The effect of self-sampled HPV testing on participation to cervical cancer screening in Italy: a randomised controlled trial (ISRCTN96071600) View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-01

AUTHORS

P Giorgi Rossi, L M Marsili, L Camilloni, A Iossa, A Lattanzi, C Sani, C Di Pierro, G Grazzini, C Angeloni, P Capparucci, A Pellegrini, M L Schiboni, A Sperati, M Confortini, C Bellanova, A D'Addetta, E Mania, C B Visioli, E Sereno, F Carozzi,

ABSTRACT

BACKGROUND: In Italy, cervical cancer screening programmes actively invite women aged 25-64 years. Programmes are hindered by low participation. METHODS: A sample of non-responder women aged 35-64 years, belonging to three different programmes (in Rome, Florence and Teramo), was randomly split into four arms: two control groups received standard recall letters to perform either Pap-test (first group) or human papillomavirus (HPV) test (second group) at the clinic. A third arm was sent letters offering a self-sampler for HPV testing, to be requested by phone, whereas a fourth group was directly sent the self-samplers home. RESULTS: Compliance with standard recall was 13.9% (N619). Offering HPV test at the clinic had a nonsignificant effect on compliance (N616, relative risk (RR)=1.08; 95% CI=0.82-1.41). Self-sampler at request had the poorest performance, 8.7% (N622, RR=0.62; 95% CI=0.45-0.86), whereas direct mailing of the self-sampler registered the highest compliance: 19.6% (N616, RR=1.41; 95% CI=1.10-1.82). This effect on compliance was observed only in urban areas, Florence and Rome (N438, RR=1.69; 95% CI=1.24-2.30), but not in Abruzzo (N178, RR=0.95; 95% CI=0.61-1.50), a prevalently rural area. CONCLUSIONS: Mailing self-samplers to non-responders may increase compliance as compared with delivering standard recall letters. Nevertheless, effectiveness is context specific and the strategy costs should be carefully considered. More... »

PAGES

248

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bjc.6606040

DOI

http://dx.doi.org/10.1038/sj.bjc.6606040

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024733384

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21179038


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