Genetic aberrations in glioblastoma multiforme: translocation of chromosome 10 in an O-2A-like cell line View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1999-02

AUTHORS

X Mao, T A Jones, I Tomlinson, A J Rowan, L I Fedorova, A V Zelenin, J-I Mao, N J Gutowski, M Noble, D Sheer

ABSTRACT

We have examined the genetic aberrations in two near-diploid glioblastoma multiforme cell lines that appear to have arisen from different glial lineages. One cell line, Hu-O-2A/Gb1, expresses antigens and metabolic profiles characteristic of the oligodendrocyte-type-2 astrocyte (0-2A) lineage of the rat central nervous system. This line generates, in vitro, cells with characteristics of 0-2A progenitor cells, oligodendrocytes and astrocytes. The second cell line, IN1434, is derived from an astrocyte or a precursor cell restricted to astrocytic differentiation. In Hu-O-2A/Gb1 the sole homologue of chromosome 10 is disrupted at band 10p11-12.1 by translocation with chromosomes X and 15. The translocation breakpoint is localized between genetic markers D10S2103 and [D10S637, D10S1962, D10S355]. Other aberrations include a 5;14 translocation, deletion of the long and short arms of chromosome 16 and loss of one copy of the CDKN2 gene. IN1434 cells share some cytogenetic abnormalities with Hu-O-2A/Gb1 cells, despite their apparent derivation from a different biological origin, but also have translocations involving the long and short arms of chromosome 1 and the long arm of chromosome 7, and deletion of chromosome 13 at bands 13q12-21. More... »

PAGES

724

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bjc.6690116

DOI

http://dx.doi.org/10.1038/sj.bjc.6690116

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048620595

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10070860


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Astrocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Aberrations", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Human, Pair 10", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glioblastoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Karyotyping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microsatellite Repeats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oligodendroglia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Translocation, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Cells, Cultured", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Cancer Research UK", 
          "id": "https://www.grid.ac/institutes/grid.11485.39", 
          "name": [
            "Human Cytogenetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mao", 
        "givenName": "X", 
        "id": "sg:person.015305060457.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015305060457.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Research UK", 
          "id": "https://www.grid.ac/institutes/grid.11485.39", 
          "name": [
            "Cancer Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jones", 
        "givenName": "T A", 
        "id": "sg:person.01331611417.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331611417.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Research UK", 
          "id": "https://www.grid.ac/institutes/grid.11485.39", 
          "name": [
            "Cancer Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tomlinson", 
        "givenName": "I", 
        "id": "sg:person.013001172722.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013001172722.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Research UK", 
          "id": "https://www.grid.ac/institutes/grid.11485.39", 
          "name": [
            "Cancer Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rowan", 
        "givenName": "A J", 
        "id": "sg:person.0700015771.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700015771.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Research UK", 
          "id": "https://www.grid.ac/institutes/grid.11485.39", 
          "name": [
            "Cancer Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fedorova", 
        "givenName": "L I", 
        "id": "sg:person.01267156622.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267156622.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Research UK", 
          "id": "https://www.grid.ac/institutes/grid.11485.39", 
          "name": [
            "Cancer Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zelenin", 
        "givenName": "A V", 
        "id": "sg:person.01156001456.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156001456.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Genomics and Technology Development, Genome Therapeutics Corp., 100 Beaver Street, Waltham, MA, 02154, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mao", 
        "givenName": "J-I", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Genomics and Technology Development, Genome Therapeutics Corp., 100 Beaver Street, Waltham, MA, 02154, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gutowski", 
        "givenName": "N J", 
        "id": "sg:person.0603713557.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603713557.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Ludwig Institute for Cancer Research, 91 Riding House Street, London , W1P 8BT, UK", 
            "Genomics and Technology Development, Genome Therapeutics Corp., 100 Beaver Street, Waltham, MA, 02154, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Noble", 
        "givenName": "M", 
        "id": "sg:person.01270713326.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270713326.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Research UK", 
          "id": "https://www.grid.ac/institutes/grid.11485.39", 
          "name": [
            "Human Cytogenetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sheer", 
        "givenName": "D", 
        "id": "sg:person.0631740114.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631740114.24"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0304-3835(93)90149-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007959040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00219686", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009107581", 
          "https://doi.org/10.1007/bf00219686"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.76.10.4913", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010508055"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/glia.440150304", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011834041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/glia.440150304", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011834041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.275.5308.1943", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014605015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.79.8.2709", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014615739"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000133559", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015049742"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0165-4608(95)00085-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016013406"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0012-1606(81)90477-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018037795"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.76.1.514", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021408894"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.1994.1345", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021691383"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gcc.2870120407", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023043204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1098-1004(1997)9:1<7::aid-humu2>3.0.co;2-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023422877"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0165-4608(95)00129-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024327274"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000134432", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024840522"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02815353", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025292730", 
          "https://doi.org/10.1007/bf02815353"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02815353", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025292730", 
          "https://doi.org/10.1007/bf02815353"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0888-7543(95)80025-h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026308301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0888-7543(95)80025-h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026308301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.2910600615", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026754843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm0296-169", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028904279", 
          "https://doi.org/10.1038/nm0296-169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005072-199501000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031226686"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/dbio.1993.1033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032083464"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0997-32", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032249080", 
          "https://doi.org/10.1038/ng0997-32"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000134411", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033689719"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1098-2264(199805)22:1<9::aid-gcc2>3.0.co;2-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035389698"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1098-2264(199805)22:1<9::aid-gcc2>3.0.co;2-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035389698"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0694supp-246", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042223854", 
          "https://doi.org/10.1038/ng0694supp-246"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0694supp-246", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042223854", 
          "https://doi.org/10.1038/ng0694supp-246"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gcc.2870060402", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044364868"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(72)90398-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045166106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(72)90398-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045166106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199503303321302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045772912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/368753a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045854758", 
          "https://doi.org/10.1038/368753a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/303390a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046522629", 
          "https://doi.org/10.1038/303390a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0497-356", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048219802", 
          "https://doi.org/10.1038/ng0497-356"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0497-356", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048219802", 
          "https://doi.org/10.1038/ng0497-356"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1098-2264(199604)15:4<199::aid-gcc1>3.0.co;2-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048764908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.8153634", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062652972"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078552729", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1984.tb02122.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1081807987"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.04-07-01892.1984", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1081930567"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082377805", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082552339", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082798097", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082854615", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082884136", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082924727", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1999-02", 
    "datePublishedReg": "1999-02-01", 
    "description": "We have examined the genetic aberrations in two near-diploid glioblastoma multiforme cell lines that appear to have arisen from different glial lineages. One cell line, Hu-O-2A/Gb1, expresses antigens and metabolic profiles characteristic of the oligodendrocyte-type-2 astrocyte (0-2A) lineage of the rat central nervous system. This line generates, in vitro, cells with characteristics of 0-2A progenitor cells, oligodendrocytes and astrocytes. The second cell line, IN1434, is derived from an astrocyte or a precursor cell restricted to astrocytic differentiation. In Hu-O-2A/Gb1 the sole homologue of chromosome 10 is disrupted at band 10p11-12.1 by translocation with chromosomes X and 15. The translocation breakpoint is localized between genetic markers D10S2103 and [D10S637, D10S1962, D10S355]. Other aberrations include a 5;14 translocation, deletion of the long and short arms of chromosome 16 and loss of one copy of the CDKN2 gene. IN1434 cells share some cytogenetic abnormalities with Hu-O-2A/Gb1 cells, despite their apparent derivation from a different biological origin, but also have translocations involving the long and short arms of chromosome 1 and the long arm of chromosome 7, and deletion of chromosome 13 at bands 13q12-21.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/sj.bjc.6690116", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5147977", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1017082", 
        "issn": [
          "0007-0920", 
          "1532-1827"
        ], 
        "name": "British Journal of Cancer", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "79"
      }
    ], 
    "name": "Genetic aberrations in glioblastoma multiforme: translocation of chromosome 10 in an O-2A-like cell line", 
    "pagination": "724", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "e79ea739e0fdb5994e1fca3e7cd07f392099a9c01be731c7f571f69b4fd6e748"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "10070860"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0370635"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.bjc.6690116"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1048620595"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.bjc.6690116", 
      "https://app.dimensions.ai/details/publication/pub.1048620595"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T11:56", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000359_0000000359/records_29215_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/6690116"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690116'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690116'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690116'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6690116'


 

This table displays all metadata directly associated to this object as RDF triples.

337 TRIPLES      21 PREDICATES      88 URIs      38 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.bjc.6690116 schema:about N1083c19c3dc44f7d8163b349211971fb
2 N3c4092c0c5894f14b2e33b98c0e99a1d
3 N3cb0f7a35ec7468a8185bba247e34fb1
4 N3dc0bbb29e0142ed8ce3e239b3f60401
5 N41009cf9c4054376aad580941d43be7b
6 N4163321da84444a2a1db3c621ad238c7
7 N4a683be60deb4fd997caa5a2f77cce64
8 N5754d7e814224b608c0d6069187e2159
9 N64046bddb7da42daa5d58876da30b27e
10 N66fa569330f14439af9e306b50da4635
11 N6b1e2c41ec89460fa6186b1a15477036
12 N744ac23b2dc84fd9a2dd2833d2f11155
13 N892644ffc72742b590352d327ad4f5c0
14 Nb93c1e776a1a40a8a8d22262ac17d7d0
15 Nc4046f527bbf4a07ab3846ba99290b4c
16 Ne16f141164c643c2b1f2710f00b70288
17 Nf683935e36cf484288d42d0b6a78acad
18 anzsrc-for:06
19 anzsrc-for:0604
20 schema:author N3d7400bced0445769b43bd1645bef11a
21 schema:citation sg:pub.10.1007/bf00219686
22 sg:pub.10.1007/bf02815353
23 sg:pub.10.1038/303390a0
24 sg:pub.10.1038/368753a0
25 sg:pub.10.1038/ng0497-356
26 sg:pub.10.1038/ng0694supp-246
27 sg:pub.10.1038/ng0997-32
28 sg:pub.10.1038/nm0296-169
29 https://app.dimensions.ai/details/publication/pub.1078552729
30 https://app.dimensions.ai/details/publication/pub.1082377805
31 https://app.dimensions.ai/details/publication/pub.1082552339
32 https://app.dimensions.ai/details/publication/pub.1082798097
33 https://app.dimensions.ai/details/publication/pub.1082854615
34 https://app.dimensions.ai/details/publication/pub.1082884136
35 https://app.dimensions.ai/details/publication/pub.1082924727
36 https://doi.org/10.1002/(sici)1098-1004(1997)9:1<7::aid-humu2>3.0.co;2-8
37 https://doi.org/10.1002/(sici)1098-2264(199604)15:4<199::aid-gcc1>3.0.co;2-x
38 https://doi.org/10.1002/(sici)1098-2264(199805)22:1<9::aid-gcc2>3.0.co;2-1
39 https://doi.org/10.1002/gcc.2870060402
40 https://doi.org/10.1002/gcc.2870120407
41 https://doi.org/10.1002/glia.440150304
42 https://doi.org/10.1002/ijc.2910600615
43 https://doi.org/10.1002/j.1460-2075.1984.tb02122.x
44 https://doi.org/10.1006/dbio.1993.1033
45 https://doi.org/10.1006/geno.1994.1345
46 https://doi.org/10.1016/0006-8993(72)90398-8
47 https://doi.org/10.1016/0012-1606(81)90477-2
48 https://doi.org/10.1016/0165-4608(95)00085-2
49 https://doi.org/10.1016/0165-4608(95)00129-8
50 https://doi.org/10.1016/0304-3835(93)90149-4
51 https://doi.org/10.1016/0888-7543(95)80025-h
52 https://doi.org/10.1056/nejm199503303321302
53 https://doi.org/10.1073/pnas.76.1.514
54 https://doi.org/10.1073/pnas.76.10.4913
55 https://doi.org/10.1073/pnas.79.8.2709
56 https://doi.org/10.1097/00005072-199501000-00011
57 https://doi.org/10.1126/science.275.5308.1943
58 https://doi.org/10.1126/science.8153634
59 https://doi.org/10.1159/000133559
60 https://doi.org/10.1159/000134411
61 https://doi.org/10.1159/000134432
62 https://doi.org/10.1523/jneurosci.04-07-01892.1984
63 schema:datePublished 1999-02
64 schema:datePublishedReg 1999-02-01
65 schema:description We have examined the genetic aberrations in two near-diploid glioblastoma multiforme cell lines that appear to have arisen from different glial lineages. One cell line, Hu-O-2A/Gb1, expresses antigens and metabolic profiles characteristic of the oligodendrocyte-type-2 astrocyte (0-2A) lineage of the rat central nervous system. This line generates, in vitro, cells with characteristics of 0-2A progenitor cells, oligodendrocytes and astrocytes. The second cell line, IN1434, is derived from an astrocyte or a precursor cell restricted to astrocytic differentiation. In Hu-O-2A/Gb1 the sole homologue of chromosome 10 is disrupted at band 10p11-12.1 by translocation with chromosomes X and 15. The translocation breakpoint is localized between genetic markers D10S2103 and [D10S637, D10S1962, D10S355]. Other aberrations include a 5;14 translocation, deletion of the long and short arms of chromosome 16 and loss of one copy of the CDKN2 gene. IN1434 cells share some cytogenetic abnormalities with Hu-O-2A/Gb1 cells, despite their apparent derivation from a different biological origin, but also have translocations involving the long and short arms of chromosome 1 and the long arm of chromosome 7, and deletion of chromosome 13 at bands 13q12-21.
66 schema:genre research_article
67 schema:inLanguage en
68 schema:isAccessibleForFree true
69 schema:isPartOf N6c627e63ce3d422fbd555af0fbb0278a
70 N8e0a8695b2264408a938993e5c07c01d
71 sg:journal.1017082
72 schema:name Genetic aberrations in glioblastoma multiforme: translocation of chromosome 10 in an O-2A-like cell line
73 schema:pagination 724
74 schema:productId N3046cb1cdb0e400da137d8c317f800ba
75 N6892b04544874625b5b1f07e1fd0ad3c
76 Na3ac5ce105ef4f56acac76e2cc066e8b
77 Nc13882a8e2794d789a8548fae4a0b1dd
78 Ndc68d3f1bb054b8b8a218b39e286a59f
79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048620595
80 https://doi.org/10.1038/sj.bjc.6690116
81 schema:sdDatePublished 2019-04-11T11:56
82 schema:sdLicense https://scigraph.springernature.com/explorer/license/
83 schema:sdPublisher N4259abda46894fd1ab467e6ee63f2680
84 schema:url https://www.nature.com/articles/6690116
85 sgo:license sg:explorer/license/
86 sgo:sdDataset articles
87 rdf:type schema:ScholarlyArticle
88 N096f8bcae1a5494c9e440a4a98f3692e rdf:first sg:person.01156001456.49
89 rdf:rest Nc16eb9f3f4154002873da0a6f8aa7394
90 N1083c19c3dc44f7d8163b349211971fb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Chromosomes, Human, Pair 10
92 rdf:type schema:DefinedTerm
93 N3046cb1cdb0e400da137d8c317f800ba schema:name nlm_unique_id
94 schema:value 0370635
95 rdf:type schema:PropertyValue
96 N3c4092c0c5894f14b2e33b98c0e99a1d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Male
98 rdf:type schema:DefinedTerm
99 N3cb0f7a35ec7468a8185bba247e34fb1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Chromosome Aberrations
101 rdf:type schema:DefinedTerm
102 N3d7400bced0445769b43bd1645bef11a rdf:first sg:person.015305060457.83
103 rdf:rest N92b5cd5f331b40e980be837581477b72
104 N3dc0bbb29e0142ed8ce3e239b3f60401 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Tumor Cells, Cultured
106 rdf:type schema:DefinedTerm
107 N41009cf9c4054376aad580941d43be7b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Humans
109 rdf:type schema:DefinedTerm
110 N4163321da84444a2a1db3c621ad238c7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Brain Neoplasms
112 rdf:type schema:DefinedTerm
113 N4259abda46894fd1ab467e6ee63f2680 schema:name Springer Nature - SN SciGraph project
114 rdf:type schema:Organization
115 N4600fe4647ee4b1aada33839f50e990b rdf:first sg:person.0631740114.24
116 rdf:rest rdf:nil
117 N4a683be60deb4fd997caa5a2f77cce64 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Karyotyping
119 rdf:type schema:DefinedTerm
120 N5754d7e814224b608c0d6069187e2159 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Oligodendroglia
122 rdf:type schema:DefinedTerm
123 N64046bddb7da42daa5d58876da30b27e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Cell Line
125 rdf:type schema:DefinedTerm
126 N66fa569330f14439af9e306b50da4635 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Middle Aged
128 rdf:type schema:DefinedTerm
129 N67f62ad538bb4d8ca8be3bb8e4d5ead4 rdf:first sg:person.0700015771.26
130 rdf:rest Nae504a0772f74a3692c997a81db9b86a
131 N6892b04544874625b5b1f07e1fd0ad3c schema:name readcube_id
132 schema:value e79ea739e0fdb5994e1fca3e7cd07f392099a9c01be731c7f571f69b4fd6e748
133 rdf:type schema:PropertyValue
134 N6b1e2c41ec89460fa6186b1a15477036 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Chromosome Mapping
136 rdf:type schema:DefinedTerm
137 N6c627e63ce3d422fbd555af0fbb0278a schema:issueNumber 5
138 rdf:type schema:PublicationIssue
139 N744ac23b2dc84fd9a2dd2833d2f11155 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Rats
141 rdf:type schema:DefinedTerm
142 N86694ae3f29340799b505992fa802b84 rdf:first sg:person.013001172722.66
143 rdf:rest N67f62ad538bb4d8ca8be3bb8e4d5ead4
144 N892644ffc72742b590352d327ad4f5c0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Animals
146 rdf:type schema:DefinedTerm
147 N8e0a8695b2264408a938993e5c07c01d schema:volumeNumber 79
148 rdf:type schema:PublicationVolume
149 N92b5cd5f331b40e980be837581477b72 rdf:first sg:person.01331611417.76
150 rdf:rest N86694ae3f29340799b505992fa802b84
151 Na3ac5ce105ef4f56acac76e2cc066e8b schema:name pubmed_id
152 schema:value 10070860
153 rdf:type schema:PropertyValue
154 Nae504a0772f74a3692c997a81db9b86a rdf:first sg:person.01267156622.35
155 rdf:rest N096f8bcae1a5494c9e440a4a98f3692e
156 Nb93c1e776a1a40a8a8d22262ac17d7d0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Glioblastoma
158 rdf:type schema:DefinedTerm
159 Nc13882a8e2794d789a8548fae4a0b1dd schema:name dimensions_id
160 schema:value pub.1048620595
161 rdf:type schema:PropertyValue
162 Nc16eb9f3f4154002873da0a6f8aa7394 rdf:first Ndf0faab4455f494b9e897f0e4d758dfd
163 rdf:rest Ncb40254c86284d3e9f496734c1af97c0
164 Nc4046f527bbf4a07ab3846ba99290b4c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Microsatellite Repeats
166 rdf:type schema:DefinedTerm
167 Ncb40254c86284d3e9f496734c1af97c0 rdf:first sg:person.0603713557.11
168 rdf:rest Ned617e8ea4344db9aa691fbd4a82c0fe
169 Ncb69092dc7564514a30378dc6d88ff92 schema:name Genomics and Technology Development, Genome Therapeutics Corp., 100 Beaver Street, Waltham, MA, 02154, USA
170 rdf:type schema:Organization
171 Nd3136a7425254af4b74dfa84ea801e27 schema:name Genomics and Technology Development, Genome Therapeutics Corp., 100 Beaver Street, Waltham, MA, 02154, USA
172 rdf:type schema:Organization
173 Ndc68d3f1bb054b8b8a218b39e286a59f schema:name doi
174 schema:value 10.1038/sj.bjc.6690116
175 rdf:type schema:PropertyValue
176 Ndf0faab4455f494b9e897f0e4d758dfd schema:affiliation Ncb69092dc7564514a30378dc6d88ff92
177 schema:familyName Mao
178 schema:givenName J-I
179 rdf:type schema:Person
180 Ne16f141164c643c2b1f2710f00b70288 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Translocation, Genetic
182 rdf:type schema:DefinedTerm
183 Ned617e8ea4344db9aa691fbd4a82c0fe rdf:first sg:person.01270713326.86
184 rdf:rest N4600fe4647ee4b1aada33839f50e990b
185 Nf683935e36cf484288d42d0b6a78acad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Astrocytes
187 rdf:type schema:DefinedTerm
188 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
189 schema:name Biological Sciences
190 rdf:type schema:DefinedTerm
191 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
192 schema:name Genetics
193 rdf:type schema:DefinedTerm
194 sg:grant.5147977 http://pending.schema.org/fundedItem sg:pub.10.1038/sj.bjc.6690116
195 rdf:type schema:MonetaryGrant
196 sg:journal.1017082 schema:issn 0007-0920
197 1532-1827
198 schema:name British Journal of Cancer
199 rdf:type schema:Periodical
200 sg:person.01156001456.49 schema:affiliation https://www.grid.ac/institutes/grid.11485.39
201 schema:familyName Zelenin
202 schema:givenName A V
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156001456.49
204 rdf:type schema:Person
205 sg:person.01267156622.35 schema:affiliation https://www.grid.ac/institutes/grid.11485.39
206 schema:familyName Fedorova
207 schema:givenName L I
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267156622.35
209 rdf:type schema:Person
210 sg:person.01270713326.86 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
211 schema:familyName Noble
212 schema:givenName M
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270713326.86
214 rdf:type schema:Person
215 sg:person.013001172722.66 schema:affiliation https://www.grid.ac/institutes/grid.11485.39
216 schema:familyName Tomlinson
217 schema:givenName I
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013001172722.66
219 rdf:type schema:Person
220 sg:person.01331611417.76 schema:affiliation https://www.grid.ac/institutes/grid.11485.39
221 schema:familyName Jones
222 schema:givenName T A
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331611417.76
224 rdf:type schema:Person
225 sg:person.015305060457.83 schema:affiliation https://www.grid.ac/institutes/grid.11485.39
226 schema:familyName Mao
227 schema:givenName X
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015305060457.83
229 rdf:type schema:Person
230 sg:person.0603713557.11 schema:affiliation Nd3136a7425254af4b74dfa84ea801e27
231 schema:familyName Gutowski
232 schema:givenName N J
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603713557.11
234 rdf:type schema:Person
235 sg:person.0631740114.24 schema:affiliation https://www.grid.ac/institutes/grid.11485.39
236 schema:familyName Sheer
237 schema:givenName D
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631740114.24
239 rdf:type schema:Person
240 sg:person.0700015771.26 schema:affiliation https://www.grid.ac/institutes/grid.11485.39
241 schema:familyName Rowan
242 schema:givenName A J
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700015771.26
244 rdf:type schema:Person
245 sg:pub.10.1007/bf00219686 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009107581
246 https://doi.org/10.1007/bf00219686
247 rdf:type schema:CreativeWork
248 sg:pub.10.1007/bf02815353 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025292730
249 https://doi.org/10.1007/bf02815353
250 rdf:type schema:CreativeWork
251 sg:pub.10.1038/303390a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046522629
252 https://doi.org/10.1038/303390a0
253 rdf:type schema:CreativeWork
254 sg:pub.10.1038/368753a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045854758
255 https://doi.org/10.1038/368753a0
256 rdf:type schema:CreativeWork
257 sg:pub.10.1038/ng0497-356 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048219802
258 https://doi.org/10.1038/ng0497-356
259 rdf:type schema:CreativeWork
260 sg:pub.10.1038/ng0694supp-246 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042223854
261 https://doi.org/10.1038/ng0694supp-246
262 rdf:type schema:CreativeWork
263 sg:pub.10.1038/ng0997-32 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032249080
264 https://doi.org/10.1038/ng0997-32
265 rdf:type schema:CreativeWork
266 sg:pub.10.1038/nm0296-169 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028904279
267 https://doi.org/10.1038/nm0296-169
268 rdf:type schema:CreativeWork
269 https://app.dimensions.ai/details/publication/pub.1078552729 schema:CreativeWork
270 https://app.dimensions.ai/details/publication/pub.1082377805 schema:CreativeWork
271 https://app.dimensions.ai/details/publication/pub.1082552339 schema:CreativeWork
272 https://app.dimensions.ai/details/publication/pub.1082798097 schema:CreativeWork
273 https://app.dimensions.ai/details/publication/pub.1082854615 schema:CreativeWork
274 https://app.dimensions.ai/details/publication/pub.1082884136 schema:CreativeWork
275 https://app.dimensions.ai/details/publication/pub.1082924727 schema:CreativeWork
276 https://doi.org/10.1002/(sici)1098-1004(1997)9:1<7::aid-humu2>3.0.co;2-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023422877
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1002/(sici)1098-2264(199604)15:4<199::aid-gcc1>3.0.co;2-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048764908
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1002/(sici)1098-2264(199805)22:1<9::aid-gcc2>3.0.co;2-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035389698
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1002/gcc.2870060402 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044364868
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1002/gcc.2870120407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023043204
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1002/glia.440150304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011834041
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1002/ijc.2910600615 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026754843
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1002/j.1460-2075.1984.tb02122.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1081807987
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1006/dbio.1993.1033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032083464
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1006/geno.1994.1345 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021691383
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1016/0006-8993(72)90398-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045166106
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1016/0012-1606(81)90477-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018037795
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1016/0165-4608(95)00085-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016013406
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1016/0165-4608(95)00129-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024327274
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1016/0304-3835(93)90149-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007959040
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1016/0888-7543(95)80025-h schema:sameAs https://app.dimensions.ai/details/publication/pub.1026308301
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1056/nejm199503303321302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045772912
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1073/pnas.76.1.514 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021408894
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1073/pnas.76.10.4913 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010508055
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1073/pnas.79.8.2709 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014615739
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1097/00005072-199501000-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031226686
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1126/science.275.5308.1943 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014605015
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1126/science.8153634 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062652972
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1159/000133559 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015049742
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1159/000134411 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033689719
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1159/000134432 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024840522
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1523/jneurosci.04-07-01892.1984 schema:sameAs https://app.dimensions.ai/details/publication/pub.1081930567
329 rdf:type schema:CreativeWork
330 https://www.grid.ac/institutes/grid.11485.39 schema:alternateName Cancer Research UK
331 schema:name Cancer Genetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK
332 Human Cytogenetics Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK
333 rdf:type schema:Organization
334 https://www.grid.ac/institutes/grid.4991.5 schema:alternateName University of Oxford
335 schema:name Genomics and Technology Development, Genome Therapeutics Corp., 100 Beaver Street, Waltham, MA, 02154, USA
336 Ludwig Institute for Cancer Research, 91 Riding House Street, London , W1P 8BT, UK
337 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...