Predictive factors for long-term engraftment of autologous blood stem cells View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2000-12

AUTHORS

PR Duggan, D Guo, J Luider, I Auer, J Klassen, A Chaudhry, D Morris, S Glück, CB Brown, JA Russell, DA Stewart

ABSTRACT

Data from 170 consecutive patients aged 19-66 years (median age 46 years) who underwent unmanipulated autologous blood stem cell transplant (ASCT) were analyzed to determine if total CD34+ cells/kg infused, CD34+ subsets (CD34+41+, CD34+90+, CD34+33-, CD34+38-, CD34+38-DR-), peripheral blood CD34+ cell (PBCD34+) count on first apheresis day, or various clinical factors were associated with low blood counts 6 months post ASCT. Thirty-four patients were excluded from analysis either because of death (n = 17) or re-induction chemotherapy prior to 6 months post ASCT (n = 13), or because of lack of follow-up data (n = 4). Of the remaining 136 patients, 46% had low WBC ( < 4 x 10(9)/l), 41% low platelets (<150 x 10(9)/l), and 34% low hemoglobin ( < 120 g/l) at a median of 6 months following ASCT. By Spearman's rank correlation, both the total CD34+ cell dose/kg and the PBCD34+ count correlated with 6 month blood counts better than any subset of CD34+ cells or any clinical factor. The PBCD34+ count was overall a stronger predictor of 6 month blood counts than was the total CD34+ cells/kg infused. Both factors retained their significance in multivariate analysis, controlling for clinical factors. In conclusion, subsets of CD34+ cells and clinical factors are inferior to the total CD34+ cell dose/kg and PBCD34+ count in predicting 6 month blood counts following ASCT. More... »

PAGES

1299

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bmt.1702708

DOI

http://dx.doi.org/10.1038/sj.bmt.1702708

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033218958

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11223969


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens, CD34", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Cell Count", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Transfusion, Autologous", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Graft Survival", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hematopoietic Stem Cell Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunophenotyping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Predictive Value of Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Statistics, Nonparametric", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation, Autologous", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Medicine, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Duggan", 
        "givenName": "PR", 
        "id": "sg:person.01203325067.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203325067.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Epidemiology, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guo", 
        "givenName": "D", 
        "id": "sg:person.01335500110.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335500110.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Flow Cytometry, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Luider", 
        "givenName": "J", 
        "id": "sg:person.01262500314.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262500314.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Flow Cytometry, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Auer", 
        "givenName": "I", 
        "id": "sg:person.01110664210.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110664210.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Apheresis, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Klassen", 
        "givenName": "J", 
        "id": "sg:person.0642105445.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642105445.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Medicine, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chaudhry", 
        "givenName": "A", 
        "id": "sg:person.0602537007.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602537007.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Medicine, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Morris", 
        "givenName": "D", 
        "id": "sg:person.010322301312.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010322301312.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Medicine, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gl\u00fcck", 
        "givenName": "S", 
        "id": "sg:person.01021516770.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021516770.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Medicine, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Brown", 
        "givenName": "CB", 
        "id": "sg:person.013025421422.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013025421422.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Medicine, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Russell", 
        "givenName": "JA", 
        "id": "sg:person.016436141052.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016436141052.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Calgary", 
          "id": "https://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Medicine, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stewart", 
        "givenName": "DA", 
        "id": "sg:person.010012722342.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010012722342.01"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/2023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007795844", 
          "https://doi.org/10.1038/2023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/2023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007795844", 
          "https://doi.org/10.1038/2023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2141.1998.01066.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008014842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1700671", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009413018", 
          "https://doi.org/10.1038/sj.bmt.1700671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1700671", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009413018", 
          "https://doi.org/10.1038/sj.bmt.1700671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1701536", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012603980", 
          "https://doi.org/10.1038/sj.bmt.1701536"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1701536", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012603980", 
          "https://doi.org/10.1038/sj.bmt.1701536"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1537-2995.1998.38498257378.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021546267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0609.1989.tb01203.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026595034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1701923", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030376103", 
          "https://doi.org/10.1038/sj.bmt.1701923"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1701923", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030376103", 
          "https://doi.org/10.1038/sj.bmt.1701923"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1702066", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032914551", 
          "https://doi.org/10.1038/sj.bmt.1702066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1702066", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032914551", 
          "https://doi.org/10.1038/sj.bmt.1702066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci113658", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036807911"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1701886", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043233916", 
          "https://doi.org/10.1038/sj.bmt.1701886"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1701886", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043233916", 
          "https://doi.org/10.1038/sj.bmt.1701886"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1701800", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043720114", 
          "https://doi.org/10.1038/sj.bmt.1701800"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1701800", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043720114", 
          "https://doi.org/10.1038/sj.bmt.1701800"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/152581699320090", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059213504"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074475442", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1999.17.10.3128", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074528549"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075303764", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077312306", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077336840", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079470070", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082399515", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082421977", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082467296", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082504032", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082854040", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082926477", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1997.15.3.1218", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083057241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083249356", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083263798", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1998.16.6.2093", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083277776"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2000-12", 
    "datePublishedReg": "2000-12-01", 
    "description": "Data from 170 consecutive patients aged 19-66 years (median age 46 years) who underwent unmanipulated autologous blood stem cell transplant (ASCT) were analyzed to determine if total CD34+ cells/kg infused, CD34+ subsets (CD34+41+, CD34+90+, CD34+33-, CD34+38-, CD34+38-DR-), peripheral blood CD34+ cell (PBCD34+) count on first apheresis day, or various clinical factors were associated with low blood counts 6 months post ASCT. Thirty-four patients were excluded from analysis either because of death (n = 17) or re-induction chemotherapy prior to 6 months post ASCT (n = 13), or because of lack of follow-up data (n = 4). Of the remaining 136 patients, 46% had low WBC ( < 4 x 10(9)/l), 41% low platelets (<150 x 10(9)/l), and 34% low hemoglobin ( < 120 g/l) at a median of 6 months following ASCT. By Spearman's rank correlation, both the total CD34+ cell dose/kg and the PBCD34+ count correlated with 6 month blood counts better than any subset of CD34+ cells or any clinical factor. The PBCD34+ count was overall a stronger predictor of 6 month blood counts than was the total CD34+ cells/kg infused. Both factors retained their significance in multivariate analysis, controlling for clinical factors. In conclusion, subsets of CD34+ cells and clinical factors are inferior to the total CD34+ cell dose/kg and PBCD34+ count in predicting 6 month blood counts following ASCT.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/sj.bmt.1702708", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1096890", 
        "issn": [
          "0268-3369", 
          "1476-5365"
        ], 
        "name": "Bone Marrow Transplantation", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "12", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "26"
      }
    ], 
    "name": "Predictive factors for long-term engraftment of autologous blood stem cells", 
    "pagination": "1299", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "9e403e09fbee309ce83ffb4aa3f2dd4c7909dd5ba0d0c66e15aabd70716e8556"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "11223969"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8702459"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.bmt.1702708"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1033218958"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.bmt.1702708", 
      "https://app.dimensions.ai/details/publication/pub.1033218958"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8669_00000425.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/1702708"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.bmt.1702708'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.bmt.1702708'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.bmt.1702708'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.bmt.1702708'


 

This table displays all metadata directly associated to this object as RDF triples.

296 TRIPLES      21 PREDICATES      76 URIs      40 LITERALS      28 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.bmt.1702708 schema:about N12426396bad64ca6b5ec025899e4919b
2 N14a19ec3f721453196ec0cfd37340641
3 N17545cdc86f14ef8a03b38343ca95a5a
4 N2d207856878142d7843dbd1a33bd3c9a
5 N3e89e79746c94ee3a065aa3974481ffb
6 N55c7b634d9ee49b786a8dbdefabda688
7 N5896c5e2260845b6895b76282961036d
8 N6f769d306a5b43cca611e4d6b8c7b22f
9 N732f2d0331b0437db24c5bfce5bfadb7
10 N893851b18d004fbc9ed45ff2bb4409a5
11 N926e1d0661644d4ba529bfc3ef5a2ac9
12 N98be1e9333534ebb9b76cf054798e6a2
13 Na11f6afdcc6244d1b314193c350b7524
14 Ncea2b58f3e204cffbac31aeee0aed4cf
15 Ndc25a31d6cbd4c149ff1ae78cb6d8591
16 Ne30c4d6f791c47aaa0894a4d878ec76f
17 Nee20eae416fd4ebc845b67e4e190d5c8
18 Nf20d477ef2e64cc890320313cf41b65c
19 Nf54b107f8d2143c7a71cc054876ce5c1
20 anzsrc-for:11
21 anzsrc-for:1102
22 schema:author Ne73e0c5f123b41bda2aa2a280f789f8a
23 schema:citation sg:pub.10.1038/2023
24 sg:pub.10.1038/sj.bmt.1700671
25 sg:pub.10.1038/sj.bmt.1701536
26 sg:pub.10.1038/sj.bmt.1701800
27 sg:pub.10.1038/sj.bmt.1701886
28 sg:pub.10.1038/sj.bmt.1701923
29 sg:pub.10.1038/sj.bmt.1702066
30 https://app.dimensions.ai/details/publication/pub.1074475442
31 https://app.dimensions.ai/details/publication/pub.1075303764
32 https://app.dimensions.ai/details/publication/pub.1077312306
33 https://app.dimensions.ai/details/publication/pub.1077336840
34 https://app.dimensions.ai/details/publication/pub.1079470070
35 https://app.dimensions.ai/details/publication/pub.1082399515
36 https://app.dimensions.ai/details/publication/pub.1082421977
37 https://app.dimensions.ai/details/publication/pub.1082467296
38 https://app.dimensions.ai/details/publication/pub.1082504032
39 https://app.dimensions.ai/details/publication/pub.1082854040
40 https://app.dimensions.ai/details/publication/pub.1082926477
41 https://app.dimensions.ai/details/publication/pub.1083249356
42 https://app.dimensions.ai/details/publication/pub.1083263798
43 https://doi.org/10.1046/j.1365-2141.1998.01066.x
44 https://doi.org/10.1046/j.1537-2995.1998.38498257378.x
45 https://doi.org/10.1089/152581699320090
46 https://doi.org/10.1111/j.1600-0609.1989.tb01203.x
47 https://doi.org/10.1172/jci113658
48 https://doi.org/10.1200/jco.1997.15.3.1218
49 https://doi.org/10.1200/jco.1998.16.6.2093
50 https://doi.org/10.1200/jco.1999.17.10.3128
51 schema:datePublished 2000-12
52 schema:datePublishedReg 2000-12-01
53 schema:description Data from 170 consecutive patients aged 19-66 years (median age 46 years) who underwent unmanipulated autologous blood stem cell transplant (ASCT) were analyzed to determine if total CD34+ cells/kg infused, CD34+ subsets (CD34+41+, CD34+90+, CD34+33-, CD34+38-, CD34+38-DR-), peripheral blood CD34+ cell (PBCD34+) count on first apheresis day, or various clinical factors were associated with low blood counts 6 months post ASCT. Thirty-four patients were excluded from analysis either because of death (n = 17) or re-induction chemotherapy prior to 6 months post ASCT (n = 13), or because of lack of follow-up data (n = 4). Of the remaining 136 patients, 46% had low WBC ( < 4 x 10(9)/l), 41% low platelets (<150 x 10(9)/l), and 34% low hemoglobin ( < 120 g/l) at a median of 6 months following ASCT. By Spearman's rank correlation, both the total CD34+ cell dose/kg and the PBCD34+ count correlated with 6 month blood counts better than any subset of CD34+ cells or any clinical factor. The PBCD34+ count was overall a stronger predictor of 6 month blood counts than was the total CD34+ cells/kg infused. Both factors retained their significance in multivariate analysis, controlling for clinical factors. In conclusion, subsets of CD34+ cells and clinical factors are inferior to the total CD34+ cell dose/kg and PBCD34+ count in predicting 6 month blood counts following ASCT.
54 schema:genre research_article
55 schema:inLanguage en
56 schema:isAccessibleForFree true
57 schema:isPartOf N450034ba0b804271a4c6cf4f39127807
58 N9ffacfc48e6c4f3f8baa5104677745ac
59 sg:journal.1096890
60 schema:name Predictive factors for long-term engraftment of autologous blood stem cells
61 schema:pagination 1299
62 schema:productId N07ef1a329fad42f08e21caf7e42cf87d
63 N7895c415a9144d299c4a61822ad94961
64 N7c339fbe3c4f47f88cfaebfef0ff1831
65 N8020ba4465464c70b5fc393f0d56cb90
66 Nd74e6a3cf8c1448d9c94dd1f79525e09
67 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033218958
68 https://doi.org/10.1038/sj.bmt.1702708
69 schema:sdDatePublished 2019-04-10T16:29
70 schema:sdLicense https://scigraph.springernature.com/explorer/license/
71 schema:sdPublisher Nd9d4ac1992d64578ac970faa6ea8dfb6
72 schema:url https://www.nature.com/articles/1702708
73 sgo:license sg:explorer/license/
74 sgo:sdDataset articles
75 rdf:type schema:ScholarlyArticle
76 N07ef1a329fad42f08e21caf7e42cf87d schema:name nlm_unique_id
77 schema:value 8702459
78 rdf:type schema:PropertyValue
79 N12426396bad64ca6b5ec025899e4919b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Retrospective Studies
81 rdf:type schema:DefinedTerm
82 N14a19ec3f721453196ec0cfd37340641 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Blood Cell Count
84 rdf:type schema:DefinedTerm
85 N17545cdc86f14ef8a03b38343ca95a5a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Adult
87 rdf:type schema:DefinedTerm
88 N1d6b9ba936c44995b8442204f200d8b2 rdf:first sg:person.0602537007.72
89 rdf:rest N613a80cf15be4407a4c7afef6d406696
90 N2d207856878142d7843dbd1a33bd3c9a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Transplantation, Autologous
92 rdf:type schema:DefinedTerm
93 N3da3cf40b1404ac4abc3b16b405e4364 rdf:first sg:person.010012722342.01
94 rdf:rest rdf:nil
95 N3e89e79746c94ee3a065aa3974481ffb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Neoplasms
97 rdf:type schema:DefinedTerm
98 N450034ba0b804271a4c6cf4f39127807 schema:issueNumber 12
99 rdf:type schema:PublicationIssue
100 N4f911466dfef4d75b8ff9e7a2c5dce33 rdf:first sg:person.01021516770.65
101 rdf:rest Nebe5d1a262a845c393543927803349c4
102 N55c7b634d9ee49b786a8dbdefabda688 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Statistics, Nonparametric
104 rdf:type schema:DefinedTerm
105 N5896c5e2260845b6895b76282961036d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Hematopoietic Stem Cell Transplantation
107 rdf:type schema:DefinedTerm
108 N613a80cf15be4407a4c7afef6d406696 rdf:first sg:person.010322301312.07
109 rdf:rest N4f911466dfef4d75b8ff9e7a2c5dce33
110 N69b26af624c44d7d8fa1d0e98b3b6c74 rdf:first sg:person.0642105445.51
111 rdf:rest N1d6b9ba936c44995b8442204f200d8b2
112 N6eefce9ad4f543a7b292ac0c6b3d5662 rdf:first sg:person.01262500314.13
113 rdf:rest Nadb34bb92a3946049a8bc3794149ad3c
114 N6f769d306a5b43cca611e4d6b8c7b22f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Follow-Up Studies
116 rdf:type schema:DefinedTerm
117 N732f2d0331b0437db24c5bfce5bfadb7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Blood Transfusion, Autologous
119 rdf:type schema:DefinedTerm
120 N7895c415a9144d299c4a61822ad94961 schema:name readcube_id
121 schema:value 9e403e09fbee309ce83ffb4aa3f2dd4c7909dd5ba0d0c66e15aabd70716e8556
122 rdf:type schema:PropertyValue
123 N7c339fbe3c4f47f88cfaebfef0ff1831 schema:name dimensions_id
124 schema:value pub.1033218958
125 rdf:type schema:PropertyValue
126 N8020ba4465464c70b5fc393f0d56cb90 schema:name pubmed_id
127 schema:value 11223969
128 rdf:type schema:PropertyValue
129 N893851b18d004fbc9ed45ff2bb4409a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Prognosis
131 rdf:type schema:DefinedTerm
132 N926e1d0661644d4ba529bfc3ef5a2ac9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Immunophenotyping
134 rdf:type schema:DefinedTerm
135 N98be1e9333534ebb9b76cf054798e6a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Humans
137 rdf:type schema:DefinedTerm
138 N9ffacfc48e6c4f3f8baa5104677745ac schema:volumeNumber 26
139 rdf:type schema:PublicationVolume
140 Na11f6afdcc6244d1b314193c350b7524 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Female
142 rdf:type schema:DefinedTerm
143 Nadb34bb92a3946049a8bc3794149ad3c rdf:first sg:person.01110664210.35
144 rdf:rest N69b26af624c44d7d8fa1d0e98b3b6c74
145 Ncea2b58f3e204cffbac31aeee0aed4cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Middle Aged
147 rdf:type schema:DefinedTerm
148 Nd7002b89b9d2466396ae77a55a71f0be rdf:first sg:person.01335500110.37
149 rdf:rest N6eefce9ad4f543a7b292ac0c6b3d5662
150 Nd74e6a3cf8c1448d9c94dd1f79525e09 schema:name doi
151 schema:value 10.1038/sj.bmt.1702708
152 rdf:type schema:PropertyValue
153 Nd9d4ac1992d64578ac970faa6ea8dfb6 schema:name Springer Nature - SN SciGraph project
154 rdf:type schema:Organization
155 Ndc25a31d6cbd4c149ff1ae78cb6d8591 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Aged
157 rdf:type schema:DefinedTerm
158 Ne11c78d4aa3c4a6b8f89becf92a5a01b rdf:first sg:person.016436141052.65
159 rdf:rest N3da3cf40b1404ac4abc3b16b405e4364
160 Ne30c4d6f791c47aaa0894a4d878ec76f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Male
162 rdf:type schema:DefinedTerm
163 Ne73e0c5f123b41bda2aa2a280f789f8a rdf:first sg:person.01203325067.03
164 rdf:rest Nd7002b89b9d2466396ae77a55a71f0be
165 Nebe5d1a262a845c393543927803349c4 rdf:first sg:person.013025421422.11
166 rdf:rest Ne11c78d4aa3c4a6b8f89becf92a5a01b
167 Nee20eae416fd4ebc845b67e4e190d5c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Antigens, CD34
169 rdf:type schema:DefinedTerm
170 Nf20d477ef2e64cc890320313cf41b65c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Predictive Value of Tests
172 rdf:type schema:DefinedTerm
173 Nf54b107f8d2143c7a71cc054876ce5c1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Graft Survival
175 rdf:type schema:DefinedTerm
176 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
177 schema:name Medical and Health Sciences
178 rdf:type schema:DefinedTerm
179 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
180 schema:name Cardiorespiratory Medicine and Haematology
181 rdf:type schema:DefinedTerm
182 sg:journal.1096890 schema:issn 0268-3369
183 1476-5365
184 schema:name Bone Marrow Transplantation
185 rdf:type schema:Periodical
186 sg:person.010012722342.01 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
187 schema:familyName Stewart
188 schema:givenName DA
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010012722342.01
190 rdf:type schema:Person
191 sg:person.01021516770.65 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
192 schema:familyName Glück
193 schema:givenName S
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021516770.65
195 rdf:type schema:Person
196 sg:person.010322301312.07 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
197 schema:familyName Morris
198 schema:givenName D
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010322301312.07
200 rdf:type schema:Person
201 sg:person.01110664210.35 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
202 schema:familyName Auer
203 schema:givenName I
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110664210.35
205 rdf:type schema:Person
206 sg:person.01203325067.03 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
207 schema:familyName Duggan
208 schema:givenName PR
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203325067.03
210 rdf:type schema:Person
211 sg:person.01262500314.13 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
212 schema:familyName Luider
213 schema:givenName J
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262500314.13
215 rdf:type schema:Person
216 sg:person.013025421422.11 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
217 schema:familyName Brown
218 schema:givenName CB
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013025421422.11
220 rdf:type schema:Person
221 sg:person.01335500110.37 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
222 schema:familyName Guo
223 schema:givenName D
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335500110.37
225 rdf:type schema:Person
226 sg:person.016436141052.65 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
227 schema:familyName Russell
228 schema:givenName JA
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016436141052.65
230 rdf:type schema:Person
231 sg:person.0602537007.72 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
232 schema:familyName Chaudhry
233 schema:givenName A
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602537007.72
235 rdf:type schema:Person
236 sg:person.0642105445.51 schema:affiliation https://www.grid.ac/institutes/grid.22072.35
237 schema:familyName Klassen
238 schema:givenName J
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642105445.51
240 rdf:type schema:Person
241 sg:pub.10.1038/2023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007795844
242 https://doi.org/10.1038/2023
243 rdf:type schema:CreativeWork
244 sg:pub.10.1038/sj.bmt.1700671 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009413018
245 https://doi.org/10.1038/sj.bmt.1700671
246 rdf:type schema:CreativeWork
247 sg:pub.10.1038/sj.bmt.1701536 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012603980
248 https://doi.org/10.1038/sj.bmt.1701536
249 rdf:type schema:CreativeWork
250 sg:pub.10.1038/sj.bmt.1701800 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043720114
251 https://doi.org/10.1038/sj.bmt.1701800
252 rdf:type schema:CreativeWork
253 sg:pub.10.1038/sj.bmt.1701886 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043233916
254 https://doi.org/10.1038/sj.bmt.1701886
255 rdf:type schema:CreativeWork
256 sg:pub.10.1038/sj.bmt.1701923 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030376103
257 https://doi.org/10.1038/sj.bmt.1701923
258 rdf:type schema:CreativeWork
259 sg:pub.10.1038/sj.bmt.1702066 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032914551
260 https://doi.org/10.1038/sj.bmt.1702066
261 rdf:type schema:CreativeWork
262 https://app.dimensions.ai/details/publication/pub.1074475442 schema:CreativeWork
263 https://app.dimensions.ai/details/publication/pub.1075303764 schema:CreativeWork
264 https://app.dimensions.ai/details/publication/pub.1077312306 schema:CreativeWork
265 https://app.dimensions.ai/details/publication/pub.1077336840 schema:CreativeWork
266 https://app.dimensions.ai/details/publication/pub.1079470070 schema:CreativeWork
267 https://app.dimensions.ai/details/publication/pub.1082399515 schema:CreativeWork
268 https://app.dimensions.ai/details/publication/pub.1082421977 schema:CreativeWork
269 https://app.dimensions.ai/details/publication/pub.1082467296 schema:CreativeWork
270 https://app.dimensions.ai/details/publication/pub.1082504032 schema:CreativeWork
271 https://app.dimensions.ai/details/publication/pub.1082854040 schema:CreativeWork
272 https://app.dimensions.ai/details/publication/pub.1082926477 schema:CreativeWork
273 https://app.dimensions.ai/details/publication/pub.1083249356 schema:CreativeWork
274 https://app.dimensions.ai/details/publication/pub.1083263798 schema:CreativeWork
275 https://doi.org/10.1046/j.1365-2141.1998.01066.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008014842
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1046/j.1537-2995.1998.38498257378.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021546267
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1089/152581699320090 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059213504
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1111/j.1600-0609.1989.tb01203.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026595034
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1172/jci113658 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036807911
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1200/jco.1997.15.3.1218 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083057241
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1200/jco.1998.16.6.2093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083277776
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1200/jco.1999.17.10.3128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074528549
290 rdf:type schema:CreativeWork
291 https://www.grid.ac/institutes/grid.22072.35 schema:alternateName University of Calgary
292 schema:name Department of Apheresis, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada
293 Department of Epidemiology, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada
294 Department of Flow Cytometry, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada
295 Department of Medicine, Tom Baker Cancer Center, Foothills Hospital, and University of Calgary, Calgary, Alberta, Canada
296 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...