Invasive pneumococcal disease in adult hematopoietic stem cell transplant recipients: a decade of prospective population-based surveillance View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-04

AUTHORS

D Kumar, A Humar, A Plevneshi, D Siegal, N Franke, K Green, A McGeer

ABSTRACT

Prospective population-based surveillance to assess the epidemiology of invasive pneumococcal disease (IPD) in hematopoietic stem cell transplant (HSCT) patients is limited and a comparison to the general population is lacking. By using a population-based Invasive Bacterial Diseases Network surveillance program, we studied the incidence, clinical significance, serotypes and antimicrobial resistance of IPD in a large cohort of adult HSCT patients and the general population. Streptococcus pneumoniae isolates and patient data were collected prospectively from 1995 to 2004. We identified 14 cases of IPD (based on sterile site isolates) in our HSCT population over a 10-year period. This translated to an incidence rate of 347 infections per 100 000 persons per year. This compared to an incidence of 11.5 per 100 000 persons per year in the general population (regression ratio=30.2; 95% confidence interval (CI) 17.8-50.8, P<0.00001). If nonsterile site isolates (respiratory tract) were included, the incidence rate in transplant patients was 446 per 100 000 persons per year. Serotypes 23F and 6B were most common; 100 and 69.2% of isolates were a serotype included in the pneumococcal polysaccharide and conjugate vaccines, respectively. The antimicrobial resistance rates were high, especially for trimethoprim/sulfamethoxazole. HSCT recipients are at significantly greater risk for IPD than the general population. Preventative strategies are necessary. More... »

PAGES

743

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bmt.1705964

DOI

http://dx.doi.org/10.1038/sj.bmt.1705964

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016294318

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18176614


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacteremia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hematopoietic Stem Cell Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Incidence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ontario", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pneumonia, Pneumococcal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sentinel Surveillance", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Streptococcus pneumoniae", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Alberta", 
          "id": "https://www.grid.ac/institutes/grid.17089.37", 
          "name": [
            "Division of Infectious Diseases, University of Alberta, Edmonton, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kumar", 
        "givenName": "D", 
        "id": "sg:person.0632013444.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632013444.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Alberta", 
          "id": "https://www.grid.ac/institutes/grid.17089.37", 
          "name": [
            "Division of Infectious Diseases, University of Alberta, Edmonton, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Humar", 
        "givenName": "A", 
        "id": "sg:person.012426436344.93", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012426436344.93"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mount Sinai Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416166.2", 
          "name": [
            "Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Plevneshi", 
        "givenName": "A", 
        "id": "sg:person.01273063162.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273063162.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Queen's University", 
          "id": "https://www.grid.ac/institutes/grid.410356.5", 
          "name": [
            "Department of Medicine, Queen's University, Kingston, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Siegal", 
        "givenName": "D", 
        "id": "sg:person.01372200027.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372200027.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Department of Hematology, University of Toronto, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Franke", 
        "givenName": "N", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mount Sinai Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416166.2", 
          "name": [
            "Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Green", 
        "givenName": "K", 
        "id": "sg:person.0660044362.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660044362.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mount Sinai Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416166.2", 
          "name": [
            "Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McGeer", 
        "givenName": "A", 
        "id": "sg:person.01046247262.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046247262.67"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.bmt.1704870", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002428952", 
          "https://doi.org/10.1038/sj.bmt.1704870"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.1997.03540380062032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008441346"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005792-200007000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015741375"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005792-200007000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015741375"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1702647", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017388998", 
          "https://doi.org/10.1038/sj.bmt.1702647"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-6143.2006.01705.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020737015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2141.2002.03457.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040866337"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/313716", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046962136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1034/j.1600-0609.2003.00158.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048845966"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/md.0b013e31803eb176", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052825035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/md.0b013e31803eb176", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052825035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.277.14.1148", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054160809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/377534", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058670614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074650613", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-04", 
    "datePublishedReg": "2008-04-01", 
    "description": "Prospective population-based surveillance to assess the epidemiology of invasive pneumococcal disease (IPD) in hematopoietic stem cell transplant (HSCT) patients is limited and a comparison to the general population is lacking. By using a population-based Invasive Bacterial Diseases Network surveillance program, we studied the incidence, clinical significance, serotypes and antimicrobial resistance of IPD in a large cohort of adult HSCT patients and the general population. Streptococcus pneumoniae isolates and patient data were collected prospectively from 1995 to 2004. We identified 14 cases of IPD (based on sterile site isolates) in our HSCT population over a 10-year period. This translated to an incidence rate of 347 infections per 100 000 persons per year. This compared to an incidence of 11.5 per 100 000 persons per year in the general population (regression ratio=30.2; 95% confidence interval (CI) 17.8-50.8, P<0.00001). If nonsterile site isolates (respiratory tract) were included, the incidence rate in transplant patients was 446 per 100 000 persons per year. Serotypes 23F and 6B were most common; 100 and 69.2% of isolates were a serotype included in the pneumococcal polysaccharide and conjugate vaccines, respectively. The antimicrobial resistance rates were high, especially for trimethoprim/sulfamethoxazole. HSCT recipients are at significantly greater risk for IPD than the general population. Preventative strategies are necessary.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/sj.bmt.1705964", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1096890", 
        "issn": [
          "0268-3369", 
          "1476-5365"
        ], 
        "name": "Bone Marrow Transplantation", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "8", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "41"
      }
    ], 
    "name": "Invasive pneumococcal disease in adult hematopoietic stem cell transplant recipients: a decade of prospective population-based surveillance", 
    "pagination": "743", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "4da39f2d9f8e847f893e948146d05b1b988b53972cae90963ef4ebd4bb5d0e2c"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18176614"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8702459"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.bmt.1705964"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1016294318"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.bmt.1705964", 
      "https://app.dimensions.ai/details/publication/pub.1016294318"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T21:24", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8687_00000424.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/1705964"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.bmt.1705964'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.bmt.1705964'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.bmt.1705964'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.bmt.1705964'


 

This table displays all metadata directly associated to this object as RDF triples.

208 TRIPLES      21 PREDICATES      54 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.bmt.1705964 schema:about N14af95e9b4d54cd2aea9dc958a95d8af
2 N48821e586346495cb8171f184fbb4454
3 N4ae4c2e578154435b399b81f9929344a
4 N56be575cf4774b33918184b5fa8381d1
5 N594dfa3d989e4c04b458c620fe66d39f
6 N5ba911c0d2094ce68433cc635a8b51a1
7 N64558cd0e62f482ca085556c0cc57531
8 N7224bd095aeb449aafe4ebd0fa175ef5
9 N8cb7f74ed77c40f684659173cf282f79
10 Na3db81dad03a4c748c3122c058d48270
11 Nc36863b39a254beaadab8ec52aba1604
12 Nc677bc4dc58b47fab216153b839d8784
13 Neabae8fd8dae430293f46d40757d00db
14 anzsrc-for:11
15 anzsrc-for:1117
16 schema:author N837135bdc35e4a8e869b6472cb0e68c0
17 schema:citation sg:pub.10.1038/sj.bmt.1702647
18 sg:pub.10.1038/sj.bmt.1704870
19 https://app.dimensions.ai/details/publication/pub.1074650613
20 https://doi.org/10.1001/jama.1997.03540380062032
21 https://doi.org/10.1001/jama.277.14.1148
22 https://doi.org/10.1034/j.1600-0609.2003.00158.x
23 https://doi.org/10.1046/j.1365-2141.2002.03457.x
24 https://doi.org/10.1086/313716
25 https://doi.org/10.1086/377534
26 https://doi.org/10.1097/00005792-200007000-00002
27 https://doi.org/10.1097/md.0b013e31803eb176
28 https://doi.org/10.1111/j.1600-6143.2006.01705.x
29 schema:datePublished 2008-04
30 schema:datePublishedReg 2008-04-01
31 schema:description Prospective population-based surveillance to assess the epidemiology of invasive pneumococcal disease (IPD) in hematopoietic stem cell transplant (HSCT) patients is limited and a comparison to the general population is lacking. By using a population-based Invasive Bacterial Diseases Network surveillance program, we studied the incidence, clinical significance, serotypes and antimicrobial resistance of IPD in a large cohort of adult HSCT patients and the general population. Streptococcus pneumoniae isolates and patient data were collected prospectively from 1995 to 2004. We identified 14 cases of IPD (based on sterile site isolates) in our HSCT population over a 10-year period. This translated to an incidence rate of 347 infections per 100 000 persons per year. This compared to an incidence of 11.5 per 100 000 persons per year in the general population (regression ratio=30.2; 95% confidence interval (CI) 17.8-50.8, P<0.00001). If nonsterile site isolates (respiratory tract) were included, the incidence rate in transplant patients was 446 per 100 000 persons per year. Serotypes 23F and 6B were most common; 100 and 69.2% of isolates were a serotype included in the pneumococcal polysaccharide and conjugate vaccines, respectively. The antimicrobial resistance rates were high, especially for trimethoprim/sulfamethoxazole. HSCT recipients are at significantly greater risk for IPD than the general population. Preventative strategies are necessary.
32 schema:genre research_article
33 schema:inLanguage en
34 schema:isAccessibleForFree true
35 schema:isPartOf Nb1f93b3c5f444d74b2dd2394c7de6eb5
36 Nb3bd4e02c7fa48ebaf2baaf7bf614d42
37 sg:journal.1096890
38 schema:name Invasive pneumococcal disease in adult hematopoietic stem cell transplant recipients: a decade of prospective population-based surveillance
39 schema:pagination 743
40 schema:productId N0625b28f03b545dfac4c4f74215bda72
41 N0c68de8751364b19a8a493837fa3bac3
42 N3ec2a9f7c6c4413e88455bf3e87ffe3e
43 N6ada4fec71324d9695072b3f37a3752f
44 Nb4af487bedca48fa892eababf2ddf777
45 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016294318
46 https://doi.org/10.1038/sj.bmt.1705964
47 schema:sdDatePublished 2019-04-10T21:24
48 schema:sdLicense https://scigraph.springernature.com/explorer/license/
49 schema:sdPublisher Ne88f3c2b8f6a4b268665e4ca9ae07046
50 schema:url https://www.nature.com/articles/1705964
51 sgo:license sg:explorer/license/
52 sgo:sdDataset articles
53 rdf:type schema:ScholarlyArticle
54 N00a0615115384a1d888dd511c2d9bbf6 rdf:first Na4d2e18b65fc45488f814956497238f1
55 rdf:rest Nae012991691b481a86e2f1ce7477a95a
56 N0625b28f03b545dfac4c4f74215bda72 schema:name pubmed_id
57 schema:value 18176614
58 rdf:type schema:PropertyValue
59 N0c68de8751364b19a8a493837fa3bac3 schema:name dimensions_id
60 schema:value pub.1016294318
61 rdf:type schema:PropertyValue
62 N14af95e9b4d54cd2aea9dc958a95d8af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
63 schema:name Male
64 rdf:type schema:DefinedTerm
65 N20285cc807734385800f05714df673bb rdf:first sg:person.012426436344.93
66 rdf:rest N523d0aab7f87454b8445fd3545692f57
67 N3ec2a9f7c6c4413e88455bf3e87ffe3e schema:name doi
68 schema:value 10.1038/sj.bmt.1705964
69 rdf:type schema:PropertyValue
70 N48821e586346495cb8171f184fbb4454 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Adult
72 rdf:type schema:DefinedTerm
73 N49db71a73b4744a8a422714d7c49caa0 rdf:first sg:person.01372200027.35
74 rdf:rest N00a0615115384a1d888dd511c2d9bbf6
75 N4ae4c2e578154435b399b81f9929344a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Middle Aged
77 rdf:type schema:DefinedTerm
78 N523d0aab7f87454b8445fd3545692f57 rdf:first sg:person.01273063162.33
79 rdf:rest N49db71a73b4744a8a422714d7c49caa0
80 N56be575cf4774b33918184b5fa8381d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Sentinel Surveillance
82 rdf:type schema:DefinedTerm
83 N594dfa3d989e4c04b458c620fe66d39f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Female
85 rdf:type schema:DefinedTerm
86 N5ba911c0d2094ce68433cc635a8b51a1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Humans
88 rdf:type schema:DefinedTerm
89 N64558cd0e62f482ca085556c0cc57531 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Bacteremia
91 rdf:type schema:DefinedTerm
92 N6ada4fec71324d9695072b3f37a3752f schema:name readcube_id
93 schema:value 4da39f2d9f8e847f893e948146d05b1b988b53972cae90963ef4ebd4bb5d0e2c
94 rdf:type schema:PropertyValue
95 N7224bd095aeb449aafe4ebd0fa175ef5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Hematopoietic Stem Cell Transplantation
97 rdf:type schema:DefinedTerm
98 N837135bdc35e4a8e869b6472cb0e68c0 rdf:first sg:person.0632013444.01
99 rdf:rest N20285cc807734385800f05714df673bb
100 N8cb7f74ed77c40f684659173cf282f79 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Streptococcus pneumoniae
102 rdf:type schema:DefinedTerm
103 N959124b36dcb4bf6a45ed79230dc47e3 rdf:first sg:person.01046247262.67
104 rdf:rest rdf:nil
105 Na3db81dad03a4c748c3122c058d48270 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Incidence
107 rdf:type schema:DefinedTerm
108 Na4d2e18b65fc45488f814956497238f1 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
109 schema:familyName Franke
110 schema:givenName N
111 rdf:type schema:Person
112 Nae012991691b481a86e2f1ce7477a95a rdf:first sg:person.0660044362.10
113 rdf:rest N959124b36dcb4bf6a45ed79230dc47e3
114 Nb1f93b3c5f444d74b2dd2394c7de6eb5 schema:issueNumber 8
115 rdf:type schema:PublicationIssue
116 Nb3bd4e02c7fa48ebaf2baaf7bf614d42 schema:volumeNumber 41
117 rdf:type schema:PublicationVolume
118 Nb4af487bedca48fa892eababf2ddf777 schema:name nlm_unique_id
119 schema:value 8702459
120 rdf:type schema:PropertyValue
121 Nc36863b39a254beaadab8ec52aba1604 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Ontario
123 rdf:type schema:DefinedTerm
124 Nc677bc4dc58b47fab216153b839d8784 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Prospective Studies
126 rdf:type schema:DefinedTerm
127 Ne88f3c2b8f6a4b268665e4ca9ae07046 schema:name Springer Nature - SN SciGraph project
128 rdf:type schema:Organization
129 Neabae8fd8dae430293f46d40757d00db schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Pneumonia, Pneumococcal
131 rdf:type schema:DefinedTerm
132 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
133 schema:name Medical and Health Sciences
134 rdf:type schema:DefinedTerm
135 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
136 schema:name Public Health and Health Services
137 rdf:type schema:DefinedTerm
138 sg:journal.1096890 schema:issn 0268-3369
139 1476-5365
140 schema:name Bone Marrow Transplantation
141 rdf:type schema:Periodical
142 sg:person.01046247262.67 schema:affiliation https://www.grid.ac/institutes/grid.416166.2
143 schema:familyName McGeer
144 schema:givenName A
145 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046247262.67
146 rdf:type schema:Person
147 sg:person.012426436344.93 schema:affiliation https://www.grid.ac/institutes/grid.17089.37
148 schema:familyName Humar
149 schema:givenName A
150 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012426436344.93
151 rdf:type schema:Person
152 sg:person.01273063162.33 schema:affiliation https://www.grid.ac/institutes/grid.416166.2
153 schema:familyName Plevneshi
154 schema:givenName A
155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273063162.33
156 rdf:type schema:Person
157 sg:person.01372200027.35 schema:affiliation https://www.grid.ac/institutes/grid.410356.5
158 schema:familyName Siegal
159 schema:givenName D
160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372200027.35
161 rdf:type schema:Person
162 sg:person.0632013444.01 schema:affiliation https://www.grid.ac/institutes/grid.17089.37
163 schema:familyName Kumar
164 schema:givenName D
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632013444.01
166 rdf:type schema:Person
167 sg:person.0660044362.10 schema:affiliation https://www.grid.ac/institutes/grid.416166.2
168 schema:familyName Green
169 schema:givenName K
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660044362.10
171 rdf:type schema:Person
172 sg:pub.10.1038/sj.bmt.1702647 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017388998
173 https://doi.org/10.1038/sj.bmt.1702647
174 rdf:type schema:CreativeWork
175 sg:pub.10.1038/sj.bmt.1704870 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002428952
176 https://doi.org/10.1038/sj.bmt.1704870
177 rdf:type schema:CreativeWork
178 https://app.dimensions.ai/details/publication/pub.1074650613 schema:CreativeWork
179 https://doi.org/10.1001/jama.1997.03540380062032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008441346
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1001/jama.277.14.1148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054160809
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1034/j.1600-0609.2003.00158.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048845966
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1046/j.1365-2141.2002.03457.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040866337
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1086/313716 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046962136
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1086/377534 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058670614
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1097/00005792-200007000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015741375
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1097/md.0b013e31803eb176 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052825035
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1111/j.1600-6143.2006.01705.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020737015
196 rdf:type schema:CreativeWork
197 https://www.grid.ac/institutes/grid.17063.33 schema:alternateName University of Toronto
198 schema:name Department of Hematology, University of Toronto, Toronto, Ontario, Canada
199 rdf:type schema:Organization
200 https://www.grid.ac/institutes/grid.17089.37 schema:alternateName University of Alberta
201 schema:name Division of Infectious Diseases, University of Alberta, Edmonton, Alberta, Canada
202 rdf:type schema:Organization
203 https://www.grid.ac/institutes/grid.410356.5 schema:alternateName Queen's University
204 schema:name Department of Medicine, Queen's University, Kingston, Ontario, Canada
205 rdf:type schema:Organization
206 https://www.grid.ac/institutes/grid.416166.2 schema:alternateName Mount Sinai Hospital
207 schema:name Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada
208 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...