p75NTR and the concept of cellular dependence: seeing how the other half die View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1998-05

AUTHORS

Andrea Tasinato, Dale E Bredesen, James JL Wang, Nuria Assa-Munt, Sabina Sperandio, Shahrooz Rabizadeh, Xin Ye

ABSTRACT

Cells depend on specific stimuli, such as trophic factors, for survival and in the absence of such stimuli, undergo apoptosis. How do cells initiate apoptosis in response to the withdrawal of trophic factors or other dependent stimuli? Recent studies of apoptosis induction by neurotrophin withdrawal argue for a novel form of pro-apoptotic signal transduction - 'negative signal transduction' - in which the absence of ligand-receptor interaction induces cell death. We have found that the prototype for this form of signaling - the common neurotrophin receptor, p75NTR - creates a state of cellular dependence (or addiction) on neurotrophins, and that this effect requires an 'addiction/dependence domain' (ADD) in the intracytoplasmic region of p75NTR. We have recently found other receptors that include dependence domains, arguing that dependence receptors, and their associated dependence domains, may be involved in a rather general mechanism to create cellular states of dependence on trophic factors, cytokines, adhesion, electrical activity and other dependent stimuli. More... »

PAGES

365

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.cdd.4400378

DOI

http://dx.doi.org/10.1038/sj.cdd.4400378

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048995669

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10200485


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Apoptosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cytoplasm", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ligands", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nerve Growth Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neurons", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptor Protein-Tyrosine Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptor, Ciliary Neurotrophic Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptor, Nerve Growth Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptors, Nerve Growth Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Signal Transduction", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Sanford Burnham Prebys Medical Discovery Institute", 
          "id": "https://www.grid.ac/institutes/grid.479509.6", 
          "name": [
            "Program on Aging, The Burnham Institute, La Jolla, California 92037, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tasinato", 
        "givenName": "Andrea", 
        "id": "sg:person.01203425332.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203425332.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, San Diego", 
          "id": "https://www.grid.ac/institutes/grid.266100.3", 
          "name": [
            "Program on Aging, The Burnham Institute, La Jolla, California 92037, USA", 
            "Neuroscience Department, University of California, San Diego, California 92093, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bredesen", 
        "givenName": "Dale E", 
        "id": "sg:person.0642520111.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642520111.96"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California Los Angeles", 
          "id": "https://www.grid.ac/institutes/grid.19006.3e", 
          "name": [
            "Interdepartmental Program in Neuroscience, University of California, Los Angeles, California 90024, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wang", 
        "givenName": "James JL", 
        "id": "sg:person.01260376601.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260376601.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sanford Burnham Prebys Medical Discovery Institute", 
          "id": "https://www.grid.ac/institutes/grid.479509.6", 
          "name": [
            "Structural Biology Program, The Burnham Institute, La Jolla, California 92037, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Assa-Munt", 
        "givenName": "Nuria", 
        "id": "sg:person.01043726325.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043726325.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sanford Burnham Prebys Medical Discovery Institute", 
          "id": "https://www.grid.ac/institutes/grid.479509.6", 
          "name": [
            "Program on Aging, The Burnham Institute, La Jolla, California 92037, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sperandio", 
        "givenName": "Sabina", 
        "id": "sg:person.0625243510.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625243510.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California Los Angeles", 
          "id": "https://www.grid.ac/institutes/grid.19006.3e", 
          "name": [
            "Program on Aging, The Burnham Institute, La Jolla, California 92037, USA", 
            "Interdepartmental Program in Neuroscience, University of California, Los Angeles, California 90024, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rabizadeh", 
        "givenName": "Shahrooz", 
        "id": "sg:person.01073040032.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073040032.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sanford Burnham Prebys Medical Discovery Institute", 
          "id": "https://www.grid.ac/institutes/grid.479509.6", 
          "name": [
            "Program on Aging, The Burnham Institute, La Jolla, California 92037, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ye", 
        "givenName": "Xin", 
        "id": "sg:person.015201473607.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015201473607.35"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1998-05", 
    "datePublishedReg": "1998-05-01", 
    "description": "Cells depend on specific stimuli, such as trophic factors, for survival and in the absence of such stimuli, undergo apoptosis. How do cells initiate apoptosis in response to the withdrawal of trophic factors or other dependent stimuli? Recent studies of apoptosis induction by neurotrophin withdrawal argue for a novel form of pro-apoptotic signal transduction - 'negative signal transduction' - in which the absence of ligand-receptor interaction induces cell death. We have found that the prototype for this form of signaling - the common neurotrophin receptor, p75NTR - creates a state of cellular dependence (or addiction) on neurotrophins, and that this effect requires an 'addiction/dependence domain' (ADD) in the intracytoplasmic region of p75NTR. We have recently found other receptors that include dependence domains, arguing that dependence receptors, and their associated dependence domains, may be involved in a rather general mechanism to create cellular states of dependence on trophic factors, cytokines, adhesion, electrical activity and other dependent stimuli.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/sj.cdd.4400378", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1112551", 
        "issn": [
          "1350-9047", 
          "1476-5403"
        ], 
        "name": "Cell Death & Differentiation", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "5"
      }
    ], 
    "name": "p75NTR and the concept of cellular dependence: seeing how the other half die", 
    "pagination": "365", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "e968610f27cd763e8033de1c3d5592d400704735bde313d79a9c52f835a2c986"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "10200485"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9437445"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.cdd.4400378"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1048995669"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.cdd.4400378", 
      "https://app.dimensions.ai/details/publication/pub.1048995669"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:04", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000360_0000000360/records_118318_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/4400378"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400378'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400378'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400378'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400378'


 

This table displays all metadata directly associated to this object as RDF triples.

168 TRIPLES      20 PREDICATES      41 URIs      33 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.cdd.4400378 schema:about N0ade414c229c4f4f9957d52e6b2c8344
2 N0e1db73c6c104bc49b72e17707250f08
3 N22a40d9d480f4055874cfcd0517cd0fa
4 N54181485701249e7a0883e20ac27a77a
5 N5480a27254b846148ccdc116e0862aec
6 N6dd00ae52a2d4c589f07f7576a357739
7 N8617843814f448f7a25373ba56a8f3a3
8 N9f5980b35d984cf1b953afb5bda73869
9 Na381061df11846af84cfd17ca447f142
10 Nb2014ca65ef642b199afaf0abce51d4b
11 Nd2e14c8a745a416391d751e7661e9b7a
12 Nf5193e9e2d1b4b9ab3797aea2db7c20b
13 anzsrc-for:06
14 anzsrc-for:0601
15 schema:author N4a2e3edff6a04102b9d5a35cc001e709
16 schema:datePublished 1998-05
17 schema:datePublishedReg 1998-05-01
18 schema:description Cells depend on specific stimuli, such as trophic factors, for survival and in the absence of such stimuli, undergo apoptosis. How do cells initiate apoptosis in response to the withdrawal of trophic factors or other dependent stimuli? Recent studies of apoptosis induction by neurotrophin withdrawal argue for a novel form of pro-apoptotic signal transduction - 'negative signal transduction' - in which the absence of ligand-receptor interaction induces cell death. We have found that the prototype for this form of signaling - the common neurotrophin receptor, p75NTR - creates a state of cellular dependence (or addiction) on neurotrophins, and that this effect requires an 'addiction/dependence domain' (ADD) in the intracytoplasmic region of p75NTR. We have recently found other receptors that include dependence domains, arguing that dependence receptors, and their associated dependence domains, may be involved in a rather general mechanism to create cellular states of dependence on trophic factors, cytokines, adhesion, electrical activity and other dependent stimuli.
19 schema:genre research_article
20 schema:inLanguage en
21 schema:isAccessibleForFree true
22 schema:isPartOf N3fea6b5137bb47d78655225c1834dbd0
23 N8c4870eacb0249039d13186484a34bac
24 sg:journal.1112551
25 schema:name p75NTR and the concept of cellular dependence: seeing how the other half die
26 schema:pagination 365
27 schema:productId N028ba6439ea04bb9803b4abe13675bad
28 N56a96737e2824f37b28d4ada6033f646
29 N8806dbd260aa4e90acf4e63b411badbd
30 Ne16657110d0841ab911716ad55443d54
31 Nf591a0c701504f8889bdbc39d7e1ef46
32 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048995669
33 https://doi.org/10.1038/sj.cdd.4400378
34 schema:sdDatePublished 2019-04-11T12:04
35 schema:sdLicense https://scigraph.springernature.com/explorer/license/
36 schema:sdPublisher Na933b263361644c39bd01e4894322162
37 schema:url https://www.nature.com/articles/4400378
38 sgo:license sg:explorer/license/
39 sgo:sdDataset articles
40 rdf:type schema:ScholarlyArticle
41 N028ba6439ea04bb9803b4abe13675bad schema:name pubmed_id
42 schema:value 10200485
43 rdf:type schema:PropertyValue
44 N03b147b5b50a4aada3299ac36ad8ede8 rdf:first sg:person.01043726325.71
45 rdf:rest N21668fa2969a44cf9de1209b46652941
46 N0ade414c229c4f4f9957d52e6b2c8344 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
47 schema:name Receptor, Nerve Growth Factor
48 rdf:type schema:DefinedTerm
49 N0ddea8f5233a4fddb038bcab7f40ca85 rdf:first sg:person.0642520111.96
50 rdf:rest N70d06449aaa1479eb18f7f5cd28fedfa
51 N0e1db73c6c104bc49b72e17707250f08 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
52 schema:name Signal Transduction
53 rdf:type schema:DefinedTerm
54 N21668fa2969a44cf9de1209b46652941 rdf:first sg:person.0625243510.40
55 rdf:rest N610a1740992a40a0ab25325083712772
56 N22a40d9d480f4055874cfcd0517cd0fa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
57 schema:name Animals
58 rdf:type schema:DefinedTerm
59 N3fea6b5137bb47d78655225c1834dbd0 schema:issueNumber 5
60 rdf:type schema:PublicationIssue
61 N4a2e3edff6a04102b9d5a35cc001e709 rdf:first sg:person.01203425332.68
62 rdf:rest N0ddea8f5233a4fddb038bcab7f40ca85
63 N54181485701249e7a0883e20ac27a77a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
64 schema:name Cytoplasm
65 rdf:type schema:DefinedTerm
66 N5480a27254b846148ccdc116e0862aec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Neurons
68 rdf:type schema:DefinedTerm
69 N56a96737e2824f37b28d4ada6033f646 schema:name readcube_id
70 schema:value e968610f27cd763e8033de1c3d5592d400704735bde313d79a9c52f835a2c986
71 rdf:type schema:PropertyValue
72 N610a1740992a40a0ab25325083712772 rdf:first sg:person.01073040032.76
73 rdf:rest Nc57cddf8dfe74fa7bc512e9ca958f60a
74 N6dd00ae52a2d4c589f07f7576a357739 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Apoptosis
76 rdf:type schema:DefinedTerm
77 N70d06449aaa1479eb18f7f5cd28fedfa rdf:first sg:person.01260376601.09
78 rdf:rest N03b147b5b50a4aada3299ac36ad8ede8
79 N8617843814f448f7a25373ba56a8f3a3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Receptor Protein-Tyrosine Kinases
81 rdf:type schema:DefinedTerm
82 N8806dbd260aa4e90acf4e63b411badbd schema:name nlm_unique_id
83 schema:value 9437445
84 rdf:type schema:PropertyValue
85 N8c4870eacb0249039d13186484a34bac schema:volumeNumber 5
86 rdf:type schema:PublicationVolume
87 N9f5980b35d984cf1b953afb5bda73869 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Receptor, Ciliary Neurotrophic Factor
89 rdf:type schema:DefinedTerm
90 Na381061df11846af84cfd17ca447f142 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Nerve Growth Factors
92 rdf:type schema:DefinedTerm
93 Na933b263361644c39bd01e4894322162 schema:name Springer Nature - SN SciGraph project
94 rdf:type schema:Organization
95 Nb2014ca65ef642b199afaf0abce51d4b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Receptors, Nerve Growth Factor
97 rdf:type schema:DefinedTerm
98 Nc57cddf8dfe74fa7bc512e9ca958f60a rdf:first sg:person.015201473607.35
99 rdf:rest rdf:nil
100 Nd2e14c8a745a416391d751e7661e9b7a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Cell Line
102 rdf:type schema:DefinedTerm
103 Ne16657110d0841ab911716ad55443d54 schema:name dimensions_id
104 schema:value pub.1048995669
105 rdf:type schema:PropertyValue
106 Nf5193e9e2d1b4b9ab3797aea2db7c20b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Ligands
108 rdf:type schema:DefinedTerm
109 Nf591a0c701504f8889bdbc39d7e1ef46 schema:name doi
110 schema:value 10.1038/sj.cdd.4400378
111 rdf:type schema:PropertyValue
112 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
113 schema:name Biological Sciences
114 rdf:type schema:DefinedTerm
115 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
116 schema:name Biochemistry and Cell Biology
117 rdf:type schema:DefinedTerm
118 sg:journal.1112551 schema:issn 1350-9047
119 1476-5403
120 schema:name Cell Death & Differentiation
121 rdf:type schema:Periodical
122 sg:person.01043726325.71 schema:affiliation https://www.grid.ac/institutes/grid.479509.6
123 schema:familyName Assa-Munt
124 schema:givenName Nuria
125 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043726325.71
126 rdf:type schema:Person
127 sg:person.01073040032.76 schema:affiliation https://www.grid.ac/institutes/grid.19006.3e
128 schema:familyName Rabizadeh
129 schema:givenName Shahrooz
130 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073040032.76
131 rdf:type schema:Person
132 sg:person.01203425332.68 schema:affiliation https://www.grid.ac/institutes/grid.479509.6
133 schema:familyName Tasinato
134 schema:givenName Andrea
135 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203425332.68
136 rdf:type schema:Person
137 sg:person.01260376601.09 schema:affiliation https://www.grid.ac/institutes/grid.19006.3e
138 schema:familyName Wang
139 schema:givenName James JL
140 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260376601.09
141 rdf:type schema:Person
142 sg:person.015201473607.35 schema:affiliation https://www.grid.ac/institutes/grid.479509.6
143 schema:familyName Ye
144 schema:givenName Xin
145 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015201473607.35
146 rdf:type schema:Person
147 sg:person.0625243510.40 schema:affiliation https://www.grid.ac/institutes/grid.479509.6
148 schema:familyName Sperandio
149 schema:givenName Sabina
150 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625243510.40
151 rdf:type schema:Person
152 sg:person.0642520111.96 schema:affiliation https://www.grid.ac/institutes/grid.266100.3
153 schema:familyName Bredesen
154 schema:givenName Dale E
155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642520111.96
156 rdf:type schema:Person
157 https://www.grid.ac/institutes/grid.19006.3e schema:alternateName University of California Los Angeles
158 schema:name Interdepartmental Program in Neuroscience, University of California, Los Angeles, California 90024, USA
159 Program on Aging, The Burnham Institute, La Jolla, California 92037, USA
160 rdf:type schema:Organization
161 https://www.grid.ac/institutes/grid.266100.3 schema:alternateName University of California, San Diego
162 schema:name Neuroscience Department, University of California, San Diego, California 92093, USA
163 Program on Aging, The Burnham Institute, La Jolla, California 92037, USA
164 rdf:type schema:Organization
165 https://www.grid.ac/institutes/grid.479509.6 schema:alternateName Sanford Burnham Prebys Medical Discovery Institute
166 schema:name Program on Aging, The Burnham Institute, La Jolla, California 92037, USA
167 Structural Biology Program, The Burnham Institute, La Jolla, California 92037, USA
168 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...