Gap junction communication dynamics and bystander effects from ultrasoft X-rays View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2004-03-02

AUTHORS

G O Edwards, S W Botchway, G Hirst, C W Wharton, J K Chipman, R A Meldrum

ABSTRACT

Gap junctions provide a route for small molecules to pass directly between cells. Toxic species may spread through junctions into 'bystander' cells, which may be exploited in chemotherapy and radiotherapy. However, this may be prevented by junction closure, and therefore an understanding of the dose-dependency of inhibition of communication and bystander effects is important. Low-energy ionising radiation (ultrasoft X-rays) provides a tool for the study of bystander effects because the area of exposure may be carefully controlled, and thus target cells may be clearly defined. Loss of gap junction-mediated intercellular communication between irradiated cells was dose-dependent, indicating that closure of junctions is proportional to dose. Closure was associated with hyperphosphorylation of connexin43. Inhibition of communication occurred in bystander cells but was not proportional to dose. Inhibition of communication at higher radiation doses may restrict the spread of inhibitory factors, thus protecting bystander cells. The reduction in communication that takes place in bystander cells was dependent on cells being in physical contact, and not on the release of signalling factors into the medium. More... »

PAGES

1450-1456

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sj.bjc.6601686

DOI

http://dx.doi.org/10.1038/sj.bjc.6601686

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016179733

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15054470


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1115", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Pharmacology and Pharmaceutical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bystander Effect", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Communication", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Membrane Permeability", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cells, Cultured", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Connexin 43", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dose-Response Relationship, Radiation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gap Junctions", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phosphorylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "X-Rays", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK", 
          "id": "http://www.grid.ac/institutes/grid.6572.6", 
          "name": [
            "School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Edwards", 
        "givenName": "G O", 
        "id": "sg:person.01345113105.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01345113105.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Rutherford Appleton Laboratory, Chilton, Oxfordshire OX11 0QX, UK", 
          "id": "http://www.grid.ac/institutes/grid.76978.37", 
          "name": [
            "Rutherford Appleton Laboratory, Chilton, Oxfordshire OX11 0QX, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Botchway", 
        "givenName": "S W", 
        "id": "sg:person.01342303001.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342303001.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Rutherford Appleton Laboratory, Chilton, Oxfordshire OX11 0QX, UK", 
          "id": "http://www.grid.ac/institutes/grid.76978.37", 
          "name": [
            "Rutherford Appleton Laboratory, Chilton, Oxfordshire OX11 0QX, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hirst", 
        "givenName": "G", 
        "id": "sg:person.013527444104.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013527444104.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK", 
          "id": "http://www.grid.ac/institutes/grid.6572.6", 
          "name": [
            "School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wharton", 
        "givenName": "C W", 
        "id": "sg:person.01033631711.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033631711.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK", 
          "id": "http://www.grid.ac/institutes/grid.6572.6", 
          "name": [
            "School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chipman", 
        "givenName": "J K", 
        "id": "sg:person.01072542354.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072542354.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK", 
          "id": "http://www.grid.ac/institutes/grid.6572.6", 
          "name": [
            "School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Meldrum", 
        "givenName": "R A", 
        "id": "sg:person.01163213535.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163213535.14"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1054/bjoc.2000.1665", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045712049", 
          "https://doi.org/10.1054/bjoc.2000.1665"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/227680a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010419937", 
          "https://doi.org/10.1038/227680a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02110109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027282400", 
          "https://doi.org/10.1007/bf02110109"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2004-03-02", 
    "datePublishedReg": "2004-03-02", 
    "description": "Gap junctions provide a route for small molecules to pass directly between cells. Toxic species may spread through junctions into 'bystander' cells, which may be exploited in chemotherapy and radiotherapy. However, this may be prevented by junction closure, and therefore an understanding of the dose-dependency of inhibition of communication and bystander effects is important. Low-energy ionising radiation (ultrasoft X-rays) provides a tool for the study of bystander effects because the area of exposure may be carefully controlled, and thus target cells may be clearly defined. Loss of gap junction-mediated intercellular communication between irradiated cells was dose-dependent, indicating that closure of junctions is proportional to dose. Closure was associated with hyperphosphorylation of connexin43. Inhibition of communication occurred in bystander cells but was not proportional to dose. Inhibition of communication at higher radiation doses may restrict the spread of inhibitory factors, thus protecting bystander cells. The reduction in communication that takes place in bystander cells was dependent on cells being in physical contact, and not on the release of signalling factors into the medium.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/sj.bjc.6601686", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1017082", 
        "issn": [
          "0007-0920", 
          "1532-1827"
        ], 
        "name": "British Journal of Cancer", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "90"
      }
    ], 
    "keywords": [
      "inhibition of communication", 
      "bystander cells", 
      "bystander effect", 
      "gap junction-mediated intercellular communication", 
      "high radiation doses", 
      "area of exposure", 
      "inhibitory factor", 
      "junction closure", 
      "target cells", 
      "hyperphosphorylation of connexin43", 
      "radiation doses", 
      "gap junctions", 
      "inhibition", 
      "intercellular communication", 
      "cells", 
      "ionising radiation", 
      "chemotherapy", 
      "closure", 
      "radiotherapy", 
      "doses", 
      "factors", 
      "effect", 
      "hyperphosphorylation", 
      "connexin43", 
      "exposure", 
      "junctions", 
      "physical contact", 
      "release", 
      "bystanders", 
      "toxic species", 
      "small molecules", 
      "study", 
      "spread", 
      "reduction", 
      "loss", 
      "contact", 
      "area", 
      "route", 
      "communication", 
      "understanding", 
      "radiation", 
      "molecules", 
      "communication dynamics", 
      "tool", 
      "rays", 
      "medium", 
      "place", 
      "species", 
      "dynamics", 
      "Low-energy ionising radiation", 
      "junction-mediated intercellular communication", 
      "closure of junctions", 
      "Gap junction communication dynamics", 
      "junction communication dynamics"
    ], 
    "name": "Gap junction communication dynamics and bystander effects from ultrasoft X-rays", 
    "pagination": "1450-1456", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1016179733"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/sj.bjc.6601686"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15054470"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/sj.bjc.6601686", 
      "https://app.dimensions.ai/details/publication/pub.1016179733"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T18:08", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_393.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/sj.bjc.6601686"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6601686'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6601686'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6601686'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/sj.bjc.6601686'


 

This table displays all metadata directly associated to this object as RDF triples.

210 TRIPLES      22 PREDICATES      94 URIs      83 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/sj.bjc.6601686 schema:about N129ac92d7c1d4285b9eac0eb548cfc50
2 N15667ff0b6f44b32b6f1fc2f50df9a49
3 N465baf361c21402d890b6284163453ac
4 N5587baf87a2f4740a165cc1319249014
5 N600cb264506f4127870fc7eb5c7bc378
6 N723ebebfc95f42ccac5a619da7888473
7 N7414dc03f0974baf8cf2984dd6db9df1
8 Na4cbf7c5d24b4a6c9f07b8db56aaf6bc
9 Nb2a36d45a1fc4355bf98d8952d052120
10 Nc17ffa3550ff4dffaa625b10ff004c7c
11 Nc3d36648747f41a884c7b0d02a5e7dac
12 anzsrc-for:11
13 anzsrc-for:1115
14 schema:author N7b4d61663b1b4891a6748683195aa6fc
15 schema:citation sg:pub.10.1007/bf02110109
16 sg:pub.10.1038/227680a0
17 sg:pub.10.1054/bjoc.2000.1665
18 schema:datePublished 2004-03-02
19 schema:datePublishedReg 2004-03-02
20 schema:description Gap junctions provide a route for small molecules to pass directly between cells. Toxic species may spread through junctions into 'bystander' cells, which may be exploited in chemotherapy and radiotherapy. However, this may be prevented by junction closure, and therefore an understanding of the dose-dependency of inhibition of communication and bystander effects is important. Low-energy ionising radiation (ultrasoft X-rays) provides a tool for the study of bystander effects because the area of exposure may be carefully controlled, and thus target cells may be clearly defined. Loss of gap junction-mediated intercellular communication between irradiated cells was dose-dependent, indicating that closure of junctions is proportional to dose. Closure was associated with hyperphosphorylation of connexin43. Inhibition of communication occurred in bystander cells but was not proportional to dose. Inhibition of communication at higher radiation doses may restrict the spread of inhibitory factors, thus protecting bystander cells. The reduction in communication that takes place in bystander cells was dependent on cells being in physical contact, and not on the release of signalling factors into the medium.
21 schema:genre article
22 schema:inLanguage en
23 schema:isAccessibleForFree true
24 schema:isPartOf N5ead4bf9f39947d5b30ea7c2356a12a1
25 N5f7394dd03964b2badbdb46086d285ac
26 sg:journal.1017082
27 schema:keywords Gap junction communication dynamics
28 Low-energy ionising radiation
29 area
30 area of exposure
31 bystander cells
32 bystander effect
33 bystanders
34 cells
35 chemotherapy
36 closure
37 closure of junctions
38 communication
39 communication dynamics
40 connexin43
41 contact
42 doses
43 dynamics
44 effect
45 exposure
46 factors
47 gap junction-mediated intercellular communication
48 gap junctions
49 high radiation doses
50 hyperphosphorylation
51 hyperphosphorylation of connexin43
52 inhibition
53 inhibition of communication
54 inhibitory factor
55 intercellular communication
56 ionising radiation
57 junction closure
58 junction communication dynamics
59 junction-mediated intercellular communication
60 junctions
61 loss
62 medium
63 molecules
64 physical contact
65 place
66 radiation
67 radiation doses
68 radiotherapy
69 rays
70 reduction
71 release
72 route
73 small molecules
74 species
75 spread
76 study
77 target cells
78 tool
79 toxic species
80 understanding
81 schema:name Gap junction communication dynamics and bystander effects from ultrasoft X-rays
82 schema:pagination 1450-1456
83 schema:productId N2d7239151cc9467da89c8946db0a18fd
84 Nae98dbac909a40e8abc15baeb8fce990
85 Nc1e1cb4658734438a1c3add285e86112
86 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016179733
87 https://doi.org/10.1038/sj.bjc.6601686
88 schema:sdDatePublished 2021-11-01T18:08
89 schema:sdLicense https://scigraph.springernature.com/explorer/license/
90 schema:sdPublisher N7807a2ab7a584a40959d918e24a0430b
91 schema:url https://doi.org/10.1038/sj.bjc.6601686
92 sgo:license sg:explorer/license/
93 sgo:sdDataset articles
94 rdf:type schema:ScholarlyArticle
95 N129ac92d7c1d4285b9eac0eb548cfc50 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Gap Junctions
97 rdf:type schema:DefinedTerm
98 N15667ff0b6f44b32b6f1fc2f50df9a49 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Connexin 43
100 rdf:type schema:DefinedTerm
101 N1fb04c495c724e64a3c7ecf944456f43 rdf:first sg:person.01033631711.29
102 rdf:rest N80d59df296cf4c9d9d77c8a643e571ea
103 N2d7239151cc9467da89c8946db0a18fd schema:name pubmed_id
104 schema:value 15054470
105 rdf:type schema:PropertyValue
106 N465baf361c21402d890b6284163453ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Cells, Cultured
108 rdf:type schema:DefinedTerm
109 N5587baf87a2f4740a165cc1319249014 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Rats
111 rdf:type schema:DefinedTerm
112 N5ead4bf9f39947d5b30ea7c2356a12a1 schema:issueNumber 7
113 rdf:type schema:PublicationIssue
114 N5f7394dd03964b2badbdb46086d285ac schema:volumeNumber 90
115 rdf:type schema:PublicationVolume
116 N600cb264506f4127870fc7eb5c7bc378 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Cell Membrane Permeability
118 rdf:type schema:DefinedTerm
119 N723ebebfc95f42ccac5a619da7888473 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Cell Communication
121 rdf:type schema:DefinedTerm
122 N7414dc03f0974baf8cf2984dd6db9df1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Animals
124 rdf:type schema:DefinedTerm
125 N7807a2ab7a584a40959d918e24a0430b schema:name Springer Nature - SN SciGraph project
126 rdf:type schema:Organization
127 N7b4d61663b1b4891a6748683195aa6fc rdf:first sg:person.01345113105.80
128 rdf:rest N8b62be24c83a4d309b3e5e6c6e5b0c76
129 N80d59df296cf4c9d9d77c8a643e571ea rdf:first sg:person.01072542354.75
130 rdf:rest Nff03c6ccd5e64a6d8b6678e9a00494f7
131 N8b62be24c83a4d309b3e5e6c6e5b0c76 rdf:first sg:person.01342303001.27
132 rdf:rest Ne5331e8b414d4852908bf832846d90f1
133 Na4cbf7c5d24b4a6c9f07b8db56aaf6bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Phosphorylation
135 rdf:type schema:DefinedTerm
136 Nae98dbac909a40e8abc15baeb8fce990 schema:name dimensions_id
137 schema:value pub.1016179733
138 rdf:type schema:PropertyValue
139 Nb2a36d45a1fc4355bf98d8952d052120 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Dose-Response Relationship, Radiation
141 rdf:type schema:DefinedTerm
142 Nc17ffa3550ff4dffaa625b10ff004c7c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Bystander Effect
144 rdf:type schema:DefinedTerm
145 Nc1e1cb4658734438a1c3add285e86112 schema:name doi
146 schema:value 10.1038/sj.bjc.6601686
147 rdf:type schema:PropertyValue
148 Nc3d36648747f41a884c7b0d02a5e7dac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name X-Rays
150 rdf:type schema:DefinedTerm
151 Ne5331e8b414d4852908bf832846d90f1 rdf:first sg:person.013527444104.23
152 rdf:rest N1fb04c495c724e64a3c7ecf944456f43
153 Nff03c6ccd5e64a6d8b6678e9a00494f7 rdf:first sg:person.01163213535.14
154 rdf:rest rdf:nil
155 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
156 schema:name Medical and Health Sciences
157 rdf:type schema:DefinedTerm
158 anzsrc-for:1115 schema:inDefinedTermSet anzsrc-for:
159 schema:name Pharmacology and Pharmaceutical Sciences
160 rdf:type schema:DefinedTerm
161 sg:journal.1017082 schema:issn 0007-0920
162 1532-1827
163 schema:name British Journal of Cancer
164 schema:publisher Springer Nature
165 rdf:type schema:Periodical
166 sg:person.01033631711.29 schema:affiliation grid-institutes:grid.6572.6
167 schema:familyName Wharton
168 schema:givenName C W
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033631711.29
170 rdf:type schema:Person
171 sg:person.01072542354.75 schema:affiliation grid-institutes:grid.6572.6
172 schema:familyName Chipman
173 schema:givenName J K
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072542354.75
175 rdf:type schema:Person
176 sg:person.01163213535.14 schema:affiliation grid-institutes:grid.6572.6
177 schema:familyName Meldrum
178 schema:givenName R A
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163213535.14
180 rdf:type schema:Person
181 sg:person.01342303001.27 schema:affiliation grid-institutes:grid.76978.37
182 schema:familyName Botchway
183 schema:givenName S W
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342303001.27
185 rdf:type schema:Person
186 sg:person.01345113105.80 schema:affiliation grid-institutes:grid.6572.6
187 schema:familyName Edwards
188 schema:givenName G O
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01345113105.80
190 rdf:type schema:Person
191 sg:person.013527444104.23 schema:affiliation grid-institutes:grid.76978.37
192 schema:familyName Hirst
193 schema:givenName G
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013527444104.23
195 rdf:type schema:Person
196 sg:pub.10.1007/bf02110109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027282400
197 https://doi.org/10.1007/bf02110109
198 rdf:type schema:CreativeWork
199 sg:pub.10.1038/227680a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010419937
200 https://doi.org/10.1038/227680a0
201 rdf:type schema:CreativeWork
202 sg:pub.10.1054/bjoc.2000.1665 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045712049
203 https://doi.org/10.1054/bjoc.2000.1665
204 rdf:type schema:CreativeWork
205 grid-institutes:grid.6572.6 schema:alternateName School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
206 schema:name School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
207 rdf:type schema:Organization
208 grid-institutes:grid.76978.37 schema:alternateName Rutherford Appleton Laboratory, Chilton, Oxfordshire OX11 0QX, UK
209 schema:name Rutherford Appleton Laboratory, Chilton, Oxfordshire OX11 0QX, UK
210 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...