Community-based incidence of acute renal failure View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2007-07

AUTHORS

C-y Hsu, C E McCulloch, D Fan, J D Ordoñez, G M Chertow, A S Go

ABSTRACT

There is limited information about the true incidence of acute renal failure (ARF). Most studies could not quantify disease frequency in the general population as they are hospital-based and confounded by variations in threshold and the rate of hospitalization. Earlier studies relied on diagnostic codes to identify non-dialysis requiring ARF. These underestimated disease incidence since the codes have low sensitivity. Here we quantified the incidence of non-dialysis and dialysis-requiring ARF among members of a large integrated health care delivery system - Kaiser Permanente of Northern California. Non-dialysis requiring ARF was identified using changes in inpatient serum creatinine values. Between 1996 and 2003, the incidence of non-dialysis requiring ARF increased from 322.7 to 522.4 whereas that of dialysis-requiring ARF increased from 19.5 to 29.5 per 100,000 person-years. ARF was more common in men and among the elderly, although those aged 80 years or more were less likely to receive acute dialysis treatment. We conclude that the use of serum creatinine measurements to identify cases of non-dialysis requiring ARF resulted in much higher estimates of disease incidence compared with previous studies. Both dialysis-requiring and non-dialysis requiring ARFs are becoming more common. Our data underscore the public health importance of ARF. More... »

PAGES

208-212

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.ki.5002297

DOI

http://dx.doi.org/10.1038/sj.ki.5002297

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1025962825

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17507907


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