A case of severe B cell deficiency after allogeneic stem cell transplantation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2002-09

AUTHORS

T Takahashi, S Chiba, T Matsumura, H Hirai

ABSTRACT

Insufficient immunological reconstitution is one of the serious complications of allogeneic stem cell transplantation (SCT). We report a case of severely impaired B-lymphopoiesis after allogeneic SCT for CML. The patient's bone marrow and blood cells display complete chimerism and he is currently free from leukemia. His serum immunoglobulin levels are below detection level, and B cells are absent at 2 years post transplant in both the bone marrow and blood. Other populations appear to be normal. To the best of our knowledge, this is the first report of B-lymphopoiesis being undetectable more than 2 years after allogeneic SCT. More... »

PAGES

397

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bmt.1703642

DOI

http://dx.doi.org/10.1038/sj.bmt.1703642

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008700138

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12235525


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