Obesity and the polycystic ovary syndrome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-06-25

AUTHORS

A Gambineri, C Pelusi, V Vicennati, U Pagotto, R Pasquali

ABSTRACT

The polycystic ovary syndrome (PCOS) is a condition characterized by hyperandrogenism and chronic oligo-anovulation. However, many features of the metabolic syndrome are inconsistently present in the majority of women with PCOS. Approximately 50% of PCOS women are overweight or obese and most of them have the abdominal phenotype. Obesity may play a pathogenetic role in the development of the syndrome in susceptible individuals. In fact, insulin possesses true gonadotrophic function and an increased insulin availability at the level of ovarian tissue may favour excess androgen synthesis. Obesity, particularly the abdominal phenotype, may be partly responsible for insulin resistance and associated hyperinsulinemia in women with PCOS. Therefore, obesity-related hyperinsulinemia may play a key role in favouring hyperandrogenism in these women. Other factors such as increased estrogen production rate, increased activity of the opioid system and of the hypothalamic-pituitary-adrenal axis, decreased sex hormone binding globulin synthesis and, possibly, high dietary lipid intake, may be additional mechanisms by which obesity favours the development of hyperandrogenism in PCOS. Irrespective of the pathogenetic mechanism involved, obese PCOS women have more severe hyperandrogenism and related clinical features (such as hirsutism, menstrual abnormalities and anovulation) than normal-weight PCOS women. This picture tends to be more pronounced in obese PCOS women with the abdominal phenotype.Body weight loss is associated with beneficial effects on hormones, metabolism and clinical features. A further clinical and endocrinological improvement can also be achieved by adding insulin-sensitizing agents and/or antiandrogens to weight reduction programmes. These obviously emphasize the role of obesity in the pathophysiology of PCOS. More... »

PAGES

883-896

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.ijo.0801994

DOI

http://dx.doi.org/10.1038/sj.ijo.0801994

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036743149

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12080440


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1114", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Paediatrics and Reproductive Medicine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Androgens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Body Composition", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diet", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Estrogens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Human Growth Hormone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Insulin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Luteinizing Hormone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Obesity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polycystic Ovary Syndrome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sex Hormone-Binding Globulin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Somatomedins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "beta-Endorphin", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.6292.f", 
          "name": [
            "Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gambineri", 
        "givenName": "A", 
        "id": "sg:person.0637327577.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637327577.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.6292.f", 
          "name": [
            "Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pelusi", 
        "givenName": "C", 
        "id": "sg:person.01022401230.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022401230.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.6292.f", 
          "name": [
            "Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vicennati", 
        "givenName": "V", 
        "id": "sg:person.01114343570.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114343570.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.6292.f", 
          "name": [
            "Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pagotto", 
        "givenName": "U", 
        "id": "sg:person.01022022532.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022022532.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.6292.f", 
          "name": [
            "Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pasquali", 
        "givenName": "R", 
        "id": "sg:person.0600405520.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600405520.80"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.ijo.0801277", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014417478", 
          "https://doi.org/10.1038/sj.ijo.0801277"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03348145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024870370", 
          "https://doi.org/10.1007/bf03348145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.ijo.0801271", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008931532", 
          "https://doi.org/10.1038/sj.ijo.0801271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03350782", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050663109", 
          "https://doi.org/10.1007/bf03350782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1177/107155769500200306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090631012", 
          "https://doi.org/10.1177/107155769500200306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03350787", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047851668", 
          "https://doi.org/10.1007/bf03350787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.ijo.0801281", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028384303", 
          "https://doi.org/10.1038/sj.ijo.0801281"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2002-06-25", 
    "datePublishedReg": "2002-06-25", 
    "description": "The polycystic ovary syndrome (PCOS) is a condition characterized by hyperandrogenism and chronic oligo-anovulation. However, many features of the metabolic syndrome are inconsistently present in the majority of women with PCOS. Approximately 50% of PCOS women are overweight or obese and most of them have the abdominal phenotype. Obesity may play a pathogenetic role in the development of the syndrome in susceptible individuals. In fact, insulin possesses true gonadotrophic function and an increased insulin availability at the level of ovarian tissue may favour excess androgen synthesis. Obesity, particularly the abdominal phenotype, may be partly responsible for insulin resistance and associated hyperinsulinemia in women with PCOS. Therefore, obesity-related hyperinsulinemia may play a key role in favouring hyperandrogenism in these women. Other factors such as increased estrogen production rate, increased activity of the opioid system and of the hypothalamic-pituitary-adrenal axis, decreased sex hormone binding globulin synthesis and, possibly, high dietary lipid intake, may be additional mechanisms by which obesity favours the development of hyperandrogenism in PCOS. Irrespective of the pathogenetic mechanism involved, obese PCOS women have more severe hyperandrogenism and related clinical features (such as hirsutism, menstrual abnormalities and anovulation) than normal-weight PCOS women. This picture tends to be more pronounced in obese PCOS women with the abdominal phenotype.Body weight loss is associated with beneficial effects on hormones, metabolism and clinical features. A further clinical and endocrinological improvement can also be achieved by adding insulin-sensitizing agents and/or antiandrogens to weight reduction programmes. These obviously emphasize the role of obesity in the pathophysiology of PCOS.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/sj.ijo.0801994", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1035838", 
        "issn": [
          "0307-0565", 
          "1476-5497"
        ], 
        "name": "International Journal of Obesity", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "26"
      }
    ], 
    "keywords": [
      "polycystic ovary syndrome", 
      "obese PCOS women", 
      "PCOS women", 
      "abdominal phenotype", 
      "ovary syndrome", 
      "clinical features", 
      "pathophysiology of PCOS", 
      "high dietary lipid intake", 
      "normal-weight PCOS women", 
      "development of hyperandrogenism", 
      "role of obesity", 
      "related clinical features", 
      "dietary lipid intake", 
      "weight reduction program", 
      "body weight loss", 
      "insulin-sensitizing agents", 
      "majority of women", 
      "estrogen production rates", 
      "obesity-related hyperinsulinemia", 
      "associated hyperinsulinemia", 
      "severe hyperandrogenism", 
      "endocrinological improvement", 
      "metabolic syndrome", 
      "opioid system", 
      "insulin resistance", 
      "adrenal axis", 
      "pathogenetic role", 
      "lipid intake", 
      "sex hormones", 
      "pathogenetic mechanisms", 
      "insulin availability", 
      "androgen synthesis", 
      "hyperandrogenism", 
      "obesity", 
      "ovarian tissue", 
      "susceptible individuals", 
      "syndrome", 
      "gonadotrophic function", 
      "beneficial effects", 
      "weight loss", 
      "women", 
      "hyperinsulinemia", 
      "globulin synthesis", 
      "reduction programs", 
      "hormone", 
      "phenotype", 
      "additional mechanism", 
      "pathophysiology", 
      "insulin", 
      "intake", 
      "key role", 
      "role", 
      "tissue", 
      "metabolism", 
      "majority", 
      "agents", 
      "mechanism", 
      "individuals", 
      "levels", 
      "factors", 
      "development", 
      "activity", 
      "features", 
      "rate", 
      "loss", 
      "effect", 
      "resistance", 
      "improvement", 
      "program", 
      "axis", 
      "function", 
      "availability", 
      "synthesis", 
      "picture", 
      "conditions", 
      "fact", 
      "system", 
      "production rate"
    ], 
    "name": "Obesity and the polycystic ovary syndrome", 
    "pagination": "883-896", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1036743149"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.ijo.0801994"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "12080440"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.ijo.0801994", 
      "https://app.dimensions.ai/details/publication/pub.1036743149"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-08-04T16:54", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_348.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/sj.ijo.0801994"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.ijo.0801994'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.ijo.0801994'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.ijo.0801994'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.ijo.0801994'


 

This table displays all metadata directly associated to this object as RDF triples.

255 TRIPLES      21 PREDICATES      125 URIs      109 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.ijo.0801994 schema:about N26e4aa11c89240a6bd6276e74f62150b
2 N3b61b800defe455dac788fdd408a01cc
3 N3f49afef65c34272bf420ba9fd1fd4a2
4 N5ec6b7c0e7354c68b6a5e01d3e098a11
5 N62e442f44cd64ddc9f11e6a2d73e982c
6 N764cd28a2c474824857c03eef4d20765
7 N9f8543664bc040bf90e3c15e9808ab77
8 Nbb5bd7be84c24471b1764f7162df5158
9 Nbd600d8ec98e42699fa488cb4fad9b4e
10 Nc48d5ba2ec5a47279a74b093f0e785c2
11 Nccecffef2f414ac587b2c2ecd5382e18
12 Ned851995ff90429696714d571b84ff10
13 Nf226932dc7f74c64ae9d1be88b9b6e25
14 Nf492b5b3db2741fe9b8bd1162351a185
15 anzsrc-for:11
16 anzsrc-for:1103
17 anzsrc-for:1114
18 schema:author N40a9a58a67c84391b971000feb714567
19 schema:citation sg:pub.10.1007/bf03348145
20 sg:pub.10.1007/bf03350782
21 sg:pub.10.1007/bf03350787
22 sg:pub.10.1038/sj.ijo.0801271
23 sg:pub.10.1038/sj.ijo.0801277
24 sg:pub.10.1038/sj.ijo.0801281
25 sg:pub.10.1177/107155769500200306
26 schema:datePublished 2002-06-25
27 schema:datePublishedReg 2002-06-25
28 schema:description The polycystic ovary syndrome (PCOS) is a condition characterized by hyperandrogenism and chronic oligo-anovulation. However, many features of the metabolic syndrome are inconsistently present in the majority of women with PCOS. Approximately 50% of PCOS women are overweight or obese and most of them have the abdominal phenotype. Obesity may play a pathogenetic role in the development of the syndrome in susceptible individuals. In fact, insulin possesses true gonadotrophic function and an increased insulin availability at the level of ovarian tissue may favour excess androgen synthesis. Obesity, particularly the abdominal phenotype, may be partly responsible for insulin resistance and associated hyperinsulinemia in women with PCOS. Therefore, obesity-related hyperinsulinemia may play a key role in favouring hyperandrogenism in these women. Other factors such as increased estrogen production rate, increased activity of the opioid system and of the hypothalamic-pituitary-adrenal axis, decreased sex hormone binding globulin synthesis and, possibly, high dietary lipid intake, may be additional mechanisms by which obesity favours the development of hyperandrogenism in PCOS. Irrespective of the pathogenetic mechanism involved, obese PCOS women have more severe hyperandrogenism and related clinical features (such as hirsutism, menstrual abnormalities and anovulation) than normal-weight PCOS women. This picture tends to be more pronounced in obese PCOS women with the abdominal phenotype.Body weight loss is associated with beneficial effects on hormones, metabolism and clinical features. A further clinical and endocrinological improvement can also be achieved by adding insulin-sensitizing agents and/or antiandrogens to weight reduction programmes. These obviously emphasize the role of obesity in the pathophysiology of PCOS.
29 schema:genre article
30 schema:isAccessibleForFree false
31 schema:isPartOf Nb20a497d4494480e8b4893edc95b4a88
32 Nff0eb120d9bd4151bb66c8eba2658a62
33 sg:journal.1035838
34 schema:keywords PCOS women
35 abdominal phenotype
36 activity
37 additional mechanism
38 adrenal axis
39 agents
40 androgen synthesis
41 associated hyperinsulinemia
42 availability
43 axis
44 beneficial effects
45 body weight loss
46 clinical features
47 conditions
48 development
49 development of hyperandrogenism
50 dietary lipid intake
51 effect
52 endocrinological improvement
53 estrogen production rates
54 fact
55 factors
56 features
57 function
58 globulin synthesis
59 gonadotrophic function
60 high dietary lipid intake
61 hormone
62 hyperandrogenism
63 hyperinsulinemia
64 improvement
65 individuals
66 insulin
67 insulin availability
68 insulin resistance
69 insulin-sensitizing agents
70 intake
71 key role
72 levels
73 lipid intake
74 loss
75 majority
76 majority of women
77 mechanism
78 metabolic syndrome
79 metabolism
80 normal-weight PCOS women
81 obese PCOS women
82 obesity
83 obesity-related hyperinsulinemia
84 opioid system
85 ovarian tissue
86 ovary syndrome
87 pathogenetic mechanisms
88 pathogenetic role
89 pathophysiology
90 pathophysiology of PCOS
91 phenotype
92 picture
93 polycystic ovary syndrome
94 production rate
95 program
96 rate
97 reduction programs
98 related clinical features
99 resistance
100 role
101 role of obesity
102 severe hyperandrogenism
103 sex hormones
104 susceptible individuals
105 syndrome
106 synthesis
107 system
108 tissue
109 weight loss
110 weight reduction program
111 women
112 schema:name Obesity and the polycystic ovary syndrome
113 schema:pagination 883-896
114 schema:productId N09552ba1892c4a1e92e9636f5c0e44e4
115 Ned4bbc041c5b4163a05e662c9ff8983c
116 Nf39fa2cb6ff148ff8836a02905b355db
117 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036743149
118 https://doi.org/10.1038/sj.ijo.0801994
119 schema:sdDatePublished 2022-08-04T16:54
120 schema:sdLicense https://scigraph.springernature.com/explorer/license/
121 schema:sdPublisher Nf61d4222f48c46eeb099baaacc616dc3
122 schema:url https://doi.org/10.1038/sj.ijo.0801994
123 sgo:license sg:explorer/license/
124 sgo:sdDataset articles
125 rdf:type schema:ScholarlyArticle
126 N09552ba1892c4a1e92e9636f5c0e44e4 schema:name doi
127 schema:value 10.1038/sj.ijo.0801994
128 rdf:type schema:PropertyValue
129 N26e4aa11c89240a6bd6276e74f62150b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Body Composition
131 rdf:type schema:DefinedTerm
132 N2dcde61e37ae4c02ac839af62f409c38 rdf:first sg:person.0600405520.80
133 rdf:rest rdf:nil
134 N3b61b800defe455dac788fdd408a01cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Sex Hormone-Binding Globulin
136 rdf:type schema:DefinedTerm
137 N3f49afef65c34272bf420ba9fd1fd4a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Insulin
139 rdf:type schema:DefinedTerm
140 N40a9a58a67c84391b971000feb714567 rdf:first sg:person.0637327577.43
141 rdf:rest Nf09626c591b6489c8b8d5b595221a203
142 N5ec6b7c0e7354c68b6a5e01d3e098a11 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Somatomedins
144 rdf:type schema:DefinedTerm
145 N62e442f44cd64ddc9f11e6a2d73e982c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Humans
147 rdf:type schema:DefinedTerm
148 N764cd28a2c474824857c03eef4d20765 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name beta-Endorphin
150 rdf:type schema:DefinedTerm
151 N9f8543664bc040bf90e3c15e9808ab77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Human Growth Hormone
153 rdf:type schema:DefinedTerm
154 Nb20a497d4494480e8b4893edc95b4a88 schema:issueNumber 7
155 rdf:type schema:PublicationIssue
156 Nb84eeadcebdb492d83ccc3ee8339b7b3 rdf:first sg:person.01022022532.33
157 rdf:rest N2dcde61e37ae4c02ac839af62f409c38
158 Nbb5bd7be84c24471b1764f7162df5158 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Diet
160 rdf:type schema:DefinedTerm
161 Nbd600d8ec98e42699fa488cb4fad9b4e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Polycystic Ovary Syndrome
163 rdf:type schema:DefinedTerm
164 Nc4572c3b401e47e39a26c12f42a789d3 rdf:first sg:person.01114343570.39
165 rdf:rest Nb84eeadcebdb492d83ccc3ee8339b7b3
166 Nc48d5ba2ec5a47279a74b093f0e785c2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Androgens
168 rdf:type schema:DefinedTerm
169 Nccecffef2f414ac587b2c2ecd5382e18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Estrogens
171 rdf:type schema:DefinedTerm
172 Ned4bbc041c5b4163a05e662c9ff8983c schema:name dimensions_id
173 schema:value pub.1036743149
174 rdf:type schema:PropertyValue
175 Ned851995ff90429696714d571b84ff10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Luteinizing Hormone
177 rdf:type schema:DefinedTerm
178 Nf09626c591b6489c8b8d5b595221a203 rdf:first sg:person.01022401230.14
179 rdf:rest Nc4572c3b401e47e39a26c12f42a789d3
180 Nf226932dc7f74c64ae9d1be88b9b6e25 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Female
182 rdf:type schema:DefinedTerm
183 Nf39fa2cb6ff148ff8836a02905b355db schema:name pubmed_id
184 schema:value 12080440
185 rdf:type schema:PropertyValue
186 Nf492b5b3db2741fe9b8bd1162351a185 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Obesity
188 rdf:type schema:DefinedTerm
189 Nf61d4222f48c46eeb099baaacc616dc3 schema:name Springer Nature - SN SciGraph project
190 rdf:type schema:Organization
191 Nff0eb120d9bd4151bb66c8eba2658a62 schema:volumeNumber 26
192 rdf:type schema:PublicationVolume
193 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
194 schema:name Medical and Health Sciences
195 rdf:type schema:DefinedTerm
196 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
197 schema:name Clinical Sciences
198 rdf:type schema:DefinedTerm
199 anzsrc-for:1114 schema:inDefinedTermSet anzsrc-for:
200 schema:name Paediatrics and Reproductive Medicine
201 rdf:type schema:DefinedTerm
202 sg:journal.1035838 schema:issn 0307-0565
203 1476-5497
204 schema:name International Journal of Obesity
205 schema:publisher Springer Nature
206 rdf:type schema:Periodical
207 sg:person.01022022532.33 schema:affiliation grid-institutes:grid.6292.f
208 schema:familyName Pagotto
209 schema:givenName U
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022022532.33
211 rdf:type schema:Person
212 sg:person.01022401230.14 schema:affiliation grid-institutes:grid.6292.f
213 schema:familyName Pelusi
214 schema:givenName C
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022401230.14
216 rdf:type schema:Person
217 sg:person.01114343570.39 schema:affiliation grid-institutes:grid.6292.f
218 schema:familyName Vicennati
219 schema:givenName V
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114343570.39
221 rdf:type schema:Person
222 sg:person.0600405520.80 schema:affiliation grid-institutes:grid.6292.f
223 schema:familyName Pasquali
224 schema:givenName R
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600405520.80
226 rdf:type schema:Person
227 sg:person.0637327577.43 schema:affiliation grid-institutes:grid.6292.f
228 schema:familyName Gambineri
229 schema:givenName A
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637327577.43
231 rdf:type schema:Person
232 sg:pub.10.1007/bf03348145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024870370
233 https://doi.org/10.1007/bf03348145
234 rdf:type schema:CreativeWork
235 sg:pub.10.1007/bf03350782 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050663109
236 https://doi.org/10.1007/bf03350782
237 rdf:type schema:CreativeWork
238 sg:pub.10.1007/bf03350787 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047851668
239 https://doi.org/10.1007/bf03350787
240 rdf:type schema:CreativeWork
241 sg:pub.10.1038/sj.ijo.0801271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008931532
242 https://doi.org/10.1038/sj.ijo.0801271
243 rdf:type schema:CreativeWork
244 sg:pub.10.1038/sj.ijo.0801277 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014417478
245 https://doi.org/10.1038/sj.ijo.0801277
246 rdf:type schema:CreativeWork
247 sg:pub.10.1038/sj.ijo.0801281 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028384303
248 https://doi.org/10.1038/sj.ijo.0801281
249 rdf:type schema:CreativeWork
250 sg:pub.10.1177/107155769500200306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090631012
251 https://doi.org/10.1177/107155769500200306
252 rdf:type schema:CreativeWork
253 grid-institutes:grid.6292.f schema:alternateName Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy
254 schema:name Department of Internal Medicine, Endocrinology Unit, S. Orsola-Malpighi Hospital, University Alma Mater Studiorum, Bologna, Italy
255 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...