Results of 58872 and 58921 trials in acute myeloblastic leukemia and relative value of chemotherapy vs allogeneic bone marrow transplantation ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2005-12

AUTHORS

N Entz-Werle, S Suciu, J van der Werff ten Bosch, E Vilmer, Y Bertrand, Y Benoit, G Margueritte, E Plouvier, P Boutard, E Vandecruys, A Ferster, P Lutz, A Uyttebroeck, C Hoyoux, A Thyss, X Rialland, L Norton, M-P Pages, N Philippe, J Otten, C Behar

ABSTRACT

The first EORTC (European Organization of Research and Treatment of Cancer) acute myeloblastic leukemia (AML) pilot study (58872) was conducted between January 1988 and December 1991. Out of 108 patients, 78% achieved complete remission (CR), and event-free survival (EFS) and survival rates (s.e., %) at 7 years were 40 (5) and 51% (6%), respectively. It indicated that mitoxantrone could be substituted for conventional anthracyclines in the treatment of childhood AML without inducing cardiotoxicity. The aim of the next EORTC 58921 trial was to compare the efficacy and toxicity of idarubicin vs mitoxantrone in initial chemotherapy courses, further therapy consisting of allogeneic bone marrow transplantation (alloBMT) in patients with an HLA-compatible sibling donor or chemotherapy in patients without a donor. Out of 177 patients, recruited between October 1992 and December 2002, 81% reached CR. Overall 7-year EFS and survival rates were 49 (4) and 62% (4%), respectively. Out of 145 patients who received the first intensification, 39 had a sibling donor. In patients with or without a donor, the 7-year disease-free survival (DFS) rate was 63 (8) and 57% (5%) and the 7-year survival rate was 78 (7) and 65% (5%), respectively. Patients with favorable, intermediate and unfavorable cytogenetic features had a 5-year EFS rate of 57, 45 and 45% and a 5-year survival rate of 89, 67 and 53%, respectively. More... »

PAGES

2072

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.leu.2403932

DOI

http://dx.doi.org/10.1038/sj.leu.2403932

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053019280

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16136166


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antineoplastic Combined Chemotherapy Protocols", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antineoplastic Protocols", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Marrow Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child, Preschool", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Idarubicin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant, Newborn", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Leukemia, Myeloid, Acute", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mitoxantrone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Remission Induction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation, Homologous", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Pediatrics, Hautepierre, Strasbourg, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Entz-Werle", 
        "givenName": "N", 
        "id": "sg:person.01336011345.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336011345.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "European Organisation for Research and Treatment of Cancer", 
          "id": "https://www.grid.ac/institutes/grid.418936.1", 
          "name": [
            "EORTC Data Center, Brussels, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suciu", 
        "givenName": "S", 
        "id": "sg:person.01014211567.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014211567.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vrije Universiteit Brussel", 
          "id": "https://www.grid.ac/institutes/grid.8767.e", 
          "name": [
            "Department of Pediatrics, Academisch Ziekenhuis-VUB, Brussels, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van der Werff ten Bosch", 
        "givenName": "J", 
        "id": "sg:person.011047615427.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011047615427.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Robert Debr\u00e9", 
          "id": "https://www.grid.ac/institutes/grid.413235.2", 
          "name": [
            "Department of Hemato-Immunology, Robert Debr\u00e9 Hospital, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vilmer", 
        "givenName": "E", 
        "id": "sg:person.01164751365.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01164751365.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Debrousse", 
          "id": "https://www.grid.ac/institutes/grid.413959.3", 
          "name": [
            "Department of Immuno-Hemato-Pediatrics, Debrousse Hospital, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bertrand", 
        "givenName": "Y", 
        "id": "sg:person.01077622701.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077622701.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatric Hemato-Oncology, Universitair Kinderziekenhuis, Gent, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Benoit", 
        "givenName": "Y", 
        "id": "sg:person.0656150614.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656150614.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Arnaud De Villeneuve", 
          "id": "https://www.grid.ac/institutes/grid.413745.0", 
          "name": [
            "Department of Onco-Hematology, Arnaud de Villeneuve Hospital, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Margueritte", 
        "givenName": "G", 
        "id": "sg:person.0653007001.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653007001.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Saint-Jacques", 
          "id": "https://www.grid.ac/institutes/grid.414362.6", 
          "name": [
            "Department of Pediatric Hematology, Saint-Jacques Hospital, Besan\u00e7on, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Plouvier", 
        "givenName": "E", 
        "id": "sg:person.015211451707.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015211451707.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Caen", 
          "id": "https://www.grid.ac/institutes/grid.411149.8", 
          "name": [
            "Department of Pediatrics, CHRU, Caen, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boutard", 
        "givenName": "P", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatric Hemato-Oncology, Universitair Kinderziekenhuis, Gent, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vandecruys", 
        "givenName": "E", 
        "id": "sg:person.01204466035.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204466035.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Hemato-Oncology, HUDE, Brussels, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ferster", 
        "givenName": "A", 
        "id": "sg:person.010455515057.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010455515057.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatrics, Hautepierre, Strasbourg, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lutz", 
        "givenName": "P", 
        "id": "sg:person.0632623045.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632623045.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universitaire Ziekenhuizen Leuven", 
          "id": "https://www.grid.ac/institutes/grid.410569.f", 
          "name": [
            "Department of Pediatric Hemato-Oncology, UZ Gasthuisberg, Leuven, Belgique"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uyttebroeck", 
        "givenName": "A", 
        "id": "sg:person.01213352014.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213352014.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre hospitalier r\u00e9gional de la Citadelle", 
          "id": "https://www.grid.ac/institutes/grid.413914.a", 
          "name": [
            "Department of Hematology, CHR de la Citadelle, Li\u00e8ge, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hoyoux", 
        "givenName": "C", 
        "id": "sg:person.01345145264.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01345145264.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Hemato-Oncology, Antoine Lacassagne Center, Nice, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thyss", 
        "givenName": "A", 
        "id": "sg:person.01214171600.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214171600.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Angers", 
          "id": "https://www.grid.ac/institutes/grid.411147.6", 
          "name": [
            "Department of Pediatric Hemato-Oncology, CHRU, Angers, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rialland", 
        "givenName": "X", 
        "id": "sg:person.01057654417.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057654417.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatric Hemato-Oncology, Escolar San Joao Hospital, Porto, Portugal"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Norton", 
        "givenName": "L", 
        "id": "sg:person.0702212261.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702212261.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Debrousse", 
          "id": "https://www.grid.ac/institutes/grid.413959.3", 
          "name": [
            "Department of Immuno-Hemato-Pediatrics, Debrousse Hospital, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pages", 
        "givenName": "M-P", 
        "id": "sg:person.0601705620.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601705620.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Debrousse", 
          "id": "https://www.grid.ac/institutes/grid.413959.3", 
          "name": [
            "Department of Immuno-Hemato-Pediatrics, Debrousse Hospital, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Philippe", 
        "givenName": "N", 
        "id": "sg:person.01155247165.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155247165.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Vrije Universiteit Brussel", 
          "id": "https://www.grid.ac/institutes/grid.8767.e", 
          "name": [
            "Department of Pediatrics, Academisch Ziekenhuis-VUB, Brussels, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Otten", 
        "givenName": "J", 
        "id": "sg:person.0637705213.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637705213.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Pediatric Hematology, American Hospital, Reims, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Behar", 
        "givenName": "C", 
        "id": "sg:person.01261521622.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261521622.02"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.leu.2402390", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001669761", 
          "https://doi.org/10.1038/sj.leu.2402390"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2402390", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001669761", 
          "https://doi.org/10.1038/sj.leu.2402390"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2403958", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005963124", 
          "https://doi.org/10.1038/sj.leu.2403958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2403958", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005963124", 
          "https://doi.org/10.1038/sj.leu.2403958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2403958", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005963124", 
          "https://doi.org/10.1038/sj.leu.2403958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2402782", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010836635", 
          "https://doi.org/10.1038/sj.leu.2402782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2402782", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010836635", 
          "https://doi.org/10.1038/sj.leu.2402782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-72624-8_6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013324934", 
          "https://doi.org/10.1007/978-3-642-72624-8_6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-911x(199603)26:3<173::aid-mpo5>3.0.co;2-h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019116120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2401832", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019434822", 
          "https://doi.org/10.1038/sj.leu.2401832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2401832", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019434822", 
          "https://doi.org/10.1038/sj.leu.2401832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(97)09214-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020730183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002770050148", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020829719", 
          "https://doi.org/10.1007/s002770050148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2002-03-0772", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024049275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2141.1991.tb04444.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045844708"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2002.08.023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064203108"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2002.08.023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064203108"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-103-4-620", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073690404"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074737871", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2001.19.10.2705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074814015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077372838", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077660802", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1991.9.4.572", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078193751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1990.8.5.813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078438169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078440483", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078475282", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1989.7.9.1260", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079333928"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079589299", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080011790", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1993.11.8.1448", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082762674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082895213", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082997511", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083319627", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2005-12", 
    "datePublishedReg": "2005-12-01", 
    "description": "The first EORTC (European Organization of Research and Treatment of Cancer) acute myeloblastic leukemia (AML) pilot study (58872) was conducted between January 1988 and December 1991. Out of 108 patients, 78% achieved complete remission (CR), and event-free survival (EFS) and survival rates (s.e., %) at 7 years were 40 (5) and 51% (6%), respectively. It indicated that mitoxantrone could be substituted for conventional anthracyclines in the treatment of childhood AML without inducing cardiotoxicity. The aim of the next EORTC 58921 trial was to compare the efficacy and toxicity of idarubicin vs mitoxantrone in initial chemotherapy courses, further therapy consisting of allogeneic bone marrow transplantation (alloBMT) in patients with an HLA-compatible sibling donor or chemotherapy in patients without a donor. Out of 177 patients, recruited between October 1992 and December 2002, 81% reached CR. Overall 7-year EFS and survival rates were 49 (4) and 62% (4%), respectively. Out of 145 patients who received the first intensification, 39 had a sibling donor. In patients with or without a donor, the 7-year disease-free survival (DFS) rate was 63 (8) and 57% (5%) and the 7-year survival rate was 78 (7) and 65% (5%), respectively. Patients with favorable, intermediate and unfavorable cytogenetic features had a 5-year EFS rate of 57, 45 and 45% and a 5-year survival rate of 89, 67 and 53%, respectively.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/sj.leu.2403932", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2693192", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1097065", 
        "issn": [
          "0887-6924", 
          "1476-5551"
        ], 
        "name": "Leukemia", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "12", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "19"
      }
    ], 
    "name": "Results of 58872 and 58921 trials in acute myeloblastic leukemia and relative value of chemotherapy vs allogeneic bone marrow transplantation in first complete remission: the EORTC Children Leukemia Group report", 
    "pagination": "2072", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "fc8be0ce61bb58f68fbe455d0303ea21b0c66d1ed18e6c2a6219e78a9fb7677e"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "16136166"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8704895"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.leu.2403932"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1053019280"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.leu.2403932", 
      "https://app.dimensions.ai/details/publication/pub.1053019280"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:04", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000360_0000000360/records_118315_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/2403932"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.leu.2403932'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.leu.2403932'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.leu.2403932'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.leu.2403932'


 

This table displays all metadata directly associated to this object as RDF triples.

402 TRIPLES      21 PREDICATES      74 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.leu.2403932 schema:about N14e8870d58604345bfde95cc3b11f755
2 N2a3c41a5d0f140e1af115cf43273a602
3 N314195e37bc34b4294c010dc1d748498
4 N6d33c0d90b2b4b488e1b19a3398eb5c2
5 N8c0c428054944f3cba90355df419b673
6 N9161d19a79734d0aae706a40d4e816a7
7 N927acce9e4f041e79a9e53a300936a97
8 N93f5be9e44d94c0d8463a888cc792e78
9 Nb8f6b9c7bf4f40e5b141648601d9ad1e
10 Nc512031106ac4851835c7b59ba047d86
11 Nda33177aecfb408e8b384d495de73ae9
12 Ne5879ec9db0c4324b19e057672f4331d
13 Ne631d11e3db94a9c8236b351b311f5f0
14 Ne66581258ac84f84846f6b76d6a13447
15 Ne7c597679dbe422aad8e8c5fc4816a30
16 Nee1bea20661a40a7833e2fd7f7734908
17 Neee5e17c8c29446d8a37c31b7b114685
18 Nf2a2123fbdad4dde850a4afb0188fb42
19 anzsrc-for:11
20 anzsrc-for:1112
21 schema:author N362a4f1d812a4c6e8ac474da556bb668
22 schema:citation sg:pub.10.1007/978-3-642-72624-8_6
23 sg:pub.10.1007/s002770050148
24 sg:pub.10.1038/sj.leu.2401832
25 sg:pub.10.1038/sj.leu.2402390
26 sg:pub.10.1038/sj.leu.2402782
27 sg:pub.10.1038/sj.leu.2403958
28 https://app.dimensions.ai/details/publication/pub.1074737871
29 https://app.dimensions.ai/details/publication/pub.1077372838
30 https://app.dimensions.ai/details/publication/pub.1077660802
31 https://app.dimensions.ai/details/publication/pub.1078440483
32 https://app.dimensions.ai/details/publication/pub.1078475282
33 https://app.dimensions.ai/details/publication/pub.1079589299
34 https://app.dimensions.ai/details/publication/pub.1080011790
35 https://app.dimensions.ai/details/publication/pub.1082895213
36 https://app.dimensions.ai/details/publication/pub.1082997511
37 https://app.dimensions.ai/details/publication/pub.1083319627
38 https://doi.org/10.1002/(sici)1096-911x(199603)26:3<173::aid-mpo5>3.0.co;2-h
39 https://doi.org/10.1016/s0140-6736(97)09214-3
40 https://doi.org/10.1111/j.1365-2141.1991.tb04444.x
41 https://doi.org/10.1182/blood-2002-03-0772
42 https://doi.org/10.1200/jco.1989.7.9.1260
43 https://doi.org/10.1200/jco.1990.8.5.813
44 https://doi.org/10.1200/jco.1991.9.4.572
45 https://doi.org/10.1200/jco.1993.11.8.1448
46 https://doi.org/10.1200/jco.2001.19.10.2705
47 https://doi.org/10.1200/jco.2002.08.023
48 https://doi.org/10.7326/0003-4819-103-4-620
49 schema:datePublished 2005-12
50 schema:datePublishedReg 2005-12-01
51 schema:description The first EORTC (European Organization of Research and Treatment of Cancer) acute myeloblastic leukemia (AML) pilot study (58872) was conducted between January 1988 and December 1991. Out of 108 patients, 78% achieved complete remission (CR), and event-free survival (EFS) and survival rates (s.e., %) at 7 years were 40 (5) and 51% (6%), respectively. It indicated that mitoxantrone could be substituted for conventional anthracyclines in the treatment of childhood AML without inducing cardiotoxicity. The aim of the next EORTC 58921 trial was to compare the efficacy and toxicity of idarubicin vs mitoxantrone in initial chemotherapy courses, further therapy consisting of allogeneic bone marrow transplantation (alloBMT) in patients with an HLA-compatible sibling donor or chemotherapy in patients without a donor. Out of 177 patients, recruited between October 1992 and December 2002, 81% reached CR. Overall 7-year EFS and survival rates were 49 (4) and 62% (4%), respectively. Out of 145 patients who received the first intensification, 39 had a sibling donor. In patients with or without a donor, the 7-year disease-free survival (DFS) rate was 63 (8) and 57% (5%) and the 7-year survival rate was 78 (7) and 65% (5%), respectively. Patients with favorable, intermediate and unfavorable cytogenetic features had a 5-year EFS rate of 57, 45 and 45% and a 5-year survival rate of 89, 67 and 53%, respectively.
52 schema:genre research_article
53 schema:inLanguage en
54 schema:isAccessibleForFree true
55 schema:isPartOf N15ee94a716bf4561bc3a14f6b0eabaf4
56 N5e94b57e2178402f9abc45968c5fbf1d
57 sg:journal.1097065
58 schema:name Results of 58872 and 58921 trials in acute myeloblastic leukemia and relative value of chemotherapy vs allogeneic bone marrow transplantation in first complete remission: the EORTC Children Leukemia Group report
59 schema:pagination 2072
60 schema:productId N1f40a6bfe30c4835b34dac30a8b0a79c
61 N5b5792b0c0cf41608ce7f53857730fc2
62 N5d81d747d4f94e2d9438fd6b6e2dbcea
63 Nb9196e0f6ad34bcbb733bebef141ad14
64 Nc7f8a4ab3d3a4ac4899b6670ba7136cb
65 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053019280
66 https://doi.org/10.1038/sj.leu.2403932
67 schema:sdDatePublished 2019-04-11T12:04
68 schema:sdLicense https://scigraph.springernature.com/explorer/license/
69 schema:sdPublisher Nb9ba5039411448b4a2700724c3cacb7a
70 schema:url https://www.nature.com/articles/2403932
71 sgo:license sg:explorer/license/
72 sgo:sdDataset articles
73 rdf:type schema:ScholarlyArticle
74 N0e1e10566038482f9784157e6c806183 rdf:first sg:person.01261521622.02
75 rdf:rest rdf:nil
76 N14e8870d58604345bfde95cc3b11f755 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Infant
78 rdf:type schema:DefinedTerm
79 N15ee94a716bf4561bc3a14f6b0eabaf4 schema:issueNumber 12
80 rdf:type schema:PublicationIssue
81 N186998a256f54a9182b0985876dfb229 rdf:first sg:person.015211451707.05
82 rdf:rest Nb5660a5d83ea4af4a5914fcf33e4fe6c
83 N1f40a6bfe30c4835b34dac30a8b0a79c schema:name pubmed_id
84 schema:value 16136166
85 rdf:type schema:PropertyValue
86 N2a1e8ed8ae2542d9a819deff5db9df6f rdf:first sg:person.010455515057.22
87 rdf:rest Nf50869da57f04e5f89da33f482dbf4bb
88 N2a3c41a5d0f140e1af115cf43273a602 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Transplantation, Homologous
90 rdf:type schema:DefinedTerm
91 N2de039c4ec9a4161a0bc4faecad70f3d rdf:first sg:person.0637705213.34
92 rdf:rest N0e1e10566038482f9784157e6c806183
93 N2df1f56c0f9c44ccb1b1023a3d0e0b70 schema:name Department of Pediatric Hemato-Oncology, Escolar San Joao Hospital, Porto, Portugal
94 rdf:type schema:Organization
95 N314195e37bc34b4294c010dc1d748498 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Remission Induction
97 rdf:type schema:DefinedTerm
98 N362a4f1d812a4c6e8ac474da556bb668 rdf:first sg:person.01336011345.47
99 rdf:rest Nc6aa95a4b2a54ea3a3c5d6a79e513518
100 N48b56a2e1aab4763978891331fc56b86 schema:name Department of Pediatric Hematology, American Hospital, Reims, France
101 rdf:type schema:Organization
102 N5003badf4d9b4464a5184bc3527983d8 schema:name Department of Hemato-Oncology, HUDE, Brussels, Belgium
103 rdf:type schema:Organization
104 N540a9efc920549deafab98d2e57e90a7 rdf:first sg:person.0601705620.18
105 rdf:rest Ne2f5c29c1a6e4113a0b24a032d00e6e2
106 N59a0bc16b4204c92a5293e488ad6570c schema:name Department of Pediatrics, Hautepierre, Strasbourg, France
107 rdf:type schema:Organization
108 N5b5792b0c0cf41608ce7f53857730fc2 schema:name dimensions_id
109 schema:value pub.1053019280
110 rdf:type schema:PropertyValue
111 N5d81d747d4f94e2d9438fd6b6e2dbcea schema:name doi
112 schema:value 10.1038/sj.leu.2403932
113 rdf:type schema:PropertyValue
114 N5e94b57e2178402f9abc45968c5fbf1d schema:volumeNumber 19
115 rdf:type schema:PublicationVolume
116 N694f3cc400fe4b7e8fed881846091217 rdf:first sg:person.01164751365.30
117 rdf:rest N9018555fe7fe40aaa5b88b17f55cceed
118 N6b67bc2f8523496ab497fd919bb8bc76 rdf:first sg:person.0653007001.30
119 rdf:rest N186998a256f54a9182b0985876dfb229
120 N6d33c0d90b2b4b488e1b19a3398eb5c2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Mitoxantrone
122 rdf:type schema:DefinedTerm
123 N6e6d55f7cb2c4f4cb11eedbc201b42a6 rdf:first sg:person.01204466035.52
124 rdf:rest N2a1e8ed8ae2542d9a819deff5db9df6f
125 N7dfa94df22824696b0d055e162f5316a rdf:first sg:person.011047615427.27
126 rdf:rest N694f3cc400fe4b7e8fed881846091217
127 N7f3eb24d32304ab8a33a2df4edb24459 schema:name Department of Pediatric Hemato-Oncology, Universitair Kinderziekenhuis, Gent, Belgium
128 rdf:type schema:Organization
129 N8c0c428054944f3cba90355df419b673 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Idarubicin
131 rdf:type schema:DefinedTerm
132 N9018555fe7fe40aaa5b88b17f55cceed rdf:first sg:person.01077622701.25
133 rdf:rest Ndc71c9eda8d24c7c9e86fddc7c04ad6b
134 N9161d19a79734d0aae706a40d4e816a7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Follow-Up Studies
136 rdf:type schema:DefinedTerm
137 N927acce9e4f041e79a9e53a300936a97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Infant, Newborn
139 rdf:type schema:DefinedTerm
140 N93f5be9e44d94c0d8463a888cc792e78 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Female
142 rdf:type schema:DefinedTerm
143 N981b34e1a7bc4f0a9eb15f9c5774024d schema:name Department of Pediatric Hemato-Oncology, Universitair Kinderziekenhuis, Gent, Belgium
144 rdf:type schema:Organization
145 Naadc1f24f5d14eefa476f1b96c5b2664 schema:name Department of Pediatrics, Hautepierre, Strasbourg, France
146 rdf:type schema:Organization
147 Nb5660a5d83ea4af4a5914fcf33e4fe6c rdf:first Ne23f28dbce824df4aeb4f8eacf48f492
148 rdf:rest N6e6d55f7cb2c4f4cb11eedbc201b42a6
149 Nb8f6b9c7bf4f40e5b141648601d9ad1e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Leukemia, Myeloid, Acute
151 rdf:type schema:DefinedTerm
152 Nb9196e0f6ad34bcbb733bebef141ad14 schema:name readcube_id
153 schema:value fc8be0ce61bb58f68fbe455d0303ea21b0c66d1ed18e6c2a6219e78a9fb7677e
154 rdf:type schema:PropertyValue
155 Nb9ba5039411448b4a2700724c3cacb7a schema:name Springer Nature - SN SciGraph project
156 rdf:type schema:Organization
157 Nc360f10d83944a2a987c37626033b928 rdf:first sg:person.01345145264.83
158 rdf:rest Nd6c504dfe4bc421f974389f0fe2421c4
159 Nc512031106ac4851835c7b59ba047d86 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Child, Preschool
161 rdf:type schema:DefinedTerm
162 Nc6aa95a4b2a54ea3a3c5d6a79e513518 rdf:first sg:person.01014211567.13
163 rdf:rest N7dfa94df22824696b0d055e162f5316a
164 Nc7f8a4ab3d3a4ac4899b6670ba7136cb schema:name nlm_unique_id
165 schema:value 8704895
166 rdf:type schema:PropertyValue
167 Ncfdf513a3c814696b7f5949943a9769c rdf:first sg:person.01057654417.64
168 rdf:rest Nfcb5c03aa71d4c5588561f0fe607db02
169 Nd6c504dfe4bc421f974389f0fe2421c4 rdf:first sg:person.01214171600.00
170 rdf:rest Ncfdf513a3c814696b7f5949943a9769c
171 Nda33177aecfb408e8b384d495de73ae9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Survival Rate
173 rdf:type schema:DefinedTerm
174 Ndc71c9eda8d24c7c9e86fddc7c04ad6b rdf:first sg:person.0656150614.05
175 rdf:rest N6b67bc2f8523496ab497fd919bb8bc76
176 Ne23f28dbce824df4aeb4f8eacf48f492 schema:affiliation https://www.grid.ac/institutes/grid.411149.8
177 schema:familyName Boutard
178 schema:givenName P
179 rdf:type schema:Person
180 Ne2f5c29c1a6e4113a0b24a032d00e6e2 rdf:first sg:person.01155247165.08
181 rdf:rest N2de039c4ec9a4161a0bc4faecad70f3d
182 Ne5879ec9db0c4324b19e057672f4331d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Antineoplastic Combined Chemotherapy Protocols
184 rdf:type schema:DefinedTerm
185 Ne631d11e3db94a9c8236b351b311f5f0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Antineoplastic Protocols
187 rdf:type schema:DefinedTerm
188 Ne66581258ac84f84846f6b76d6a13447 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Adolescent
190 rdf:type schema:DefinedTerm
191 Ne7c597679dbe422aad8e8c5fc4816a30 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Humans
193 rdf:type schema:DefinedTerm
194 Neb5c675146304397a5434d96e6469cbc rdf:first sg:person.01213352014.94
195 rdf:rest Nc360f10d83944a2a987c37626033b928
196 Nee1bea20661a40a7833e2fd7f7734908 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Bone Marrow Transplantation
198 rdf:type schema:DefinedTerm
199 Neee5e17c8c29446d8a37c31b7b114685 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name Child
201 rdf:type schema:DefinedTerm
202 Nf2a2123fbdad4dde850a4afb0188fb42 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
203 schema:name Male
204 rdf:type schema:DefinedTerm
205 Nf50869da57f04e5f89da33f482dbf4bb rdf:first sg:person.0632623045.51
206 rdf:rest Neb5c675146304397a5434d96e6469cbc
207 Nfbcf4b71a1d042db9bc2c246bdd49a35 schema:name Department of Hemato-Oncology, Antoine Lacassagne Center, Nice, France
208 rdf:type schema:Organization
209 Nfcb5c03aa71d4c5588561f0fe607db02 rdf:first sg:person.0702212261.34
210 rdf:rest N540a9efc920549deafab98d2e57e90a7
211 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
212 schema:name Medical and Health Sciences
213 rdf:type schema:DefinedTerm
214 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
215 schema:name Oncology and Carcinogenesis
216 rdf:type schema:DefinedTerm
217 sg:grant.2693192 http://pending.schema.org/fundedItem sg:pub.10.1038/sj.leu.2403932
218 rdf:type schema:MonetaryGrant
219 sg:journal.1097065 schema:issn 0887-6924
220 1476-5551
221 schema:name Leukemia
222 rdf:type schema:Periodical
223 sg:person.01014211567.13 schema:affiliation https://www.grid.ac/institutes/grid.418936.1
224 schema:familyName Suciu
225 schema:givenName S
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014211567.13
227 rdf:type schema:Person
228 sg:person.010455515057.22 schema:affiliation N5003badf4d9b4464a5184bc3527983d8
229 schema:familyName Ferster
230 schema:givenName A
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010455515057.22
232 rdf:type schema:Person
233 sg:person.01057654417.64 schema:affiliation https://www.grid.ac/institutes/grid.411147.6
234 schema:familyName Rialland
235 schema:givenName X
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057654417.64
237 rdf:type schema:Person
238 sg:person.01077622701.25 schema:affiliation https://www.grid.ac/institutes/grid.413959.3
239 schema:familyName Bertrand
240 schema:givenName Y
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077622701.25
242 rdf:type schema:Person
243 sg:person.011047615427.27 schema:affiliation https://www.grid.ac/institutes/grid.8767.e
244 schema:familyName van der Werff ten Bosch
245 schema:givenName J
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011047615427.27
247 rdf:type schema:Person
248 sg:person.01155247165.08 schema:affiliation https://www.grid.ac/institutes/grid.413959.3
249 schema:familyName Philippe
250 schema:givenName N
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155247165.08
252 rdf:type schema:Person
253 sg:person.01164751365.30 schema:affiliation https://www.grid.ac/institutes/grid.413235.2
254 schema:familyName Vilmer
255 schema:givenName E
256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01164751365.30
257 rdf:type schema:Person
258 sg:person.01204466035.52 schema:affiliation N981b34e1a7bc4f0a9eb15f9c5774024d
259 schema:familyName Vandecruys
260 schema:givenName E
261 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204466035.52
262 rdf:type schema:Person
263 sg:person.01213352014.94 schema:affiliation https://www.grid.ac/institutes/grid.410569.f
264 schema:familyName Uyttebroeck
265 schema:givenName A
266 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213352014.94
267 rdf:type schema:Person
268 sg:person.01214171600.00 schema:affiliation Nfbcf4b71a1d042db9bc2c246bdd49a35
269 schema:familyName Thyss
270 schema:givenName A
271 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214171600.00
272 rdf:type schema:Person
273 sg:person.01261521622.02 schema:affiliation N48b56a2e1aab4763978891331fc56b86
274 schema:familyName Behar
275 schema:givenName C
276 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261521622.02
277 rdf:type schema:Person
278 sg:person.01336011345.47 schema:affiliation Naadc1f24f5d14eefa476f1b96c5b2664
279 schema:familyName Entz-Werle
280 schema:givenName N
281 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336011345.47
282 rdf:type schema:Person
283 sg:person.01345145264.83 schema:affiliation https://www.grid.ac/institutes/grid.413914.a
284 schema:familyName Hoyoux
285 schema:givenName C
286 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01345145264.83
287 rdf:type schema:Person
288 sg:person.015211451707.05 schema:affiliation https://www.grid.ac/institutes/grid.414362.6
289 schema:familyName Plouvier
290 schema:givenName E
291 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015211451707.05
292 rdf:type schema:Person
293 sg:person.0601705620.18 schema:affiliation https://www.grid.ac/institutes/grid.413959.3
294 schema:familyName Pages
295 schema:givenName M-P
296 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601705620.18
297 rdf:type schema:Person
298 sg:person.0632623045.51 schema:affiliation N59a0bc16b4204c92a5293e488ad6570c
299 schema:familyName Lutz
300 schema:givenName P
301 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632623045.51
302 rdf:type schema:Person
303 sg:person.0637705213.34 schema:affiliation https://www.grid.ac/institutes/grid.8767.e
304 schema:familyName Otten
305 schema:givenName J
306 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637705213.34
307 rdf:type schema:Person
308 sg:person.0653007001.30 schema:affiliation https://www.grid.ac/institutes/grid.413745.0
309 schema:familyName Margueritte
310 schema:givenName G
311 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653007001.30
312 rdf:type schema:Person
313 sg:person.0656150614.05 schema:affiliation N7f3eb24d32304ab8a33a2df4edb24459
314 schema:familyName Benoit
315 schema:givenName Y
316 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656150614.05
317 rdf:type schema:Person
318 sg:person.0702212261.34 schema:affiliation N2df1f56c0f9c44ccb1b1023a3d0e0b70
319 schema:familyName Norton
320 schema:givenName L
321 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702212261.34
322 rdf:type schema:Person
323 sg:pub.10.1007/978-3-642-72624-8_6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013324934
324 https://doi.org/10.1007/978-3-642-72624-8_6
325 rdf:type schema:CreativeWork
326 sg:pub.10.1007/s002770050148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020829719
327 https://doi.org/10.1007/s002770050148
328 rdf:type schema:CreativeWork
329 sg:pub.10.1038/sj.leu.2401832 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019434822
330 https://doi.org/10.1038/sj.leu.2401832
331 rdf:type schema:CreativeWork
332 sg:pub.10.1038/sj.leu.2402390 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001669761
333 https://doi.org/10.1038/sj.leu.2402390
334 rdf:type schema:CreativeWork
335 sg:pub.10.1038/sj.leu.2402782 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010836635
336 https://doi.org/10.1038/sj.leu.2402782
337 rdf:type schema:CreativeWork
338 sg:pub.10.1038/sj.leu.2403958 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005963124
339 https://doi.org/10.1038/sj.leu.2403958
340 rdf:type schema:CreativeWork
341 https://app.dimensions.ai/details/publication/pub.1074737871 schema:CreativeWork
342 https://app.dimensions.ai/details/publication/pub.1077372838 schema:CreativeWork
343 https://app.dimensions.ai/details/publication/pub.1077660802 schema:CreativeWork
344 https://app.dimensions.ai/details/publication/pub.1078440483 schema:CreativeWork
345 https://app.dimensions.ai/details/publication/pub.1078475282 schema:CreativeWork
346 https://app.dimensions.ai/details/publication/pub.1079589299 schema:CreativeWork
347 https://app.dimensions.ai/details/publication/pub.1080011790 schema:CreativeWork
348 https://app.dimensions.ai/details/publication/pub.1082895213 schema:CreativeWork
349 https://app.dimensions.ai/details/publication/pub.1082997511 schema:CreativeWork
350 https://app.dimensions.ai/details/publication/pub.1083319627 schema:CreativeWork
351 https://doi.org/10.1002/(sici)1096-911x(199603)26:3<173::aid-mpo5>3.0.co;2-h schema:sameAs https://app.dimensions.ai/details/publication/pub.1019116120
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1016/s0140-6736(97)09214-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020730183
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1111/j.1365-2141.1991.tb04444.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1045844708
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1182/blood-2002-03-0772 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024049275
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1200/jco.1989.7.9.1260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079333928
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1200/jco.1990.8.5.813 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078438169
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1200/jco.1991.9.4.572 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078193751
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1200/jco.1993.11.8.1448 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082762674
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1200/jco.2001.19.10.2705 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074814015
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1200/jco.2002.08.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064203108
370 rdf:type schema:CreativeWork
371 https://doi.org/10.7326/0003-4819-103-4-620 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073690404
372 rdf:type schema:CreativeWork
373 https://www.grid.ac/institutes/grid.410569.f schema:alternateName Universitaire Ziekenhuizen Leuven
374 schema:name Department of Pediatric Hemato-Oncology, UZ Gasthuisberg, Leuven, Belgique
375 rdf:type schema:Organization
376 https://www.grid.ac/institutes/grid.411147.6 schema:alternateName Centre Hospitalier Universitaire de Angers
377 schema:name Department of Pediatric Hemato-Oncology, CHRU, Angers, France
378 rdf:type schema:Organization
379 https://www.grid.ac/institutes/grid.411149.8 schema:alternateName Centre Hospitalier Universitaire de Caen
380 schema:name Department of Pediatrics, CHRU, Caen, France
381 rdf:type schema:Organization
382 https://www.grid.ac/institutes/grid.413235.2 schema:alternateName Hôpital Robert Debré
383 schema:name Department of Hemato-Immunology, Robert Debré Hospital, Paris, France
384 rdf:type schema:Organization
385 https://www.grid.ac/institutes/grid.413745.0 schema:alternateName Hôpital Arnaud De Villeneuve
386 schema:name Department of Onco-Hematology, Arnaud de Villeneuve Hospital, Montpellier, France
387 rdf:type schema:Organization
388 https://www.grid.ac/institutes/grid.413914.a schema:alternateName Centre hospitalier régional de la Citadelle
389 schema:name Department of Hematology, CHR de la Citadelle, Liège, Belgium
390 rdf:type schema:Organization
391 https://www.grid.ac/institutes/grid.413959.3 schema:alternateName Hôpital Debrousse
392 schema:name Department of Immuno-Hemato-Pediatrics, Debrousse Hospital, Lyon, France
393 rdf:type schema:Organization
394 https://www.grid.ac/institutes/grid.414362.6 schema:alternateName Hôpital Saint-Jacques
395 schema:name Department of Pediatric Hematology, Saint-Jacques Hospital, Besançon, France
396 rdf:type schema:Organization
397 https://www.grid.ac/institutes/grid.418936.1 schema:alternateName European Organisation for Research and Treatment of Cancer
398 schema:name EORTC Data Center, Brussels, Belgium
399 rdf:type schema:Organization
400 https://www.grid.ac/institutes/grid.8767.e schema:alternateName Vrije Universiteit Brussel
401 schema:name Department of Pediatrics, Academisch Ziekenhuis-VUB, Brussels, Belgium
402 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...