Phase II study of docetaxel in patients with metastatic pancreatic cancer: a Japanese cooperative study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1999-04-09

AUTHORS

S Okada, Y Sakata, S Matsuno, M Kurihara, Y Sasaki, Y Ohashi, T Taguchi

ABSTRACT

Docetaxel has been reported to show promising anti-tumour activity in pancreatic ductal cancer (PC). This study was conducted to evaluate the activity and toxicity of moderate-dose (60 mg m−2) docetaxel in Japanese chemo-naive patients with measurable metastatic PC. The patients had a performance status of 0–2. They received docetaxel intravenously over a 1- to 2-h period without any premedication for hypersensitivity reactions. This treatment was repeated every 3–4 weeks with dose adjustments based on the toxic effects observed. Twenty-one patients were eligible and treated with docetaxel. The median number of courses was 2 (range, 1–4). None of the patients achieved an objective response; seven showed no change and 13 showed progressive disease. In one patient, the response was not assessable because of early death. The median survival time for all patients was 118 days. The main grade 3–4 toxicities by patient were leucocytopenia (67%) and neutropenia (86%). Other grade 3–4 toxicities included anaemia (10%), thrombocytopenia (5%), nausea/vomiting (29%), anorexia (29%), GOT/GPT increase (10%), alkaline phosphatase increase (14%), malaise/fatigue (33%) and alopecia (24%). In conclusion, docetaxel, administered on this schedule, did not show significant anti-tumour activity in patients with metastatic PC. More... »

PAGES

438-443

Journal

TITLE

British Journal of Cancer

ISSUE

3-4

VOLUME

80

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bjc.6690375

DOI

http://dx.doi.org/10.1038/sj.bjc.6690375

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041986165

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10408850


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antineoplastic Agents, Phytogenic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma, Ductal, Breast", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Docetaxel", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lung Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymphatic Metastasis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ovarian Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Paclitaxel", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pancreatic Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Taxoids", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.272242.3", 
          "name": [
            "Department of Internal Medicine, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Okada", 
        "givenName": "S", 
        "id": "sg:person.0751215304.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751215304.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Gastroenterology and Endoscopy, Aomori Prefectural Central Hospital, 2-1-1 Higashi Tsukurimichi, Aomori-shi, 030-0913, Aomori, Japan", 
          "id": "http://www.grid.ac/institutes/grid.413825.9", 
          "name": [
            "Department of Gastroenterology and Endoscopy, Aomori Prefectural Central Hospital, 2-1-1 Higashi Tsukurimichi, Aomori-shi, 030-0913, Aomori, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sakata", 
        "givenName": "Y", 
        "id": "sg:person.011653372052.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011653372052.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery I, Tohoku University School of Medicine, 2-1 Seiryocho, Aoba-ku, Sendai-shi, 980-0873, Miyagi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.69566.3a", 
          "name": [
            "Department of Surgery I, Tohoku University School of Medicine, 2-1 Seiryocho, Aoba-ku, Sendai-shi, 980-0873, Miyagi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsuno", 
        "givenName": "S", 
        "id": "sg:person.01272710323.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272710323.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Gastroenterology, Toyosu Hospital, Showa University, 4-1-18 Toyosu, Koto-ku, 135-8577, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.410714.7", 
          "name": [
            "Department of Gastroenterology, Toyosu Hospital, Showa University, 4-1-18 Toyosu, Koto-ku, 135-8577, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kurihara", 
        "givenName": "M", 
        "id": "sg:person.01276170366.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276170366.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Oncology/Hematology and Clinical Pharmacology, National Cancer Hospital East, 6-5-1 Kashiwanoha, Kashiwa-shi, 277-0882, Chiba, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Oncology/Hematology and Clinical Pharmacology, National Cancer Hospital East, 6-5-1 Kashiwanoha, Kashiwa-shi, 277-0882, Chiba, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sasaki", 
        "givenName": "Y", 
        "id": "sg:person.012146667532.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012146667532.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Epidemiology and Biostatistics, School of Health Science and Nursing, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-0033, Tokyo, Japan", 
          "id": "http://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Epidemiology and Biostatistics, School of Health Science and Nursing, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-0033, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ohashi", 
        "givenName": "Y", 
        "id": "sg:person.016471405272.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016471405272.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Japan Society for Cancer Chemotherapy, 1-18-35 Edobori, Nishi-ku, 550-0014, Osaka, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Japan Society for Cancer Chemotherapy, 1-18-35 Edobori, Nishi-ku, 550-0014, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Taguchi", 
        "givenName": "T", 
        "id": "sg:person.016552720302.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016552720302.09"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/bjc.1994.311", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048698803", 
          "https://doi.org/10.1038/bjc.1994.311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1996.416", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010047401", 
          "https://doi.org/10.1038/bjc.1996.416"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1996.37", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016856397", 
          "https://doi.org/10.1038/bjc.1996.37"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/277665a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005302260", 
          "https://doi.org/10.1038/277665a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1999-04-09", 
    "datePublishedReg": "1999-04-09", 
    "description": "Docetaxel has been reported to show promising anti-tumour activity in pancreatic ductal cancer (PC). This study was conducted to evaluate the activity and toxicity of moderate-dose (60 mg m\u22122) docetaxel in Japanese chemo-naive patients with measurable metastatic PC. The patients had a performance status of 0\u20132. They received docetaxel intravenously over a 1- to 2-h period without any premedication for hypersensitivity reactions. This treatment was repeated every 3\u20134 weeks with dose adjustments based on the toxic effects observed. Twenty-one patients were eligible and treated with docetaxel. The median number of courses was 2 (range, 1\u20134). None of the patients achieved an objective response; seven showed no change and 13 showed progressive disease. In one patient, the response was not assessable because of early death. The median survival time for all patients was 118 days. The main grade 3\u20134 toxicities by patient were leucocytopenia (67%) and neutropenia (86%). Other grade 3\u20134 toxicities included anaemia (10%), thrombocytopenia (5%), nausea/vomiting (29%), anorexia (29%), GOT/GPT increase (10%), alkaline phosphatase increase (14%), malaise/fatigue (33%) and alopecia (24%). In conclusion, docetaxel, administered on this schedule, did not show significant anti-tumour activity in patients with metastatic PC.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/sj.bjc.6690375", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1017082", 
        "issn": [
          "0007-0920", 
          "1532-1827"
        ], 
        "name": "British Journal of Cancer", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3-4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "80"
      }
    ], 
    "keywords": [
      "pancreatic ductal cancer", 
      "anti-tumor activity", 
      "grade 3", 
      "promising anti-tumor activity", 
      "main grade 3", 
      "malaise/fatigue", 
      "Japanese cooperative study", 
      "nausea/vomiting", 
      "chemo-naive patients", 
      "phase II study", 
      "metastatic pancreatic cancer", 
      "significant anti-tumor activity", 
      "median survival time", 
      "performance status", 
      "objective response", 
      "progressive disease", 
      "II study", 
      "ductal cancer", 
      "dose adjustment", 
      "alkaline phosphatase increase", 
      "hypersensitivity reactions", 
      "pancreatic cancer", 
      "median number", 
      "survival time", 
      "early death", 
      "patients", 
      "docetaxel", 
      "Cooperative Study", 
      "toxic effects", 
      "cancer", 
      "toxicity", 
      "neutropenia", 
      "vomiting", 
      "premedication", 
      "leucocytopenia", 
      "thrombocytopenia", 
      "anorexia", 
      "anemia", 
      "alopecia", 
      "disease", 
      "activity", 
      "weeks", 
      "response", 
      "study", 
      "death", 
      "treatment", 
      "days", 
      "increase", 
      "conclusion", 
      "status", 
      "fatigue", 
      "course", 
      "adjustment", 
      "period", 
      "schedule", 
      "effect", 
      "changes", 
      "number", 
      "time", 
      "reaction"
    ], 
    "name": "Phase II study of docetaxel in patients with metastatic pancreatic cancer: a Japanese cooperative study", 
    "pagination": "438-443", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1041986165"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.bjc.6690375"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "10408850"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.bjc.6690375", 
      "https://app.dimensions.ai/details/publication/pub.1041986165"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_323.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/sj.bjc.6690375"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690375'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690375'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690375'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690375'


 

This table displays all metadata directly associated to this object as RDF triples.

260 TRIPLES      21 PREDICATES      105 URIs      93 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.bjc.6690375 schema:about N24772ce52c284aaf97b3e75832284e01
2 N28f8990f58004b32a786b89e309f5001
3 N3a43a9e1220f4afcab02651c2a8909d6
4 N3d92e8a7770e403b8e95be40a9401216
5 N4075509cc55941a6a160efbbd613b40c
6 N4cc61c5ee31f48b792102c97a1a01689
7 N633b36297679406c994e726f827b8893
8 N70c6d20051424159a9642230e7f689ba
9 N8da3c49a4c4d4ef08c39f377abf4143a
10 Na2f23e6755b94c4eacfe4bd42f477489
11 Na8dd14e275cc460b99140e5d08a1fb96
12 Nb906d04b24ae48a6adc9cca782ed54b1
13 Nbb11d47ce67e440c9676ad86634e3203
14 Nc73b3e021ce7423c85db09ebb08011f8
15 Nd023b552edd54b87a6123c38cb905633
16 Nd772ba9c60544fd8a45767ec4e8b9b30
17 anzsrc-for:11
18 anzsrc-for:1112
19 schema:author N176c53f70b2049f28d4f4fea21942692
20 schema:citation sg:pub.10.1038/277665a0
21 sg:pub.10.1038/bjc.1994.311
22 sg:pub.10.1038/bjc.1996.37
23 sg:pub.10.1038/bjc.1996.416
24 schema:datePublished 1999-04-09
25 schema:datePublishedReg 1999-04-09
26 schema:description Docetaxel has been reported to show promising anti-tumour activity in pancreatic ductal cancer (PC). This study was conducted to evaluate the activity and toxicity of moderate-dose (60 mg m−2) docetaxel in Japanese chemo-naive patients with measurable metastatic PC. The patients had a performance status of 0–2. They received docetaxel intravenously over a 1- to 2-h period without any premedication for hypersensitivity reactions. This treatment was repeated every 3–4 weeks with dose adjustments based on the toxic effects observed. Twenty-one patients were eligible and treated with docetaxel. The median number of courses was 2 (range, 1–4). None of the patients achieved an objective response; seven showed no change and 13 showed progressive disease. In one patient, the response was not assessable because of early death. The median survival time for all patients was 118 days. The main grade 3–4 toxicities by patient were leucocytopenia (67%) and neutropenia (86%). Other grade 3–4 toxicities included anaemia (10%), thrombocytopenia (5%), nausea/vomiting (29%), anorexia (29%), GOT/GPT increase (10%), alkaline phosphatase increase (14%), malaise/fatigue (33%) and alopecia (24%). In conclusion, docetaxel, administered on this schedule, did not show significant anti-tumour activity in patients with metastatic PC.
27 schema:genre article
28 schema:isAccessibleForFree true
29 schema:isPartOf N9cac816467134963aab3b0077f27ec26
30 N9d2b01fc8ffc41fcae176a5c587c6f26
31 sg:journal.1017082
32 schema:keywords Cooperative Study
33 II study
34 Japanese cooperative study
35 activity
36 adjustment
37 alkaline phosphatase increase
38 alopecia
39 anemia
40 anorexia
41 anti-tumor activity
42 cancer
43 changes
44 chemo-naive patients
45 conclusion
46 course
47 days
48 death
49 disease
50 docetaxel
51 dose adjustment
52 ductal cancer
53 early death
54 effect
55 fatigue
56 grade 3
57 hypersensitivity reactions
58 increase
59 leucocytopenia
60 main grade 3
61 malaise/fatigue
62 median number
63 median survival time
64 metastatic pancreatic cancer
65 nausea/vomiting
66 neutropenia
67 number
68 objective response
69 pancreatic cancer
70 pancreatic ductal cancer
71 patients
72 performance status
73 period
74 phase II study
75 premedication
76 progressive disease
77 promising anti-tumor activity
78 reaction
79 response
80 schedule
81 significant anti-tumor activity
82 status
83 study
84 survival time
85 thrombocytopenia
86 time
87 toxic effects
88 toxicity
89 treatment
90 vomiting
91 weeks
92 schema:name Phase II study of docetaxel in patients with metastatic pancreatic cancer: a Japanese cooperative study
93 schema:pagination 438-443
94 schema:productId N0341faa58c394d5485235d8699d357cf
95 N8f9dd2c998f145d9b9e42db4db81ab98
96 Ne71c84473f7c4609acf91a638f222363
97 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041986165
98 https://doi.org/10.1038/sj.bjc.6690375
99 schema:sdDatePublished 2022-10-01T06:31
100 schema:sdLicense https://scigraph.springernature.com/explorer/license/
101 schema:sdPublisher N678ce61d6df042998657fbbff5b7b207
102 schema:url https://doi.org/10.1038/sj.bjc.6690375
103 sgo:license sg:explorer/license/
104 sgo:sdDataset articles
105 rdf:type schema:ScholarlyArticle
106 N0341faa58c394d5485235d8699d357cf schema:name doi
107 schema:value 10.1038/sj.bjc.6690375
108 rdf:type schema:PropertyValue
109 N0a1af7ecd18d4623ab6e5a18de82cac7 rdf:first sg:person.016552720302.09
110 rdf:rest rdf:nil
111 N1397371d98fa4f71bede38d51345fee1 rdf:first sg:person.012146667532.55
112 rdf:rest N2f9fbc5033a349b8afac40903b78e6df
113 N176c53f70b2049f28d4f4fea21942692 rdf:first sg:person.0751215304.80
114 rdf:rest Ncf3e65df0acd48b6bbe11074a338863c
115 N24772ce52c284aaf97b3e75832284e01 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Lymphatic Metastasis
117 rdf:type schema:DefinedTerm
118 N28f8990f58004b32a786b89e309f5001 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Pancreatic Neoplasms
120 rdf:type schema:DefinedTerm
121 N2f9fbc5033a349b8afac40903b78e6df rdf:first sg:person.016471405272.86
122 rdf:rest N0a1af7ecd18d4623ab6e5a18de82cac7
123 N3a43a9e1220f4afcab02651c2a8909d6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Ovarian Neoplasms
125 rdf:type schema:DefinedTerm
126 N3d92e8a7770e403b8e95be40a9401216 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Paclitaxel
128 rdf:type schema:DefinedTerm
129 N4075509cc55941a6a160efbbd613b40c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Taxoids
131 rdf:type schema:DefinedTerm
132 N454557700c7d434da3a4e5748197d6ed rdf:first sg:person.01272710323.06
133 rdf:rest Nd85d0a7f81444bb19ddfd8b9f3eabfbb
134 N4cc61c5ee31f48b792102c97a1a01689 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Carcinoma, Ductal, Breast
136 rdf:type schema:DefinedTerm
137 N633b36297679406c994e726f827b8893 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Male
139 rdf:type schema:DefinedTerm
140 N678ce61d6df042998657fbbff5b7b207 schema:name Springer Nature - SN SciGraph project
141 rdf:type schema:Organization
142 N70c6d20051424159a9642230e7f689ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Lung Neoplasms
144 rdf:type schema:DefinedTerm
145 N8da3c49a4c4d4ef08c39f377abf4143a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Antineoplastic Agents, Phytogenic
147 rdf:type schema:DefinedTerm
148 N8f9dd2c998f145d9b9e42db4db81ab98 schema:name pubmed_id
149 schema:value 10408850
150 rdf:type schema:PropertyValue
151 N9cac816467134963aab3b0077f27ec26 schema:issueNumber 3-4
152 rdf:type schema:PublicationIssue
153 N9d2b01fc8ffc41fcae176a5c587c6f26 schema:volumeNumber 80
154 rdf:type schema:PublicationVolume
155 Na2f23e6755b94c4eacfe4bd42f477489 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Liver Neoplasms
157 rdf:type schema:DefinedTerm
158 Na8dd14e275cc460b99140e5d08a1fb96 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Adult
160 rdf:type schema:DefinedTerm
161 Nb906d04b24ae48a6adc9cca782ed54b1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Female
163 rdf:type schema:DefinedTerm
164 Nbb11d47ce67e440c9676ad86634e3203 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Humans
166 rdf:type schema:DefinedTerm
167 Nc73b3e021ce7423c85db09ebb08011f8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Middle Aged
169 rdf:type schema:DefinedTerm
170 Ncf3e65df0acd48b6bbe11074a338863c rdf:first sg:person.011653372052.41
171 rdf:rest N454557700c7d434da3a4e5748197d6ed
172 Nd023b552edd54b87a6123c38cb905633 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Docetaxel
174 rdf:type schema:DefinedTerm
175 Nd772ba9c60544fd8a45767ec4e8b9b30 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Aged
177 rdf:type schema:DefinedTerm
178 Nd85d0a7f81444bb19ddfd8b9f3eabfbb rdf:first sg:person.01276170366.00
179 rdf:rest N1397371d98fa4f71bede38d51345fee1
180 Ne71c84473f7c4609acf91a638f222363 schema:name dimensions_id
181 schema:value pub.1041986165
182 rdf:type schema:PropertyValue
183 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
184 schema:name Medical and Health Sciences
185 rdf:type schema:DefinedTerm
186 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
187 schema:name Oncology and Carcinogenesis
188 rdf:type schema:DefinedTerm
189 sg:journal.1017082 schema:issn 0007-0920
190 1532-1827
191 schema:name British Journal of Cancer
192 schema:publisher Springer Nature
193 rdf:type schema:Periodical
194 sg:person.011653372052.41 schema:affiliation grid-institutes:grid.413825.9
195 schema:familyName Sakata
196 schema:givenName Y
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011653372052.41
198 rdf:type schema:Person
199 sg:person.012146667532.55 schema:affiliation grid-institutes:None
200 schema:familyName Sasaki
201 schema:givenName Y
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012146667532.55
203 rdf:type schema:Person
204 sg:person.01272710323.06 schema:affiliation grid-institutes:grid.69566.3a
205 schema:familyName Matsuno
206 schema:givenName S
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272710323.06
208 rdf:type schema:Person
209 sg:person.01276170366.00 schema:affiliation grid-institutes:grid.410714.7
210 schema:familyName Kurihara
211 schema:givenName M
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276170366.00
213 rdf:type schema:Person
214 sg:person.016471405272.86 schema:affiliation grid-institutes:grid.26999.3d
215 schema:familyName Ohashi
216 schema:givenName Y
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016471405272.86
218 rdf:type schema:Person
219 sg:person.016552720302.09 schema:affiliation grid-institutes:None
220 schema:familyName Taguchi
221 schema:givenName T
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016552720302.09
223 rdf:type schema:Person
224 sg:person.0751215304.80 schema:affiliation grid-institutes:grid.272242.3
225 schema:familyName Okada
226 schema:givenName S
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751215304.80
228 rdf:type schema:Person
229 sg:pub.10.1038/277665a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005302260
230 https://doi.org/10.1038/277665a0
231 rdf:type schema:CreativeWork
232 sg:pub.10.1038/bjc.1994.311 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048698803
233 https://doi.org/10.1038/bjc.1994.311
234 rdf:type schema:CreativeWork
235 sg:pub.10.1038/bjc.1996.37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016856397
236 https://doi.org/10.1038/bjc.1996.37
237 rdf:type schema:CreativeWork
238 sg:pub.10.1038/bjc.1996.416 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010047401
239 https://doi.org/10.1038/bjc.1996.416
240 rdf:type schema:CreativeWork
241 grid-institutes:None schema:alternateName Department of Oncology/Hematology and Clinical Pharmacology, National Cancer Hospital East, 6-5-1 Kashiwanoha, Kashiwa-shi, 277-0882, Chiba, Japan
242 Japan Society for Cancer Chemotherapy, 1-18-35 Edobori, Nishi-ku, 550-0014, Osaka, Japan
243 schema:name Department of Oncology/Hematology and Clinical Pharmacology, National Cancer Hospital East, 6-5-1 Kashiwanoha, Kashiwa-shi, 277-0882, Chiba, Japan
244 Japan Society for Cancer Chemotherapy, 1-18-35 Edobori, Nishi-ku, 550-0014, Osaka, Japan
245 rdf:type schema:Organization
246 grid-institutes:grid.26999.3d schema:alternateName Department of Epidemiology and Biostatistics, School of Health Science and Nursing, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-0033, Tokyo, Japan
247 schema:name Department of Epidemiology and Biostatistics, School of Health Science and Nursing, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-0033, Tokyo, Japan
248 rdf:type schema:Organization
249 grid-institutes:grid.272242.3 schema:alternateName Department of Internal Medicine, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan
250 schema:name Department of Internal Medicine, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan
251 rdf:type schema:Organization
252 grid-institutes:grid.410714.7 schema:alternateName Department of Gastroenterology, Toyosu Hospital, Showa University, 4-1-18 Toyosu, Koto-ku, 135-8577, Tokyo, Japan
253 schema:name Department of Gastroenterology, Toyosu Hospital, Showa University, 4-1-18 Toyosu, Koto-ku, 135-8577, Tokyo, Japan
254 rdf:type schema:Organization
255 grid-institutes:grid.413825.9 schema:alternateName Department of Gastroenterology and Endoscopy, Aomori Prefectural Central Hospital, 2-1-1 Higashi Tsukurimichi, Aomori-shi, 030-0913, Aomori, Japan
256 schema:name Department of Gastroenterology and Endoscopy, Aomori Prefectural Central Hospital, 2-1-1 Higashi Tsukurimichi, Aomori-shi, 030-0913, Aomori, Japan
257 rdf:type schema:Organization
258 grid-institutes:grid.69566.3a schema:alternateName Department of Surgery I, Tohoku University School of Medicine, 2-1 Seiryocho, Aoba-ku, Sendai-shi, 980-0873, Miyagi, Japan
259 schema:name Department of Surgery I, Tohoku University School of Medicine, 2-1 Seiryocho, Aoba-ku, Sendai-shi, 980-0873, Miyagi, Japan
260 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...