Recent advances in ABE fermentation: hyper-butanol producing Clostridium beijerinckii BA101 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-11

AUTHORS

N Qureshi, HP Blaschek

ABSTRACT

This is an overview of the mutant strain Clostridium beijerinckii BA101 which produces solvents (acetone-butanol-ethanol, ABE) at elevated levels. This organism expresses high levels of amylases when grown on starch. C. beijerinckii BA101 hydrolyzes starch effectively and produces solvent in the concentration range of 27-29 g x l(-1). C. beijerinckii BA101 has been characterized for both substrate and butanol inhibition. Supplementing the fermentation medium (MP2) with sodium acetate enhances solvent production to 33 g x l(-1). The results of studies utilizing commercial fermentation medium and pilot plant-scale reactors are consistent with the results using small-scale reactors. Pervaporation, a technique to recover solvents, has been applied to fed-batch reactors containing C. beijerinckii BA101, and solvent production as high as 165 g x l(-1) has been achieved. Immobilization of C. beijerinckii BA101 by adsorption and use in a continuous reactor resulted in reactor productivity of 15.8 g x l(-1) x h(-1). Recent economic studies employing C. beijerinckii BA101 suggested that butanol can be produced at US$0.20-0.25 x lb(-1) by employing batch fermentation and distillative recovery. Application of new technologies such as pervaporation, fed-batch culture, and immobilized cell reactors is expected to further reduce these prices. More... »

PAGES

287-291

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.jim.7000114

DOI

http://dx.doi.org/10.1038/sj.jim.7000114

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013294441

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11781803


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