Global approach to cardiovascular risk in chronic kidney disease: Reality and opportunities for intervention View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-02

AUTHORS

L De Nicola, R Minutolo, P Chiodini, C Zoccali, P Castellino, C Donadio, M Strippoli, F Casino, M Giannattasio, F Petrarulo, M Virgilio, E Laraia, B R Di Iorio, V Savica, G Conte

ABSTRACT

The current implementation into nephrology clinical practice of guidelines on treatment of cardiovascular (CV) risk factors in chronic kidney disease (CKD) is unknown. We designed a cross-sectional analysis to evaluate the prevalence and treatment of eight modifiable CV risk factors in 1058 predialysis CKD patients (stage 3: n=486; stage 4: n=430, stage 5: n=142) followed for at least 1 year in 26 Italian renal clinics. The median nephrology follow-up was 37 months (range: 12-391 months). From stages 3 to 5, hypertension was the main complication (89, 87, and 87%), whereas smoking, high calcium-phosphate product and malnutrition were uncommon. The prevalence of proteinuria (25, 38, and 58%), anemia (16, 32, and 51%) and left ventricular hypertrophy (51, 55, and 64%) significantly increased, while hypercholesterolemia was less frequent in stage 5 (49%) than in stages 4 and 3 (59%). The vast majority of patients received multidrug antihypertensive therapy including inhibitors of renin-angiotensin system; conversely, diuretic treatment was consistently inadequate for both frequency and dose despite scarce implementation of low salt diet (19%). Statins were not prescribed in most hypercholesterolemics (78%), and epoietin treatment was largely overlooked in anemics (78%). The adjusted risk for having a higher number of uncontrolled risk factors rose in the presence of diabetes (odds ratio 1.29, 95% confidence interval 1.00-1.66), history of CV disease (odds ratio 1.48, 95% confidence interval 1.15-1.90) and CKD stages 4 and 5 (odds ratio 1.75, 95% confidence interval 1.37-2.22 and odds ratio 2.85, 95% confidence interval 2.01-4.04, respectively). In the tertiary care of CKD, treatment of hypertension is largely inadequate, whereas therapy of anemia and dyslipidemia is frequently omitted. The risk of not achieving therapeutic targets is higher in patients with diabetes, CV disease and more advanced CKD. More... »

PAGES

538-545

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.ki.5000085

DOI

http://dx.doi.org/10.1038/sj.ki.5000085

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046261063

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16395261


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antihypertensive Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cardiovascular Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chronic Disease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cross-Sectional Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Mellitus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypercholesterolemia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypertension", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypertrophy, Left Ventricular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Italy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Odds Ratio", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Practice Guidelines as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prevalence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proteinuria", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Severity of Illness Index", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Second University of Naples", 
          "id": "https://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Chair of Nephrology, Department of Medicine and Public-Health Research Center for Cardiovascular Disease, Second University of Napoli, Napoli, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "De Nicola", 
        "givenName": "L", 
        "id": "sg:person.01237672212.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237672212.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Second University of Naples", 
          "id": "https://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Chair of Nephrology, Department of Medicine and Public-Health Research Center for Cardiovascular Disease, Second University of Napoli, Napoli, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Minutolo", 
        "givenName": "R", 
        "id": "sg:person.0640713175.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0640713175.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Second University of Naples", 
          "id": "https://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Chair of Nephrology, Department of Medicine and Public-Health Research Center for Cardiovascular Disease, Second University of Napoli, Napoli, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chiodini", 
        "givenName": "P", 
        "id": "sg:person.0602602104.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602602104.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Nephrology, Consiglio Nazionale della Ricerca in Reggio Calabria, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zoccali", 
        "givenName": "C", 
        "id": "sg:person.01255360757.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255360757.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Catania", 
          "id": "https://www.grid.ac/institutes/grid.8158.4", 
          "name": [
            "Division of Nephrology, University of Catania, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Castellino", 
        "givenName": "P", 
        "id": "sg:person.0627453760.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627453760.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Pisa", 
          "id": "https://www.grid.ac/institutes/grid.5395.a", 
          "name": [
            "Division of Nephrology, University of Pisa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Donadio", 
        "givenName": "C", 
        "id": "sg:person.01177162511.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177162511.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Nephrology, University/Hospital Di Venere and S Rita, Bari, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Strippoli", 
        "givenName": "M", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Nephrology, Hospital, Matera, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Casino", 
        "givenName": "F", 
        "id": "sg:person.01031427250.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031427250.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Nephrology, Hospital, Putignano, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Giannattasio", 
        "givenName": "M", 
        "id": "sg:person.01251000021.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251000021.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Nephrology, University/Hospital Di Venere and S Rita, Bari, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Petrarulo", 
        "givenName": "F", 
        "id": "sg:person.0710566133.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710566133.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Nephrology, Hospital, Molfetta, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Virgilio", 
        "givenName": "M", 
        "id": "sg:person.0637706532.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637706532.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Nephrology, University/Hospital Di Venere and S Rita, Bari, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Laraia", 
        "givenName": "E", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Nephrology, Hospital, Solofra, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Di Iorio", 
        "givenName": "B R", 
        "id": "sg:person.01251067477.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251067477.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Nephrology, Hospital, Messina, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Savica", 
        "givenName": "V", 
        "id": "sg:person.01154632140.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154632140.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Second University of Naples", 
          "id": "https://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Chair of Nephrology, Department of Medicine and Public-Health Research Center for Cardiovascular Disease, Second University of Napoli, Napoli, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Conte", 
        "givenName": "G", 
        "id": "sg:person.0614417252.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614417252.41"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1161/01.hyp.0000107251.49515.c2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000003377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.hyp.0000107251.49515.c2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000003377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.hyp.0000107251.49515.c2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000003377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1523-1755.2004.00797.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001364932", 
          "https://doi.org/10.1111/j.1523-1755.2004.00797.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.ajkd.2004.01.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002679589"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.293.14.1737", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002937527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa041031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005610447"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.ajkd.2003.12.046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006710906"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000143629.55725.d9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007662814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.ajkd.2005.03.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008055684"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.hyp.0000164577.81087.70", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009529814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.hyp.0000164577.81087.70", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009529814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199808063390607", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010704386"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1523-1755.2005.00145.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011440471", 
          "https://doi.org/10.1111/j.1523-1755.2005.00145.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2004070597", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011577402"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2004070597", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011577402"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ndt/gfh771", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013794137"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0085-2538(15)50905-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014832566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0272-6386(00)70334-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015917004"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004872-200306000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016792153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004872-200306000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016792153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004872-200306000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016792153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000143892.84582.60", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021742077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mhj.2002.125513", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022813889"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0272-6386(03)00407-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025131516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0272-6386(03)00407-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025131516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2004080656", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027920224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2004080656", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027920224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2004080656", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027920224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/ajkd.2002.36861", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029496522"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/ajkd.2002.36861", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029496522"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1523-1755.2005.00227.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031243603", 
          "https://doi.org/10.1111/j.1523-1755.2005.00227.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1046/j.1523-1755.2003.00273.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032304452", 
          "https://doi.org/10.1046/j.1523-1755.2003.00273.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1523-1755.2003.00273.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032304452"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.285.19.2486", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033739611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/ajkd.2003.50018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035643867"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/ajkd.2003.50018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035643867"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000095676.90936.80", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038647312"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/ajkd.2001.26850", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039104669"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1523-1755.2004.00894.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039260545", 
          "https://doi.org/10.1111/j.1523-1755.2004.00894.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/ajkd.2001.22070", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039900375"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(86)90837-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040287180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(86)90837-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040287180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1523-1755.2004.00481.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041078589", 
          "https://doi.org/10.1111/j.1523-1755.2004.00481.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/ajkd.2002.32799", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041427834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/sim.1659", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043081286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm200006223422511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044756172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.1997.00440420033005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045882573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.164.6.659", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046965982"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1523-1755.2005.00463.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050689152", 
          "https://doi.org/10.1111/j.1523-1755.2005.00463.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1523-1755.2005.00463.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050689152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2003.08.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051762401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.157.21.2413", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054115475"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000068461.45784.2f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000068461.45784.2f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000068461.45784.2f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000123691.46138.e2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000123691.46138.e2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000123691.46138.e2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-130-6-199903160-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073703194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074839812", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074851631", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075017372", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076610301", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082954341", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083367855", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/0471249688", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1098661133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/0471249688", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1098661133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/2347760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101983279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/2347760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101983279"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2006-02", 
    "datePublishedReg": "2006-02-01", 
    "description": "The current implementation into nephrology clinical practice of guidelines on treatment of cardiovascular (CV) risk factors in chronic kidney disease (CKD) is unknown. We designed a cross-sectional analysis to evaluate the prevalence and treatment of eight modifiable CV risk factors in 1058 predialysis CKD patients (stage 3: n=486; stage 4: n=430, stage 5: n=142) followed for at least 1 year in 26 Italian renal clinics. The median nephrology follow-up was 37 months (range: 12-391 months). From stages 3 to 5, hypertension was the main complication (89, 87, and 87%), whereas smoking, high calcium-phosphate product and malnutrition were uncommon. The prevalence of proteinuria (25, 38, and 58%), anemia (16, 32, and 51%) and left ventricular hypertrophy (51, 55, and 64%) significantly increased, while hypercholesterolemia was less frequent in stage 5 (49%) than in stages 4 and 3 (59%). The vast majority of patients received multidrug antihypertensive therapy including inhibitors of renin-angiotensin system; conversely, diuretic treatment was consistently inadequate for both frequency and dose despite scarce implementation of low salt diet (19%). Statins were not prescribed in most hypercholesterolemics (78%), and epoietin treatment was largely overlooked in anemics (78%). The adjusted risk for having a higher number of uncontrolled risk factors rose in the presence of diabetes (odds ratio 1.29, 95% confidence interval 1.00-1.66), history of CV disease (odds ratio 1.48, 95% confidence interval 1.15-1.90) and CKD stages 4 and 5 (odds ratio 1.75, 95% confidence interval 1.37-2.22 and odds ratio 2.85, 95% confidence interval 2.01-4.04, respectively). In the tertiary care of CKD, treatment of hypertension is largely inadequate, whereas therapy of anemia and dyslipidemia is frequently omitted. The risk of not achieving therapeutic targets is higher in patients with diabetes, CV disease and more advanced CKD.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/sj.ki.5000085", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1015319", 
        "issn": [
          "0085-2538", 
          "1523-1755"
        ], 
        "name": "Kidney International", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "69"
      }
    ], 
    "name": "Global approach to cardiovascular risk in chronic kidney disease: Reality and opportunities for intervention", 
    "pagination": "538-545", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "dc5d967f1801420ba444bd11ce54f5db6737e90f31980c98d3d7fd48e08742c7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "16395261"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0323470"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.ki.5000085"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1046261063"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.ki.5000085", 
      "https://app.dimensions.ai/details/publication/pub.1046261063"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T22:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8690_00000426.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/ki/journal/v69/n3/full/5000085a.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.ki.5000085'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.ki.5000085'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.ki.5000085'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.ki.5000085'


 

This table displays all metadata directly associated to this object as RDF triples.

434 TRIPLES      21 PREDICATES      103 URIs      43 LITERALS      31 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.ki.5000085 schema:about N0cc0a6ccd56c42c2a493993f6b6ed582
2 N1009717963f3460c9b5196562174fdc7
3 N12fc7a6b1a9d43428221567285e71573
4 N23cbf5b953e64d269da85659132a70d1
5 N2da0b34d2acd4677aeee5d88213ccfeb
6 N300bc3f764864ec3b1a0a40711d7471a
7 N36e1704cfc484b3cbee8a79f2948a60d
8 N4777b856f2684f7282320f8bf83c6dff
9 N481ec4094b4b4508a39c1b0f8f824da7
10 N57a0bc312db04c6baac636405f3588dd
11 N58b3223ad510466d9fa3deaeffe5667c
12 N6149879dab874bd0ade1d94f4449659a
13 N69cbce765828438caf17e9b376601a13
14 N8f1f8751472543a29fd35909efe78550
15 N91030b84983b402b980039e88fb2000f
16 N983c2d66bdc54e00b3814eac7ba17be0
17 N99d08b4771cb48689b0dc6ddfb5ffdaf
18 N9d40daaaa502443aa500d7286c1bc65a
19 Nb04186fb4cca4eb6a273f63b490792e4
20 Ne1390be87f524eadbd242b738fa250cd
21 Neab18c90e776457e81d9d3bba94d68ea
22 Nfdff0e1ea00a45edacdb8d1abf35fa12
23 anzsrc-for:11
24 anzsrc-for:1103
25 schema:author N9c91dfeeaf5740ce95dedfff866d9e3e
26 schema:citation sg:pub.10.1046/j.1523-1755.2003.00273.x
27 sg:pub.10.1111/j.1523-1755.2004.00481.x
28 sg:pub.10.1111/j.1523-1755.2004.00797.x
29 sg:pub.10.1111/j.1523-1755.2004.00894.x
30 sg:pub.10.1111/j.1523-1755.2005.00145.x
31 sg:pub.10.1111/j.1523-1755.2005.00227.x
32 sg:pub.10.1111/j.1523-1755.2005.00463.x
33 https://app.dimensions.ai/details/publication/pub.1074839812
34 https://app.dimensions.ai/details/publication/pub.1074851631
35 https://app.dimensions.ai/details/publication/pub.1075017372
36 https://app.dimensions.ai/details/publication/pub.1076610301
37 https://app.dimensions.ai/details/publication/pub.1082954341
38 https://app.dimensions.ai/details/publication/pub.1083367855
39 https://doi.org/10.1001/archinte.157.21.2413
40 https://doi.org/10.1001/archinte.164.6.659
41 https://doi.org/10.1001/archinte.1997.00440420033005
42 https://doi.org/10.1001/jama.285.19.2486
43 https://doi.org/10.1001/jama.293.14.1737
44 https://doi.org/10.1002/0471249688
45 https://doi.org/10.1002/sim.1659
46 https://doi.org/10.1016/j.jacc.2003.08.001
47 https://doi.org/10.1016/s0085-2538(15)50905-8
48 https://doi.org/10.1016/s0140-6736(86)90837-8
49 https://doi.org/10.1016/s0272-6386(00)70334-9
50 https://doi.org/10.1016/s0272-6386(03)00407-4
51 https://doi.org/10.1046/j.1523-1755.2003.00273.x
52 https://doi.org/10.1053/ajkd.2001.22070
53 https://doi.org/10.1053/ajkd.2001.26850
54 https://doi.org/10.1053/ajkd.2002.32799
55 https://doi.org/10.1053/ajkd.2002.36861
56 https://doi.org/10.1053/ajkd.2003.50018
57 https://doi.org/10.1053/j.ajkd.2003.12.046
58 https://doi.org/10.1053/j.ajkd.2004.01.009
59 https://doi.org/10.1053/j.ajkd.2005.03.019
60 https://doi.org/10.1056/nejm199808063390607
61 https://doi.org/10.1056/nejm200006223422511
62 https://doi.org/10.1056/nejmoa041031
63 https://doi.org/10.1067/mhj.2002.125513
64 https://doi.org/10.1093/ndt/gfh771
65 https://doi.org/10.1097/00004872-200306000-00001
66 https://doi.org/10.1097/01.asn.0000068461.45784.2f
67 https://doi.org/10.1097/01.asn.0000123691.46138.e2
68 https://doi.org/10.1111/j.1523-1755.2005.00463.x
69 https://doi.org/10.1161/01.cir.0000095676.90936.80
70 https://doi.org/10.1161/01.cir.0000143629.55725.d9
71 https://doi.org/10.1161/01.cir.0000143892.84582.60
72 https://doi.org/10.1161/01.hyp.0000107251.49515.c2
73 https://doi.org/10.1161/01.hyp.0000164577.81087.70
74 https://doi.org/10.1681/asn.2004070597
75 https://doi.org/10.1681/asn.2004080656
76 https://doi.org/10.2307/2347760
77 https://doi.org/10.7326/0003-4819-130-6-199903160-00002
78 schema:datePublished 2006-02
79 schema:datePublishedReg 2006-02-01
80 schema:description The current implementation into nephrology clinical practice of guidelines on treatment of cardiovascular (CV) risk factors in chronic kidney disease (CKD) is unknown. We designed a cross-sectional analysis to evaluate the prevalence and treatment of eight modifiable CV risk factors in 1058 predialysis CKD patients (stage 3: n=486; stage 4: n=430, stage 5: n=142) followed for at least 1 year in 26 Italian renal clinics. The median nephrology follow-up was 37 months (range: 12-391 months). From stages 3 to 5, hypertension was the main complication (89, 87, and 87%), whereas smoking, high calcium-phosphate product and malnutrition were uncommon. The prevalence of proteinuria (25, 38, and 58%), anemia (16, 32, and 51%) and left ventricular hypertrophy (51, 55, and 64%) significantly increased, while hypercholesterolemia was less frequent in stage 5 (49%) than in stages 4 and 3 (59%). The vast majority of patients received multidrug antihypertensive therapy including inhibitors of renin-angiotensin system; conversely, diuretic treatment was consistently inadequate for both frequency and dose despite scarce implementation of low salt diet (19%). Statins were not prescribed in most hypercholesterolemics (78%), and epoietin treatment was largely overlooked in anemics (78%). The adjusted risk for having a higher number of uncontrolled risk factors rose in the presence of diabetes (odds ratio 1.29, 95% confidence interval 1.00-1.66), history of CV disease (odds ratio 1.48, 95% confidence interval 1.15-1.90) and CKD stages 4 and 5 (odds ratio 1.75, 95% confidence interval 1.37-2.22 and odds ratio 2.85, 95% confidence interval 2.01-4.04, respectively). In the tertiary care of CKD, treatment of hypertension is largely inadequate, whereas therapy of anemia and dyslipidemia is frequently omitted. The risk of not achieving therapeutic targets is higher in patients with diabetes, CV disease and more advanced CKD.
81 schema:genre research_article
82 schema:inLanguage en
83 schema:isAccessibleForFree true
84 schema:isPartOf N8e99cebc4b9442559a8fb98fa31d1930
85 Nc587143d3fad431e86f9bd1a8541b276
86 sg:journal.1015319
87 schema:name Global approach to cardiovascular risk in chronic kidney disease: Reality and opportunities for intervention
88 schema:pagination 538-545
89 schema:productId N305609b0748f4cc1848144a29ca78041
90 N552729cfe6ee46edb34974fee3042d9e
91 N7e74a48838ef474c85e94006b982850e
92 Nc635478147ab449781f76c1c0530ee71
93 Nf695392ec8fa4c868f6a199a1701a54a
94 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046261063
95 https://doi.org/10.1038/sj.ki.5000085
96 schema:sdDatePublished 2019-04-10T22:19
97 schema:sdLicense https://scigraph.springernature.com/explorer/license/
98 schema:sdPublisher N7bb6a7e6be514db694fcd835e76fd97a
99 schema:url http://www.nature.com/ki/journal/v69/n3/full/5000085a.html
100 sgo:license sg:explorer/license/
101 sgo:sdDataset articles
102 rdf:type schema:ScholarlyArticle
103 N0cc0a6ccd56c42c2a493993f6b6ed582 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Italy
105 rdf:type schema:DefinedTerm
106 N1009717963f3460c9b5196562174fdc7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Male
108 rdf:type schema:DefinedTerm
109 N11cc5ff243b8476281fcff1195b1db5e rdf:first sg:person.01255360757.86
110 rdf:rest N4f54286e077d4d03bc9219470a4d48ee
111 N12fc7a6b1a9d43428221567285e71573 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Odds Ratio
113 rdf:type schema:DefinedTerm
114 N23cbf5b953e64d269da85659132a70d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Cross-Sectional Studies
116 rdf:type schema:DefinedTerm
117 N2da0b34d2acd4677aeee5d88213ccfeb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Proteinuria
119 rdf:type schema:DefinedTerm
120 N300bc3f764864ec3b1a0a40711d7471a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Severity of Illness Index
122 rdf:type schema:DefinedTerm
123 N305609b0748f4cc1848144a29ca78041 schema:name readcube_id
124 schema:value dc5d967f1801420ba444bd11ce54f5db6737e90f31980c98d3d7fd48e08742c7
125 rdf:type schema:PropertyValue
126 N36e1704cfc484b3cbee8a79f2948a60d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Risk Factors
128 rdf:type schema:DefinedTerm
129 N3838b8f8df544c85a51d5a05fbb002de rdf:first sg:person.01177162511.97
130 rdf:rest Ndadcc613647949fc9a355599a96f74e9
131 N4777b856f2684f7282320f8bf83c6dff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Humans
133 rdf:type schema:DefinedTerm
134 N481ec4094b4b4508a39c1b0f8f824da7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Diabetes Mellitus
136 rdf:type schema:DefinedTerm
137 N4f54286e077d4d03bc9219470a4d48ee rdf:first sg:person.0627453760.30
138 rdf:rest N3838b8f8df544c85a51d5a05fbb002de
139 N507aa9b035b047228d61fc7b6939803e schema:name Division of Nephrology, Consiglio Nazionale della Ricerca in Reggio Calabria, Italy
140 rdf:type schema:Organization
141 N552729cfe6ee46edb34974fee3042d9e schema:name nlm_unique_id
142 schema:value 0323470
143 rdf:type schema:PropertyValue
144 N57a0bc312db04c6baac636405f3588dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Female
146 rdf:type schema:DefinedTerm
147 N58b3223ad510466d9fa3deaeffe5667c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Practice Guidelines as Topic
149 rdf:type schema:DefinedTerm
150 N6149879dab874bd0ade1d94f4449659a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Middle Aged
152 rdf:type schema:DefinedTerm
153 N671a799ed13441adaa785177fde9731e rdf:first sg:person.01251067477.13
154 rdf:rest N7e7c4c57d3364732867229949dc84941
155 N69cbce765828438caf17e9b376601a13 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Prevalence
157 rdf:type schema:DefinedTerm
158 N6b875cc88b0546a5a359c16dc6e88141 schema:name Division of Nephrology, Hospital, Molfetta, Italy
159 rdf:type schema:Organization
160 N74bc15c4386648d98f0765b0096e3c5e rdf:first sg:person.01251000021.32
161 rdf:rest Nd6d6c99669b5469ebee19f61dcf2974e
162 N75281edbbb924d84aa83db80e8403f97 schema:name Division of Nephrology, University/Hospital Di Venere and S Rita, Bari, Italy
163 rdf:type schema:Organization
164 N756f5ac7e4144ba89232eab6e6f53622 schema:name Division of Nephrology, University/Hospital Di Venere and S Rita, Bari, Italy
165 rdf:type schema:Organization
166 N7bb6a7e6be514db694fcd835e76fd97a schema:name Springer Nature - SN SciGraph project
167 rdf:type schema:Organization
168 N7e74a48838ef474c85e94006b982850e schema:name doi
169 schema:value 10.1038/sj.ki.5000085
170 rdf:type schema:PropertyValue
171 N7e7c4c57d3364732867229949dc84941 rdf:first sg:person.01154632140.17
172 rdf:rest Nf68d3187369740b8b328fea22c353806
173 N8e99cebc4b9442559a8fb98fa31d1930 schema:issueNumber 3
174 rdf:type schema:PublicationIssue
175 N8f1f8751472543a29fd35909efe78550 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Aged, 80 and over
177 rdf:type schema:DefinedTerm
178 N91030b84983b402b980039e88fb2000f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Kidney Diseases
180 rdf:type schema:DefinedTerm
181 N96d572dd5c244e71b0c9aca00bd7eae2 schema:name Division of Nephrology, Hospital, Solofra, Italy
182 rdf:type schema:Organization
183 N983c2d66bdc54e00b3814eac7ba17be0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
184 schema:name Chronic Disease
185 rdf:type schema:DefinedTerm
186 N99d08b4771cb48689b0dc6ddfb5ffdaf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Cardiovascular Diseases
188 rdf:type schema:DefinedTerm
189 N9c91dfeeaf5740ce95dedfff866d9e3e rdf:first sg:person.01237672212.10
190 rdf:rest Nf23a35d4925e418eba7cf35df3b049f7
191 N9d40daaaa502443aa500d7286c1bc65a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Aged
193 rdf:type schema:DefinedTerm
194 Na19bfa1e233f4b36a27a03059bd501e8 rdf:first sg:person.0602602104.71
195 rdf:rest N11cc5ff243b8476281fcff1195b1db5e
196 Na6eb7f7e52f14f2793729677acdf9755 rdf:first sg:person.0637706532.04
197 rdf:rest Ndcad9b5389194e7082201d18ecc87be3
198 Nb04186fb4cca4eb6a273f63b490792e4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Hypertrophy, Left Ventricular
200 rdf:type schema:DefinedTerm
201 Nb6426ea9ede844499e42034f6d27ac9e schema:name Division of Nephrology, University/Hospital Di Venere and S Rita, Bari, Italy
202 rdf:type schema:Organization
203 Nbcf2eb248e3942d39ecc15f550564d09 rdf:first sg:person.01031427250.86
204 rdf:rest N74bc15c4386648d98f0765b0096e3c5e
205 Nc587143d3fad431e86f9bd1a8541b276 schema:volumeNumber 69
206 rdf:type schema:PublicationVolume
207 Nc635478147ab449781f76c1c0530ee71 schema:name dimensions_id
208 schema:value pub.1046261063
209 rdf:type schema:PropertyValue
210 Nd24dc0d3e6af449f925ffe00d4a4a666 schema:affiliation N75281edbbb924d84aa83db80e8403f97
211 schema:familyName Strippoli
212 schema:givenName M
213 rdf:type schema:Person
214 Nd6d6c99669b5469ebee19f61dcf2974e rdf:first sg:person.0710566133.42
215 rdf:rest Na6eb7f7e52f14f2793729677acdf9755
216 Ndadcc613647949fc9a355599a96f74e9 rdf:first Nd24dc0d3e6af449f925ffe00d4a4a666
217 rdf:rest Nbcf2eb248e3942d39ecc15f550564d09
218 Ndcad9b5389194e7082201d18ecc87be3 rdf:first Nee1baf359d4e47fe95d6f4a247f15060
219 rdf:rest N671a799ed13441adaa785177fde9731e
220 Ne1390be87f524eadbd242b738fa250cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
221 schema:name Hypertension
222 rdf:type schema:DefinedTerm
223 Ne4c7998f9e924f6e8a9bdd6ef20c1c73 schema:name Division of Nephrology, Hospital, Messina, Italy
224 rdf:type schema:Organization
225 Neab18c90e776457e81d9d3bba94d68ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
226 schema:name Antihypertensive Agents
227 rdf:type schema:DefinedTerm
228 Nee1baf359d4e47fe95d6f4a247f15060 schema:affiliation N756f5ac7e4144ba89232eab6e6f53622
229 schema:familyName Laraia
230 schema:givenName E
231 rdf:type schema:Person
232 Nf23a35d4925e418eba7cf35df3b049f7 rdf:first sg:person.0640713175.97
233 rdf:rest Na19bfa1e233f4b36a27a03059bd501e8
234 Nf577af37ae8a436ca068c6576f178d4f schema:name Division of Nephrology, Hospital, Matera, Italy
235 rdf:type schema:Organization
236 Nf68d3187369740b8b328fea22c353806 rdf:first sg:person.0614417252.41
237 rdf:rest rdf:nil
238 Nf695392ec8fa4c868f6a199a1701a54a schema:name pubmed_id
239 schema:value 16395261
240 rdf:type schema:PropertyValue
241 Nfd6368445e7f43a98818f02ea99c5b5c schema:name Division of Nephrology, Hospital, Putignano, Italy
242 rdf:type schema:Organization
243 Nfdff0e1ea00a45edacdb8d1abf35fa12 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
244 schema:name Hypercholesterolemia
245 rdf:type schema:DefinedTerm
246 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
247 schema:name Medical and Health Sciences
248 rdf:type schema:DefinedTerm
249 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
250 schema:name Clinical Sciences
251 rdf:type schema:DefinedTerm
252 sg:journal.1015319 schema:issn 0085-2538
253 1523-1755
254 schema:name Kidney International
255 rdf:type schema:Periodical
256 sg:person.01031427250.86 schema:affiliation Nf577af37ae8a436ca068c6576f178d4f
257 schema:familyName Casino
258 schema:givenName F
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031427250.86
260 rdf:type schema:Person
261 sg:person.01154632140.17 schema:affiliation Ne4c7998f9e924f6e8a9bdd6ef20c1c73
262 schema:familyName Savica
263 schema:givenName V
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154632140.17
265 rdf:type schema:Person
266 sg:person.01177162511.97 schema:affiliation https://www.grid.ac/institutes/grid.5395.a
267 schema:familyName Donadio
268 schema:givenName C
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177162511.97
270 rdf:type schema:Person
271 sg:person.01237672212.10 schema:affiliation https://www.grid.ac/institutes/grid.9841.4
272 schema:familyName De Nicola
273 schema:givenName L
274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237672212.10
275 rdf:type schema:Person
276 sg:person.01251000021.32 schema:affiliation Nfd6368445e7f43a98818f02ea99c5b5c
277 schema:familyName Giannattasio
278 schema:givenName M
279 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251000021.32
280 rdf:type schema:Person
281 sg:person.01251067477.13 schema:affiliation N96d572dd5c244e71b0c9aca00bd7eae2
282 schema:familyName Di Iorio
283 schema:givenName B R
284 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251067477.13
285 rdf:type schema:Person
286 sg:person.01255360757.86 schema:affiliation N507aa9b035b047228d61fc7b6939803e
287 schema:familyName Zoccali
288 schema:givenName C
289 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255360757.86
290 rdf:type schema:Person
291 sg:person.0602602104.71 schema:affiliation https://www.grid.ac/institutes/grid.9841.4
292 schema:familyName Chiodini
293 schema:givenName P
294 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602602104.71
295 rdf:type schema:Person
296 sg:person.0614417252.41 schema:affiliation https://www.grid.ac/institutes/grid.9841.4
297 schema:familyName Conte
298 schema:givenName G
299 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614417252.41
300 rdf:type schema:Person
301 sg:person.0627453760.30 schema:affiliation https://www.grid.ac/institutes/grid.8158.4
302 schema:familyName Castellino
303 schema:givenName P
304 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627453760.30
305 rdf:type schema:Person
306 sg:person.0637706532.04 schema:affiliation N6b875cc88b0546a5a359c16dc6e88141
307 schema:familyName Virgilio
308 schema:givenName M
309 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637706532.04
310 rdf:type schema:Person
311 sg:person.0640713175.97 schema:affiliation https://www.grid.ac/institutes/grid.9841.4
312 schema:familyName Minutolo
313 schema:givenName R
314 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0640713175.97
315 rdf:type schema:Person
316 sg:person.0710566133.42 schema:affiliation Nb6426ea9ede844499e42034f6d27ac9e
317 schema:familyName Petrarulo
318 schema:givenName F
319 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710566133.42
320 rdf:type schema:Person
321 sg:pub.10.1046/j.1523-1755.2003.00273.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032304452
322 https://doi.org/10.1046/j.1523-1755.2003.00273.x
323 rdf:type schema:CreativeWork
324 sg:pub.10.1111/j.1523-1755.2004.00481.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1041078589
325 https://doi.org/10.1111/j.1523-1755.2004.00481.x
326 rdf:type schema:CreativeWork
327 sg:pub.10.1111/j.1523-1755.2004.00797.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001364932
328 https://doi.org/10.1111/j.1523-1755.2004.00797.x
329 rdf:type schema:CreativeWork
330 sg:pub.10.1111/j.1523-1755.2004.00894.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039260545
331 https://doi.org/10.1111/j.1523-1755.2004.00894.x
332 rdf:type schema:CreativeWork
333 sg:pub.10.1111/j.1523-1755.2005.00145.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1011440471
334 https://doi.org/10.1111/j.1523-1755.2005.00145.x
335 rdf:type schema:CreativeWork
336 sg:pub.10.1111/j.1523-1755.2005.00227.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1031243603
337 https://doi.org/10.1111/j.1523-1755.2005.00227.x
338 rdf:type schema:CreativeWork
339 sg:pub.10.1111/j.1523-1755.2005.00463.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050689152
340 https://doi.org/10.1111/j.1523-1755.2005.00463.x
341 rdf:type schema:CreativeWork
342 https://app.dimensions.ai/details/publication/pub.1074839812 schema:CreativeWork
343 https://app.dimensions.ai/details/publication/pub.1074851631 schema:CreativeWork
344 https://app.dimensions.ai/details/publication/pub.1075017372 schema:CreativeWork
345 https://app.dimensions.ai/details/publication/pub.1076610301 schema:CreativeWork
346 https://app.dimensions.ai/details/publication/pub.1082954341 schema:CreativeWork
347 https://app.dimensions.ai/details/publication/pub.1083367855 schema:CreativeWork
348 https://doi.org/10.1001/archinte.157.21.2413 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054115475
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1001/archinte.164.6.659 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046965982
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1001/archinte.1997.00440420033005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045882573
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1001/jama.285.19.2486 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033739611
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1001/jama.293.14.1737 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002937527
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1002/0471249688 schema:sameAs https://app.dimensions.ai/details/publication/pub.1098661133
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1002/sim.1659 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043081286
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1016/j.jacc.2003.08.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051762401
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1016/s0085-2538(15)50905-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014832566
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1016/s0140-6736(86)90837-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040287180
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1016/s0272-6386(00)70334-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015917004
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1016/s0272-6386(03)00407-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025131516
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1046/j.1523-1755.2003.00273.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032304452
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1053/ajkd.2001.22070 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039900375
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1053/ajkd.2001.26850 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039104669
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1053/ajkd.2002.32799 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041427834
379 rdf:type schema:CreativeWork
380 https://doi.org/10.1053/ajkd.2002.36861 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029496522
381 rdf:type schema:CreativeWork
382 https://doi.org/10.1053/ajkd.2003.50018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035643867
383 rdf:type schema:CreativeWork
384 https://doi.org/10.1053/j.ajkd.2003.12.046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006710906
385 rdf:type schema:CreativeWork
386 https://doi.org/10.1053/j.ajkd.2004.01.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002679589
387 rdf:type schema:CreativeWork
388 https://doi.org/10.1053/j.ajkd.2005.03.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008055684
389 rdf:type schema:CreativeWork
390 https://doi.org/10.1056/nejm199808063390607 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010704386
391 rdf:type schema:CreativeWork
392 https://doi.org/10.1056/nejm200006223422511 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044756172
393 rdf:type schema:CreativeWork
394 https://doi.org/10.1056/nejmoa041031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005610447
395 rdf:type schema:CreativeWork
396 https://doi.org/10.1067/mhj.2002.125513 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022813889
397 rdf:type schema:CreativeWork
398 https://doi.org/10.1093/ndt/gfh771 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013794137
399 rdf:type schema:CreativeWork
400 https://doi.org/10.1097/00004872-200306000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016792153
401 rdf:type schema:CreativeWork
402 https://doi.org/10.1097/01.asn.0000068461.45784.2f schema:sameAs https://app.dimensions.ai/details/publication/pub.1060319163
403 rdf:type schema:CreativeWork
404 https://doi.org/10.1097/01.asn.0000123691.46138.e2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060319572
405 rdf:type schema:CreativeWork
406 https://doi.org/10.1111/j.1523-1755.2005.00463.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050689152
407 rdf:type schema:CreativeWork
408 https://doi.org/10.1161/01.cir.0000095676.90936.80 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038647312
409 rdf:type schema:CreativeWork
410 https://doi.org/10.1161/01.cir.0000143629.55725.d9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007662814
411 rdf:type schema:CreativeWork
412 https://doi.org/10.1161/01.cir.0000143892.84582.60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021742077
413 rdf:type schema:CreativeWork
414 https://doi.org/10.1161/01.hyp.0000107251.49515.c2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000003377
415 rdf:type schema:CreativeWork
416 https://doi.org/10.1161/01.hyp.0000164577.81087.70 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009529814
417 rdf:type schema:CreativeWork
418 https://doi.org/10.1681/asn.2004070597 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011577402
419 rdf:type schema:CreativeWork
420 https://doi.org/10.1681/asn.2004080656 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027920224
421 rdf:type schema:CreativeWork
422 https://doi.org/10.2307/2347760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101983279
423 rdf:type schema:CreativeWork
424 https://doi.org/10.7326/0003-4819-130-6-199903160-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073703194
425 rdf:type schema:CreativeWork
426 https://www.grid.ac/institutes/grid.5395.a schema:alternateName University of Pisa
427 schema:name Division of Nephrology, University of Pisa, Italy
428 rdf:type schema:Organization
429 https://www.grid.ac/institutes/grid.8158.4 schema:alternateName University of Catania
430 schema:name Division of Nephrology, University of Catania, Italy
431 rdf:type schema:Organization
432 https://www.grid.ac/institutes/grid.9841.4 schema:alternateName Second University of Naples
433 schema:name Chair of Nephrology, Department of Medicine and Public-Health Research Center for Cardiovascular Disease, Second University of Napoli, Napoli, Italy
434 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...