Analysis of the INK4a/ARF locus in non-Hodgkin’s lymphomas using two new internal microsatellite markers View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1999-05

AUTHORS

M Herranz, M Urioste, J Santos, C Rivas, B Martínez, J Benitez, J Fernández-Piqueras

ABSTRACT

Inactivation of the INK4a/ARF locus is a frequent event in non-Hodgkin's lymphomas (NHLs), which may be attributed to deletion, point mutation, and 5' CpG methylation at its promoter region. In the present study we evaluated the occurrence of deletions and genetic instability of INK4a/ARF locus in 30 paired normal and tumor samples of B cell NHLs by conducting an allelotypic analysis with two new polymorphic markers, one located at the intron 1 of p16INK4a gene and the other one placed downstream exon 1beta of p19ARF. Comparison of these results with those obtained in a previous paper using flanking markers (D9S171, D9S942, D9S958 and IFNA) allowed us to detect two new cases of microsatellite instability (L-446 and L-442), and to confirm the occurrence of LOH at the INK4a/ARF locus in one tumor (M-3770). On the contrary, this locus is not affected in three different tumors (L-421, L-272 and L-159) which exhibited LOH at some of the flanking markers. More... »

PAGES

808

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.leu.2401409

DOI

http://dx.doi.org/10.1038/sj.leu.2401409

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036372013

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10374887


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cyclin-Dependent Kinase Inhibitor p16", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Loss of Heterozygosity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymphoma, Non-Hodgkin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microsatellite Repeats", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Autonomous University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.5515.4", 
          "name": [
            "Laboratorio de Gen\u00e9tica Molecular Humana, Departamento de Biolog\u00eda, Universidad Aut\u00f3noma de Madrid, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Herranz", 
        "givenName": "M", 
        "id": "sg:person.0705265266.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705265266.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Autonomous University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.5515.4", 
          "name": [
            "Laboratorio de Gen\u00e9tica Molecular Humana, Departamento de Biolog\u00eda, Universidad Aut\u00f3noma de Madrid, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Urioste", 
        "givenName": "M", 
        "id": "sg:person.0765665046.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765665046.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Autonomous University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.5515.4", 
          "name": [
            "Laboratorio de Gen\u00e9tica Molecular Humana, Departamento de Biolog\u00eda, Universidad Aut\u00f3noma de Madrid, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Santos", 
        "givenName": "J", 
        "id": "sg:person.01323366573.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323366573.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz", 
          "id": "https://www.grid.ac/institutes/grid.419651.e", 
          "name": [
            "Departamentos de Gen\u00e9tica y Patolog\u00eda, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rivas", 
        "givenName": "C", 
        "id": "sg:person.01340511536.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340511536.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz", 
          "id": "https://www.grid.ac/institutes/grid.419651.e", 
          "name": [
            "Departamentos de Gen\u00e9tica y Patolog\u00eda, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mart\u00ednez", 
        "givenName": "B", 
        "id": "sg:person.01257705360.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257705360.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz", 
          "id": "https://www.grid.ac/institutes/grid.419651.e", 
          "name": [
            "Departamentos de Gen\u00e9tica y Patolog\u00eda, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Benitez", 
        "givenName": "J", 
        "id": "sg:person.01333446703.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333446703.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Autonomous University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.5515.4", 
          "name": [
            "Laboratorio de Gen\u00e9tica Molecular Humana, Departamento de Biolog\u00eda, Universidad Aut\u00f3noma de Madrid, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fern\u00e1ndez-Piqueras", 
        "givenName": "J", 
        "id": "sg:person.01106347624.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106347624.32"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/(sici)1096-8652(199705)55:1<1::aid-ajh1>3.0.co;2-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011109350"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm0795-686", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016345098", 
          "https://doi.org/10.1038/nm0795-686"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/10428199609054859", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020009584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/mcpr.1996.0064", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024280926"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2400555", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039379852", 
          "https://doi.org/10.1038/sj.leu.2400555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2400555", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039379852", 
          "https://doi.org/10.1038/sj.leu.2400555"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1999-05", 
    "datePublishedReg": "1999-05-01", 
    "description": "Inactivation of the INK4a/ARF locus is a frequent event in non-Hodgkin's lymphomas (NHLs), which may be attributed to deletion, point mutation, and 5' CpG methylation at its promoter region. In the present study we evaluated the occurrence of deletions and genetic instability of INK4a/ARF locus in 30 paired normal and tumor samples of B cell NHLs by conducting an allelotypic analysis with two new polymorphic markers, one located at the intron 1 of p16INK4a gene and the other one placed downstream exon 1beta of p19ARF. Comparison of these results with those obtained in a previous paper using flanking markers (D9S171, D9S942, D9S958 and IFNA) allowed us to detect two new cases of microsatellite instability (L-446 and L-442), and to confirm the occurrence of LOH at the INK4a/ARF locus in one tumor (M-3770). On the contrary, this locus is not affected in three different tumors (L-421, L-272 and L-159) which exhibited LOH at some of the flanking markers.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/sj.leu.2401409", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1097065", 
        "issn": [
          "0887-6924", 
          "1476-5551"
        ], 
        "name": "Leukemia", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "13"
      }
    ], 
    "name": "Analysis of the INK4a/ARF locus in non-Hodgkin\u2019s lymphomas using two new internal microsatellite markers", 
    "pagination": "808", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "ad433f18bf2da159e314523ba397835541dafbf5404a32d36f9a5ab6f2ecb056"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "10374887"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8704895"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.leu.2401409"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036372013"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.leu.2401409", 
      "https://app.dimensions.ai/details/publication/pub.1036372013"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T11:52", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000359_0000000359/records_29194_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/2401409"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.leu.2401409'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.leu.2401409'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.leu.2401409'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.leu.2401409'


 

This table displays all metadata directly associated to this object as RDF triples.

155 TRIPLES      21 PREDICATES      40 URIs      27 LITERALS      15 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.leu.2401409 schema:about N003118e2ae2443cf9595256d0ad54c66
2 N01d438a15db74d7c9336e0cd15282777
3 N0346f43ce9604e81ae419c5ab88d7b7e
4 Na657f5ff37744ee09902052635e3d6ac
5 Nc4f52c4862ed441cb8bdd54db9da3d55
6 Nf3f6dfec98e6465d969b444138182c08
7 anzsrc-for:06
8 anzsrc-for:0604
9 schema:author N58b73f6d8dd24256a3b3ffb127c02667
10 schema:citation sg:pub.10.1038/nm0795-686
11 sg:pub.10.1038/sj.leu.2400555
12 https://doi.org/10.1002/(sici)1096-8652(199705)55:1<1::aid-ajh1>3.0.co;2-y
13 https://doi.org/10.1006/mcpr.1996.0064
14 https://doi.org/10.3109/10428199609054859
15 schema:datePublished 1999-05
16 schema:datePublishedReg 1999-05-01
17 schema:description Inactivation of the INK4a/ARF locus is a frequent event in non-Hodgkin's lymphomas (NHLs), which may be attributed to deletion, point mutation, and 5' CpG methylation at its promoter region. In the present study we evaluated the occurrence of deletions and genetic instability of INK4a/ARF locus in 30 paired normal and tumor samples of B cell NHLs by conducting an allelotypic analysis with two new polymorphic markers, one located at the intron 1 of p16INK4a gene and the other one placed downstream exon 1beta of p19ARF. Comparison of these results with those obtained in a previous paper using flanking markers (D9S171, D9S942, D9S958 and IFNA) allowed us to detect two new cases of microsatellite instability (L-446 and L-442), and to confirm the occurrence of LOH at the INK4a/ARF locus in one tumor (M-3770). On the contrary, this locus is not affected in three different tumors (L-421, L-272 and L-159) which exhibited LOH at some of the flanking markers.
18 schema:genre research_article
19 schema:inLanguage en
20 schema:isAccessibleForFree true
21 schema:isPartOf N0cca1fa5cee54e349d4b53c94e9d0b60
22 Nd5933dd181e9427d8f1d5786c0416cd8
23 sg:journal.1097065
24 schema:name Analysis of the INK4a/ARF locus in non-Hodgkin’s lymphomas using two new internal microsatellite markers
25 schema:pagination 808
26 schema:productId N15a9201c97674ec7b50725ec47d4e6ce
27 N236fd2ea0b404bb98177d4518494c193
28 N6721d95e2ec74d8fa4f79b0349c025d1
29 Ne37f08ba8ac8475bb4c1c641a720f79f
30 Nee02fce06c564125b0c9f0841102e1ce
31 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036372013
32 https://doi.org/10.1038/sj.leu.2401409
33 schema:sdDatePublished 2019-04-11T11:52
34 schema:sdLicense https://scigraph.springernature.com/explorer/license/
35 schema:sdPublisher N6893df951e174589ae5686bc8893d64c
36 schema:url https://www.nature.com/articles/2401409
37 sgo:license sg:explorer/license/
38 sgo:sdDataset articles
39 rdf:type schema:ScholarlyArticle
40 N003118e2ae2443cf9595256d0ad54c66 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
41 schema:name Humans
42 rdf:type schema:DefinedTerm
43 N01d438a15db74d7c9336e0cd15282777 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
44 schema:name Chromosome Mapping
45 rdf:type schema:DefinedTerm
46 N0346f43ce9604e81ae419c5ab88d7b7e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
47 schema:name Microsatellite Repeats
48 rdf:type schema:DefinedTerm
49 N0cca1fa5cee54e349d4b53c94e9d0b60 schema:volumeNumber 13
50 rdf:type schema:PublicationVolume
51 N15a9201c97674ec7b50725ec47d4e6ce schema:name doi
52 schema:value 10.1038/sj.leu.2401409
53 rdf:type schema:PropertyValue
54 N236fd2ea0b404bb98177d4518494c193 schema:name nlm_unique_id
55 schema:value 8704895
56 rdf:type schema:PropertyValue
57 N3b303824be184d65a719486303843f87 rdf:first sg:person.0765665046.58
58 rdf:rest Nedd8eeb7d16b449aadd728cc9e9a9304
59 N3beffc8201414972ac258772d8424f38 rdf:first sg:person.01257705360.67
60 rdf:rest N3f4b9d5d7d94437d843dcef294c8b4b1
61 N3f4b9d5d7d94437d843dcef294c8b4b1 rdf:first sg:person.01333446703.24
62 rdf:rest N401c249e53bf47949a8b4d583bfd0a39
63 N401c249e53bf47949a8b4d583bfd0a39 rdf:first sg:person.01106347624.32
64 rdf:rest rdf:nil
65 N58b73f6d8dd24256a3b3ffb127c02667 rdf:first sg:person.0705265266.31
66 rdf:rest N3b303824be184d65a719486303843f87
67 N6721d95e2ec74d8fa4f79b0349c025d1 schema:name dimensions_id
68 schema:value pub.1036372013
69 rdf:type schema:PropertyValue
70 N6893df951e174589ae5686bc8893d64c schema:name Springer Nature - SN SciGraph project
71 rdf:type schema:Organization
72 N6fa35cd3e80547d080294ebeb86eaaa7 rdf:first sg:person.01340511536.71
73 rdf:rest N3beffc8201414972ac258772d8424f38
74 Na657f5ff37744ee09902052635e3d6ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Loss of Heterozygosity
76 rdf:type schema:DefinedTerm
77 Nc4f52c4862ed441cb8bdd54db9da3d55 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Cyclin-Dependent Kinase Inhibitor p16
79 rdf:type schema:DefinedTerm
80 Nd5933dd181e9427d8f1d5786c0416cd8 schema:issueNumber 5
81 rdf:type schema:PublicationIssue
82 Ne37f08ba8ac8475bb4c1c641a720f79f schema:name readcube_id
83 schema:value ad433f18bf2da159e314523ba397835541dafbf5404a32d36f9a5ab6f2ecb056
84 rdf:type schema:PropertyValue
85 Nedd8eeb7d16b449aadd728cc9e9a9304 rdf:first sg:person.01323366573.33
86 rdf:rest N6fa35cd3e80547d080294ebeb86eaaa7
87 Nee02fce06c564125b0c9f0841102e1ce schema:name pubmed_id
88 schema:value 10374887
89 rdf:type schema:PropertyValue
90 Nf3f6dfec98e6465d969b444138182c08 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Lymphoma, Non-Hodgkin
92 rdf:type schema:DefinedTerm
93 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
94 schema:name Biological Sciences
95 rdf:type schema:DefinedTerm
96 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
97 schema:name Genetics
98 rdf:type schema:DefinedTerm
99 sg:journal.1097065 schema:issn 0887-6924
100 1476-5551
101 schema:name Leukemia
102 rdf:type schema:Periodical
103 sg:person.01106347624.32 schema:affiliation https://www.grid.ac/institutes/grid.5515.4
104 schema:familyName Fernández-Piqueras
105 schema:givenName J
106 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106347624.32
107 rdf:type schema:Person
108 sg:person.01257705360.67 schema:affiliation https://www.grid.ac/institutes/grid.419651.e
109 schema:familyName Martínez
110 schema:givenName B
111 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257705360.67
112 rdf:type schema:Person
113 sg:person.01323366573.33 schema:affiliation https://www.grid.ac/institutes/grid.5515.4
114 schema:familyName Santos
115 schema:givenName J
116 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323366573.33
117 rdf:type schema:Person
118 sg:person.01333446703.24 schema:affiliation https://www.grid.ac/institutes/grid.419651.e
119 schema:familyName Benitez
120 schema:givenName J
121 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333446703.24
122 rdf:type schema:Person
123 sg:person.01340511536.71 schema:affiliation https://www.grid.ac/institutes/grid.419651.e
124 schema:familyName Rivas
125 schema:givenName C
126 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340511536.71
127 rdf:type schema:Person
128 sg:person.0705265266.31 schema:affiliation https://www.grid.ac/institutes/grid.5515.4
129 schema:familyName Herranz
130 schema:givenName M
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705265266.31
132 rdf:type schema:Person
133 sg:person.0765665046.58 schema:affiliation https://www.grid.ac/institutes/grid.5515.4
134 schema:familyName Urioste
135 schema:givenName M
136 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765665046.58
137 rdf:type schema:Person
138 sg:pub.10.1038/nm0795-686 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016345098
139 https://doi.org/10.1038/nm0795-686
140 rdf:type schema:CreativeWork
141 sg:pub.10.1038/sj.leu.2400555 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039379852
142 https://doi.org/10.1038/sj.leu.2400555
143 rdf:type schema:CreativeWork
144 https://doi.org/10.1002/(sici)1096-8652(199705)55:1<1::aid-ajh1>3.0.co;2-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1011109350
145 rdf:type schema:CreativeWork
146 https://doi.org/10.1006/mcpr.1996.0064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024280926
147 rdf:type schema:CreativeWork
148 https://doi.org/10.3109/10428199609054859 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020009584
149 rdf:type schema:CreativeWork
150 https://www.grid.ac/institutes/grid.419651.e schema:alternateName Hospital Universitario Fundación Jiménez Díaz
151 schema:name Departamentos de Genética y Patología, Fundación Jiménez Díaz, Madrid, Spain
152 rdf:type schema:Organization
153 https://www.grid.ac/institutes/grid.5515.4 schema:alternateName Autonomous University of Madrid
154 schema:name Laboratorio de Genética Molecular Humana, Departamento de Biología, Universidad Autónoma de Madrid, Madrid, Spain
155 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...