo:license sg:explorer/license/
99 sgo:sdDataset articles
100 rdf:type schema:ScholarlyArticle
101 N118c420135d9448b8e4071c3cab72ca3 rdf:first sg:person.01366413345.82
102 rdf:rest N894d2baa7f9547ebbc5436602528669d
103 N152d6b9b21ed4d38a6adebb80b70bf08 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Rats
105 rdf:type schema:DefinedTerm
106 N20ea6131fe8f452389fc9b0242b680fa rdf:first sg:person.015435642037.30
107 rdf:rest N314d1c99185a4af383f4b2886433bf8d
108 N2e5c471fa7d64f71aea4e861e39fdadd schema:name Springer Nature - SN SciGraph project
109 rdf:type schema:Organization
110 N314d1c99185a4af383f4b2886433bf8d rdf:first sg:person.01110715057.57
111 rdf:rest rdf:nil
112 N37c8ee36136943b38fa25bd4b1ce2d39 schema:name pubmed_id
113 schema:value 9154216
114 rdf:type schema:PropertyValue
115 N3e4054af439b43c28415ad0f4f29d17b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Proto-Oncogene Proteins c-fos
117 rdf:type schema:DefinedTerm
118 N442c1861c306492184ef8af3f7ec6f7e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Ethanol
120 rdf:type schema:DefinedTerm
121 N466a467836204107a5358b6cabdf4213 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Sensitivity and Specificity
123 rdf:type schema:DefinedTerm
124 N52a29a9abb114a3b8253379774a481ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Dose-Response Relationship, Drug
126 rdf:type schema:DefinedTerm
127 N5ee9adc019244ddeaec45e4ce4529361 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Animals
129 rdf:type schema:DefinedTerm
130 N63a09c09c4ee40e0aa349fcf15822836 schema:name doi
131 schema:value 10.1038/sj.mp.4000206
132 rdf:type schema:PropertyValue
133 N812bf9af8932498e9c7f1503c5862b42 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Rats, Sprague-Dawley
135 rdf:type schema:DefinedTerm
136 N894d2baa7f9547ebbc5436602528669d rdf:first sg:person.01101162402.15
137 rdf:rest N20ea6131fe8f452389fc9b0242b680fa
138 Na588b81a4dce4683b48ffaf7b1008575 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Brain
140 rdf:type schema:DefinedTerm
141 Nb7a58b22a01b4d6b95ce3cd1e9613794 schema:issueNumber 1
142 rdf:type schema:PublicationIssue
143 Nbf3a275e46d24b3cb172d042b1cd7323 rdf:first sg:person.01023600064.15
144 rdf:rest N118c420135d9448b8e4071c3cab72ca3
145 Nbf40a0caec4041a08a6918bb1ff768f1 schema:volumeNumber 2
146 rdf:type schema:PublicationVolume
147 Nc93e6d1ba6cd48c795b38e7f354cc6df schema:name dimensions_id
148 schema:value pub.1026137718
149 rdf:type schema:PropertyValue
150 Ndd0caf3fe0b64abfb271c25a2c079f2f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Hippocampus
152 rdf:type schema:DefinedTerm
153 Nfa668d0f796340159cfacf60f15bc127 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Male
155 rdf:type schema:DefinedTerm
156 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
157 schema:name Medical and Health Sciences
158 rdf:type schema:DefinedTerm
159 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
160 schema:name Neurosciences
161 rdf:type schema:DefinedTerm
162 sg:grant.2439983 http://pending.schema.org/fundedItem sg:pub.10.1038/sj.mp.4000206
163 rdf:type schema:MonetaryGrant
164 sg:grant.2441141 http://pending.schema.org/fundedItem sg:pub.10.1038/sj.mp.4000206
165 rdf:type schema:MonetaryGrant
166 sg:grant.2483827 http://pending.schema.org/fundedItem sg:pub.10.1038/sj.mp.4000206
167 rdf:type schema:MonetaryGrant
168 sg:journal.1115540 schema:issn 1359-4184
169 1476-5578
170 schema:name Molecular Psychiatry
171 schema:publisher Springer Nature
172 rdf:type schema:Periodical
173 sg:person.01023600064.15 schema:affiliation grid-institutes:grid.5288.7
174 schema:familyName Ryabinin
175 schema:givenName A E
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023600064.15
177 rdf:type schema:Person
178 sg:person.01101162402.15 schema:affiliation grid-institutes:grid.214007.0
179 schema:familyName Henriksen
180 schema:givenName S J
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101162402.15
182 rdf:type schema:Person
183 sg:person.01110715057.57 schema:affiliation grid-institutes:grid.266832.b
184 schema:familyName Wilson
185 schema:givenName M C
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110715057.57
187 rdf:type schema:Person
188 sg:person.01366413345.82 schema:affiliation grid-institutes:grid.214007.0
189 schema:familyName Criado
190 schema:givenName J R
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366413345.82
192 rdf:type schema:Person
193 sg:person.015435642037.30 schema:affiliation grid-institutes:grid.214007.0
194 schema:familyName Bloom
195 schema:givenName F E
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015435642037.30
197 rdf:type schema:Person
198 sg:pub.10.1007/978-1-4899-1684-6_5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000922342
199 https://doi.org/10.1007/978-1-4899-1684-6_5
200 rdf:type schema:CreativeWork
201 sg:pub.10.1007/bf00436101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034064179
202 https://doi.org/10.1007/bf00436101
203 rdf:type schema:CreativeWork
204 sg:pub.10.3758/bf03212315 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048253607
205 https://doi.org/10.3758/bf03212315
206 rdf:type schema:CreativeWork
207 grid-institutes:grid.214007.0 schema:alternateName Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA
208 schema:name Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA
209 rdf:type schema:Organization
210 grid-institutes:grid.266832.b schema:alternateName Dept of Biochemistry, University of New Mexico School of Medicine, BMSF-249, 915 Camino del Salud, 87131, Albuquerque, NM, USA
211 schema:name Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA
212 Dept of Biochemistry, University of New Mexico School of Medicine, BMSF-249, 915 Camino del Salud, 87131, Albuquerque, NM, USA
213 rdf:type schema:Organization
214 grid-institutes:grid.5288.7 schema:alternateName Department of Behavioral Neuroscience, L470, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, 97201, Portland, OR, USA
215 schema:name Department of Behavioral Neuroscience, L470, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, 97201, Portland, OR, USA
216 Department of Neuropharmacology, Alcohol Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA
217 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...