Surgical resection of hepatic metastases from colorectal cancer: A systematic review of published studies View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-03-14

AUTHORS

P C Simmonds, J N Primrose, J L Colquitt, O J Garden, G J Poston, M Rees

ABSTRACT

No consensus on the indications for surgical resection of colorectal liver metastases exists. This systematic review has been undertaken to assess the published evidence for its efficacy and safety and to identify prognostic factors. Studies were identified by computerised and hand searches of the literature, scanning references and contacting investigators. The outcome measures were overall survival, disease-free survival, postoperative morbidity and mortality, quality of life and cost effectiveness, and a qualitative summary of the trends across all studies was produced. Only 30 of 529 independent studies met all the eligibility criteria for the review, and data on 30-day mortality and morbidity only were included from a further nine studies. The best available evidence came from prospective case series, but only two studies reported outcomes for all patients undergoing surgery. The remainder reported outcomes for selected groups of patients: those undergoing hepatic resection or those undergoing curative resection. Postoperative mortality rates were generally low (median 2.8%). The majority of studies described only serious postoperative morbidity, the most common being bile leak and associated perihepatic abscess. Approximately 30% of patients remained alive 5 years after resection and around two-thirds of these are disease free. The quality of the majority of published papers was poor and ascertaining the benefits of surgical resection of colorectal hepatic metastases is difficult in the absence of randomised trials. However, it is clear that there is group of patients with liver metastases who may become long-term disease- free survivors following hepatic resection. Such survival is rare in apparently comparable patients who do not have surgical treatment. Further work is needed to more accurately define this group of patients and to determine whether the addition of adjuvant treatments results in improved survival. More... »

PAGES

982-999

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bjc.6603033

DOI

http://dx.doi.org/10.1038/sj.bjc.6603033

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1051210499

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16538219


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colorectal Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease-Free Survival", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatectomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Morbidity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Postoperative Complications", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quality Control", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quality of Life", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Randomized Controlled Trials as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Cancer Research UK Clinical Centre, MP824, Southampton General Hospital, Tremona Road, SO16 6YD, Southampton, UK", 
          "id": "http://www.grid.ac/institutes/grid.123047.3", 
          "name": [
            "Cancer Research UK Clinical Centre, MP824, Southampton General Hospital, Tremona Road, SO16 6YD, Southampton, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Simmonds", 
        "givenName": "P C", 
        "id": "sg:person.01250766267.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250766267.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Surgery, F Level Centre Block (MP816), Southampton General Hospital, SO16 6YD, Southampton, UK", 
          "id": "http://www.grid.ac/institutes/grid.123047.3", 
          "name": [
            "University Surgery, F Level Centre Block (MP816), Southampton General Hospital, SO16 6YD, Southampton, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Primrose", 
        "givenName": "J N", 
        "id": "sg:person.01250744256.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250744256.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Research UK Clinical Centre, MP824, Southampton General Hospital, Tremona Road, SO16 6YD, Southampton, UK", 
          "id": "http://www.grid.ac/institutes/grid.123047.3", 
          "name": [
            "Cancer Research UK Clinical Centre, MP824, Southampton General Hospital, Tremona Road, SO16 6YD, Southampton, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Colquitt", 
        "givenName": "J L", 
        "id": "sg:person.01044036674.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044036674.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Clinical and Surgical Sciences, Royal Infirmary of Edinburgh, 51 Little France Crescent, Old Dalkeith Road, EH16 4SA, Edinburgh, Scotland, UK", 
          "id": "http://www.grid.ac/institutes/grid.418716.d", 
          "name": [
            "Department of Clinical and Surgical Sciences, Royal Infirmary of Edinburgh, 51 Little France Crescent, Old Dalkeith Road, EH16 4SA, Edinburgh, Scotland, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Garden", 
        "givenName": "O J", 
        "id": "sg:person.015442464064.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015442464064.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, University Hospital Aintree, L9 7AL, Longmoor Lane, Liverpool, UK", 
          "id": "http://www.grid.ac/institutes/grid.411255.6", 
          "name": [
            "Department of Surgery, University Hospital Aintree, L9 7AL, Longmoor Lane, Liverpool, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Poston", 
        "givenName": "G J", 
        "id": "sg:person.0607370647.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607370647.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hepatobiliary Surgery Unit, North Hampshire Hospital, Aldermaston Road, RG24 9NA, Basingstoke, UK", 
          "id": "http://www.grid.ac/institutes/grid.414262.7", 
          "name": [
            "Hepatobiliary Surgery Unit, North Hampshire Hospital, Aldermaston Road, RG24 9NA, Basingstoke, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rees", 
        "givenName": "M", 
        "id": "sg:person.0660705073.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660705073.11"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf02307088", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029055275", 
          "https://doi.org/10.1007/bf02307088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002689900381", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042270745", 
          "https://doi.org/10.1007/s002689900381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02303827", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019191907", 
          "https://doi.org/10.1007/bf02303827"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s002689900404", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045324470", 
          "https://doi.org/10.1007/s002689900404"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02348736", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000331937", 
          "https://doi.org/10.1007/bf02348736"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00316981", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038122014", 
          "https://doi.org/10.1007/bf00316981"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-51873-7_12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1089790174", 
          "https://doi.org/10.1007/978-3-642-51873-7_12"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s001040050484", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046632077", 
          "https://doi.org/10.1007/s001040050484"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2006-03-14", 
    "datePublishedReg": "2006-03-14", 
    "description": "No consensus on the indications for surgical resection of colorectal liver metastases exists. This systematic review has been undertaken to assess the published evidence for its efficacy and safety and to identify prognostic factors. Studies were identified by computerised and hand searches of the literature, scanning references and contacting investigators. The outcome measures were overall survival, disease-free survival, postoperative morbidity and mortality, quality of life and cost effectiveness, and a qualitative summary of the trends across all studies was produced. Only 30 of 529 independent studies met all the eligibility criteria for the review, and data on 30-day mortality and morbidity only were included from a further nine studies. The best available evidence came from prospective case series, but only two studies reported outcomes for all patients undergoing surgery. The remainder reported outcomes for selected groups of patients: those undergoing hepatic resection or those undergoing curative resection. Postoperative mortality rates were generally low (median 2.8%). The majority of studies described only serious postoperative morbidity, the most common being bile leak and associated perihepatic abscess. Approximately 30% of patients remained alive 5 years after resection and around two-thirds of these are disease free. The quality of the majority of published papers was poor and ascertaining the benefits of surgical resection of colorectal hepatic metastases is difficult in the absence of randomised trials. However, it is clear that there is group of patients with liver metastases who may become long-term disease- free survivors following hepatic resection. Such survival is rare in apparently comparable patients who do not have surgical treatment. Further work is needed to more accurately define this group of patients and to determine whether the addition of adjuvant treatments results in improved survival.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/sj.bjc.6603033", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1017082", 
        "issn": [
          "0007-0920", 
          "1532-1827"
        ], 
        "name": "British Journal of Cancer", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "94"
      }
    ], 
    "keywords": [
      "group of patients", 
      "surgical resection", 
      "postoperative morbidity", 
      "liver metastases", 
      "hepatic resection", 
      "hepatic metastases", 
      "systematic review", 
      "long-term disease-free survivors", 
      "serious postoperative morbidity", 
      "adjuvant treatments results", 
      "colorectal liver metastases", 
      "postoperative mortality rate", 
      "disease-free survival", 
      "disease-free survivors", 
      "prospective case series", 
      "colorectal hepatic metastases", 
      "quality of life", 
      "perihepatic abscess", 
      "curative resection", 
      "bile leak", 
      "comparable patients", 
      "overall survival", 
      "prognostic factors", 
      "surgical treatment", 
      "case series", 
      "colorectal cancer", 
      "outcome measures", 
      "resection", 
      "eligibility criteria", 
      "patients", 
      "mortality rate", 
      "treatment results", 
      "hand search", 
      "majority of studies", 
      "metastasis", 
      "morbidity", 
      "available evidence", 
      "survival", 
      "scanning references", 
      "mortality", 
      "two-thirds", 
      "qualitative summary", 
      "outcomes", 
      "cost effectiveness", 
      "review", 
      "group", 
      "independent studies", 
      "such survival", 
      "abscess", 
      "surgery", 
      "majority", 
      "study", 
      "cancer", 
      "disease", 
      "survivors", 
      "trials", 
      "further work", 
      "evidence", 
      "efficacy", 
      "treatment", 
      "indications", 
      "leak", 
      "safety", 
      "investigators", 
      "years", 
      "remainder", 
      "factors", 
      "absence", 
      "consensus", 
      "quality", 
      "criteria", 
      "summary", 
      "life", 
      "benefits", 
      "measures", 
      "rate", 
      "search", 
      "literature", 
      "data", 
      "addition", 
      "effectiveness", 
      "series", 
      "results", 
      "trends", 
      "reference", 
      "work", 
      "paper"
    ], 
    "name": "Surgical resection of hepatic metastases from colorectal cancer: A systematic review of published studies", 
    "pagination": "982-999", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1051210499"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.bjc.6603033"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "16538219"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.bjc.6603033", 
      "https://app.dimensions.ai/details/publication/pub.1051210499"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-10T09:57", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_428.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/sj.bjc.6603033"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6603033'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6603033'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6603033'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6603033'


 

This table displays all metadata directly associated to this object as RDF triples.

275 TRIPLES      22 PREDICATES      133 URIs      117 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.bjc.6603033 schema:about N480c327211d440ba96adceced9d95603
2 N68b4c7fa2a644ca8a08e53b9a82d8139
3 N6aa59f11367d4ba0b4e76bcb203ca87d
4 N6d4dae6c49634a899ccc238e665999cd
5 N7ad62169157d45d6b151609384e8788f
6 N7e79e706ce494a5c9d5c3616f565b308
7 N978218e2e9e142ae86eea5082b99b20c
8 Nafd3449453f34e479f55231f19de3730
9 Nb20531d68f7c41d3a703d4f7c32fb981
10 Nb3462d7a361e4c669467f209c71445bc
11 Nca70dd1847f246d9bdc575a657d7a0d4
12 Nff28365a0a284ba782cc94d4c3ebd84d
13 anzsrc-for:11
14 anzsrc-for:1103
15 schema:author Nda620f4596df45c39f1b085fa9b2563e
16 schema:citation sg:pub.10.1007/978-3-642-51873-7_12
17 sg:pub.10.1007/bf00316981
18 sg:pub.10.1007/bf02303827
19 sg:pub.10.1007/bf02307088
20 sg:pub.10.1007/bf02348736
21 sg:pub.10.1007/s001040050484
22 sg:pub.10.1007/s002689900381
23 sg:pub.10.1007/s002689900404
24 schema:datePublished 2006-03-14
25 schema:datePublishedReg 2006-03-14
26 schema:description No consensus on the indications for surgical resection of colorectal liver metastases exists. This systematic review has been undertaken to assess the published evidence for its efficacy and safety and to identify prognostic factors. Studies were identified by computerised and hand searches of the literature, scanning references and contacting investigators. The outcome measures were overall survival, disease-free survival, postoperative morbidity and mortality, quality of life and cost effectiveness, and a qualitative summary of the trends across all studies was produced. Only 30 of 529 independent studies met all the eligibility criteria for the review, and data on 30-day mortality and morbidity only were included from a further nine studies. The best available evidence came from prospective case series, but only two studies reported outcomes for all patients undergoing surgery. The remainder reported outcomes for selected groups of patients: those undergoing hepatic resection or those undergoing curative resection. Postoperative mortality rates were generally low (median 2.8%). The majority of studies described only serious postoperative morbidity, the most common being bile leak and associated perihepatic abscess. Approximately 30% of patients remained alive 5 years after resection and around two-thirds of these are disease free. The quality of the majority of published papers was poor and ascertaining the benefits of surgical resection of colorectal hepatic metastases is difficult in the absence of randomised trials. However, it is clear that there is group of patients with liver metastases who may become long-term disease- free survivors following hepatic resection. Such survival is rare in apparently comparable patients who do not have surgical treatment. Further work is needed to more accurately define this group of patients and to determine whether the addition of adjuvant treatments results in improved survival.
27 schema:genre article
28 schema:inLanguage en
29 schema:isAccessibleForFree true
30 schema:isPartOf N1fd5732deda64b38b50f3c90a13569b4
31 Ne15219414c4747c48ea0771072a915cb
32 sg:journal.1017082
33 schema:keywords abscess
34 absence
35 addition
36 adjuvant treatments results
37 available evidence
38 benefits
39 bile leak
40 cancer
41 case series
42 colorectal cancer
43 colorectal hepatic metastases
44 colorectal liver metastases
45 comparable patients
46 consensus
47 cost effectiveness
48 criteria
49 curative resection
50 data
51 disease
52 disease-free survival
53 disease-free survivors
54 effectiveness
55 efficacy
56 eligibility criteria
57 evidence
58 factors
59 further work
60 group
61 group of patients
62 hand search
63 hepatic metastases
64 hepatic resection
65 independent studies
66 indications
67 investigators
68 leak
69 life
70 literature
71 liver metastases
72 long-term disease-free survivors
73 majority
74 majority of studies
75 measures
76 metastasis
77 morbidity
78 mortality
79 mortality rate
80 outcome measures
81 outcomes
82 overall survival
83 paper
84 patients
85 perihepatic abscess
86 postoperative morbidity
87 postoperative mortality rate
88 prognostic factors
89 prospective case series
90 qualitative summary
91 quality
92 quality of life
93 rate
94 reference
95 remainder
96 resection
97 results
98 review
99 safety
100 scanning references
101 search
102 series
103 serious postoperative morbidity
104 study
105 such survival
106 summary
107 surgery
108 surgical resection
109 surgical treatment
110 survival
111 survivors
112 systematic review
113 treatment
114 treatment results
115 trends
116 trials
117 two-thirds
118 work
119 years
120 schema:name Surgical resection of hepatic metastases from colorectal cancer: A systematic review of published studies
121 schema:pagination 982-999
122 schema:productId N934324000a4f4a3f850d24f78e8c0c57
123 Naeada0d83d654cc5a83dd15262cb0022
124 Nb1372970593a4def8093d618c2b32f9c
125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051210499
126 https://doi.org/10.1038/sj.bjc.6603033
127 schema:sdDatePublished 2022-05-10T09:57
128 schema:sdLicense https://scigraph.springernature.com/explorer/license/
129 schema:sdPublisher N3d2d975654864252b6511f5b9617506d
130 schema:url https://doi.org/10.1038/sj.bjc.6603033
131 sgo:license sg:explorer/license/
132 sgo:sdDataset articles
133 rdf:type schema:ScholarlyArticle
134 N0b23641ea85c4a4db5089be3503274f0 rdf:first sg:person.0660705073.11
135 rdf:rest rdf:nil
136 N1fd5732deda64b38b50f3c90a13569b4 schema:volumeNumber 94
137 rdf:type schema:PublicationVolume
138 N3d2d975654864252b6511f5b9617506d schema:name Springer Nature - SN SciGraph project
139 rdf:type schema:Organization
140 N3d87992c91f24162a74bc0ff275e1dbd rdf:first sg:person.01250744256.47
141 rdf:rest N57816d36683e45d88e3dcdaa27bd40ef
142 N480c327211d440ba96adceced9d95603 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Morbidity
144 rdf:type schema:DefinedTerm
145 N57816d36683e45d88e3dcdaa27bd40ef rdf:first sg:person.01044036674.77
146 rdf:rest N734496b8dbf94796b78f79f945241d86
147 N68b4c7fa2a644ca8a08e53b9a82d8139 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Quality of Life
149 rdf:type schema:DefinedTerm
150 N6aa59f11367d4ba0b4e76bcb203ca87d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Hepatectomy
152 rdf:type schema:DefinedTerm
153 N6d4dae6c49634a899ccc238e665999cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Colorectal Neoplasms
155 rdf:type schema:DefinedTerm
156 N734496b8dbf94796b78f79f945241d86 rdf:first sg:person.015442464064.38
157 rdf:rest Nb77583af5fa14264a95e7994c147e3ab
158 N7ad62169157d45d6b151609384e8788f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Liver Neoplasms
160 rdf:type schema:DefinedTerm
161 N7e79e706ce494a5c9d5c3616f565b308 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Humans
163 rdf:type schema:DefinedTerm
164 N934324000a4f4a3f850d24f78e8c0c57 schema:name dimensions_id
165 schema:value pub.1051210499
166 rdf:type schema:PropertyValue
167 N978218e2e9e142ae86eea5082b99b20c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Quality Control
169 rdf:type schema:DefinedTerm
170 Naeada0d83d654cc5a83dd15262cb0022 schema:name doi
171 schema:value 10.1038/sj.bjc.6603033
172 rdf:type schema:PropertyValue
173 Nafd3449453f34e479f55231f19de3730 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Treatment Outcome
175 rdf:type schema:DefinedTerm
176 Nb1372970593a4def8093d618c2b32f9c schema:name pubmed_id
177 schema:value 16538219
178 rdf:type schema:PropertyValue
179 Nb20531d68f7c41d3a703d4f7c32fb981 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Prognosis
181 rdf:type schema:DefinedTerm
182 Nb3462d7a361e4c669467f209c71445bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Disease-Free Survival
184 rdf:type schema:DefinedTerm
185 Nb77583af5fa14264a95e7994c147e3ab rdf:first sg:person.0607370647.42
186 rdf:rest N0b23641ea85c4a4db5089be3503274f0
187 Nca70dd1847f246d9bdc575a657d7a0d4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Randomized Controlled Trials as Topic
189 rdf:type schema:DefinedTerm
190 Nda620f4596df45c39f1b085fa9b2563e rdf:first sg:person.01250766267.70
191 rdf:rest N3d87992c91f24162a74bc0ff275e1dbd
192 Ne15219414c4747c48ea0771072a915cb schema:issueNumber 7
193 rdf:type schema:PublicationIssue
194 Nff28365a0a284ba782cc94d4c3ebd84d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
195 schema:name Postoperative Complications
196 rdf:type schema:DefinedTerm
197 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
198 schema:name Medical and Health Sciences
199 rdf:type schema:DefinedTerm
200 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
201 schema:name Clinical Sciences
202 rdf:type schema:DefinedTerm
203 sg:journal.1017082 schema:issn 0007-0920
204 1532-1827
205 schema:name British Journal of Cancer
206 schema:publisher Springer Nature
207 rdf:type schema:Periodical
208 sg:person.01044036674.77 schema:affiliation grid-institutes:grid.123047.3
209 schema:familyName Colquitt
210 schema:givenName J L
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044036674.77
212 rdf:type schema:Person
213 sg:person.01250744256.47 schema:affiliation grid-institutes:grid.123047.3
214 schema:familyName Primrose
215 schema:givenName J N
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250744256.47
217 rdf:type schema:Person
218 sg:person.01250766267.70 schema:affiliation grid-institutes:grid.123047.3
219 schema:familyName Simmonds
220 schema:givenName P C
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250766267.70
222 rdf:type schema:Person
223 sg:person.015442464064.38 schema:affiliation grid-institutes:grid.418716.d
224 schema:familyName Garden
225 schema:givenName O J
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015442464064.38
227 rdf:type schema:Person
228 sg:person.0607370647.42 schema:affiliation grid-institutes:grid.411255.6
229 schema:familyName Poston
230 schema:givenName G J
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607370647.42
232 rdf:type schema:Person
233 sg:person.0660705073.11 schema:affiliation grid-institutes:grid.414262.7
234 schema:familyName Rees
235 schema:givenName M
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660705073.11
237 rdf:type schema:Person
238 sg:pub.10.1007/978-3-642-51873-7_12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1089790174
239 https://doi.org/10.1007/978-3-642-51873-7_12
240 rdf:type schema:CreativeWork
241 sg:pub.10.1007/bf00316981 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038122014
242 https://doi.org/10.1007/bf00316981
243 rdf:type schema:CreativeWork
244 sg:pub.10.1007/bf02303827 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019191907
245 https://doi.org/10.1007/bf02303827
246 rdf:type schema:CreativeWork
247 sg:pub.10.1007/bf02307088 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029055275
248 https://doi.org/10.1007/bf02307088
249 rdf:type schema:CreativeWork
250 sg:pub.10.1007/bf02348736 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000331937
251 https://doi.org/10.1007/bf02348736
252 rdf:type schema:CreativeWork
253 sg:pub.10.1007/s001040050484 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046632077
254 https://doi.org/10.1007/s001040050484
255 rdf:type schema:CreativeWork
256 sg:pub.10.1007/s002689900381 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042270745
257 https://doi.org/10.1007/s002689900381
258 rdf:type schema:CreativeWork
259 sg:pub.10.1007/s002689900404 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045324470
260 https://doi.org/10.1007/s002689900404
261 rdf:type schema:CreativeWork
262 grid-institutes:grid.123047.3 schema:alternateName Cancer Research UK Clinical Centre, MP824, Southampton General Hospital, Tremona Road, SO16 6YD, Southampton, UK
263 University Surgery, F Level Centre Block (MP816), Southampton General Hospital, SO16 6YD, Southampton, UK
264 schema:name Cancer Research UK Clinical Centre, MP824, Southampton General Hospital, Tremona Road, SO16 6YD, Southampton, UK
265 University Surgery, F Level Centre Block (MP816), Southampton General Hospital, SO16 6YD, Southampton, UK
266 rdf:type schema:Organization
267 grid-institutes:grid.411255.6 schema:alternateName Department of Surgery, University Hospital Aintree, L9 7AL, Longmoor Lane, Liverpool, UK
268 schema:name Department of Surgery, University Hospital Aintree, L9 7AL, Longmoor Lane, Liverpool, UK
269 rdf:type schema:Organization
270 grid-institutes:grid.414262.7 schema:alternateName Hepatobiliary Surgery Unit, North Hampshire Hospital, Aldermaston Road, RG24 9NA, Basingstoke, UK
271 schema:name Hepatobiliary Surgery Unit, North Hampshire Hospital, Aldermaston Road, RG24 9NA, Basingstoke, UK
272 rdf:type schema:Organization
273 grid-institutes:grid.418716.d schema:alternateName Department of Clinical and Surgical Sciences, Royal Infirmary of Edinburgh, 51 Little France Crescent, Old Dalkeith Road, EH16 4SA, Edinburgh, Scotland, UK
274 schema:name Department of Clinical and Surgical Sciences, Royal Infirmary of Edinburgh, 51 Little France Crescent, Old Dalkeith Road, EH16 4SA, Edinburgh, Scotland, UK
275 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...