Juvenile myelomonocytic leukemia relapsing after allogeneic bone marrow transplantation successfully treated with interferon-alpha View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-09-01

AUTHORS

H Ohta, M Kawai, A Sawada, S Tokimasa, H Fujisaki, Y Matsuda, Y Osugi, S Okada, J Hara

ABSTRACT

We report a 5-year-old boy with juvenile myelomonocytic leukemia (JMML) which relapsed after an allogeneic bone marrow transplant who was successfully treated with interferon-α (IFN-α). One year after starting the therapy, he remains clinically well and in complete remission while continuing treatment with IFN-α and bestatin. Although the precise mechanism by which remission was induced is uncertain, a GVL effect combined with a direct antileukemia effect of IFN-α may be responsible. Further assessment of the role of IFN-α in relapsed JMLL patients is warranted. Bone Marrow Transplantation (2000) 26, 681–683. More... »

PAGES

681-683

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bmt.1702584

DOI

http://dx.doi.org/10.1038/sj.bmt.1702584

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1002605496

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11041570


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