Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitors View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-03

AUTHORS

C Lemos, G Jansen, G J Peters

ABSTRACT

Multidrug resistance is often associated with the (over)expression of drug efflux transporters of the ATP-binding cassette (ABC) protein family. This minireview discusses the role of one selected ABC-transporter family member, the breast cancer resistance protein (BCRP/ABCG2), in the (pre)clinical efficacy of novel experimental anticancer drugs, in particular tyrosine kinase inhibitors.

PAGES

6604213

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bjc.6604213

DOI

http://dx.doi.org/10.1038/sj.bjc.6604213

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042547314

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18253130


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