Effect of nifedipine on adiponectin in hypertensive patients with type 2 diabetes mellitus View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2007-01

AUTHORS

S Nomura, N Inami, Y Kimura, S Omoto, A Shouzu, M Nishikawa, T Iwasaka

ABSTRACT

Nifedipine, a dihydropyridine calcium antagonist, improves endothelial function in patients with hypercholesterolaemia by enhancing nitric oxide (NO) activity, and increases endothelial NO bioavailability by antioxidant mechanisms. We administered a long-acting nifedipine formulation (controlled release (CR) nifedipine: 20 mg/day) to hypertensive patients for 6 months. There were no other changes of drug treatment during therapy with CR nifedipine. Clinical and biochemical data obtained before and after CR nifedipine administration were compared. All markers were measured by enzyme-linked immunosorbant assay. The levels of soluble markers (soluble CD40 ligand, soluble P-selectin, and soluble E-selectin), microparticles (MP) (platelet-derived MP, monocyte-derived MP, and endothelial cell-derived MP), and adiponectin differed between the control group and the hypertension group. The levels of these markers were also different in hypertensive patients with and without type 2 diabetes compared with the control group. In the hypertensive patients with type 2 diabetes, all markers except adiponectin decreased significantly after 3 months of CR nifedipine treatment. In contrast, markers were unchanged in the hypertensive patients without type 2 diabetes. Adiponectin was increased after 6 months of CR nifedipine treatment in hypertensive patients with type 2 diabetes. The effects of CR nifedipine on platelet/monocyte activation and adiponectin levels demonstrated in the present study indicate the potential effectiveness of calcium antagonist therapy for hypertensive patients with type 2 diabetes. More... »

PAGES

1002100

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.jhh.1002100

DOI

http://dx.doi.org/10.1038/sj.jhh.1002100

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021333804

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17051237


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adiponectin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Calcium Channel Blockers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Complications", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Mellitus, Type 2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypertension", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nifedipine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Kishiwada City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415381.a", 
          "name": [
            "Division of Hematology, Kishiwada City Hospital, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nomura", 
        "givenName": "S", 
        "id": "sg:person.0637542245.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637542245.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Inami", 
        "givenName": "N", 
        "id": "sg:person.0751430045.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751430045.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kimura", 
        "givenName": "Y", 
        "id": "sg:person.0731365376.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731365376.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Omoto", 
        "givenName": "S", 
        "id": "sg:person.0625354566.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625354566.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shouzu", 
        "givenName": "A", 
        "id": "sg:person.01103473400.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103473400.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishikawa", 
        "givenName": "M", 
        "id": "sg:person.01033035076.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033035076.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iwasaka", 
        "givenName": "T", 
        "id": "sg:person.01027604020.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027604020.40"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1161/01.cir.100.25.2473", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001441312"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199901143400207", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003372113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00314918", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005960838", 
          "https://doi.org/10.1007/bf00314918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00314918", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005960838", 
          "https://doi.org/10.1007/bf00314918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0140-6736(90)91121-p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007273458"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00125-001-0772-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008035004", 
          "https://doi.org/10.1007/s00125-001-0772-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00125-001-0772-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008035004", 
          "https://doi.org/10.1007/s00125-001-0772-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1056-8727(02)00172-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008489355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1056-8727(02)00172-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008489355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(98)04311-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008729184"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0049-3848(94)90166-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010336578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.hyp.37.2.240", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011065478"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.mbc.0000176197.48134.08", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011204267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.mbc.0000176197.48134.08", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011204267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.mbc.0000176197.48134.08", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011204267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.hyp.23.2.145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013732191"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/107602960401000302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014976305"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/107602960401000302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014976305"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m307878200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017518459"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0021-9150(95)05551-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024453747"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diacare.27.7.1680", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024510564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.thromres.2005.04.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025436692"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.thromres.2005.04.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025436692"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.jhh.1001447", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026349118", 
          "https://doi.org/10.1038/sj.jhh.1001447"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.jhh.1001447", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026349118", 
          "https://doi.org/10.1038/sj.jhh.1001447"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199604113341502", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027755123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004872-198804000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029082823"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004872-198804000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029082823"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.atv.20.6.1595", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029685152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0049-3848(87)90358-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030003309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.101.3.311", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030474464"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.1999.0255", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031987283"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.hyp.37.3.943", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032673398"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.diabres.2004.10.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033446215"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00125-003-1224-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037129044", 
          "https://doi.org/10.1007/s00125-003-1224-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00125-003-1224-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037129044", 
          "https://doi.org/10.1007/s00125-003-1224-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ki.1992.309", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038018514", 
          "https://doi.org/10.1038/ki.1992.309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.atherosclerosis.2004.01.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039305568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.102.11.1296", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042251851"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02982082", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044054805", 
          "https://doi.org/10.1007/bf02982082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02982082", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044054805", 
          "https://doi.org/10.1007/bf02982082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.1994.2396", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046284853"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.82.6.1940", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047446935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2141.1980.tb08705.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048003952"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.thromres.2004.08.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048095477"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004872-199610000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051450082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00004872-199610000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051450082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.109.1.389", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051485682"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.jhh.1001863", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052480759", 
          "https://doi.org/10.1038/sj.jhh.1001863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.jhh.1001863", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052480759", 
          "https://doi.org/10.1038/sj.jhh.1001863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0008-6363(98)00341-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054580302"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2002-38248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057419276"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-199710000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060206019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-199710000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060206019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-199710000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060206019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-199908000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060206757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-199908000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060206757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-199908000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060206757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem.86.5.7463", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064324385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diabetes.47.11.1786", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070743732"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diacare.20.7.1183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070747779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079423168", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082397297", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2007-01", 
    "datePublishedReg": "2007-01-01", 
    "description": "Nifedipine, a dihydropyridine calcium antagonist, improves endothelial function in patients with hypercholesterolaemia by enhancing nitric oxide (NO) activity, and increases endothelial NO bioavailability by antioxidant mechanisms. We administered a long-acting nifedipine formulation (controlled release (CR) nifedipine: 20 mg/day) to hypertensive patients for 6 months. There were no other changes of drug treatment during therapy with CR nifedipine. Clinical and biochemical data obtained before and after CR nifedipine administration were compared. All markers were measured by enzyme-linked immunosorbant assay. The levels of soluble markers (soluble CD40 ligand, soluble P-selectin, and soluble E-selectin), microparticles (MP) (platelet-derived MP, monocyte-derived MP, and endothelial cell-derived MP), and adiponectin differed between the control group and the hypertension group. The levels of these markers were also different in hypertensive patients with and without type 2 diabetes compared with the control group. In the hypertensive patients with type 2 diabetes, all markers except adiponectin decreased significantly after 3 months of CR nifedipine treatment. In contrast, markers were unchanged in the hypertensive patients without type 2 diabetes. Adiponectin was increased after 6 months of CR nifedipine treatment in hypertensive patients with type 2 diabetes. The effects of CR nifedipine on platelet/monocyte activation and adiponectin levels demonstrated in the present study indicate the potential effectiveness of calcium antagonist therapy for hypertensive patients with type 2 diabetes.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/sj.jhh.1002100", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5800451", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1098658", 
        "issn": [
          "0950-9240", 
          "1476-5527"
        ], 
        "name": "Journal of Human Hypertension", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "21"
      }
    ], 
    "name": "Effect of nifedipine on adiponectin in hypertensive patients with type 2 diabetes mellitus", 
    "pagination": "1002100", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "65a50c5a7f75f7e40e6a3b17d1386a2f6f431c1f27d658ac96d1df078e334eb3"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "17051237"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8811625"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.jhh.1002100"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1021333804"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.jhh.1002100", 
      "https://app.dimensions.ai/details/publication/pub.1021333804"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T11:57", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000359_0000000359/records_29222_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/1002100"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.jhh.1002100'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.jhh.1002100'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.jhh.1002100'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.jhh.1002100'


 

This table displays all metadata directly associated to this object as RDF triples.

311 TRIPLES      21 PREDICATES      88 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.jhh.1002100 schema:about N0a1f05624a4c4f8a9b701ffcf38d0013
2 N17607f6f1c5448f2a72db44e414c2436
3 N2388b1f9241f4a1d915a25397762625e
4 N40b78ac7ad0043a68043d91bc99081c8
5 N86654dd65c7b4b93b51ce02a18134418
6 N86722945620b4cbb9a733a3f4f41e2f5
7 N9c33c4f2bcf0421f88e0c0f3a261b0ed
8 Nb391106e097b46e0ace122b325522a09
9 Nc0143fb1a1154f4b987bc3940a5fa438
10 Nd767c0aa4ee74dbc89bf3daae40b627c
11 Ne87f11b21aa1485b8bb41e3406faae91
12 Nee3d0d98ab6143f1bc1f8c9e808d128b
13 Nf5b32db051b74680a4f1ac4325055d94
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author N70024e86b9984da090dff8d085aa3825
17 schema:citation sg:pub.10.1007/bf00314918
18 sg:pub.10.1007/bf02982082
19 sg:pub.10.1007/s00125-001-0772-7
20 sg:pub.10.1007/s00125-003-1224-3
21 sg:pub.10.1038/ki.1992.309
22 sg:pub.10.1038/sj.jhh.1001447
23 sg:pub.10.1038/sj.jhh.1001863
24 https://app.dimensions.ai/details/publication/pub.1079423168
25 https://app.dimensions.ai/details/publication/pub.1082397297
26 https://doi.org/10.1006/bbrc.1994.2396
27 https://doi.org/10.1006/bbrc.1999.0255
28 https://doi.org/10.1016/0021-9150(95)05551-7
29 https://doi.org/10.1016/0049-3848(87)90358-6
30 https://doi.org/10.1016/0049-3848(94)90166-x
31 https://doi.org/10.1016/0140-6736(90)91121-p
32 https://doi.org/10.1016/j.atherosclerosis.2004.01.027
33 https://doi.org/10.1016/j.diabres.2004.10.010
34 https://doi.org/10.1016/j.thromres.2004.08.015
35 https://doi.org/10.1016/j.thromres.2005.04.008
36 https://doi.org/10.1016/s0008-6363(98)00341-1
37 https://doi.org/10.1016/s0140-6736(98)04311-6
38 https://doi.org/10.1016/s1056-8727(02)00172-1
39 https://doi.org/10.1055/s-2002-38248
40 https://doi.org/10.1056/nejm199604113341502
41 https://doi.org/10.1056/nejm199901143400207
42 https://doi.org/10.1074/jbc.m307878200
43 https://doi.org/10.1083/jcb.109.1.389
44 https://doi.org/10.1097/00004872-198804000-00001
45 https://doi.org/10.1097/00004872-199610000-00013
46 https://doi.org/10.1097/00005344-199710000-00005
47 https://doi.org/10.1097/00005344-199908000-00010
48 https://doi.org/10.1097/01.mbc.0000176197.48134.08
49 https://doi.org/10.1111/j.1365-2141.1980.tb08705.x
50 https://doi.org/10.1161/01.atv.20.6.1595
51 https://doi.org/10.1161/01.cir.100.25.2473
52 https://doi.org/10.1161/01.cir.101.3.311
53 https://doi.org/10.1161/01.cir.102.11.1296
54 https://doi.org/10.1161/01.cir.82.6.1940
55 https://doi.org/10.1161/01.hyp.23.2.145
56 https://doi.org/10.1161/01.hyp.37.2.240
57 https://doi.org/10.1161/01.hyp.37.3.943
58 https://doi.org/10.1177/107602960401000302
59 https://doi.org/10.1210/jcem.86.5.7463
60 https://doi.org/10.2337/diabetes.47.11.1786
61 https://doi.org/10.2337/diacare.20.7.1183
62 https://doi.org/10.2337/diacare.27.7.1680
63 schema:datePublished 2007-01
64 schema:datePublishedReg 2007-01-01
65 schema:description Nifedipine, a dihydropyridine calcium antagonist, improves endothelial function in patients with hypercholesterolaemia by enhancing nitric oxide (NO) activity, and increases endothelial NO bioavailability by antioxidant mechanisms. We administered a long-acting nifedipine formulation (controlled release (CR) nifedipine: 20 mg/day) to hypertensive patients for 6 months. There were no other changes of drug treatment during therapy with CR nifedipine. Clinical and biochemical data obtained before and after CR nifedipine administration were compared. All markers were measured by enzyme-linked immunosorbant assay. The levels of soluble markers (soluble CD40 ligand, soluble P-selectin, and soluble E-selectin), microparticles (MP) (platelet-derived MP, monocyte-derived MP, and endothelial cell-derived MP), and adiponectin differed between the control group and the hypertension group. The levels of these markers were also different in hypertensive patients with and without type 2 diabetes compared with the control group. In the hypertensive patients with type 2 diabetes, all markers except adiponectin decreased significantly after 3 months of CR nifedipine treatment. In contrast, markers were unchanged in the hypertensive patients without type 2 diabetes. Adiponectin was increased after 6 months of CR nifedipine treatment in hypertensive patients with type 2 diabetes. The effects of CR nifedipine on platelet/monocyte activation and adiponectin levels demonstrated in the present study indicate the potential effectiveness of calcium antagonist therapy for hypertensive patients with type 2 diabetes.
66 schema:genre research_article
67 schema:inLanguage en
68 schema:isAccessibleForFree true
69 schema:isPartOf N3de2c3f04ed144c5a93e9ce6070ed786
70 N76ad7e7df3b2471c93b6a82e0716ac76
71 sg:journal.1098658
72 schema:name Effect of nifedipine on adiponectin in hypertensive patients with type 2 diabetes mellitus
73 schema:pagination 1002100
74 schema:productId N58ac1b38895a4d55ac52fb8d64d610f7
75 N700554529d4f4599bbd8ed2580615d7a
76 N756846b415084a65b85287b8cdc325c0
77 Nd57fce942e564179b431187b95d01401
78 Nf150185f31f64d6ab19618d7396bdda7
79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021333804
80 https://doi.org/10.1038/sj.jhh.1002100
81 schema:sdDatePublished 2019-04-11T11:57
82 schema:sdLicense https://scigraph.springernature.com/explorer/license/
83 schema:sdPublisher N22d406ad8336420d85292f68129f1c6c
84 schema:url http://www.nature.com/articles/1002100
85 sgo:license sg:explorer/license/
86 sgo:sdDataset articles
87 rdf:type schema:ScholarlyArticle
88 N0a1f05624a4c4f8a9b701ffcf38d0013 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Adiponectin
90 rdf:type schema:DefinedTerm
91 N17607f6f1c5448f2a72db44e414c2436 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Hypertension
93 rdf:type schema:DefinedTerm
94 N22d406ad8336420d85292f68129f1c6c schema:name Springer Nature - SN SciGraph project
95 rdf:type schema:Organization
96 N2388b1f9241f4a1d915a25397762625e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Aged
98 rdf:type schema:DefinedTerm
99 N2d4a9f7602624cc2acf66e12c197d9ae rdf:first sg:person.01103473400.16
100 rdf:rest Nd32bbca7ea93429baa0107b204a90218
101 N30d1d3e17f0545a0b70556a64411e91b rdf:first sg:person.0731365376.99
102 rdf:rest Nbca20778dc8e40928bb80204953ea6ad
103 N3de2c3f04ed144c5a93e9ce6070ed786 schema:issueNumber 1
104 rdf:type schema:PublicationIssue
105 N40b78ac7ad0043a68043d91bc99081c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Diabetes Mellitus, Type 2
107 rdf:type schema:DefinedTerm
108 N58ac1b38895a4d55ac52fb8d64d610f7 schema:name pubmed_id
109 schema:value 17051237
110 rdf:type schema:PropertyValue
111 N70024e86b9984da090dff8d085aa3825 rdf:first sg:person.0637542245.62
112 rdf:rest Neb08d92c5579437cab520bd819c9079c
113 N700554529d4f4599bbd8ed2580615d7a schema:name dimensions_id
114 schema:value pub.1021333804
115 rdf:type schema:PropertyValue
116 N756846b415084a65b85287b8cdc325c0 schema:name doi
117 schema:value 10.1038/sj.jhh.1002100
118 rdf:type schema:PropertyValue
119 N76ad7e7df3b2471c93b6a82e0716ac76 schema:volumeNumber 21
120 rdf:type schema:PublicationVolume
121 N86654dd65c7b4b93b51ce02a18134418 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Diabetes Complications
123 rdf:type schema:DefinedTerm
124 N86722945620b4cbb9a733a3f4f41e2f5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Middle Aged
126 rdf:type schema:DefinedTerm
127 N9c33c4f2bcf0421f88e0c0f3a261b0ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Humans
129 rdf:type schema:DefinedTerm
130 Nb391106e097b46e0ace122b325522a09 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Female
132 rdf:type schema:DefinedTerm
133 Nb8d89f65e21044d9891d0b0b27afa13a rdf:first sg:person.01027604020.40
134 rdf:rest rdf:nil
135 Nbca20778dc8e40928bb80204953ea6ad rdf:first sg:person.0625354566.04
136 rdf:rest N2d4a9f7602624cc2acf66e12c197d9ae
137 Nc0143fb1a1154f4b987bc3940a5fa438 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Time Factors
139 rdf:type schema:DefinedTerm
140 Nd32bbca7ea93429baa0107b204a90218 rdf:first sg:person.01033035076.70
141 rdf:rest Nb8d89f65e21044d9891d0b0b27afa13a
142 Nd57fce942e564179b431187b95d01401 schema:name readcube_id
143 schema:value 65a50c5a7f75f7e40e6a3b17d1386a2f6f431c1f27d658ac96d1df078e334eb3
144 rdf:type schema:PropertyValue
145 Nd767c0aa4ee74dbc89bf3daae40b627c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Nifedipine
147 rdf:type schema:DefinedTerm
148 Ne87f11b21aa1485b8bb41e3406faae91 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Biomarkers
150 rdf:type schema:DefinedTerm
151 Neb08d92c5579437cab520bd819c9079c rdf:first sg:person.0751430045.02
152 rdf:rest N30d1d3e17f0545a0b70556a64411e91b
153 Nee3d0d98ab6143f1bc1f8c9e808d128b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Calcium Channel Blockers
155 rdf:type schema:DefinedTerm
156 Nf150185f31f64d6ab19618d7396bdda7 schema:name nlm_unique_id
157 schema:value 8811625
158 rdf:type schema:PropertyValue
159 Nf5b32db051b74680a4f1ac4325055d94 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Male
161 rdf:type schema:DefinedTerm
162 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
163 schema:name Medical and Health Sciences
164 rdf:type schema:DefinedTerm
165 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
166 schema:name Clinical Sciences
167 rdf:type schema:DefinedTerm
168 sg:grant.5800451 http://pending.schema.org/fundedItem sg:pub.10.1038/sj.jhh.1002100
169 rdf:type schema:MonetaryGrant
170 sg:journal.1098658 schema:issn 0950-9240
171 1476-5527
172 schema:name Journal of Human Hypertension
173 rdf:type schema:Periodical
174 sg:person.01027604020.40 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
175 schema:familyName Iwasaka
176 schema:givenName T
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027604020.40
178 rdf:type schema:Person
179 sg:person.01033035076.70 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
180 schema:familyName Nishikawa
181 schema:givenName M
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033035076.70
183 rdf:type schema:Person
184 sg:person.01103473400.16 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
185 schema:familyName Shouzu
186 schema:givenName A
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103473400.16
188 rdf:type schema:Person
189 sg:person.0625354566.04 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
190 schema:familyName Omoto
191 schema:givenName S
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625354566.04
193 rdf:type schema:Person
194 sg:person.0637542245.62 schema:affiliation https://www.grid.ac/institutes/grid.415381.a
195 schema:familyName Nomura
196 schema:givenName S
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637542245.62
198 rdf:type schema:Person
199 sg:person.0731365376.99 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
200 schema:familyName Kimura
201 schema:givenName Y
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731365376.99
203 rdf:type schema:Person
204 sg:person.0751430045.02 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
205 schema:familyName Inami
206 schema:givenName N
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751430045.02
208 rdf:type schema:Person
209 sg:pub.10.1007/bf00314918 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005960838
210 https://doi.org/10.1007/bf00314918
211 rdf:type schema:CreativeWork
212 sg:pub.10.1007/bf02982082 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044054805
213 https://doi.org/10.1007/bf02982082
214 rdf:type schema:CreativeWork
215 sg:pub.10.1007/s00125-001-0772-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008035004
216 https://doi.org/10.1007/s00125-001-0772-7
217 rdf:type schema:CreativeWork
218 sg:pub.10.1007/s00125-003-1224-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037129044
219 https://doi.org/10.1007/s00125-003-1224-3
220 rdf:type schema:CreativeWork
221 sg:pub.10.1038/ki.1992.309 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038018514
222 https://doi.org/10.1038/ki.1992.309
223 rdf:type schema:CreativeWork
224 sg:pub.10.1038/sj.jhh.1001447 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026349118
225 https://doi.org/10.1038/sj.jhh.1001447
226 rdf:type schema:CreativeWork
227 sg:pub.10.1038/sj.jhh.1001863 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052480759
228 https://doi.org/10.1038/sj.jhh.1001863
229 rdf:type schema:CreativeWork
230 https://app.dimensions.ai/details/publication/pub.1079423168 schema:CreativeWork
231 https://app.dimensions.ai/details/publication/pub.1082397297 schema:CreativeWork
232 https://doi.org/10.1006/bbrc.1994.2396 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046284853
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1006/bbrc.1999.0255 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031987283
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/0021-9150(95)05551-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024453747
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/0049-3848(87)90358-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030003309
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/0049-3848(94)90166-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010336578
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/0140-6736(90)91121-p schema:sameAs https://app.dimensions.ai/details/publication/pub.1007273458
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1016/j.atherosclerosis.2004.01.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039305568
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1016/j.diabres.2004.10.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033446215
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1016/j.thromres.2004.08.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048095477
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1016/j.thromres.2005.04.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025436692
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1016/s0008-6363(98)00341-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054580302
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1016/s0140-6736(98)04311-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008729184
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1016/s1056-8727(02)00172-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008489355
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1055/s-2002-38248 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057419276
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1056/nejm199604113341502 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027755123
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1056/nejm199901143400207 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003372113
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1074/jbc.m307878200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017518459
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1083/jcb.109.1.389 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051485682
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1097/00004872-198804000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029082823
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1097/00004872-199610000-00013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051450082
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1097/00005344-199710000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060206019
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1097/00005344-199908000-00010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060206757
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1097/01.mbc.0000176197.48134.08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011204267
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1111/j.1365-2141.1980.tb08705.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048003952
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1161/01.atv.20.6.1595 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029685152
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1161/01.cir.100.25.2473 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001441312
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1161/01.cir.101.3.311 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030474464
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1161/01.cir.102.11.1296 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042251851
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1161/01.cir.82.6.1940 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047446935
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1161/01.hyp.23.2.145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013732191
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1161/01.hyp.37.2.240 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011065478
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1161/01.hyp.37.3.943 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032673398
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1177/107602960401000302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014976305
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1210/jcem.86.5.7463 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064324385
299 rdf:type schema:CreativeWork
300 https://doi.org/10.2337/diabetes.47.11.1786 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070743732
301 rdf:type schema:CreativeWork
302 https://doi.org/10.2337/diacare.20.7.1183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070747779
303 rdf:type schema:CreativeWork
304 https://doi.org/10.2337/diacare.27.7.1680 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024510564
305 rdf:type schema:CreativeWork
306 https://www.grid.ac/institutes/grid.410783.9 schema:alternateName Kansai Medical University
307 schema:name Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan
308 rdf:type schema:Organization
309 https://www.grid.ac/institutes/grid.415381.a schema:alternateName Kishiwada City Hospital
310 schema:name Division of Hematology, Kishiwada City Hospital, Osaka, Japan
311 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...