JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Mammalian", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Crosses, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred C57BL", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred DBA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quantitative Trait, Heritable", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thymus Gland", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hsu", 
        "givenName": "H-C", 
        "id": "sg:person.01263522210.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263522210.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Veterans Administration Medical Center, Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.280808.a", 
          "name": [
            "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA", 
            "Veterans Administration Medical Center, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "H-G", 
        "id": "sg:person.01054374560.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054374560.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Li", 
        "givenName": "L", 
        "id": "sg:person.01062167667.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062167667.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biostatistics, Section of Statistical Genetics, The University of Alabama at Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Biostatistics, Section of Statistical Genetics, The University of Alabama at Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yi", 
        "givenName": "N", 
        "id": "sg:person.01161530212.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01161530212.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yang", 
        "givenName": "P-A", 
        "id": "sg:person.016612437322.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016612437322.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wu", 
        "givenName": "Q", 
        "id": "sg:person.0660620434.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660620434.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhou", 
        "givenName": "J", 
        "id": "sg:person.01350702033.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350702033.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sun", 
        "givenName": "S", 
        "id": "sg:person.01157406035.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157406035.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Xu", 
        "givenName": "X", 
        "id": "sg:person.0675314653.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675314653.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yang", 
        "givenName": "X", 
        "id": "sg:person.01144072204.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01144072204.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Neuroscience and Department of Anatomy and Neurobiology, University of Tennessee, Memphis, TN, USA", 
          "id": "http://www.grid.ac/institutes/grid.411461.7", 
          "name": [
            "Center for Neuroscience and Department of Anatomy and Neurobiology, University of Tennessee, Memphis, TN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lu", 
        "givenName": "L", 
        "id": "sg:person.016526076440.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016526076440.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Hematology/Oncology, The Markey Cancer Center, The University of Kentucky Medical Center, Lexington, KY, USA", 
          "id": "http://www.grid.ac/institutes/grid.461341.5", 
          "name": [
            "Division of Hematology/Oncology, The Markey Cancer Center, The University of Kentucky Medical Center, Lexington, KY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Van Zant", 
        "givenName": "G", 
        "id": "sg:person.01014133010.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014133010.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Neuroscience and Department of Anatomy and Neurobiology, University of Tennessee, Memphis, TN, USA", 
          "id": "http://www.grid.ac/institutes/grid.411461.7", 
          "name": [
            "Center for Neuroscience and Department of Anatomy and Neurobiology, University of Tennessee, Memphis, TN, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Williams", 
        "givenName": "R W", 
        "id": "sg:person.01267345517.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267345517.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biostatistics, Section of Statistical Genetics, The University of Alabama at Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.265892.2", 
          "name": [
            "Department of Biostatistics, Section of Statistical Genetics, The University of Alabama at Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Allison", 
        "givenName": "D B", 
        "id": "sg:person.01014372050.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014372050.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Veterans Administration Medical Center, Birmingham, AL, USA", 
          "id": "http://www.grid.ac/institutes/grid.280808.a", 
          "name": [
            "Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA", 
            "Veterans Administration Medical Center, Birmingham, AL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mountz", 
        "givenName": "J D", 
        "id": "sg:person.07550405624.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07550405624.18"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s003359901069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049211880", 
          "https://doi.org/10.1007/s003359901069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00357089", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001004545", 
          "https://doi.org/10.1007/bf00357089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gene.6363801", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001708555", 
          "https://doi.org/10.1038/sj.gene.6363801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s003359900048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017975893", 
          "https://doi.org/10.1007/s003359900048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/gb-2001-2-11-research0046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023146795", 
          "https://doi.org/10.1186/gb-2001-2-11-research0046"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02359892", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012715330", 
          "https://doi.org/10.1007/bf02359892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/217370a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015747707", 
          "https://doi.org/10.1038/217370a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s003359900998", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002768641", 
          "https://doi.org/10.1007/s003359900998"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1006611518223", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032158393", 
          "https://doi.org/10.1023/a:1006611518223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nri842", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033977779", 
          "https://doi.org/10.1038/nri842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gene.6363667", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052270513", 
          "https://doi.org/10.1038/sj.gene.6363667"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s003359900997", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032641914", 
          "https://doi.org/10.1007/s003359900997"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00335-001-1016-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032730610", 
          "https://doi.org/10.1007/s00335-001-1016-3"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2003-08-27", 
    "datePublishedReg": "2003-08-27", 
    "description": "A comprehensive analysis of initial thymus size and involution rate has not been quantitated for different genetic backgrounds of mice, thus genetic linkage analysis of thymic involution has not been possible. Here, we have used a mathematical method to analyze the age-related decline in thymocyte count in C57BL/6 and DBA/2 mice and have observed that thymic involution could be best fit with a negative exponential curve N(t)=\u03b20 \u00d7 exp(\u2212\u03b21t), where t represents the age (day). This regression model was applied to C57BL/6 \u00d7 DBA/2 (B \u00d7 D) recombinant inbred strains of mice to identify the genetic loci influencing age-related thymic involution. There was a dramatic genetic effect of B and D alleles on thymocyte count at young age and the age-related thymic involution rate. The strongest quantitative trait loci (QTL) influencing the rate of thymic involution were mapped to mouse chromosome (Chr) 9 (D9Mit20 at 62\u2009cM) and Chr 10 (D10Mit61 at 32\u2009cM). The strongest QTLs influencing the initial thymocyte count were mapped to ChrX (DXMit324 at 26.5\u2009cM) and Chr 3 (D3Mit127 at 70.3\u2009cM). The present study suggests that the initial thymus size and the rate of thymic involution may be influenced by a relatively small number of genetic loci.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/sj.gene.6363982", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2446743", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2425848", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2466175", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1022914", 
        "issn": [
          "1466-4879", 
          "1476-5470"
        ], 
        "name": "Genes & Immunity", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "4"
      }
    ], 
    "keywords": [
      "age-related thymic involution", 
      "thymic involution", 
      "thymocyte counts", 
      "thymus size", 
      "involution rate", 
      "strains of mice", 
      "age-related decline", 
      "DBA/2 mice", 
      "younger age", 
      "mice", 
      "chromosome 9", 
      "regression models", 
      "present study", 
      "count", 
      "age", 
      "genetic loci", 
      "different genetic backgrounds", 
      "genetic background", 
      "involution", 
      "C57BL/6", 
      "DBA/2", 
      "rate", 
      "genetic linkage analysis", 
      "Chr 10", 
      "DBA/2J", 
      "Chr 3", 
      "small number", 
      "genetic effects", 
      "mouse map", 
      "linkage analysis", 
      "alleles", 
      "exponential curve", 
      "ChrX", 
      "decline", 
      "strong quantitative trait locus", 
      "study", 
      "background", 
      "effect", 
      "analysis", 
      "loci", 
      "strains", 
      "comprehensive analysis", 
      "mouse chromosome 9", 
      "number", 
      "size", 
      "curves", 
      "quantitative trait loci", 
      "method", 
      "model", 
      "trait loci", 
      "negative exponential curve", 
      "maps", 
      "mathematical methods", 
      "initial thymus size", 
      "dramatic genetic effect", 
      "age-related thymic involution rate", 
      "thymic involution rate", 
      "initial thymocyte count"
    ], 
    "name": "Age-related thymic involution in C57BL/6J \u00d7 DBA/2J recombinant-inbred mice maps to mouse chromosomes 9 and 10", 
    "pagination": "402-410", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1044906208"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.gene.6363982"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "12944977"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.gene.6363982", 
      "https://app.dimensions.ai/details/publication/pub.1044906208"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:13", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_377.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/sj.gene.6363982"
  }
]

Download the RDF metadata as:  json-ld nt turtle xml License info

This table displays all metadata directly associated to this object as RDF triples.

336 TRIPLES      22 PREDICATES      109 URIs      88 LITERALS      19 BLANK NODES