Regression of an unresectable pancreatic tumor following nonmyeloablative allogeneic peripheral-blood stem-cell transplantation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2003-05-01

AUTHORS

Y Omuro, G Matsumoto, T Sasaki, Y Tanaka, Y Maeda, H Sakamaki, K Hiruma, K Tsuruta, T Takahashi

ABSTRACT

Summary:A 59-year-old female with an unresectable, large pancreatic tumor (10.0 × 8.0 cm2 on CT scan) underwent nonmyeloablative allogeneic peripheral-blood stem-cell transplantation from her HLA-identical sibling. Pronounced tumor regression and relief from pain without acute graft-versus-host disease (GVHD) were observed following transplantation. The patient is surviving (more than 300 days) after transplantation, with extensive chronic GVHD, and has tumor regression with an 80% reduction in tumor size. The observed clinical course may suggest a graft-versus-tumor effect on the pancreatic tumor following allogeneic stem-cell transplantation. More... »

PAGES

943-945

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bmt.1703932

DOI

http://dx.doi.org/10.1038/sj.bmt.1703932

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033382350

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12748675


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