Acute renal failure due to adenovirus-associated obstructive uropathy and necrotizing tubulointerstitial nephritis in a bone marrow transplant recipient View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2003-06-10

AUTHORS

K Mori, T Yoshihara, Y Nishimura, M Uchida, K Katsura, Y Kawase, I Hatano, H Ishida, T Chiyonobu, Y Kasubuchi, A Morimoto, T Teramura, S Imashuku

ABSTRACT

Summary:Management of post-transplant complications caused by severe adenoviral infection remains a major therapeutic challenge. A 17-year-old male who had undergone bone marrow transplantation for the treatment of acute lymphoblastic leukemia developed complete anuria following hemorrhagic cystitis 34 days after the transplant procedure. The computed tomogram scan revealed bilateral hydronephrosis, indicating acute renal failure because of obstructive uropathy. The emergency procedure of percutaneous nephrostomy caused massive bleeding in the left kidney, which eventually required a nephrectomy. Adenovirus-positive severe necrotizing tubulointerstitial nephritis was the histopathological diagnosis. Post-transplant acute renal failure because of hydronephrosis, which could be complicated by adenovirus-induced renal parenchymal disease, is of great concern and may cause significant problems with interventional treatment. More... »

PAGES

1173-1176

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bmt.1704077

DOI

http://dx.doi.org/10.1038/sj.bmt.1704077

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009510934

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12796799


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