Long noncoding RNA and mRNA expression profiles following igf3 knockdown in common carp, Cyprinus carpio View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-02-19

AUTHORS

Feibiao Song, Lanmei Wang, Wenbin Zhu, Zaijie Dong

ABSTRACT

As a novel IGF system member, igf3 plays an important role in gonadal development of teleost fish. Although studies have reported the unusual expression of igf3 in fish gonad, whether the igf3 affects the expression of long noncoding RNAs (lncRNAs) in gonad remains unknown. In this study, an igf3 knockdown common carp (Cyprinus carpio) model was established by RNA interference. Then RNA sequencing of C. carpio gonad after igf3 knockdown was performed. A total of 327,169,410 and 306,305,018 clean reads were identified from control and igf3-dsRNA interference group, respectively. After a stringent filtering, RNA-seq yielded 14199 lncRNA and 106932 mRNA transcripts with 124 and 353 differentially expressed lncRNAs and mRNAs. Our dataset provides an extensive resource for understanding the potential regulatory molecular mechanism of igf3 in early stage of gonadal development in C. carpio. More... »

PAGES

190024

Journal

TITLE

Scientific Data

ISSUE

N/A

VOLUME

6

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sdata.2019.24

DOI

http://dx.doi.org/10.1038/sdata.2019.24

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112220806

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30778253


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